Single Nucleotide Polymorphisms of CBX4 and CBX7 Decrease the Risk of Hepatocellular Carcinoma.

abstract：:The microbial resistance of fungi and bacteria is currently considered a major public health problem. Esters derived from cinnamic acid have a broad spectrum of pharmacological properties that include antimicrobial activity. In this study, a collection of structurally related 4-chlorocinnamic acid esters was prepared ...

journal_title：BioMed research international

authors： Silva RHN,Andrade ACM,Nóbrega DF,de Castro RD,Pessôa HLF,Rani N,de Sousa DP

更新日期：2019-04-23 00:00:00

abstract：BACKGROUND:This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS:Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneou...

journal_title：BioMed research international

authors： Akashi M,Hashikawa K,Wanifuchi S,Kusumoto J,Shigeoka M,Furudoi S,Terashi H,Komori T

更新日期：2017-01-01 00:00:00

abstract：:The goal of the present study were (1) to investigate the pathological characteristics of gastrocnemius muscle (GM) and quantitatively assess GM tissue stiffness in rat models with spinal cord injury (SCI) and (2) to explore the correlation between pathological characteristics changes and Young's modulus value of GM. ...

journal_title：BioMed research international

authors： Jiang L,Wang YJ,Wang QY,Wang Q,Wei XM,Li N,Guo WP,Dou ZL

更新日期：2017-01-01 00:00:00

abstract：:Nematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for de...

journal_title：BioMed research international

authors： Ferreira SR,Mendes TA,Bueno LL,de Araújo JV,Bartholomeu DC,Fujiwara RT

更新日期：2015-01-01 00:00:00

abstract：:Rauwolfia tetraphylla L. is an important medicinal plant species which is well known for its pharmaceutically important alkaloids. In the present study, we are reporting about its conservation by in vitro clonal multiplication through the standardized protocol of indirect regeneration by using leaf and stem based call...

journal_title：BioMed research international

authors： Rohela GK,Jogam P,Bylla P,Reuben C

更新日期：2019-04-11 00:00:00

abstract：:In spite of the declining incidence of gastric cancer (GC) in recent years, the mortality rate is still high. The asymptomatic nature and nonspecific clinical manifestations combined with the lack of efficient screening programs delay the diagnosis of GC. Therefore, the prevalence of advanced gastric cancer (AGC) has ...

journal_title：BioMed research international

authors： Xu W,Beeharry MK,Liu W,Yan M,Zhu Z

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported in SAH, their origin remains unclear. The aim of this study was to report the detection of ES during routine TCD monitoring in patients with aneurysmal SAH. METHODS:...

journal_title：BioMed research international

authors： Paschoal FM Jr,de Almeida Lins Ronconi K,de Lima Oliveira M,Nogueira Rde C,Paschoal EH,Teixeira MJ,Figueiredo EG,Bor-Seng-Shu E

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Histones play important roles in both host defenses and inflammation related to microbial infection. A peptide mimotope (SSV) was identified from a novel histone H1 monoclonal antibody (16G9 mAb) that was shown to inhibit the mixed lymphocyte reaction. In the present study, an anti-SSV producing hybridoma wa...

journal_title：BioMed research international

authors： Kusano T,Chiang KC,Inomata M,Shimada Y,Ohmori N,Goto T,Sato S,Goto S,Nakano T,Kawamoto S,Takaoka Y,Shiraishi N,Noguchi T,Kitano S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:The sensitivity and specificity of biomarkers used for predicting peripheral neuropathy in patients with systemic lupus erythematosus (SLE) and nephritis (SLE-LN) remain unsatisfactory. This study aimed to determine the autoantibodies levels in SLE-LN patients with peripheral neuropathy. METHODS:Dat...

journal_title：BioMed research international

authors： Su YJ,Huang CR,Chang WN,Tsai NW,Kung CT,Lin WC,Huang CC,Su CM,Cheng BC,Chang YT,Lu CH

更新日期：2014-01-01 00:00:00

abstract：:Hitherto, limited clinical impact has been achieved in the treatment of glioblastoma (GBMs). Although phytochemicals found in medicinal herbs can provide mankind with new therapeutic remedies, single agent intervention has failed to bring the expected outcome in clinical trials. Therefore, combinations of several agen...

journal_title：BioMed research international

authors： Elkady AI,Hussein RA,Abu-Zinadah OA

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to describe the first metabolic profile of human sperm cells through the application of an untargeted platform based on gas chromatography-mass spectrometry (GC-MS). Sperm cell samples from patients diagnosed with idiopathic asthenozoospermia (n = 30) and healthy subjects (n = 30) were an...

journal_title：BioMed research international

authors： Zhao K,Zhang J,Xu Z,Xu Y,Xu A,Chen W,Miao C,Liu S,Wang Z,Jia R

更新日期：2018-02-28 00:00:00

abstract：:Several studies report that the OPG is an important candidate gene in the pathogenesis of osteoporosis. This study aimed to detect the potential association of OPG gene polymorphisms with osteoporosis in postmenopausal women. We recruited 928 subjects containing 463 with primary postmenopausal osteoporosis and 465 hea...

journal_title：BioMed research international

authors： Wang F,Cao Y,Li F,Shan J,Wen T

更新日期：2014-01-01 00:00:00

abstract：:Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The h...

journal_title：BioMed research international

authors： Lu J,Li Y,Hu D,Chen X,Liu Y,Wang L,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：:Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO antibody (monoclonal 72D9)...

journal_title：BioMed research international

authors： Matsubara E,Takamura A,Okamoto Y,Oono H,Nakata T,Wakasaya Y,Kawarabayashi T,Shoji M

更新日期：2013-01-01 00:00:00

abstract：:Subarachnoid hemorrhage (SAH) is a devastating neurological disorder. Patients with aneurysmal SAH develop secondary complications that are important causes of morbidity and mortality. Aside from secondary neurological injuries, SAH has been associated with nonneurologic medical complications, such as neurocardiogenic...

journal_title：BioMed research international

authors： Chen S,Li Q,Wu H,Krafft PR,Wang Z,Zhang JH

更新日期：2014-01-01 00:00:00

abstract：Aims:The purpose of this study was to describe the challenge of cross-cultural care encounters from perspective of imported nurses in Lhasa, Tibet, as well as investigate the relationship of cross-cultural care encounters and its influencing factors. Methods:A cross-sectional survey was designed among 300 imported nur...

journal_title：BioMed research international

authors： Bai M,Sui X,Zhou C,Li Y,Li J,Gao R,Du Z,Xu L,Li F

更新日期：2020-04-08 00:00:00

abstract：:Hydrogel injection has been recently proposed as a novel therapy for disc degenerative diseases, with the potential to restore the spine motion and the intervertebral disc height. However, it remains unknown whether the new technique could also maintain the shock absorbing property of the treated intervertebral disc. ...

journal_title：BioMed research international

authors： Zhou Z,Gao M,Wei F,Liang J,Deng W,Dai X,Zhou G,Zou X

更新日期：2014-01-01 00:00:00

abstract：:CA-125 has been a valuable marker for the follow-up of ovarian cancer patients but it is not sensitive enough to be used as diagnostic marker. We had already used secretomic methods to identify proteins differentially secreted by serous ovarian cancer cells compared to healthy ovarian cells. Here, we evaluated the sec...

journal_title：BioMed research international

authors： Kramer M,Pierredon S,Ribaux P,Tille JC,Petignat P,Cohen M

更新日期：2015-01-01 00:00:00

abstract：Purpose:To study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats. Methods:A high-fat diet (HF) was given to 28 rats and 28 ...

journal_title：BioMed research international

authors： Stygar D,Pigłowski W,Chełmecka E,Skrzep-Poloczek B,Sawczyn T,Garłowski W,Jochem J,Karcz KW

更新日期：2018-08-16 00:00:00

abstract：Background:Previous studies have investigated the association between the use of bisphosphonates and the development of breast cancer, which presented controversial results. Thus, this meta-analysis was conducted to summarize the current evidence of the association of bisphosphonate use with breast cancer risk. Method...

journal_title：BioMed research international

authors： Peng R,Liang X,Zhang G,Yao Y,Chen Z,Pan X,Wang J,Liu G

更新日期：2020-10-06 00:00:00

abstract：:Seeking new biomarkers for epithelial ovarian cancer, the fifth most common cause of death from all cancers in women and the leading cause of death from gynaecological malignancies, we performed a meta-analysis of three independent studies and compared the results in regard to clinicopathological parameters. This anal...

journal_title：BioMed research international

authors： Buehler M,Tse B,Leboucq A,Jacob F,Caduff R,Fink D,Goldstein DR,Heinzelmann-Schwarz V

更新日期：2013-01-01 00:00:00

abstract：:Progression of idiopathic dilated cardiomyopathy (IDCM) is marked with extensive left ventricular remodeling whose clinical manifestations and molecular basis are poorly understood. We aimed to evaluate the clinical potential of titin ligands in monitoring progression of cardiac remodeling associated with end-stage ID...

journal_title：BioMed research international

authors： Bogomolovas J,Brohm K,Čelutkienė J,Balčiūnaitė G,Bironaitė D,Bukelskienė V,Daunoravičus D,Witt CC,Fielitz J,Grabauskienė V,Labeit S

更新日期：2015-01-01 00:00:00

abstract：:Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-produ...

journal_title：BioMed research international

authors： Germinara GS,De Cristofaro A,Rotundo G

更新日期：2016-01-01 00:00:00

abstract：:Uterine fibroids (UFs) are benign tumors of the reproductive tract, arising from smooth muscle cells of the uterus. Steroid hormones, estrogen, and progesterone are considered to be the most important links in the pathophysiology of UFs. Alpha-tocopherol (AT) is the most active form of vitamin E. What is important as ...

journal_title：BioMed research international

authors： Ciebiera M,Szymańska-Majchrzak J,Sentkowska A,Kilian K,Rogulski Z,Nowicka G,Jakiel G,Tomaszewski P,Włodarczyk M

更新日期：2018-07-24 00:00:00

abstract：:Schistosomiasis is the most prevalent tropical disease in the world after malaria. According to the World Health Organization, the disease afflicts more than 240 million people in about 80 countries. Recently, an epidemiological surveillance study performed between 1997 and 2010 by the European Network for Tropical Me...

journal_title：BioMed research international

authors： Brindicci G,Santoro CR,De Laurentiis V,Capolongo C,Solarino ME,Papagni R,Ciracì E,Gatti P,Loconsole D,Monno R,Monno L,Miragliotta G,Angarano G

更新日期：2017-01-01 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; ...

journal_title：BioMed research international

authors： Mirsaeidi M,Farshidpour M,Allen MB,Ebrahimi G,Falkinham JO

更新日期：2014-01-01 00:00:00

abstract：Background and Aims:The value of hepatocyte regeneration in predicting the outcomes of hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) is not fully assessed. The present study was aimed at establishing a novel scoring system to predict patients' outcomes within 3 months by applying serological indicators ...

journal_title：BioMed research international

authors： Wang X,Sun M,Yang X,Gao L,Weng M,Yang D,Li H,Zhou X,Li J,Qin S,Zhou D,Wu X,Tang S,Zeng W

更新日期：2020-08-06 00:00:00

abstract：:Salinity is a major environmental stress that limits crop production worldwide. In this study, we characterized plant growth-promoting rhizobacteria (PGPR) containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase and examined their effect on salinity stress tolerance in okra through the induction of ROS-scavenging...

journal_title：BioMed research international

authors： Habib SH,Kausar H,Saud HM

更新日期：2016-01-01 00:00:00

abstract：:POZ/BTB domains are widespread modules detected in a variety of different biological contexts. Here, we report a biophysical characterization of the POZ/BTB of KCTD6, a protein that is involved in the turnover of the muscle small ankyrin-1 isoform 5 and, in combination with KCTD11, in the ubiquitination and degradatio...

journal_title：BioMed research international

authors： Pirone L,Esposito C,Correale S,Graziano G,Di Gaetano S,Vitagliano L,Pedone E

更新日期：2013-01-01 00:00:00

abstract：:Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...

journal_title：BioMed research international

authors： Haass NK,Nassif N,McGowan EM

更新日期：2015-01-01 00:00:00