Antimicrobial Activity of 4-Chlorocinnamic Acid Derivatives.

abstract：UNLABELLED:The aims of this study were first to clearly define two different entities: locoregional recurrences and limited metastatic disease and secondly to evaluate the place of extensive surgery in these two types of recurrence. MATERIAL AND METHODS:Twenty-four patients were followed from June 2004 until May 2014....

journal_title：BioMed research international

authors： Berlière M,Duhoux FP,Taburiaux L,Lacroix V,Galant C,Leconte I,Fellah L,Lecouvet F,Bouziane D,Piette P,Lengele B

更新日期：2015-01-01 00:00:00

abstract：Background:Thyroid cancer is the most common endocrine malignancy, with a recent global increase of 20% in age-related incidence. Ultrasonography and ultrasonography-guided fine-needle aspiration biopsy (FNAB) are the most widely used diagnostic tests for thyroid nodules; however, it is estimated that up to 25% of thyr...

journal_title：BioMed research international

authors： Nan BY,Xiong GF,Zhao ZR,Gu X,Huang XS

更新日期：2021-01-12 00:00:00

abstract：:The present study evaluated the anti-inflammatory and analgesic effects of the superoxide dismutase mimetic agent tempol in superoxide anion-induced pain and inflammation. Mice were treated intraperitoneally with tempol (10-100 mg/kg) 40 min before the intraplantar injection of a superoxide anion donor, potassium supe...

journal_title：BioMed research international

authors： Bernardy CCF,Zarpelon AC,Pinho-Ribeiro FA,Calixto-Campos C,Carvalho TT,Fattori V,Borghi SM,Casagrande R,Verri WA Jr

更新日期：2017-01-01 00:00:00

abstract：:Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3-step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the...

journal_title：BioMed research international

authors： Al-Qattan MM

更新日期：2019-09-15 00:00:00

abstract：:The effects of obstruction on renal function are the consequence of many factors that profoundly alter all components of glomerular function. Besides the acute effects on glomerular filtration rate and tubule function, a chronic obstruction induces tubular and interstitial injury that results from the activation of di...

journal_title：BioMed research international

authors： Lucarelli G,Mancini V,Galleggiante V,Rutigliano M,Vavallo A,Battaglia M,Ditonno P

更新日期：2014-01-01 00:00:00

abstract：:Presynaptic and postsynaptic neurotoxins are proteins which act at the presynaptic and postsynaptic membrane. Correctly predicting presynaptic and postsynaptic neurotoxins will provide important clues for drug-target discovery and drug design. In this study, we developed a theoretical method to discriminate presynapti...

journal_title：BioMed research international

authors： Tang H,Yang Y,Zhang C,Chen R,Huang P,Duan C,Zou P

更新日期：2017-01-01 00:00:00

abstract：:Background. For development of individualized treatment on a routine basis, transfer of patients' tumor tissue in a xenograft model (i.e., generation of patient-derived xenografts (PDX)) is desirable for molecular, biochemical, or functional analyses. Drawbacks are dissatisfactory tumor take rates, the necessity of fa...

journal_title：BioMed research international

authors： Gock M,Kühn F,Mullins CS,Krohn M,Prall F,Klar E,Linnebacher M

更新日期：2016-01-01 00:00:00

abstract：:Purpose. The aim of the present study was to elucidate the metabolic mechanisms associated with chronic fatigue syndrome (CFS) via an analysis of urine metabolites prior to and following exercise in a rat model. Methods. A rat model of CFS was established using restraint-stress, forced exercise, and crowded and noisy ...

journal_title：BioMed research international

authors： Shao C,Ren Y,Wang Z,Kang C,Jiang H,Chi A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00

abstract：:The establishment of the subgingival microbiota is dependent on successive colonization of the implant surface by bacterial species. Different implant surface topographies could influence the bacterial adsorption and therefore jeopardize the implant survival. This study evaluated the biofilm formation capacity of five...

journal_title：BioMed research international

authors： Pita PP,Rodrigues JA,Ota-Tsuzuki C,Miato TF,Zenobio EG,Giro G,Figueiredo LC,Gonçalves C,Gehrke SA,Cassoni A,Shibli JA

更新日期：2015-01-01 00:00:00

abstract：:Macrophages, especially their activation state, are closely related to the progression of diabetic nephropathy. Classically activated macrophages (M1) are proinflammatory effectors, while alternatively activated macrophages (M2) exhibit anti-inflammatory properties. 1,25-Dihydroxyvitamin D3 has renoprotective roles th...

journal_title：BioMed research international

authors： Zhang X,Zhou M,Guo Y,Song Z,Liu B

更新日期：2015-01-01 00:00:00

abstract：:Morphine is considered a highly potent analgesic agent used to relieve suffering of patients with cancer. Several in vitro and in vivo studies showed that morphine also modulates angiogenesis and regulates tumour cell growth. Unfortunately, the results obtained by these studies are still contradictory. In order to bet...

journal_title：BioMed research international

authors： Bimonte S,Barbieri A,Rea D,Palma G,Luciano A,Cuomo A,Arra C,Izzo F

更新日期：2015-01-01 00:00:00

abstract：:There has been no previous study using three-dimensional (3D) measurement on femoral tunnel characteristics according to the combined influence of various flexion angles of knee and transverse drill angles in single-bundle ACL reconstruction with transportal technique. The purpose of this study was to determine optima...

journal_title：BioMed research international

authors： Kim SH,Kim SJ,Choi CH,Kim D,Jung M

更新日期：2018-07-17 00:00:00

abstract：Background:Acute myocardial infarction (AMI) is regarded as an urgent clinical entity, and identification of differentially expressed genes, lncRNAs, and altered pathways shall provide new insight into the molecular mechanisms behind AMI. Materials and Methods:Microarray data was collected to identify key genes and ln...

journal_title：BioMed research international

authors： Sheng X,Fan T,Jin X

更新日期：2020-10-06 00:00:00

abstract：Purpose:Accumulated evidence suggests that reproductive factors are related to different breast cancer subtypes, but most studies on these relationships are mainly focused on middle-aged and older patients, and it remains unclear how reproductive factors impact different subtypes of breast cancer in young women. Metho...

journal_title：BioMed research international

authors： Wang JM,Wang J,Zhao HG,Liu TT,Wang FY

更新日期：2020-04-06 00:00:00

abstract：Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

journal_title：BioMed research international

authors： Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

更新日期：2020-08-14 00:00:00

abstract：PURPOSE:To evaluate the effect of applied suction during microkeratome-assisted laser in situ keratomileusis (LASIK) procedure on peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell-inner plexiform layer (GC-IPL) thickness. METHODS:89 patients (124 eyes) with established myopia ra...

journal_title：BioMed research international

authors： Zivkovic M,Jaksic V,Giarmoukakis A,Grentzelos M,Zlatanovic M,Zlatanovic G,Miljkovic A,Jovanovic S,Stamenkovic M,Kymionis G

更新日期：2017-01-01 00:00:00

abstract：:Several studies suggested that migraine attack onset shows a circadian variation; however, there has not been an overview and synthesis of these findings. A PubMed search with keywords "migraine" AND "circadian" resulted in ten studies directly investigating this topic. Results of these studies mostly show that migrai...

journal_title：BioMed research international

authors： Baksa D,Gecse K,Kumar S,Toth Z,Gal Z,Gonda X,Juhasz G

更新日期：2019-08-25 00:00:00

abstract：PURPOSE OF THE REPORT:There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role of (99m)Tc-ECD SPECT in a large number of subjects with craniosynostosis. MATERIALS AND METHODS:We prospectively analyzed a coh...

journal_title：BioMed research international

authors： Barik M,Bajpai M,Das RR,Malhotra A,Panda SS,Sahoo MK,Dwivedi S

更新日期：2014-01-01 00:00:00

abstract：:In continuance of our search for anticancer agents, we report herein the synthesis and anticancer activity of some novel oxadiazole analogues. The compounds were screened for anticancer activity as per National Cancer Institute (NCI US) protocol on leukemia, melanoma, lung, colon, CNS, ovarian, renal, prostate, and br...

journal_title：BioMed research international

authors： Ahsan MJ,Sharma J,Singh M,Jadav SS,Yasmin S

更新日期：2014-01-01 00:00:00

abstract：:Craniofacial development consists of a highly complex sequence of the orchestrated growth and fusion of facial processes. It is also known that craniofacial abnormalities can be detected in 1/3 of all patients with congenital diseases. Within the various craniofacial abnormalities, orofacial clefting is one of the mos...

journal_title：BioMed research international

authors： Kurosaka H

更新日期：2015-01-01 00:00:00

abstract：:Transient receptor potential polycystic 2 (TRPP2) exerts vital roles in various types of cancer; however, its underlying mechanisms remain largely unknown. This study is aimed at investigating whether knockdown of TRPP2 affected the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) signaling pathway and...

journal_title：BioMed research international

authors： Li K,Chen L,Lin Z,Zhu J,Fang Y,Du J,Shen B,Wu K,Liu Y

更新日期：2020-11-14 00:00:00

abstract：:In recent years, new prognostic indexes (PIs) for chronic lymphocytic leukemia (CLL), which include clinical, biological, and genetic variables, have been validated, highlighting the MD Anderson Cancer Center prognostic index (MDACC PI), the CLL-international prognostic index (CLL-IPI), and the Barcelona-Brno biomarke...

journal_title：BioMed research international

authors： Muñoz-Novas C,Poza-Santaella M,González-Gascón Y Marín I,Hernández-Sánchez M,Rodríguez-Vicente AE,Infante MS,Heras C,Foncillas MÁ,Marín K,Hernández-Rivas JM,Hernández JÁ

更新日期：2018-03-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths in Taiwan. CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis. We investigated the CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors related to H...

journal_title：BioMed research international

authors： Chou YE,Hsieh MJ,Chiou HL,Lee HL,Yang SF,Chen TY

更新日期：2014-01-01 00:00:00

abstract：:Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite effect under other...

journal_title：BioMed research international

authors： Advani A,Connelly KA,Advani SL,Thai K,Zhang Y,Kelly DJ,Gilbert RE

更新日期：2013-01-01 00:00:00

abstract：:The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5'-hydroxy auraptene (5'-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stimulator for osteobla...

journal_title：BioMed research international

authors： Abdallah BM,Ali EM,Elsawy H,Badr GM,Abdel-Moneim AM,Alzahrani AM

更新日期：2019-12-28 00:00:00

abstract：:Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarra...

journal_title：BioMed research international

authors： Zhou Y,Zhao Y,Du H,Suo Y,Chen H,Li H,Liang X,Li Q,Huang X

更新日期：2020-01-02 00:00:00

abstract：Objective:This study aims to investigate the effect of systemically administrated zoledronate on bone-implant fixation in animal models. Methods:We searched MEDLINE, Embase, and EBSCO for studies that explore the role of systemic or local zoledronate delivery in implant osseointegration in animal models. The Review Ma...

journal_title：BioMed research international

authors： He Y,Bao W,Wu XD,Huang W,Chen H,Li Z

更新日期：2019-09-22 00:00:00

abstract：Purpose:The aim of this study is to evaluate the effectiveness of laboratory serum tests in the diagnosis of infected nonunion. Methods:Forty-two patients suspected of having infected nonunion were investigated in the study. The serum levels of white blood-cell count (WBC), C-reactive protein (CRP), erythrocyte sedime...

journal_title：BioMed research international

authors： Wang S,Yin P,Quan C,Khan K,Wang G,Wang L,Cui L,Zhang L,Zhang L,Tang P

更新日期：2017-01-01 00:00:00

abstract：:Aim. This study aimed to evaluate the reliability of 3D-TMT, previously used only for dynamic testing, in a static cephalometric evaluation. Material and Method. A group of 40 patients (20 males and 20 females; mean age 14.2 ± 1.2 years; 12-18 years old) was included in the study. The measurements obtained by the 3D-T...

journal_title：BioMed research international

authors： Mummolo S,Nota A,Marchetti E,Padricelli G,Marzo G

更新日期：2016-01-01 00:00:00