Preoperative Chemotherapy for Gastric Cancer: Personal Interventions and Precision Medicine.

abstract：:The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin. Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the fie...

journal_title：BioMed research international

authors： Isaac VL,Chiari-Andréo BG,Marto JM,Moraes JD,Leone BA,Corrêa MA,Ribeiro HM

更新日期：2015-01-01 00:00:00

abstract：:This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages (pH 4.6, 150 mM lactic acid, aw = 0.92, temperature = 20 or 27°C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inacti...

journal_title：BioMed research international

authors： Lindqvist R,Barmark G

更新日期：2014-01-01 00:00:00

abstract：:Vascular aging, a specific type of organic aging, is related to age-dependent changes in the vasculature, including atherosclerotic plaques, arterial stiffness, fibrosis, and increased intimal thickening. Vascular aging could influence the threshold, process, and severity of various cardiovascular diseases, thus makin...

journal_title：BioMed research international

authors： Lin X,Zhan JK,Wang YJ,Tan P,Chen YY,Deng HQ,Liu YS

更新日期：2016-01-01 00:00:00

abstract：:This study applies the environmental Kuznets curve to test the relationship between the regional economic growth and the different types of agricultural nonpoint source pollution loads in the Ningxia Yellow River irrigation area by using the Johnes export coefficient method. Results show that the pollution load genera...

journal_title：BioMed research international

authors： Mao C,Zhai N,Yang J,Feng Y,Cao Y,Han X,Ren G,Yang G,Meng QX

更新日期：2013-01-01 00:00:00

abstract：:We have reported that folic acid, vitamin B12, and omega-3 fatty acids are interlinked in the one carbon cycle and have implications for fetal programming. Our earlier studies demonstrate that an imbalance in maternal micronutrients influence long chain polyunsaturated fatty acid metabolism and global methylation in r...

journal_title：BioMed research international

authors： Khot V,Kale A,Joshi A,Chavan-Gautam P,Joshi S

更新日期：2014-01-01 00:00:00

abstract：:Anopheles gambiae is the major malaria vector in Africa. Examining the molecular basis of A. gambiae traits requires knowledge of both genetic variation and genome-wide linkage disequilibrium (LD) map of wild A. gambiae populations from malaria-endemic areas. We sequenced the genomes of nine wild A. gambiae mosquitoes...

journal_title：BioMed research international

authors： Wang X,Afrane YA,Yan G,Li J

更新日期：2015-01-01 00:00:00

abstract：Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

journal_title：BioMed research international

authors： Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

更新日期：2020-08-14 00:00:00

abstract：:Influences of environmental variables and emulsifiers on lipase production of a Candida viswanathii strain were investigated. The highest lipase activity (101.1 U) was observed at 210 rpm, pH 6.0, and 27.5°C. Other fermentation parameters analyzed showed considerable rates of biomass yield (Y L/S = 1.381 g/g), lipase ...

journal_title：BioMed research international

authors： de Almeida AF,Tauk-Tornisielo SM,Carmona EC

更新日期：2013-01-01 00:00:00

abstract：:Ouabain, a cardiac glycoside found in plants, is primarily used in the treatment of congestive heart failure and arrhythmia because of its ability to inhibit Na(+)/K(+)-ATPase pump. Recently ouabain has been shown to exert anticancer effects but the underlying mechanism is not clear. Here, we explored the molecular me...

journal_title：BioMed research international

authors： Shin HK,Ryu BJ,Choi SW,Kim SH,Lee K

更新日期：2015-01-01 00:00:00

abstract：:Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

journal_title：BioMed research international

authors： Cui Y,Cai M,Stanley HE

更新日期：2017-01-01 00:00:00

abstract：Objectives:The purpose of the study was to evaluate the correlation between dynamic test results obtained on a stabilometric platform and the results achieved on the Y-balance test (Y-BT). Method:The study group consisted of 52 adolescent athletes, aged 14 to 17 years. Each participant was evaluated in the scope of th...

journal_title：BioMed research international

authors： Sikora D,Pałac M,Myśliwiec A,Wolny T,Linek P

更新日期：2020-11-12 00:00:00

abstract：:Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...

journal_title：BioMed research international

authors： Jiang C,Shao Q,Jin B,Gong R,Zhang M,Xu B

更新日期：2015-01-01 00:00:00

abstract：:Inflammation significantly contributes to the progression of chronic kidney disease (CKD). This study aimed to characterize Danggui Buxue Tang (DBT) renoprotection and relationship with NOD-like receptors family pyrin domain-containing 3 (NLRP3) inflammasome expression in rats with unilateral ureteral obstruction (UUO...

journal_title：BioMed research international

authors： Wang L,Ma J,Guo C,Chen C,Yin Z,Zhang X,Chen X

更新日期：2016-01-01 00:00:00

abstract：:Hemoglobin, which widely exists in all vertebrates and in some invertebrates, is possibly a precursor of antimicrobial peptides (AMPs). However, AMPs in the hemoglobin of invertebrates have been rarely investigated. This study is the first to report the full-length cDNA, prokaryotic expression, and antimicrobial activ...

journal_title：BioMed research international

authors： Niu R,Chen X

更新日期：2016-01-01 00:00:00

abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

journal_title：BioMed research international

authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

更新日期：2014-01-01 00:00:00

abstract：:Neurotrophic keratitis (NK) is a rare degenerative disease of the cornea caused by an impairment of corneal sensory innervation, characterized by decreased or absent corneal sensitivity resulting in epithelial keratopathy, ulceration, and perforation. The aetiopathogenesis of corneal sensory innervation impairment in ...

journal_title：BioMed research international

authors： Mantelli F,Nardella C,Tiberi E,Sacchetti M,Bruscolini A,Lambiase A

更新日期：2015-01-01 00:00:00

abstract：:Almost forty years ago, it was first hypothesized that an increased dietary intake of omega-3 polyunsaturated fatty acids (PUFA) from fish fat could exert protective effects against several pathologies. Decades of intense preclinical investigation have supported this hypothesis in a variety of model systems. Several c...

journal_title：BioMed research international

authors： Weylandt KH,Serini S,Chen YQ,Su HM,Lim K,Cittadini A,Calviello G

更新日期：2015-01-01 00:00:00

abstract：:Feed efficiency (FE) is an important trait affecting costs in swine industry. Investigation on FE-related genes in different tissues is valuable for molecular breeding. Hypothalamus is a convergent and integrated centre for multiple nutrient-related signals. The present study identified 363 differentially expressed (D...

journal_title：BioMed research international

authors： Hou Y,Hu M,Zhou H,Li C,Li X,Liu X,Zhao Y,Zhao S

更新日期：2018-12-26 00:00:00

abstract：:It is unclear whether the methyltransferase-like 14 (METTL14) protein promotes or suppresses cancer growth. We examined the association between METTL14 expression, cancer progression, and patient prognosis in a total of 398 breast cancer tissue specimens. Significantly fewer cancer tissue specimens compared with norma...

journal_title：BioMed research international

authors： Dong XF,Wang Y,Huang BF,Hu GN,Shao JK,Wang Q,Tang CH,Wang CQ

更新日期：2020-10-20 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：:The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals. Si...

journal_title：BioMed research international

authors： Doke M,Avecilla V,Felty Q

更新日期：2018-01-08 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

journal_title：BioMed research international

authors： Martínez MJ,Razuc M,Ponzoni I

更新日期：2019-02-17 00:00:00

abstract：:Contamination of heavy metals would threaten the water and soil resources; phytoremediation can be potentially used to remediate metal contaminated sites. We constructed the Phragmites australis artificial floating wetlands outside the Qingcaosha Reservoir in the Yangtze Estuary. Water characteristic variables were me...

journal_title：BioMed research international

authors： Huang X,Zhao F,Yu G,Song C,Geng Z,Zhuang P

更新日期：2017-01-01 00:00:00

abstract：:Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process. This process is under the control of local (e.g., growth factors ...

journal_title：BioMed research international

authors： Florencio-Silva R,Sasso GR,Sasso-Cerri E,Simões MJ,Cerri PS

更新日期：2015-01-01 00:00:00

abstract：:Hydrocephalus is a common neurological condition that can have traumatic ramifications and can be lethal without treatment. Nowadays, during therapy radiologists have to spend a vast amount of time assessing the volume of cerebrospinal fluid (CSF) by manual segmentation on Computed Tomography (CT) images. Further, som...

journal_title：BioMed research international

authors： Klimont M,Flieger M,Rzeszutek J,Stachera J,Zakrzewska A,Jończyk-Potoczna K

更新日期：2019-07-07 00:00:00

abstract：:Rapid bone defect filling with normal bone is a challenge in orthopaedics and dentistry. Strontium ranelate (SrRan) has been shown to in vitro decrease bone resorption and increase bone formation, and represents a potential agent with the capacity to accelerate bone defect filling. In this study, bone tibial defects o...

journal_title：BioMed research international

authors： Zacchetti G,Dayer R,Rizzoli R,Ammann P

更新日期：2014-01-01 00:00:00

abstract：:Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly(l-lactide-co-ε-caprolactone) (PLCL) scaffolds were printed by a 3D printing technology, low-temperature deposition manufacturing (LDM), and then PLCL scaffolds wer...

journal_title：BioMed research international

authors： He Y,Liu W,Guan L,Chen J,Duan L,Jia Z,Huang J,Li W,Liu J,Xiong J,Liu L,Wang D

更新日期：2018-02-28 00:00:00

abstract：:There is a controversial relationship between HLA-A2 and Alzheimer's disease (AD). It has been suggested a modifier effect on the risk that depends on genetic loadings. Thus, the aims of this study were to evaluate this relationship and to reveal genes associated with both concepts the HLA-A gene and AD. Consequently,...

journal_title：BioMed research international

authors： Cifuentes RA,Murillo-Rojas J

更新日期：2014-01-01 00:00:00

abstract：Purpose:To evaluate the influence of systemic and ocular factors on the foveal avascular zone (FAZ) area in young Chinese subjects' healthy eyes. Methods:The current observational, cross-sectional study included 344 eyes from 172 healthy individuals (103 women, 69 men). Optical coherence tomography angiography realize...

journal_title：BioMed research international

authors： Zhou Y,Zhou M,Gao M,Liu H,Sun X

更新日期：2020-03-24 00:00:00