Extremely low frequency magnetic fields induce spermatogenic germ cell apoptosis: possible mechanism.

Abstract:

:The energy generated by an extremely low frequency electromagnetic field (ELF-EMF) is too weak to directly induce genotoxicity. However, it is reported that an extremely low frequency magnetic field (ELF-MF) is related to DNA strand breakage and apoptosis. The testes that conduct spermatogenesis through a dynamic cellular process involving meiosis and mitosis seem vulnerable to external stress such as heat, MF exposure, and chemical or physical agents. Nevertheless the results regarding adverse effects of ELF-EMF on human or animal reproductive functions are inconclusive. According to the guideline of the International Commission on Non-Ionizing Radiation Protection (ICNIRP; 2010) for limiting exposure to time-varying MF (1 Hz to 100 kHz), overall conclusion of epidemiologic studies has not consistently shown an association between human adverse reproductive outcomes and maternal or paternal exposure to low frequency fields. In animal studies there is no compelling evidence of causal relationship between prenatal development and ELF-MF exposure. However there is increasing evidence that EL-EMF exposure is involved with germ cell apoptosis in testes. Biophysical mechanism by which ELF-MF induces germ cell apoptosis has not been established. This review proposes the possible mechanism of germ cell apoptosis in testes induced by ELF-MF.

journal_name

Biomed Res Int

authors

Lee SK,Park S,Gimm YM,Kim YW

doi

10.1155/2014/567183

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

567183

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章,评审
  • Factors Influencing Administration, Recognition, and Compliance of Medicine among Community Residents from Jilin Province, China: A Questionnaire Study.

    abstract:Introduction:To identify and analyze factors that influence administration, recognition, and compliance of medicine among community residents in Jilin Province, China. Methods:A survey was carried out among 2417 community residents in Jilin Province, China, to study their administration (CRA), recognition (CRR), and c...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8730212

    authors: Song YQ,Zhang WR,Zhang SX,Wang TH,Jiang Z,Meng CF,Zhang TZ,Xin QZ,Cao KJ,Zhang Y,Sun Y

    更新日期:2020-07-18 00:00:00

  • Somatostatin receptor based imaging and radionuclide therapy.

    abstract::Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/917968

    authors: Xu C,Zhang H

    更新日期:2015-01-01 00:00:00

  • Simvastatin combined with antioxidant attenuates the cerebral vascular endothelial inflammatory response in a rat traumatic brain injury.

    abstract::Traumatic brain injury (TBI) leads to important and deleterious neuroinflammation, as evidenced by indicators such as edema, cytokine production, induction of nitric oxide synthase, and leukocyte infiltration. After TBI, cerebral vascular endothelial cells play a crucial role in the pathogenesis of inflammation. In ou...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/910260

    authors: Wang KW,Wang HK,Chen HJ,Liliang PC,Liang CL,Tsai YD,Cho CL,Lu K

    更新日期:2014-01-01 00:00:00

  • Aberrant Methylation and Differential Expression of SLC2A1, TNS4, GAPDH, ATP8A2, and CASZ1 Are Associated with the Prognosis of Lung Adenocarcinoma.

    abstract::Lung cancer is one of the leading triggers for cancer death worldwide. In this study, the relationship of the aberrantly methylated and differentially expressed genes in lung adenocarcinoma (LUAD) with cancer prognosis was investigated, and 5 feature genes were identified eventually. Specifically, we firstly downloade...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/1807089

    authors: Wang X,Shi D,Zhao D,Hu D

    更新日期:2020-09-25 00:00:00

  • Electrophysiological and Behavioral Responses of Theocolax elegans (Westwood) (Hymenoptera: Pteromalidae) to Cereal Grain Volatiles.

    abstract::Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-produ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/5460819

    authors: Germinara GS,De Cristofaro A,Rotundo G

    更新日期:2016-01-01 00:00:00

  • Are Janus Kinase Inhibitors Superior over Classic Biologic Agents in RA Patients?

    abstract::The Janus Kinases (JAKs) are a family of intracellular tyrosine kinases that provide transmission signals from cytokine, interferons, and many hormones receptors to the nucleus resulting in synthesis of many biologically active compounds and changing cell metabolism and function. That was theoretical background to syn...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/7492904

    authors: Kotyla PJ

    更新日期:2018-05-10 00:00:00

  • Predicting the types of J-proteins using clustered amino acids.

    abstract::J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer propertie...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/935719

    authors: Feng P,Lin H,Chen W,Zuo Y

    更新日期:2014-01-01 00:00:00

  • Pinelliae Rhizoma Praeparatum Cum Alumine Extract: Sedative and Hypnotic Effects in Mice and Component Compounds.

    abstract::Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/6198067

    authors: Lin S,Nie B,Song K,Ye R,Yuan Z

    更新日期:2019-04-28 00:00:00

  • Systemic and Ocular Hemodynamic Risk Factors in Glaucoma.

    abstract::Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the dise...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/141905

    authors: Choi J,Kook MS

    更新日期:2015-01-01 00:00:00

  • Boosting Secondary Metabolite Production and Discovery through the Engineering of Novel Microbial Biosensors.

    abstract::Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/7021826

    authors: de Frias UA,Pereira GKB,Guazzaroni ME,Silva-Rocha R

    更新日期:2018-07-09 00:00:00

  • Progress in the identification of dengue virus entry/fusion inhibitors.

    abstract::Dengue fever, a reemerging disease, is putting nearly 2.5 billion people at risk worldwide. The number of infections and the geographic extension of dengue fever infection have increased in the past decade. The disease is caused by the dengue virus, a flavivirus that uses mosquitos Aedes sp. as vectors. The disease ha...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/825039

    authors: De La Guardia C,Lleonart R

    更新日期:2014-01-01 00:00:00

  • Enhanced Production of Polymyxin E in Paenibacillus polymyxa by Replacement of Glucose by Starch.

    abstract::Polymyxin E or colistin, produced by Paenibacillus polymyxa, is an important antibiotic against Gram-negative pathogens. The objective of this study is to evaluate the effect of starch in fermentation medium on colistin biosynthesis in P. polymyxa. The results indicated that replacement of glucose by starch stimulated...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/1934309

    authors: Yu Z,Sun Z,Yin J,Qiu J

    更新日期:2018-10-14 00:00:00

  • Mortality and Cardiovascular Complications in Older Complex Chronic Patients with Type 2 Diabetes.

    abstract:AIMS/INTRODUCTION:Determining the prevalence of diabetes and its cardiovascular complications and all-cause mortality in older chronic complex patients. MATERIALS AND METHODS:We carried out a multicenter retrospective study and included a randomized sample of 932 CCP people. We assessed the prevalence of diabetes acco...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/6078498

    authors: Clua-Espuny JL,González-Henares MA,Queralt-Tomas MLL,Campo-Tamayo W,Muria-Subirats E,Panisello-Tafalla A,Lucas-Noll J

    更新日期:2017-01-01 00:00:00

  • Andrographolide Inhibits Proliferation and Metastasis of SGC7901 Gastric Cancer Cells.

    abstract::To explore the mechanisms by which andrographolide inhibits gastric cancer cell proliferation and metastasis, we employed the gastric cell line SGC7901 to investigate the anticancer effects of andrographolide. The cell survival ratio, cell migration and invasion, cell cycle, apoptosis, and matrix metalloproteinase act...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/6242103

    authors: Dai L,Wang G,Pan W

    更新日期:2017-01-01 00:00:00

  • Changes in Lower Limb Muscle Activation and Degree of Weight Support according to Types of Cane-Supported Gait in Hemiparetic Stroke Patients.

    abstract::This study was aimed at investigating the changes in the degree of weight support loaded on the cane and paretic-side lower limb muscle activation according to the types of cane and cane-supported gait using a weight-support feedback cane (WSFC). Eleven hemiparetic stroke patients were recruited from a local rehabilit...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9127610

    authors: Choi EP,Yang SJ,Jung AH,Na HS,Kim YO,Cho KH

    更新日期:2020-09-23 00:00:00

  • In Vivo Imaging of Neutrophil Extracellular Traps (NETs): Visualization Methods and Outcomes.

    abstract::Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4192745

    authors: Alasmari SZ

    更新日期:2020-02-01 00:00:00

  • A Rapid Detection Method for Morphological Characteristics of Biological Cells Based on Phase Imaging.

    abstract::This paper presents a rapid label-free method for the identification of morphological characteristics of biological cells. Based on quantitative phase microscopy as well as the connotation of phase value, the gradient operator of phase and the associated analytic processing are employed to determine the edge of differ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/4651639

    authors: Tang WB,Ji Y,Zhang MM,Chen ZY,Xu YY,Wang YW

    更新日期:2018-04-11 00:00:00

  • Prevalence of Cam and Pincer Deformities in the X-Rays of Asymptomatic Individuals.

    abstract:Objective:The presence of radiological signs of femoroacetabular impingement (FAI) is not necessarily associated with symptoms. Hence, the prevalence of cam and pincer deformities in the overall population may be underestimated. The purpose of this study was to screen an unselected cohort of people without hip symptoms...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8562329

    authors: Thier S,Gerisch D,Weiss C,Fickert S,Brunner A

    更新日期:2017-01-01 00:00:00

  • Rare Mutations in AHDC1 in Patients with Obstructive Sleep Apnea.

    abstract:Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5907361

    authors: Yang S,Li K,Zhu MM,Yuan XD,Jiao XL,Yang YY,Li J,Li L,Zhang HN,Du YH,Wei YX,Qin YW

    更新日期:2019-10-13 00:00:00

  • Sliding and lower limb mechanics during sit-stand-sit transitions with a standing wheelchair.

    abstract:PURPOSE:This study aimed to investigate the shear displacement between the body and backrest/seat, range of motion (ROM), and force acting on the lower limb joints during sit-stand-sit transitions by operating an electric-powered standing wheelchair. METHODS AND MATERIALS:The amounts of sliding along the backrest and ...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/236486

    authors: Yang YS,Chen MD,Fang WC,Chang JJ,Kuo CC

    更新日期:2014-01-01 00:00:00

  • A Drosophila Model for Screening Antiobesity Agents.

    abstract::Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/6293163

    authors: Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

    更新日期:2016-01-01 00:00:00

  • The establishment of metabolic syndrome model by induction of fructose drinking water in male Wistar rats.

    abstract:BACKGROUND:Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. AIMS:To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW) in male Wistar rats. METHODS:Eighteen male Wistar rats were fed with FDW 20%...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/263897

    authors: Mamikutty N,Thent ZC,Sapri SR,Sahruddin NN,Mohd Yusof MR,Haji Suhaimi F

    更新日期:2014-01-01 00:00:00

  • The Emerging Role of lncRNAs in Spinal Cord Injury.

    abstract::Spinal cord injury (SCI) is a highly debilitating disease and is increasingly being recognized as an important global health priority. However, the mechanisms underlying SCI have not yet been fully elucidated, and effective therapies for SCI are lacking. Long noncoding RNAs (lncRNAs), which form a major class of nonco...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/3467121

    authors: Wang F,Liu J,Wang X,Chen J,Kong Q,Ye B,Li Z

    更新日期:2019-10-15 00:00:00

  • Trunk and shoulder kinematic and kinetic and electromyographic adaptations to slope increase during motorized treadmill propulsion among manual wheelchair users with a spinal cord injury.

    abstract::The main objective was to quantify the effects of five different slopes on trunk and shoulder kinematics as well as shoulder kinetic and muscular demands during manual wheelchair (MWC) propulsion on a motorized treadmill. Eighteen participants with spinal cord injury propelled their MWC at a self-selected constant spe...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/636319

    authors: Gagnon D,Babineau AC,Champagne A,Desroches G,Aissaoui R

    更新日期:2015-01-01 00:00:00

  • Angelica gigas Nakai Has Synergetic Effects on Doxorubicin-Induced Apoptosis.

    abstract::Natural products are valuable sources for drug discovery because they have a wide variety of useful chemical components and biological properties. A quick reevaluation of the potential therapeutic properties of established natural products was made possible by the recent development of the methodology and improvement ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/6716547

    authors: Jeon YJ,Shin JI,Lee S,Lee YG,Kim JB,Kwon HC,Kim SH,Kim I,Lee K,Han YS

    更新日期:2018-08-01 00:00:00

  • Comparison of Clinical Outcomes of Two-Level PELD and Foraminoplasty PELD for Highly Migrated Disc Herniations: A Comparative Study.

    abstract:Objective:The aim of this study is to compare the clinical outcomes of two-level percutaneous endoscopic lumbar discectomy (PELD) and foraminoplasty PELD in treating highly migrated lumbar disc herniations. Methods:Patients with highly migrated lumbar disc herniations were enrolled from May 2014 to June 2016. Low back...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/9681424

    authors: Wu X,Fan G,He S,Gu X,Yang Y

    更新日期:2019-10-13 00:00:00

  • Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain.

    abstract::Perinatal infections have a negative impact on brain development. However, the underlying mechanisms leading to neurological impairment are not completely understood and reliable models of inflammation are urgently needed. Using phorbol-myristate-acetate as an activator of inflammation, we investigated the effect on t...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/318306

    authors: Dzietko M,Hahnemann M,Polley O,Sifringer M,Felderhoff-Mueser U,Bührer C

    更新日期:2015-01-01 00:00:00

  • The Alcohol Extract of Coreopsis tinctoria Nutt Ameliorates Diabetes and Diabetic Nephropathy in db/db Mice through miR-192/miR-200b and PTEN/AKT and ZEB2/ECM Pathways.

    abstract::The study aims to investigate the effects of the alcohol extract of Coreopsis tinctoria Nutt (AC) on diabetic nephropathy (DN) mice. A total of 30 db/db (DN) mice were divided into 3 groups, which were treated with AC (300 mg/kg/day), metformin (180 mg/kg/day), or saline by gavage for 10 weeks. Ten db/m mice treated w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5280514

    authors: Yu S,Zhao H,Yang W,Amat R,Peng J,Li Y,Deng K,Mao X,Jiao Y

    更新日期:2019-03-28 00:00:00

  • A Naphthalenic Derivative ND-1 Inhibits Thrombus Formation by Interfering the Binding of Fibrinogen to Integrin αIIbβ3.

    abstract::Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, researches on the deve...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8587164

    authors: Ding X,Liu TD,Xie ZL,Zhao Q,Cao Y,Liu XD,Wang CH,Gamariel RR,Ming X,Li ZY,Kong Y

    更新日期:2016-01-01 00:00:00

  • A Decision for Predicting Successful Extubation of Patients in Intensive Care Unit.

    abstract::Approximately 40% of patients admitted to the medical intensive care unit (ICU) require mechanical ventilation. An accurate prediction of successful extubation in patients is a key clinical problem in ICU due to the fact that the successful extubation is highly associated with prolonged ICU stay. The prolonged ICU sta...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/6820975

    authors: Tu CS,Chang CH,Chang SC,Lee CS,Chang CT

    更新日期:2018-01-04 00:00:00