Production and enhancement of omega-3 fatty acid from Mortierella alpina CFR-GV15: its food and therapeutic application.

abstract：Purpose:Accumulated evidence suggests that reproductive factors are related to different breast cancer subtypes, but most studies on these relationships are mainly focused on middle-aged and older patients, and it remains unclear how reproductive factors impact different subtypes of breast cancer in young women. Metho...

journal_title：BioMed research international

authors： Wang JM,Wang J,Zhao HG,Liu TT,Wang FY

更新日期：2020-04-06 00:00:00

abstract：:The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mes...

journal_title：BioMed research international

authors： Zanetti BF,Gomes WJ,Han SW

更新日期：2013-01-01 00:00:00

abstract：Background:Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. Methods:Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the hepatocellular apoptosi...

journal_title：BioMed research international

authors： Deng M,Wang J,Wu H,Wang M,Cao D,Li J,Wu Y,Gong J

更新日期：2020-03-18 00:00:00

abstract：:The immune system is regulated by distinct signaling pathways that control the development and function of the immune cells. Accumulating evidence suggest that ligation of aryl hydrocarbon receptor (Ahr), an environmentally responsive transcription factor, results in multiple cross talks that are capable of modulating...

journal_title：BioMed research international

authors： Hanieh H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and...

journal_title：BioMed research international

authors： Suwa M,Yamaguchi S,Komori T,Kajimoto S,Kino M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pu...

journal_title：BioMed research international

authors： Byeon HK,Han JH,Choi BI,Hwang HJ,Kim JH,Choi HS

更新日期：2015-01-01 00:00:00

abstract：:Newcastle disease (ND) is one of the most devastating diseases that considerably cripple the global poultry industry. Because of its enormous socioeconomic importance and potential to rapidly spread to naïve birds in the vicinity, ND is included among the list of avian diseases that must be notified to the OIE immedia...

journal_title：BioMed research international

authors： Bello MB,Yusoff K,Ideris A,Hair-Bejo M,Peeters BPH,Omar AR

更新日期：2018-08-05 00:00:00

abstract：BACKGROUND:Inflammation has a key role in migraine pathophysiology. Vitamin D is an effective anti-inflammatory agent. The aim of this study was to investigate the association between migraine and two vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and also the relationship between VDR polymorphisms and headache...

journal_title：BioMed research international

authors： Motaghi M,Haghjooy Javanmard S,Haghdoost F,Tajadini M,Saadatnia M,Rafiee L,Zandifar A

更新日期：2013-01-01 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：Purpose:Fractures are common among all types of paediatric injuries, with differences in incidence over time. Here, we present the epidemiologic features of traumatic fractures in a population of youth ≤ 18 years of age who were admitted to our university-affiliated hospitals from 2002 to 2010. Methods:We retrospectiv...

journal_title：BioMed research international

authors： Wang H,Feng C,Liu H,Liu J,Ou L,Yu H,Xiang L

更新日期：2019-02-20 00:00:00

abstract：:Adult orthodontics may confront problems related to the bonding performance of orthodontic brackets to new generation restorative materials used for crown or laminate restorations. The aim of the present study was to investigate the shear bond strength of ceramic brackets to two new generation CAD/CAM interpenetrating...

journal_title：BioMed research international

authors： Özarslan MM,Üstün Ö,Buyukkaplan US,Barutcigil Ç,Türker N,Barutcigil K

更新日期：2018-05-30 00:00:00

abstract：Objective:This study evaluated the bioactivity and physicochemical properties of three commercial calcium silicate-based endodontic materials (MTA, EndoSequence Root Repair Material putty, and Biodentine™). Material and Methods. Horizontal sections of 3 mm thickness from 18 root canals of human teeth were subjected to ...

journal_title：BioMed research international

authors： Talabani RM,Garib BT,Masaeli R

更新日期：2020-05-22 00:00:00

abstract：:An excessive pulmonary inflammatory response could explain the poor prognosis of chronic obstructive pulmonary disease (COPD) patients submitted to invasive mechanical ventilation. The aim of this study was to evaluate the response to normal tidal volume mechanical ventilation in an elastase-induced murine model of pu...

journal_title：BioMed research international

authors： Rouze A,Voiriot G,Guivarch E,Roux F,Tran Van Nhieu J,Isabey D,Brochard L,Maitre B,Mekontso-Dessap A,Boczkowski J

更新日期：2018-12-19 00:00:00

abstract：:Polyphenolic compounds are plant nutraceuticals showing a huge structural diversity, including chlorogenic acids, hydrolyzable tannins, and flavonoids (flavonols, flavanones, flavan-3-ols, anthocyanidins, isoflavones, and flavones). Most of them occur as glycosylated derivatives in plants and foods. In order to become...

journal_title：BioMed research international

authors： Marín L,Miguélez EM,Villar CJ,Lombó F

更新日期：2015-01-01 00:00:00

abstract：:Peroxisome proliferators-activated receptor (PPAR) gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63...

journal_title：BioMed research international

authors： Zhou T,Yan X,Wang G,Liu H,Gan X,Zhang T,Wang J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Acetabular fractures involving predominantly the anterior column associated with a disruption of the quadrilateral surface can be treated with instrumentation implementing the stabilization of the quadrilateral surface. The recently introduced suprapectineal quadrilateral buttress plate is specifically designed to pre...

journal_title：BioMed research international

authors： Egli RJ,Keel MJB,Cullmann JL,Bastian JD

更新日期：2017-01-01 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...

journal_title：BioMed research international

authors： Ivanova EA,Orekhov AN

更新日期：2015-01-01 00:00:00

abstract：:Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and expression of ICAM-1 mRNA in cells of the monocyte/macrophage system...

journal_title：BioMed research international

authors： Paulsen K,Tauber S,Dumrese C,Bradacs G,Simmet DM,Gölz N,Hauschild S,Raig C,Engeli S,Gutewort A,Hürlimann E,Biskup J,Unverdorben F,Rieder G,Hofmänner D,Mutschler L,Krammer S,Buttron I,Philpot C,Huge A,Lier H,Barz

更新日期：2015-01-01 00:00:00

abstract：:Colorectal cancer, a malignant neoplasm that occurs in the colorectal mucosa, is one of the most common types of gastrointestinal cancer. Colorectal cancer has been studied extensively, but the molecular mechanisms of this malignancy have not been characterized. This study identified and verified core genes associated...

journal_title：BioMed research international

authors： Xu H,Ma Y,Zhang J,Gu J,Jing X,Lu S,Fu S,Huo J

更新日期：2020-05-08 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...

journal_title：BioMed research international

authors： Chen S,Li H,Zhang J,Jiang S,Zhang M,Xu Y,Dong K,Yang Y,Fang Q,Jia W

更新日期：2017-01-01 00:00:00

abstract：Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...

journal_title：BioMed research international

authors： Nie H,Hu Y,Guo W,Wang W,Yang Q,Dong Q,Tang Y,Li Q,Tang Z

更新日期：2020-06-07 00:00:00

abstract：:Growing evidence suggests that increased arginase activity affects vital bioprocesses in various systems and universally mediates the pathogenesis of numerous metabolic diseases. The adverse effects of arginase are associated with a severe decline in L-arginine bioavailability, which leads to nitric oxide synthase sub...

journal_title：BioMed research international

authors： Gilinsky MA,Polityko YK,Markel AL,Latysheva TV,Samson AO,Polis B,Naumenko SE

更新日期：2020-02-12 00:00:00

abstract：:The objective of this study was the synthesis of folic acid- (FA-) targeted polymeric micelles of Synperonic PE/F 127-cholesteryl hemisuccinate (PF127-Chol) for specific delivery of docetaxel (DTX). Targeted or nontargeted micelles loaded with DTX were prepared via dialysis method. The effects of processing variables ...

journal_title：BioMed research international

authors： Varshosaz J,Taymouri S,Hassanzadeh F,Javanmard SH,Rostami M

更新日期：2015-01-01 00:00:00

abstract：Objective:ANGPTL7 is a member of the angiogenin-like protein family. Compared to other members, ANGPTL7 is the least known. Recent studies have explored the relationship between ANGPTL7 and multiple pathological processes and diseases. However, there is no research about ANGPTL7 in neonates. This study was designed to ...

journal_title：BioMed research international

authors： Xia X,Ren Z,Yan L,Zheng X,Yang H,Kang M,Yan H,Zhong Z,Xu F,Miao J,Wang J,Li Y,Wei W,Yang J

更新日期：2020-11-27 00:00:00

abstract：PURPOSE:To quantitatively measure changes in cerebral perfusion in select regions of interest in the brain during urinary urgency in women with overactive bladder (OAB) using arterial spin labeling (ASL). METHODS:Twelve women with OAB and 10 controls underwent bladder filling and rated urinary urgency (scale 0-10). AS...

journal_title：BioMed research international

authors： Arya NG,Weissbart SJ,Xu S,Bhavsar R,Rao H

更新日期：2017-01-01 00:00:00

abstract：:This research assessed the seasonal variation of the chemical composition and antibacterial and anticholinesterase activities of essential oils extracted from M. longifolia leaves. The leaves organic fractions were also investigated for their biological activities and pharmacological functions. The essential oil highe...

journal_title：BioMed research international

authors： Zouari-Bouassida K,Trigui M,Makni S,Jlaiel L,Tounsi S

更新日期：2018-12-09 00:00:00

abstract：:The research was performed on male Wistar rats based on assumptions that new microelement preparations containing metal nanoparticles and their agglomerates had potential. Morphological and functional changes in tissues in the injection site and dynamics of chemical element metabolism (25 indicators) in body were asse...

journal_title：BioMed research international

authors： Sizova E,Miroshnikov S,Yausheva E,Polyakova V

更新日期：2015-01-01 00:00:00

abstract：:A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...

journal_title：BioMed research international

authors： Rong E,Wang H,Hao S,Fu Y,Ma Y,Wang T

更新日期：2018-11-13 00:00:00

abstract：:The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...

journal_title：BioMed research international

authors： Moradell A,Gómez-Cabello A,Gómez-Bruton A,Muniz-Pardos B,Puyalto JM,Matute-Llorente A,Gónzalez-Agüero A,Ara I,Casajús JA,Vicente-Rodríguez G

更新日期：2020-07-15 00:00:00