Prenatal maternal stress predicts childhood asthma in girls: project ice storm.

Abstract:

:Little is known about how prenatal maternal stress (PNMS) influences risks of asthma in humans. In this small study, we sought to determine whether disaster-related PNMS would predict asthma risk in children. In June 1998, we assessed severity of objective hardship and subjective distress in women pregnant during the January 1998 Quebec Ice Storm. Lifetime asthma symptoms, diagnoses, and corticosteroid utilization were assessed when the children were 12 years old (N = 68). No effects of objective hardship or timing of the exposure were found. However, we found that, in girls only, higher levels of prenatal maternal subjective distress predicted greater lifetime risk of wheezing (OR = 1.11; 90% CI = 1.01-1.23), doctor-diagnosed asthma (OR = 1.09; 90% CI = 1.00-1.19), and lifetime utilization of corticosteroids (OR = 1.12; 90% CI = 1.01-1.25). Other perinatal and current maternal life events were also associated with asthma outcomes. Findings suggest that stress during pregnancy opens a window for fetal programming of immune functioning. A sex-based approach may be useful to examine how prenatal and postnatal environments combine to program the immune system. This small study needs to be replicated with a larger, more representative sample.

journal_name

Biomed Res Int

authors

Turcotte-Tremblay AM,Lim R,Laplante DP,Kobzik L,Brunet A,King S

doi

10.1155/2014/201717

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

201717

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章
  • Possible Effect of Concomitant Prokinetics and Herbal Medicines against Nausea in Patients Taking Lubiprostone.

    abstract:Background and Aim:Lubiprostone is a novel laxative that sometimes causes nausea, but preventive strategies remain unconfirmed. Methods:We retrospectively chose 126 patients prescribed lubiprostone from 2013 to 2016. Medical records were reviewed to clarify whether nausea developed after administration of the drug. Ba...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/3762179

    authors: Yamamoto T,Osumi S,Yanagisawa D,Yamato H,Aoyagi H,Isono A,Abe K,Kita H

    更新日期:2017-01-01 00:00:00

  • A light-field-based method to adjust on-axis rounded leaf end MLC position to predict off-axis MLC penumbra region dosimetric performance in a radiation therapy planning system.

    abstract:PURPOSE:An analytical and experimental study of split shape dose calculation correction by adjusting the position of the on-axis round leaf end position is presented. We use on-axis corrected results to predict off-axis penumbra region dosimetric performance in an intensity-modulated radiation therapy treatment plannin...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/461801

    authors: Wu JM,Lee TF,Yeh SA,Hsiao KY,Chen HH,Chao PJ,Chen YT

    更新日期:2013-01-01 00:00:00

  • Donor and Recipient Outcomes following Robotic-Assisted Laparoscopic Living Donor Nephrectomy: A Systematic Review.

    abstract:Aims:We aimed to summarize available lines of evidence about intraoperative and postoperative donor outcomes following robotic-assisted laparoscopic donor nephrectomy (RALDN) as well as outcomes of graft and recipients. Methods:A systematic review of PubMed/Medline, ISI Web of Knowledge, and Scopus databases was perfo...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2019/1729138

    authors: Creta M,Calogero A,Sagnelli C,Peluso G,Incollingo P,Candida M,Minieri G,Longo N,Fusco F,Tammaro V,Dodaro CA,Mangiapia F,Carlomagno N

    更新日期:2019-04-22 00:00:00

  • High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma.

    abstract::Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) is a mitochondrial inner membrane protein and plays an important role in mitochondrial ATP production and biogenesis. High expression levels of LETM1 have been correlated with numerous human malignancies. This study explored the clinicopathological sign...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/850316

    authors: Chen L,Yang Y,Liu S,Piao L,Zhang Y,Lin Z,Li Z

    更新日期:2014-01-01 00:00:00

  • LncRNA BLACAT1 May Serve as a Prognostic Predictor in Cancer: Evidence from a Meta-Analysis.

    abstract:Background:As a newly discovered lncRNA, bladder cancer-associated transcript 1 (BLACAT1) has been reported to correlate with poor clinical outcomes in several different cancers. This study aimed to evaluate its generalized predictive value for cancer prognosis. Materials and Methods:We thoroughly searched PubMed, Emb...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/1275491

    authors: Lu H,Liu H,Yang X,Ye T,Lv P,Wu X,Ye Z

    更新日期:2019-04-02 00:00:00

  • Tranexamic Acid Combined with Compression Bandage Following Total Knee Arthroplasty Promotes Blood Coagulation: A Retrospective Analysis.

    abstract:Objective:This paper included a retrospective review of the effect of tranexamic acid (TXA) combined with pressure bandaging on hemostasis of patients who received a unilateral total knee arthroplasty (TKA) from 2017 to 2019. Methods:A total of 197 patients undergoing TKA were chosen to be classified into 2 groups, th...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/2739560

    authors: Li GH,Ding LM,Sun L,Wang F

    更新日期:2020-11-02 00:00:00

  • Whole Body Vibration Retards Progression of Atherosclerosis via Insulin-Like Growth Factor 1 in Apolipoprotein E-Deficient Mice.

    abstract::Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE-/-) AS mice, which were trained by WBV (15 Hz, 30 m...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/4934861

    authors: Wu H,Zhang Y,Yang X,Li X,Shao Z,Zhou Z,Li Y,Pan S,Liu C

    更新日期:2018-03-07 00:00:00

  • Comparison of the Superior and Inferior Rectus Muscles in Humans: An Anatomical Study with Notes on Morphology, Anatomical Variations, and Intramuscular Innervation Patterns.

    abstract::A comparison of the superior and inferior rectus muscles was performed to determine whether they have similar structures and innervation attributable to their participation in the same type of, although antagonistic, eye movements. The study was conducted on 70 cadaveric hemiheads, and the anatomical variations in the...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9037693

    authors: Haładaj R,Polguj M,Tubbs RS

    更新日期:2020-04-30 00:00:00

  • The Emerging Role of lncRNAs in Spinal Cord Injury.

    abstract::Spinal cord injury (SCI) is a highly debilitating disease and is increasingly being recognized as an important global health priority. However, the mechanisms underlying SCI have not yet been fully elucidated, and effective therapies for SCI are lacking. Long noncoding RNAs (lncRNAs), which form a major class of nonco...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/3467121

    authors: Wang F,Liu J,Wang X,Chen J,Kong Q,Ye B,Li Z

    更新日期:2019-10-15 00:00:00

  • Moringa peregrina Leaves Extracts Induce Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma.

    abstract::Moringa grows in the tropical and subtropical regions of the world. The genus Moringa belongs to family Moringaceae. It is found to possess various medicinal uses including hypoglycemic, analgesic, anti-inflammatory, hypolipidemic, and antioxidant activities. In this study, we investigated the antimicrobial and the an...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/2698570

    authors: Mansour M,Mohamed MF,Elhalwagi A,El-Itriby HA,Shawki HH,Abdelhamid IA

    更新日期:2019-01-01 00:00:00

  • Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer.

    abstract::Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and stro...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8835398

    authors: Zeng Y,Tang CH,Wang Y,Lu HJ,Huang BF,Wang Q,Shao JK,Jin LL,Wang CQ,Teng LS

    更新日期:2020-11-28 00:00:00

  • Acinetobacter baumannii Infection in Transfusion Dependent Thalassemia Patients with Sepsis.

    abstract:PURPOSE:To identify the Acinetobacter baumannii infection among transfusion dependent thalassemia patients. METHODS:A quantitative approach was employed to assess Acinetobacter baumannii infection in transfusion dependent thalassemia patients. Samples were collected from 916 patients, which have shown bacterial growth...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2351037

    authors: Abdul Rasheed M,Alzahrani FM,Sattar Shaikh S

    更新日期:2017-01-01 00:00:00

  • Extremely low frequency magnetic fields induce spermatogenic germ cell apoptosis: possible mechanism.

    abstract::The energy generated by an extremely low frequency electromagnetic field (ELF-EMF) is too weak to directly induce genotoxicity. However, it is reported that an extremely low frequency magnetic field (ELF-MF) is related to DNA strand breakage and apoptosis. The testes that conduct spermatogenesis through a dynamic cell...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/567183

    authors: Lee SK,Park S,Gimm YM,Kim YW

    更新日期:2014-01-01 00:00:00

  • PPI network analysis of mRNA expression profile of ezrin knockdown in esophageal squamous cell carcinoma.

    abstract::Ezrin, coding protein EZR which cross-links actin filaments, overexpresses and involves invasion, metastasis, and poor prognosis in various cancers including esophageal squamous cell carcinoma (ESCC). In our previous study, Ezrin was knock down and analyzed by mRNA expression profile which has not been fully mined. In...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/651954

    authors: Wu B,Xie J,Du Z,Wu J,Zhang P,Xu L,Li E

    更新日期:2014-01-01 00:00:00

  • Monitoring Minimal Residual Disease in the Myeloproliferative Neoplasms: Current Applications and Emerging Approaches.

    abstract::The presence of acquired mutations within the JAK2, CALR, and MPL genes in the majority of patients with myeloproliferative neoplasms (MPN) affords the opportunity to utilise these mutations as markers of minimal residual disease (MRD). Reduction of the mutated allele burden has been reported in response to a number o...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2016/7241591

    authors: Haslam K,Langabeer SE

    更新日期:2016-01-01 00:00:00

  • Comprehensive Evaluation of Personal, Clinical, and Radiation Dosimetric Parameters for Acute Skin Reaction during Whole Breast Radiotherapy.

    abstract::Skin reaction is major problem during whole breast radiotherapy. To identify factors related to skin reactions during whole breast radiotherapy, various personal, clinical, and radiation dosimetric parameters were evaluated. From January 2012 to December 2013, a total of 125 patients who underwent breast conserving su...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/3656574

    authors: Yang DS,Lee JA,Yoon WS,Lee NK,Park YJ,Lee S,Kim CY,Son GS

    更新日期:2016-01-01 00:00:00

  • Meta-analysis: the efficacy and safety of paricalcitol for the treatment of secondary hyperparathyroidism and proteinuria in chronic kidney disease.

    abstract:INTRODUCTION:Previous studies have demonstrated the safety and efficacy of using Paricalcitol for the treatment of secondary hyperparathyroidism (SHPT) in patients on dialysis. The aim of the current meta-analysis was to assess the safety and efficacy of Paricalcitol for the management of SHPT in patients with chronic ...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2013/320560

    authors: Han T,Rong G,Quan D,Shu Y,Liang Z,She N,Liu M,Yang B,Cheng G,Lv Y,Stern L

    更新日期:2013-01-01 00:00:00

  • Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors.

    abstract::A series of halo-substituted mixed ester/amide-based analogues 4a-l have been prepared as jack bean urease inhibitor, which showed good to excellent inhibition of enzyme activity. The role of halo-substituted benzoyl moieties and alkyl substituted anilines in urease inhibitory kinetics was also investigated. The alkyl...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8867407

    authors: Rashid M,Rafique H,Roshan S,Shamas S,Iqbal Z,Ashraf Z,Abbas Q,Hassan M,Qureshi ZUR,Asad MHHB

    更新日期:2020-12-24 00:00:00

  • 3D Culture of MIN-6 Cells on Decellularized Pancreatic Scaffold: In Vitro and In Vivo Study.

    abstract::Type 1 diabetes is an autoimmune disease which is due to the lack of β cells. The ideal therapy to cure the disease is pancreas transplantation, but its application is confined to a limited number of people due to the shortage of organ and the need for life-long immunosuppression. Regenerative medicine methods such as...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/432645

    authors: Wu D,Wan J,Huang Y,Guo Y,Xu T,Zhu M,Fan X,Zhu S,Ling C,Li X,Lu J,Zhu H,Zhou P,Lu Y,Wang Z

    更新日期:2015-01-01 00:00:00

  • Intestinal Perforation in ACTH-Dependent Cushing's Syndrome.

    abstract::Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred mo...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1155/2019/9721781

    authors: Shahidi M,Phillips RA,Chik CL

    更新日期:2019-03-13 00:00:00

  • Prenatal Diagnosis of Central Nervous System Anomalies by High-Resolution Chromosomal Microarray Analysis.

    abstract::The aims of this study were to evaluate the contribution of chromosomal microarray analysis (CMA) in the prenatal diagnosis of fetuses with central nervous system (CNS) anomalies but normal chromosomal karyotype. A total of 46 fetuses with CNS anomalies with or without other ultrasound anomalies but normal karyotypes ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/426379

    authors: Sun L,Wu Q,Jiang SW,Yan Y,Wang X,Zhang J,Liu Y,Yao L,Ma Y,Wang L

    更新日期:2015-01-01 00:00:00

  • Early aging in Chernobyl clean-up workers: long-term study.

    abstract::This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/948473

    authors: Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

    更新日期:2015-01-01 00:00:00

  • Public versus Private Healthcare Systems following Discharge from the ICU: A Propensity Score-Matched Comparison of Outcomes.

    abstract::Purpose. The long-term outcomes of patients after discharge from tertiary ICUs as they relate to the public versus private healthcare systems in Brazil have not yet been evaluated. Materials and Methods. A multicenter prospective cohort study was conducted to compare the all-cause mortality and the physical functional...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/6568531

    authors: Dexheimer Neto FL,Rosa RG,Duso BA,Haas JS,Savi A,Cabral Cda R,Maccari JG,de Oliveira RP,Antônio AC,Castro Pde S,Teixeira C

    更新日期:2016-01-01 00:00:00

  • Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions.

    abstract::Diabetic foot ulcers (DFUs) are characterized by an unsatisfactory inflammatory and migratory response. Skin inflammation involves the participation of many cells and particularly macrophages. Macrophage function can be modulated by neuropeptides; however, little is known regarding the role of neurotensin (NT) as a mo...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/941764

    authors: Moura LI,Silva L,Leal EC,Tellechea A,Cruz MT,Carvalho E

    更新日期:2013-01-01 00:00:00

  • Boosting Secondary Metabolite Production and Discovery through the Engineering of Novel Microbial Biosensors.

    abstract::Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/7021826

    authors: de Frias UA,Pereira GKB,Guazzaroni ME,Silva-Rocha R

    更新日期:2018-07-09 00:00:00

  • HPV Testing from Dried Urine Spots as a Tool for Cervical Cancer Screening in Low-Income Countries.

    abstract::Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried ur...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2015/283036

    authors: Frati ER,Martinelli M,Fasoli E,Colzani D,Bianchi S,Binda S,Olivani P,Tanzi E

    更新日期:2015-01-01 00:00:00

  • Inter- and Intraspecific Variations in the Pectoral Muscles of Common Chimpanzees (Pan troglodytes), Bonobos (Pan paniscus), and Humans (Homo sapiens).

    abstract::We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens). We have macroscopically dissected these muscles in six adult Pan troglodytes, ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9404508

    authors: Potau JM,Arias-Martorell J,Bello-Hellegouarch G,Casado A,Pastor JF,de Paz F,Diogo R

    更新日期:2018-01-21 00:00:00

  • Overexpression of MicroRNA-122 Resists Oxidative Stress-Induced Human Umbilical Vascular Endothelial Cell Injury by Inhibition of p53.

    abstract::Deep venous thrombosis (DVT) constitutes a great threat to health worldwide. Endothelial cell injury and dysfunction comprise the critical contributor for the development of DVT. However, the mechanism behind it remains poorly elucidated. The study is aimed at investigating the role of microRNA-122 (miR-122) and oxida...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9791608

    authors: Li HQ,Pan ZY,Yang Z,Zhang DB,Chen Q

    更新日期:2020-10-27 00:00:00

  • Resistin Enhances Inflammatory Cytokine Production in Coronary Artery Tissues by Activating the NF-κB Signaling.

    abstract::Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/3296437

    authors: Gao F,Si F,Feng S,Yi Q,Liu R

    更新日期:2016-01-01 00:00:00

  • Kinematic Validation of Postural Sway Measured by Biodex Biosway (Force Plate) and SWAY Balance (Accelerometer) Technology.

    abstract:Background:The Biodex Biosway® Balance System and SWAY Balance® Mobile smartphone application (SBMA) are portable instruments that assess balance function with force plate and accelerometer technology, respectively. The validity of these indirect clinical measures of postural sway merits investigation. Purpose:The pur...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/8185710

    authors: Dewan BM,Roger James C,Kumar NA,Sawyer SF

    更新日期:2019-12-21 00:00:00