Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer.

abstract：:Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal art...

journal_title：BioMed research international

authors： Buys-Gonçalves GF,Abreu LAS,Gregorio BM,Sampaio FJB,Pereira-Sampaio MA,de Souza DB

更新日期：2019-02-07 00:00:00

abstract：:Since proteins carry out their functions through interactions with other molecules, accurately identifying the protein-ligand binding site plays an important role in protein functional annotation and rational drug discovery. In the past two decades, a lot of algorithms were present to predict the protein-ligand bindin...

journal_title：BioMed research international

authors： Wang K,Gao J,Shen S,Tuszynski JA,Ruan J,Hu G

更新日期：2013-01-01 00:00:00

abstract：:We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with glass tubes in Chouckroun's leukocyte- and platelet-rich fibrin (L-PRF) method. In this study, w...

journal_title：BioMed research international

authors： Tunalı M,Özdemir H,Küçükodacı Z,Akman S,Yaprak E,Toker H,Fıratlı E

更新日期：2014-01-01 00:00:00

abstract：:Iodinated contrast (IC) is clinically used in diagnostic and interventional procedures, but its use can result in contrast-induced acute kidney injury (CI-AKI). Chronic kidney disease (CKD) and chronic hyperglycemia (CH) are important predisposing factors to CI-AKI. The aim of this study was to investigate the impact ...

journal_title：BioMed research international

authors： Fernandes SM,Martins DM,da Fonseca CD,Watanabe M,Vattimo Mde F

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to investigate the influence of a topically administered hygienic preparation containing a 3% ethanolic extract of Brazilian green propolis (EEP-B) on oral microflora spectrum changes in a group of patients who underwent common oral surgery procedures. Two gel samples were compared: the teste...

journal_title：BioMed research international

authors： Morawiec T,Mertas A,Wojtyczka RD,Niedzielska I,Dziedzic A,Bubiłek-Bogacz A,Sender J,Wróbel J,Tanasiewicz M,Wesołowski P,Król W

更新日期：2015-01-01 00:00:00

abstract：:The study of the normal function and pathology of the inner ear has unique difficulties as it is inaccessible during life and, so, conventional techniques of pathologic studies such as biopsy and surgical excision are not feasible, without further impairing function. Mathematical modelling is therefore particularly at...

journal_title：BioMed research international

authors： Bellos C,Rigas G,Spiridon IF,Bibas A,Iliopoulou D,Böhnke F,Koutsouris D,Fotiadis DI

更新日期：2014-01-01 00:00:00

abstract：:Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediter...

journal_title：BioMed research international

authors： Karygianni L,Cecere M,Skaltsounis AL,Argyropoulou A,Hellwig E,Aligiannis N,Wittmer A,Al-Ahmad A

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Vasculogenic mimicry (VM) was related to invasion and metastasis of head and neck squamous cell carcinoma (HNSCC) patients. This study was designed to investigate the role of EphA2 in VM formation of HNSCC. METHODS:The SiRNA technique was used to knock down the expression of EphA2 in vitro. The ability of cell...

journal_title：BioMed research international

authors： Wang W,Lin P,Sun B,Zhang S,Cai W,Han C,Li L,Lu H,Zhao X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

journal_title：BioMed research international

authors： Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

更新日期：2016-01-01 00:00:00

abstract：Background:Low birth weight is the leading cause of infant and child mortality and contributes to several poor health outcomes. Proper knowledge of risk factors of low birth weight is important for identifying those mothers at risk and thereby for planning and taking appropriate actions. This study investigates factors...

journal_title：BioMed research international

authors： Hailu LD,Kebede DL

更新日期：2018-04-23 00:00:00

abstract：:Two fullerene derivatives (fullerenes 1 and 2), bearing a hydrophilic chain on the pyrrolidinic nitrogen, were developed with the aim to deliver anticancer agents to solid tumors. These two compounds showed a significantly different behaviour on human neoplastic cell lines in vitro in respect to healthy leukocytes. In...

journal_title：BioMed research international

authors： Pacor S,Grillo A,Đorđević L,Zorzet S,Lucafò M,Da Ros T,Prato M,Sava G

更新日期：2015-01-01 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：:Estimation of the spread and advancement of Plasmodium falciparum artemisinin-resistant parasites can be done by probing polymorphisms in the kelch (Pfk13) domain (a validated molecular marker). This study aimed to provide baseline information for future artemisinin surveillance by analyzing the k13-propeller domain i...

journal_title：BioMed research international

authors： Rana R,Ranjit M,Bal M,Khuntia HK,Pati S,Krishna S,Das A

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl2 on autophagy and muscle atrophy are still unclear. METHODS:C2C12 myotubes were exposed to increasing concentrat...

journal_title：BioMed research international

authors： Chen R,Jiang T,She Y,Xu J,Li C,Zhou S,Shen H,Shi H,Liu S

更新日期：2017-01-01 00:00:00

abstract：:Oil palm (Elaeis guineensis Jacq) is one of the major sources of edible oil. Reducing the effect of Ganoderma, main cause of basal stem rot (BSR) on oil palm, is the main propose of this study. Understanding the oil palm defense mechanism against Ganoderma infection through monitoring changes in the secondary metaboli...

journal_title：BioMed research international

authors： Sahebi M,Hanafi MM,Mohidin H,Rafii MY,Azizi P,Idris AS,Fariz A,Abiri R,Taheri S,Moradpoor M

更新日期：2018-03-12 00:00:00

abstract：Background:The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. Methods:We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected with ferric ammonium ci...

journal_title：BioMed research international

authors： Xu W,Yu R,Zhu X,Li Z,Jia J,Li D,Chen Y,Zhang X

更新日期：2020-05-24 00:00:00

abstract：:This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of bl...

journal_title：BioMed research international

authors： Zhang Q,Zhang Y,Zhou Y,Zhang K,Zhang K,Gao L

更新日期：2016-01-01 00:00:00

abstract：:Deep venous thrombosis (DVT) constitutes a great threat to health worldwide. Endothelial cell injury and dysfunction comprise the critical contributor for the development of DVT. However, the mechanism behind it remains poorly elucidated. The study is aimed at investigating the role of microRNA-122 (miR-122) and oxida...

journal_title：BioMed research international

authors： Li HQ,Pan ZY,Yang Z,Zhang DB,Chen Q

更新日期：2020-10-27 00:00:00

abstract：:Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...

journal_title：BioMed research international

authors： Farini A,Sitzia C,Erratico S,Meregalli M,Torrente Y

更新日期：2014-01-01 00:00:00

abstract：:A study of myelostimulating activity of ionic compounds-trimecaine alkyl iodide derivatives under the cipher BIV (BIV-117, BIV-118, and BIV-119) was conducted on a model of doxorubicin pancytopenia in white laboratory rats. It was established that the compounds BIV-117 and BIV-119 had a pronounced leukopoiesis-stimula...

journal_title：BioMed research international

authors： Baktybayeva L,Yu V,Zazybin A,Zolotareva D,Dauletbakov A

更新日期：2020-01-13 00:00:00

abstract：:Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases an...

journal_title：BioMed research international

authors： Ponomarenko P,Rasskazov D,Suslov V,Sharypova E,Savinkova L,Podkolodnaya O,Podkolodny NL,Tverdokhleb NN,Chadaeva I,Ponomarenko M,Kolchanov N

更新日期：2016-01-01 00:00:00

abstract：:Abnormal metabolism is another cancer hallmark. The two most characterized altered metabolic pathways are high rates of glycolysis and glutaminolysis, which are natural targets for cancer therapy. Currently, a number of newer compounds to block glycolysis and glutaminolysis are being developed; nevertheless, lonidamin...

journal_title：BioMed research international

authors： Cervantes-Madrid D,Romero Y,Dueñas-González A

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Fever in systemic lupus erythematosus (SLE) can be caused by infection or flare-up of the disease. This study aimed to determine whether the ratio of the level of erythrocyte-bound C4d to that of complement receptor 1 (C4d/CR1) can serve as a useful biomarker in the differentiation between infection and flare...

journal_title：BioMed research international

authors： Chen CH,Tai SB,Chen HC,Yang DH,Peng MY,Lin YF

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To quantitatively measure changes in cerebral perfusion in select regions of interest in the brain during urinary urgency in women with overactive bladder (OAB) using arterial spin labeling (ASL). METHODS:Twelve women with OAB and 10 controls underwent bladder filling and rated urinary urgency (scale 0-10). AS...

journal_title：BioMed research international

authors： Arya NG,Weissbart SJ,Xu S,Bhavsar R,Rao H

更新日期：2017-01-01 00:00:00

abstract：:Introduction. Second-line antituberculosis drugs (SLDs) are used for treating multidrug-resistant tuberculosis (MDR-TB). Prolonged delays before confirming MDR-TB with drug susceptibility testing (DST) could result in transmission of drug-resistant strains and inappropriate use of SLDs, thereby increasing the risk of ...

journal_title：BioMed research international

authors： Chen Y,Yuan Z,Shen X,Wu J,Wu Z,Xu B

更新日期：2016-01-01 00:00:00

abstract：:Curcumin is a bright yellow compound found in Curcuma longa L., a member of the family Zingiberaceae. In the present study, we determined whether curcumin protects against oxidative stress in liver and brain in mice fed excessive alcohol. BALB/c mice were administered 20% alcohol (16 g/kg body weight) with or without ...

journal_title：BioMed research international

authors： Pyun CW,Han KH,Hong GE,Lee CH

更新日期：2013-01-01 00:00:00

abstract：:Nematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for de...

journal_title：BioMed research international

authors： Ferreira SR,Mendes TA,Bueno LL,de Araújo JV,Bartholomeu DC,Fujiwara RT

更新日期：2015-01-01 00:00:00

abstract：Background:Spinal cord injury (SCI) is often associated with long-term impairments related to functional limitations in the sensorimotor system. The use of virtual reality (VR) technology may lead to increased motivation and engagement, besides allowing a wide range of possible tasks/exercises to be implemented in reha...

journal_title：BioMed research international

authors： de Araújo AVL,Neiva JFO,Monteiro CBM,Magalhães FH

更新日期：2019-11-13 00:00:00

abstract：OBJECTIVE:Identification of the factors that influence sedentary behaviour in older adults is important for the design of appropriate intervention strategies. In this study, we determined the prevalence of sedentary behaviour and its association with physical, cognitive, and psychosocial status among older adults resid...

journal_title：BioMed research international

authors： Leung PM,Ejupi A,van Schooten KS,Aziz O,Feldman F,Mackey DC,Ashe MC,Robinovitch SN

更新日期：2017-01-01 00:00:00

abstract：:Cancer is known to have unique metabolic features such as Warburg effect. Current cancer therapy has moved forward from cytotoxic treatment to personalized, targeted therapies, with some that could lead to specific metabolic changes, potentially monitored by imaging methods. In this paper we addressed the important as...

journal_title：BioMed research international

authors： Lin G,Chung YL

更新日期：2014-01-01 00:00:00