Varicocele Repair Improves Testicular Histology in Men with Nonobstructive Azoospermia.

abstract：:Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. ...

journal_title：BioMed research international

authors： Liang B,He X,Zhao YX,Zhang XX,Gu N

更新日期：2020-07-07 00:00:00

abstract：:The role of nitric oxide and its reactive derivatives (NO x ) is well known in the pathogenesis of multiple sclerosis, which is an inflammatory disease while NO x seems to be important in coordinating inflammatory response. The...

journal_title：BioMed research international

authors： Niedziela N,Adamczyk-Sowa M,Niedziela JT,Mazur B,Kluczewska E,Sowa P,Gąsior M

更新日期：2016-01-01 00:00:00

abstract：:5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...

journal_title：BioMed research international

authors： Zhu Y,Xu L,Fan Y,Li C,Zhang Y,Zheng H,Hou K,Qu X,Liu Y

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Long-term survival of total knee arthroplasty (TKA) is mainly determined by optimal positioning of the components and prosthesis alignment. Implant positioning can be optimized by computer assisted surgery (CAS). Patient specific cutting blocks (PSCB) seem to have the potential to improve component alignment...

journal_title：BioMed research international

authors： Helmy N,Dao Trong ML,Kühnel SP

更新日期：2014-01-01 00:00:00

abstract：:Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage display peptide li...

journal_title：BioMed research international

authors： Song LJ,Li JH,Yin XR,Zhang W,Jin Y,Gao H,Wang J,Yu CX,Hua ZC

更新日期：2018-06-05 00:00:00

abstract：:Mild cognitive impairment (MCI) refers to a transitional state between normal aging and dementia and is a syndrome with cognitive decline greater than expected for an individual's age and educational level. As a subtype of MCI, amnestic mild cognitive impairment (aMCI) most often leads to Alzheimer's disease. This stu...

journal_title：BioMed research international

authors： Zhao Z,Lu J,Jia X,Chao W,Han Y,Jia J,Li K

更新日期：2014-01-01 00:00:00

abstract：:The insula is believed to be associated with touch-evoked effects. In this work, functional MRI was applied to investigate the network model of insula function when 20 normal subjects received tactile stimulation over segregated areas. Data analysis was performed with SPM8 and Conn toolbox. Activations in the contrala...

journal_title：BioMed research international

authors： Wei P,Bao R

更新日期：2013-01-01 00:00:00

abstract：:A reliable in vivo imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. Most stem cell transplantation studies have used immunohistological staining, which does not provide information about the migration of transplanted cells in vivo in the...

journal_title：BioMed research international

authors： Kim JH,Lee HJ,Song YS

更新日期：2015-01-01 00:00:00

abstract：:Sericin is a natural protein component of silks of silkworm and has potential utility in multiple areas such as pharmacological, cosmetics, and biotechnological industries. However, the understanding of its toxicological safety is still limited. This study evaluated the safety of water-extract sericin from silkworm (B...

journal_title：BioMed research international

authors： Qin H,Zhang J,Yang H,Yao S,He L,Liang H,Wang Y,Chen H,Zhao P,Qin G

更新日期：2020-11-05 00:00:00

abstract：:WHO reported that adherence among patients with chronic diseases averages only 50% in developed countries. This is recognized as a significant public health issue, since medication nonadherence leads to poor health outcomes and increased healthcare costs. Improving medication adherence is, therefore, crucial and revea...

journal_title：BioMed research international

authors： Lam WY,Fresco P

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/5901962.]. ...

journal_title：BioMed research international

authors： Hsu CC,Ko JY,Lin CL,Hsu HC,Chen HT,Lin CC,Kuo SJ

更新日期：2020-06-22 00:00:00

abstract：OBJECTIVE:There is a paucity of a biological large animal model of myocardial infarction (MI). We hypothesized that, using autologous-aggregated platelets, we could create an ovine model that was reproducible and more closely mimicked the pathophysiology of MI. METHODS:Mepacrine stained autologous platelets from male ...

journal_title：BioMed research international

authors： Spata T,Bobek D,Whitson BA,Parthasarathy S,Mohler PJ,Higgins RS,Kilic A

更新日期：2013-01-01 00:00:00

abstract：Background:In peritoneal dialysis (PD) patients, whether angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) could protect residual renal function is still controversial. To assess the effects of ACEIs and ARBs on the residual renal function and cardiovascular (CV) events in perito...

journal_title：BioMed research international

authors： Ding L,Yang J,Li L,Yang Y

更新日期：2020-09-23 00:00:00

abstract：Purpose:Triple-negative breast cancer refers to breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (Her2). This study aimed to identify the key pathways and genes and find the potential initiation and progression mechanism of triple-negati...

journal_title：BioMed research international

authors： Dong P,Yu B,Pan L,Tian X,Liu F

更新日期：2018-08-02 00:00:00

abstract：:Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, ge...

journal_title：BioMed research international

authors： Abdullah Al-Dhabi N,Srigopalram S,Ilavenil S,Kim YO,Agastian P,Baaru R,Balamurugan K,Choi KC,Valan Arasu M

更新日期：2016-01-01 00:00:00

abstract：:Vitamin D is important for normal development and maintenance of the skeleton. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity, matrix ossification, bone remodeling and bone density. It is well known that Vit. D deficiency in the developing skeleton is related to rickets, while in adults ...

journal_title：BioMed research international

authors： Christodoulou S,Goula T,Ververidis A,Drosos G

更新日期：2013-01-01 00:00:00

abstract：:Cervical cancer is one of the malignant tumors that seriously threaten women's health. The mechanism of development needs to be deeply studied. In recent years, lncRNA has been identified as one of the important factors affecting the malignant progression of tumors. In this study, we illustrated the important mechanis...

journal_title：BioMed research international

authors： Hu T,Zhang Q,Gao L

更新日期：2020-01-03 00:00:00

abstract：PURPOSE:To quantitatively measure changes in cerebral perfusion in select regions of interest in the brain during urinary urgency in women with overactive bladder (OAB) using arterial spin labeling (ASL). METHODS:Twelve women with OAB and 10 controls underwent bladder filling and rated urinary urgency (scale 0-10). AS...

journal_title：BioMed research international

authors： Arya NG,Weissbart SJ,Xu S,Bhavsar R,Rao H

更新日期：2017-01-01 00:00:00

abstract：Introduction:To identify and analyze factors that influence administration, recognition, and compliance of medicine among community residents in Jilin Province, China. Methods:A survey was carried out among 2417 community residents in Jilin Province, China, to study their administration (CRA), recognition (CRR), and c...

journal_title：BioMed research international

authors： Song YQ,Zhang WR,Zhang SX,Wang TH,Jiang Z,Meng CF,Zhang TZ,Xin QZ,Cao KJ,Zhang Y,Sun Y

更新日期：2020-07-18 00:00:00

abstract：:No pharmacological treatment is currently available to protect brain from neuronal damage after ischemic stroke. Recent studies found that enkephalin may play an important role in neuron regeneration. We assembled a homogeneous size vesicle constituted by transferrin, exosomes, and enkephalin. Immunofluorescence assay...

journal_title：BioMed research international

authors： Liu Y,Fu N,Su J,Wang X,Li X

更新日期：2019-03-04 00:00:00

abstract：:Adiponectin (APN) is an adipokine secreted from adipose tissue and exhibits biological functions such as microcirculation-regulating, hearing-protective, and antiapoptotic. However, the effect of APN on the apoptosis of spiral arterial smooth muscle cells (SMCs) under hypoxic conditions in vitro is not clear. We used ...

journal_title：BioMed research international

authors： Xiao J,Zhang Y,Zhang W,Zhang L,Li L,Si J,Li X,Ma K

更新日期：2020-10-10 00:00:00

abstract：PURPOSE:To evaluate the changes of keratocytes and dendritic cells in the central clear graft by laser scanning in vivo confocal microscopy after penetrating keratoplasty (PK). METHODS:Thirty adult subjects receiving PK at Shandong Eye Institute and with clear grafts and no sign of immune rejection after surgery were ...

journal_title：BioMed research international

authors： Wang D,Song P,Wang S,Sun D,Wang Y,Zhang Y,Gao H

更新日期：2016-01-01 00:00:00

abstract：:Apolipoprotein E4 (Apo E4) is the major genetic risk factor in the causation of Alzheimer's disease (AD). In this study we utilize virtual screening of the world's largest traditional Chinese medicine (TCM) database and investigate potential compounds for the inhibition of ApoE4. We present the top three TCM candidate...

journal_title：BioMed research international

authors： Huang HJ,Chen HY,Lee CC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...

journal_title：BioMed research international

authors： Białkowska J,Juranek J,Wojtkiewicz J

更新日期：2020-11-03 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6353510.]. ...

journal_title：BioMed research international

authors： Skjerdal T,Gefferth A,Spajic M,Estanga EG,De Cesare A,Vitali S,Pasquali F,Bovo F,Manfreda G,Mancusi R,Trevisiani M,Tessema GT,Fagereng T,Moen LH,Lyshaug L,Koidis A,Delgado-Pando G,Stratakos AC,Boeri M,From C,Syed

更新日期：2018-09-26 00:00:00

abstract：:In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...

journal_title：BioMed research international

authors： Rizzo L,Attanasio M,Pinzone MR,Berretta M,Malaguarnera M,Morra A,L'Abbate L,Balestreri L,Nunnari G,Cacopardo B

更新日期：2014-01-01 00:00:00

abstract：:Microbial strain optimisation for the overproduction of a desired phenotype has been a popular topic in recent years. Gene knockout is a genetic engineering technique that can modify the metabolism of microbial cells to obtain desirable phenotypes. Optimisation algorithms have been developed to identify the effects of...

journal_title：BioMed research international

authors： Choon YW,Mohamad MS,Deris S,Chong CK,Omatu S,Corchado JM

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the microtensile bond strength (μTBS) of 1-step self-etch adhesives (1-SEAs) and 2-step self-etch adhesives (2-SEAs) to pulp chamber dentin immediately after bleaching with 2 types of common bleaching techniques. Pulp chamber dentin of bovine teeth was bleached using 30% hydrogen peroxide (H2O2) s...

journal_title：BioMed research international

authors： Haruyama A,Kameyama A,Kato J,Takemoto S,Oda Y,Kawada E,Takahashi T,Furusawa M

更新日期：2016-01-01 00:00:00

abstract：:While the world is stepping into the aging society, rehabilitation robots play a more and more important role in terms of both rehabilitation treatment and nursing of the patients with neurological diseases. Benefiting from the abundant contents of movement information, electroencephalography (EEG) has become a promis...

journal_title：BioMed research international

authors： Zhang J,Wei J,Wang B,Hong J,Wang J

更新日期：2014-01-01 00:00:00

abstract：Results:The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (Dmax) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for Dmean of the heart and left ventricle ...

journal_title：BioMed research international

authors： Hu J,Han G,Lei Y,Xu X,Ge W,Ruan C,Chang S,Zhang A,Li X

更新日期：2020-03-26 00:00:00