Identification of Key Genes and Pathways in Triple-Negative Breast Cancer by Integrated Bioinformatics Analysis.

abstract：:While the world is stepping into the aging society, rehabilitation robots play a more and more important role in terms of both rehabilitation treatment and nursing of the patients with neurological diseases. Benefiting from the abundant contents of movement information, electroencephalography (EEG) has become a promis...

journal_title：BioMed research international

authors： Zhang J,Wei J,Wang B,Hong J,Wang J

更新日期：2014-01-01 00:00:00

abstract：:Influences of environmental variables and emulsifiers on lipase production of a Candida viswanathii strain were investigated. The highest lipase activity (101.1 U) was observed at 210 rpm, pH 6.0, and 27.5°C. Other fermentation parameters analyzed showed considerable rates of biomass yield (Y L/S = 1.381 g/g), lipase ...

journal_title：BioMed research international

authors： de Almeida AF,Tauk-Tornisielo SM,Carmona EC

更新日期：2013-01-01 00:00:00

abstract：:We previously reported that Runx2/miR-3960/miR-2861 regulatory feedback loop stimulates osteoblast differentiation. However, the effect of this feedback loop on the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) remains unclear. Our recent study showed that miR-2861 and miR-3960 expression inc...

journal_title：BioMed research international

authors： Xia ZY,Hu Y,Xie PL,Tang SY,Luo XH,Liao EY,Chen F,Xie H

更新日期：2015-01-01 00:00:00

abstract：:This study investigated how the posture of the thumb while performing common pinch movements and the levels of pinch force applied by the thumb affect the arthrokinematics of the trapeziometacarpal joint in vivo. Fifteen subjects performed the pinch tasks at the distal phalange (DP), proximal interphalangeal (PIP) joi...

journal_title：BioMed research international

authors： Kuo LC,Lin CJ,Chen GP,Jou IM,Wang CK,Goryacheva IG,Dosaev MZ,Su FC

更新日期：2014-01-01 00:00:00

abstract：:Besides the pinpointing of individual disease-related genes, associating protein complexes to human inherited diseases is also of great importance, because a biological function usually arises from the cooperative behaviour of multiple proteins in a protein complex. Moreover, knowledge about disease-related protein co...

journal_title：BioMed research international

authors： Jacquemin T,Jiang R

更新日期：2013-01-01 00:00:00

abstract：:The normal physiological loads from muscles experienced by the spine are largely unknown due to a lack of data. The aim of this study is to investigate the effects of varying muscle directions on the outcomes predicted from finite element models of human lumbar spine. A nonlinear finite element model of L3-L5 was empl...

journal_title：BioMed research international

authors： Zhu R,Niu WX,Wang ZP,Pei XL,He B,Zeng ZL,Cheng LM

更新日期：2018-01-03 00:00:00

abstract：:Metastasis is the leading cause of lung cancer-associated death. Downregulated expression of E-cadherin followed by epithelial-mesenchymal transition (EMT) is critical for metastasis initiation in lung cancer. BTBD7 plays essential roles in lung cancer metastasis, but the mechanisms remain unknown. This study aimed to...

journal_title：BioMed research international

authors： Shu J,Wang L,Han F,Chen Y,Wang S,Luo F

更新日期：2019-11-27 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：:Platelets are anuclear cells and are devoid of genomic DNA, but they are capable of de novo protein synthesis from mRNA derived from their progenitor cells, megakaryocytes. There is mounting evidence that microRNA (miRNA) plays an important role in regulating gene expression in platelets. miR-223 is the most abundant ...

journal_title：BioMed research international

authors： Shi R,Zhou X,Ji WJ,Zhang YY,Ma YQ,Zhang JQ,Li YM

更新日期：2015-01-01 00:00:00

abstract：:D-Ribose is a five-carbon sugar and generally used as an energy source to improve athletic performance and the ability. The culture conditions for maximum D-ribose production performance from cheap raw material corn starch hydrolysate were improved by using one-factor-at-a-time experiments and a three-level Box-Behnke...

journal_title：BioMed research international

authors： Wei Z,Zhou J,Sun W,Cui F,Xu Q,Liu C

更新日期：2015-01-01 00:00:00

abstract：:Tyrosine kinase inhibitors (TKI) belong to a new class of molecular multitargeted anticancer therapy which targets different growth factor receptors and hence attenuates cancer cell survival and growth. Since their introduction as adjunct treatment for renal cell carcinoma and gastrointestinal stromal tumors (GIST), a...

journal_title：BioMed research international

authors： Ahmadieh H,Salti I

更新日期：2013-01-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...

journal_title：BioMed research international

authors： Lee S,Kim Y,Kwon MS,Park T

更新日期：2015-01-01 00:00:00

abstract：:Objectives. To investigate the potential association of a set of serum cytokines with the severity of coronary artery disease (CAD). Methods. A total of 201 patients who underwent coronary angiography for chest discomfort were enrolled. The concentrations of serum IFN-γ, TNF-α, IL-2, IL-4, IL-6, IL-10, IL-9, and IL-17...

journal_title：BioMed research international

authors： Min X,Lu M,Tu S,Wang X,Zhou C,Wang S,Pang S,Qian J,Ge Y,Guo Y,Xu D,Cao K

更新日期：2017-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full-fledged annotation systems are usually home-grown and customized to a particular geno...

journal_title：BioMed research international

authors： Alioto T,Picardi E,Guigó R,Pesole G

更新日期：2013-01-01 00:00:00

abstract：Background:The chromobox (CBX) proteins CBX2, CBX4, CBX6, CBX7, and CBX8, also known as Polycomb (Pc) proteins, are canonical components of the Polycomb repressive complex 1 (PRC1). Abundant evidence indicates that abnormal expression of Pc proteins is associated with a variety of tumors, but their role in the pathogen...

journal_title：BioMed research international

authors： Tan C,Bei C,Zhu X,Zhang Y,Qin L,Tan S

更新日期：2019-05-09 00:00:00

abstract：OBJECTIVE:To investigate the relationship of delivery type, maternal anesthesia, feeding modalities, and first feeding and meconium passage times with early bilirubin levels of healthy infants. METHODS:Cord, 24 hours' and 48 hours' total bilirubin levels were measured in 388 study infants. RESULTS:Infants born with c...

journal_title：BioMed research international

authors： Siyah Bilgin B,Altun Koroglu O,Yalaz M,Karaman S,Kultursay N

更新日期：2013-01-01 00:00:00

abstract：:A wide range of molecular techniques have been developed for genotyping Candida species. Among them, multilocus sequence typing (MLST) and microsatellite length polymorphisms (MLP) analysis have recently emerged. MLST relies on DNA sequences of internal regions of various independent housekeeping genes, while MLP iden...

journal_title：BioMed research international

authors： Spampinato C,Leonardi D

更新日期：2013-01-01 00:00:00

abstract：Aim:The aim of this study was to explore the correlation of chemokine receptor CXCR3 with M2 macrophage infiltration, various clinicopathological features, and prognosis in patients diagnosed with gastric cancer (GC). Methods:Expression of CXCR3 protein and M2 macrophage was evaluated in 156 GC patients and correspond...

journal_title：BioMed research international

authors： Chen F,Yuan J,Yan H,Liu H,Yin S

更新日期：2019-05-21 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:The purpose of the study is to evaluate the relationship between NIH-CPSI and IIEF-5 in Chinese men with CP/CPPS. A large cross-sectional and multicenter survey was conducted from July 2012 to January 2014. Men were recruited from urology clinics which were located at the five cities in China. All men participated in ...

journal_title：BioMed research international

authors： Gao J,Gao P,Hao Z,Zhou Z,Liu J,Li H,Xing J,Zhou Z,Deng C,Deng L,Wei Q,Zhang X,Zhou J,Fan S,Tai S,Yang C,Shi K,Huang Y,Ye Z,Liang C

更新日期：2015-01-01 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：Objective:Primary headache and obesity are highly prevalent disorders in the general population. Although many studies have reported an association between the two, there is still no overall comprehension about this relationship. To gain a more accurate understanding in this regard, we analyzed data from a 2011 cross-s...

journal_title：BioMed research international

authors： Huang Q,Yu H,Zhang N,Guo B,Feng C,Wang S,Liang X

更新日期：2019-04-15 00:00:00

abstract：:Exposure to dioxins, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is reported to affect the autoimmune system and increase the risk of autoimmune disease. Generally, dioxin exerts its toxicity via aryl hydrocarbon receptor (AhR). Primary biliary cholangitis (PBC) is a chronic autoimmune disease, and its pathoge...

journal_title：BioMed research international

authors： She C,Wang J,Tang N,Liu Z,Xu L,Liu B

更新日期：2020-08-24 00:00:00

abstract：:In renal cell carcinoma, chromophobe renal cell carcinoma (ChRCC) is a distinct subtype, whose clinical manifestations often lack specificity, and the molecular mechanisms of ChRCC tumorigenesis remain generally vague. The target of this study was to discover novel biomarkers involved in ChRCC by integrated bioinforma...

journal_title：BioMed research international

authors： Zhang W,Xu Y,Zhang J,Wu J

更新日期：2020-02-07 00:00:00

abstract：OBJECTIVES:CD57 is normally found on NK-cells, but little is known about its expression in prostatic tissue. METHODS:We investigated CD57 expression by immunohistochemistry using tissue microarrays containing 3262 prostate cancers (PCa), lymph node metastases, and benign prostatic tissue. The results were compared wit...

journal_title：BioMed research international

authors： Wangerin H,Kristiansen G,Schlomm T,Stephan C,Gunia S,Zimpfer A,Weichert W,Sauter G,Erbersdobler A

更新日期：2014-01-01 00:00:00

abstract：:In esophageal squamous cell carcinoma, an elevated preoperative absolute monocyte count (Pre-AMC) is reported to be a predictor of survival, but the clinical application of postoperative absolute monocyte count change (AMCc) remains unknown. The present study was designed to investigate the prognostic value of AMCc in...

journal_title：BioMed research international

authors： Song Q,Wu JZ,Wang S

更新日期：2019-08-14 00:00:00

abstract：INTRODUCTION:Previous studies have demonstrated the safety and efficacy of using Paricalcitol for the treatment of secondary hyperparathyroidism (SHPT) in patients on dialysis. The aim of the current meta-analysis was to assess the safety and efficacy of Paricalcitol for the management of SHPT in patients with chronic ...

journal_title：BioMed research international

authors： Han T,Rong G,Quan D,Shu Y,Liang Z,She N,Liu M,Yang B,Cheng G,Lv Y,Stern L

更新日期：2013-01-01 00:00:00

abstract：:Diabetic patients are at risk for spontaneous foot ulcers, chronic wounds, infections, and tissue necrosis. Current theories suggest that the development and progression of diabetic foot ulcers are mainly caused by arteriosclerosis and peripheral neuropathy. Tissue necrosis plays a primordial role in the progression o...

journal_title：BioMed research international

authors： Lévigne D,Tobalem M,Modarressi A,Pittet-Cuénod B

更新日期：2013-01-01 00:00:00

abstract：Objective:The aim of this study was to investigate the association between adiponectin gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 and environmental risk factors of type 2 diabetes mellitus (T2DM) in Hohhot. The study explored different models of gene-environment interactions, aimed at p...

journal_title：BioMed research international

authors： Cui M,Gao Y,Zhao Y,Pang H,Chen L,Wang Z,Zhao L,Li M

更新日期：2020-06-21 00:00:00