A Prospective Noninterventional, Observational Study to Describe the Effectiveness and Safety of Trandolapril and Verapamil Single-Pill Combination in the Management of Patients with Hypertension and Type 2 Diabetes Mellitus: A Harvest TR Study.

abstract：:Bacterial quorum sensing (QS) is a cell-to-cell communication in which specific signals are activated to coordinate pathogenic behaviors and help bacteria acclimatize to the disadvantages. The QS signals in the bacteria mainly consist of acyl-homoserine lactone, autoinducing peptide, and autoinducer-2. QS signaling ac...

journal_title：BioMed research international

authors： Jiang Q,Chen J,Yang C,Yin Y,Yao K

更新日期：2019-04-04 00:00:00

abstract：BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...

journal_title：BioMed research international

authors： Deylam Salehi M,Ferdosi-Shahandashti E,Yahyapour Y,Khafri S,Pournajaf A,Rajabnia R

更新日期：2017-01-01 00:00:00

abstract：:Here we aimed to develop a capillary electrophoresis-based high-throughput multiplex polymerase chain reaction (PCR) system for the simultaneous detection of nine pathogens in swine. Nine pairs of specific primers and a set of universal primers were designed; the multiplex PCR was established. The specificity and cros...

journal_title：BioMed research international

authors： Wu XL,Xiao L,Lin H,Yang M,Chen SJ,An W,Wang Y,Yao XP,Yang ZX,Tang ZZ

更新日期：2017-01-01 00:00:00

abstract：:Although considerable progress has been made in the management of patients with invasive fungal infections, Candida bloodstream infections are still widespread in hospital settings. Incidence rates vary geographically, often because of different patient populations. The aim of the present study was to describe the epi...

journal_title：BioMed research international

authors： Caggiano G,Coretti C,Bartolomeo N,Lovero G,De Giglio O,Montagna MT

更新日期：2015-01-01 00:00:00

abstract：:Candida krusei is osmotolerant yeast used for the production of glycerol. Addition of osmolyte such as NaCl into culture medium can increase the production of glycerol from glucose, but osmolytes may burden the glycerol separation. A coencapsulation method was suggested to create local extracellular hyperosmotic stres...

journal_title：BioMed research international

authors： Chen G,Yao S

更新日期：2013-01-01 00:00:00

abstract：:There has been a remarkable interest in finding lipid inhibitors from natural products to replace synthetic compounds, and a variety of oriental medicinal herbs are reported to have biological activity with regard to lipid inhibition. Buginawa (Bugi) is a novel combined formula that contains twelve medicinal herbs wit...

journal_title：BioMed research international

authors： Park YJ,Seo DW,Ju JY,Cha YY,An HJ

更新日期：2019-07-30 00:00:00

abstract：:Diabetic patients are at risk for spontaneous foot ulcers, chronic wounds, infections, and tissue necrosis. Current theories suggest that the development and progression of diabetic foot ulcers are mainly caused by arteriosclerosis and peripheral neuropathy. Tissue necrosis plays a primordial role in the progression o...

journal_title：BioMed research international

authors： Lévigne D,Tobalem M,Modarressi A,Pittet-Cuénod B

更新日期：2013-01-01 00:00:00

abstract：Objective:Epidemiological studies have shown a correlation between periodontal disease (PD) and age-related macular degeneration (AMD). However, the results have been inconsistent, and no relevant meta-analysis has been performed on this topic. Hence, we performed a meta-analysis to evaluate whether the two diseases ar...

journal_title：BioMed research international

authors： Lv X,Li W,Fang Z,Xue X,Pan C

更新日期：2020-09-28 00:00:00

abstract：:Mental rotation task (MRT) incorporates elements of spatial abilities, important in many professions, with people of both genders involved. Importantly, these are the areas where spatial tasks might be performed for long time periods; thus adverse effects of mental fatigue are highly unwanted. Substantial variation of...

journal_title：BioMed research international

authors： Noreika D,Griškova-Bulanova I,Alaburda A,Baranauskas M,Grikšienė R

更新日期：2014-01-01 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the dise...

journal_title：BioMed research international

authors： Choi J,Kook MS

更新日期：2015-01-01 00:00:00

abstract：:Tumourigenesis is a mutation accumulation process, which is likely to start with a mutated founder cell. The evolutionary nature of tumor development makes phylogenetic models suitable for inferring tumor evolution through genetic variation data. Copy number variation (CNV) is the major genetic marker of the genome wi...

journal_title：BioMed research international

authors： Liang Y,Liao B,Zhu W

更新日期：2017-01-01 00:00:00

abstract：Purpose:We evaluated the efficacies of the adaptive steepest descent projection onto convex sets (ASD-POCS), simultaneous algebraic reconstruction technique (SART), filtered back projection (FBP), and maximum likelihood expectation maximization (MLEM) total variation minimization iterative algorithms for reducing expos...

journal_title：BioMed research international

authors： Gomi T,Koibuchi Y

更新日期：2018-06-19 00:00:00

abstract：:In a retrospective study the association of the production of extracellular DNA (eDNA) in biofilms of clinical staphylococcal isolates from 60 patients with prosthetic joint infection (PJI) and the clinical outcome were investigated. Data from a previous study on eDNA production determined in 24-hour biofilms of staph...

journal_title：BioMed research international

authors： Zatorska B,Arciola CR,Haffner N,Segagni Lusignani L,Presterl E,Diab-Elschahawi M

更新日期：2018-10-22 00:00:00

abstract：:Mortierella sp. has been known to produce polyunsaturated fatty acids (PUFAs) such as GLA and AA under normal growth medium conditions. Similarly, under the stress condition, this fungus produces EPA and DHA in their mycelial biomass. Among the 67 soil samples screened from the Western Ghats of India, 11 Mortierella i...

journal_title：BioMed research international

authors： Vadivelan G,Venkateswaran G

更新日期：2014-01-01 00:00:00

abstract：:In this paper, a novel small-molecular apoptotic PET imaging probe, (18)F-ML-8 with a malonate motif structure, is presented and discussed. After study, the small tracer that belongs to a member of ApoSense family is proved to be capable of imaging merely apoptotic regions in the CTX treated tumor-bearing mice. The ex...

journal_title：BioMed research international

authors： Yao S,Hu K,Tang G,Gao S,Tang C,Yao B,Nie D,Sun T,Jiang S

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To distinguish between normal (SV-HUC-1) and cancerous (TCCSUP) human urothelial cell lines using microelectrical impedance spectroscopy (μEIS). MATERIALS AND METHODS:Two types of μEIS devices were designed and used in combination to measure the impedance of SV-HUC-1 and TCCSUP cells flowing through the channe...

journal_title：BioMed research international

authors： Park Y,Kim HW,Yun J,Seo S,Park CJ,Lee JZ,Lee JH

更新日期：2016-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder caused by selective loss of dopaminergic neurons in the substantia nigra pars compacta which leads to dysfunction of cerebral pathways critical for the control of movements. The diagnosis of PD is based on motor symptoms, such as bradykinesia, akinesia, muscular...

journal_title：BioMed research international

authors： Ciurleo R,Di Lorenzo G,Bramanti P,Marino S

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs and polymorphisms in ...

journal_title：BioMed research international

authors： García-Bermúdez M,López-Mejías R,Genre F,Castañeda S,Corrales A,Llorca J,González-Juanatey C,Ubilla B,Miranda-Filloy JA,Pina T,Gómez-Vaquero C,Rodríguez-Rodríguez L,Fernández-Gutiérrez B,Balsa A,Pascual-Salcedo D,López-Long

更新日期：2015-01-01 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Maternal thyroid dysfunction in early pregnancy may increase the risk of adverse pregnancy complications and neurocognitive deficiencies in the developing fetus. Currently, some researchers demonstrated that body mass index (BMI) is associated with thyroid function in nonpregnant population. Hence, the Ameri...

journal_title：BioMed research international

authors： Han C,Li C,Mao J,Wang W,Xie X,Zhou W,Li C,Xu B,Bi L,Meng T,Du J,Zhang S,Gao Z,Zhang X,Yang L,Fan C,Teng W,Shan Z

更新日期：2015-01-01 00:00:00

abstract：:The present study deals with the enzymatic synthesis of biodiesel by transesterification of Jatropha oil (Jatropha curcas L.) with ethanol in a solvent-free system. Seven commercial lipase preparations immobilized by covalent attachment on epoxy-polysiloxane-polyvinyl alcohol composite (epoxy-SiO2-PVA) were tested as ...

journal_title：BioMed research international

authors： Souza LT,Mendes AA,de Castro HF

更新日期：2016-01-01 00:00:00

abstract：:Beta-1,3-glucanosyltransferase (Gas1p) plays important roles in cell wall biosynthesis and morphogenesis and has been implicated in DNA damage responses and cell cycle regulation in fungi. Yeast Gas1p has also been reported to participate in endoplasmic reticulum (ER) stress responses. However, the precise roles and m...

journal_title：BioMed research international

authors： Cui HJ,Cui XG,Jing X,Yuan Y,Chen YQ,Sun YX,Zhao W,Liu XG

更新日期：2019-06-02 00:00:00

abstract：BACKGROUND:The aims of this study were to evaluate the complications that occur after trauma and the characteristics of individuals who develop complications, to identify potential risk factors that increase their incidence, and finally to investigate the relationship between complications and mortality. METHODS:We di...

journal_title：BioMed research international

authors： Mondello S,Cantrell A,Italiano D,Fodale V,Mondello P,Ang D

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to develop a vitrification procedure for human ovarian tissue cryopreservation in order to better preserve the ovarian tissue. Large size samples of ovarian tissue retrieved from 15 female-to-male transgender subjects (18-38 years) were vitrified using two solutions (containing propylene glyc...

journal_title：BioMed research international

authors： Fabbri R,Vicenti R,Macciocca M,Pasquinelli G,Paradisi R,Battaglia C,Martino NA,Venturoli S

更新日期：2014-01-01 00:00:00

abstract：:There has been no previous study using three-dimensional (3D) measurement on femoral tunnel characteristics according to the combined influence of various flexion angles of knee and transverse drill angles in single-bundle ACL reconstruction with transportal technique. The purpose of this study was to determine optima...

journal_title：BioMed research international

authors： Kim SH,Kim SJ,Choi CH,Kim D,Jung M

更新日期：2018-07-17 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：:Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

journal_title：BioMed research international

authors： Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

更新日期：2020-01-23 00:00:00

abstract：AIM:To evaluate the impact of SPARC on female sexual function. METHODS:151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. A minim...

journal_title：BioMed research international

authors： Al-Ali BM,Shamloul R,Hutterer GC,Puchwein E,Pummer K,Avian A,Primus G

更新日期：2013-01-01 00:00:00

abstract：:Background. The aim of this study was to assess the effects of low concentrations of H2O2 on angiogenesis of human umbilical vein endothelial cells (HUVECs) in vitro and explore the underlying mechanisms. Methods. HUVECs were cultured and stimulated with different concentrations of H2O2. Flow cytometric analysis was u...

journal_title：BioMed research international

authors： Jiang S,Zhang D,Huang H,Lei Y,Han Y,Han W

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To determine the histopathological differences after varicocele repair in testicular tissue in males with nonobstructive azoospermia. METHODS:Between 2009 and 2014, 45 men with complete azoospermia and palpable varicocele, presenting with primary infertility of at least 1 year, undergoing varicocele repair a...

journal_title：BioMed research international

authors： Ustuner M,Yilmaz H,Yavuz U,Ciftci S,Saribacak A,Aynur BS,Yasar H,Culha MM

更新日期：2015-01-01 00:00:00