Secretome Identifies Tenascin-X as a Potent Marker of Ovarian Cancer.

abstract：Objective:Cognitive impairment is considered to be an important complication of spinal cord injury (SCI), but its underlying mechanism remains unclear. The purpose of this study is to explore whether serum CCL21 can be used as a potential biomarker of cognitive impairment in SCI. Methods:In Neck-Shoulder and Lumbocrur...

journal_title：BioMed research international

authors： Chen Y,Liang L,Cao S,Hou G,Zhang Q,Ma H,Shi B

更新日期：2020-12-09 00:00:00

abstract：:Both human adipose tissue-derived mesenchymal stem cells (ASCs) and umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been explored as attractive mesenchymal stem cells (MSCs) sources, but very few parallel comparative studies of these two cell types have been made. We designed a side-by-side comparative st...

journal_title：BioMed research international

authors： Hu L,Hu J,Zhao J,Liu J,Ouyang W,Yang C,Gong N,Du L,Khanal A,Chen L

更新日期：2013-01-01 00:00:00

abstract：:Chagas disease is caused by Trypanosoma cruzi infection. Besides the host-related factors, such as immune response and genetic background, the parasite, strain, and occurrences of reinfection episodes, may influence disease outcome. Our results demonstrate that both the primary infection and the reinfection with the C...

journal_title：BioMed research international

authors： Reis Machado J,Silva MV,Borges DC,da Silva CA,Ramirez LE,dos Reis MA,Castellano LR,Rodrigues V,Rodrigues DB

更新日期：2014-01-01 00:00:00

abstract：:This study evaluated the presence of Acanthamoeba species in the Puzih River watershed, which features typical subtropical monsoon climate and is located just above the Tropic of Cancer in Taiwan. The relationship between the seasonal and geographical distributions of Acanthamoeba species in this rivershed was also in...

journal_title：BioMed research international

authors： Kao PM,Chou MY,Tao CW,Huang WC,Hsu BM,Shen SM,Fan CW,Chiu YC

更新日期：2013-01-01 00:00:00

abstract：:Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...

journal_title：BioMed research international

authors： Yau SY,Gil-Mohapel J,Christie BR,So KF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The genome-wide association studies (GWAS) have been successful during the last few years. A key challenge is that the interpretation of the results is not straightforward, especially for transacting SNPs. Integration of transcriptome data into GWAS may provide clues elucidating the mechanisms by which a gen...

journal_title：BioMed research international

authors： Jiang G,Chakraborty A,Wang Z,Boustani M,Liu Y,Skaar T,Li L

更新日期：2013-01-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) has a significant clinical relevance of being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available targeted agents. Increased aggressiveness of this tumor, as well as resistance to standard drug therapies, may be as...

journal_title：BioMed research international

authors： Collina F,Di Bonito M,Li Bergolis V,De Laurentiis M,Vitagliano C,Cerrone M,Nuzzo F,Cantile M,Botti G

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to describe the clinical and demographic characteristics of UC in Bahia, a Brazilian state, and to identify the variables associated with extensive colitis, steroid therapy, immunosuppression, and colectomy. METHODS:In this cross-sectional study UC patients were interviewed, ...

journal_title：BioMed research international

authors： da Silva BC,Lyra AC,Mendes CM,Ribeiro CP,Lisboa SR,de Souza MT,Portela RC,Santana GO

更新日期：2015-01-01 00:00:00

abstract：Background:This study investigated the potential therapeutic effects of acupoint catgut embedding (ACE) at ST36 and BL13 on lipopolysaccharide- (LPS-) induced acute respiratory distress syndrome (ARDS) in rats. Materials and Methods:Male Sprague-Dawley rats were randomized into the normal saline (NS group with a sham ...

journal_title：BioMed research international

authors： Li D,Sun T,Chi L,Zhao D,Li W

更新日期：2020-05-02 00:00:00

abstract：Background:In resource limited settings, HIV/AIDS patients lack access to sufficient nutritious foods, which poses challenges to the success of antiretroviral therapy. HIV/AIDS and malnutrition are still major public health problems in Ethiopia. Though measuring nutritional status is an essential part of ART program, l...

journal_title：BioMed research international

authors： Gebremichael DY,Hadush KT,Kebede EM,Zegeye RT

更新日期：2018-05-06 00:00:00

abstract：Background and Aims:The value of hepatocyte regeneration in predicting the outcomes of hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) is not fully assessed. The present study was aimed at establishing a novel scoring system to predict patients' outcomes within 3 months by applying serological indicators ...

journal_title：BioMed research international

authors： Wang X,Sun M,Yang X,Gao L,Weng M,Yang D,Li H,Zhou X,Li J,Qin S,Zhou D,Wu X,Tang S,Zeng W

更新日期：2020-08-06 00:00:00

abstract：:The use of endotamponade agents has gained a major role in the management of macular complications of high myopia. Myopic foveoschisis and macular hole are the main macular complication of pathologic myopia, this growing condition that is a main cause of visual loss, especially in patients at a younger age. We discuss...

journal_title：BioMed research international

authors： Valldeperas X,Lorenzo-Carrero J

更新日期：2014-01-01 00:00:00

abstract：:Healthcare professionals undergo high levels of occupational stress as a result of their working conditions. Thus, the aim of this study is to develop a model that focuses on healthcare professionals so as to analyze the influence that job demands, control, social support, and recognition have on the likelihood that a...

journal_title：BioMed research international

authors： García-Herrero S,Lopez-Garcia JR,Herrera S,Fontaneda I,Báscones SM,Mariscal MA

更新日期：2017-01-01 00:00:00

abstract：:A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...

journal_title：BioMed research international

authors： Luo D,Shan Z,Liu Q,Cai S,Li Q,Li X

更新日期：2020-11-17 00:00:00

abstract：:Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including Acanthamoeba spp. The aim of this study was to determine the expression of TLR2 and TLR4 in the eyes of mice following intranasal infection with Acanthamoeba spp. in relation to the host's immunological status. Am...

journal_title：BioMed research international

authors： Kot K,Kosik-Bogacka D,Łanocha-Arendarczyk N,Wojtkowiak-Giera A,Kolasa-Wołosiuk A

更新日期：2019-06-12 00:00:00

abstract：BACKGROUND:The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). METHODS:Functional reannotation for the human lncRNA was carried out by ncFANs. Real-time quantitative PCR was used to v...

journal_title：BioMed research international

authors： Gao W,Chan JY,Wong TS

更新日期：2014-01-01 00:00:00

abstract：:SARS-CoV-2 pandemic and COVID-19 diffusion have recently become an international public health emergency. Cancer patients, as a frail population, are particularly exposed to the risk related to infections. The clinical decision-making process and the organizational workflow of radiotherapy department should be revised...

journal_title：BioMed research international

authors： Franco P,Kochbati L,Siano M,De Bari B

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of docetaxel plus oxaliplatin and capecitabine (DOX) in the first line treatment of advanced gastric adenocarcinoma. METHODS:A total of 37 patients were enrolled into this study, and they received DOX regimen (docetaxel 75 mg/m² and oxaliplatin 130 mg/m² intravenous infusi...

journal_title：BioMed research international

authors： Liu Y,Ye Z,Xi W,Ma T,Shi M,Yang L,Zhu Z,Zhang J

更新日期：2013-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...

journal_title：BioMed research international

authors： Jiang C,Shao Q,Jin B,Gong R,Zhang M,Xu B

更新日期：2015-01-01 00:00:00

abstract：:Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal art...

journal_title：BioMed research international

authors： Buys-Gonçalves GF,Abreu LAS,Gregorio BM,Sampaio FJB,Pereira-Sampaio MA,de Souza DB

更新日期：2019-02-07 00:00:00

abstract：:Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...

journal_title：BioMed research international

authors： Fernandes-Lima F,Gregório BM,Nascimento FAM,Costa WS,Gallo CBM,Sampaio FJB

更新日期：2018-04-23 00:00:00

abstract：:Aims. We describe a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify and compare simultaneously global methylation and hydroxymethylation in human DNA of different tissues. Materials and Methods. Blood and saliva DNA from fourteen volunteers was processed for epigenetic endpoints using LC-M...

journal_title：BioMed research international

authors： Godderis L,Schouteden C,Tabish A,Poels K,Hoet P,Baccarelli AA,Van Landuyt K

更新日期：2015-01-01 00:00:00

abstract：:The success rate of oral implants is lower in type 2 diabetes mellitus (T2DM) patients than in nondiabetic subjects; functional impairment of bone marrow-derived mesenchymal stem cells (BMSCs) is an important underlying cause. Many factors in the blood can act on BMSCs to regulate their biological functions and influe...

journal_title：BioMed research international

authors： Liang C,Sun R,Xu Y,Geng W,Li J

更新日期：2020-06-07 00:00:00

abstract：:Postoperative surgical site infections (SSIs) are more common complications after spinal surgery. SSIs often require extended hospitalisation and may worsen overall clinical outcomes. A retrospective database review of consecutive patients with traditional open lumbar spinal surgery was performed. SSIs patients were i...

journal_title：BioMed research international

authors： Liu JT,Liao WJ,Chang CS,Chen YH

更新日期：2015-01-01 00:00:00

abstract：:We performed a retrospective review of 40 consecutive modern cementless THAs with 65-month mean followup in 34 patients under the age of 30 primarily for diagnoses other than inflammatory arthritis. We found acceptable functional improvement and radiographic outcomes at mean 5-year followup. We found a high transfusio...

journal_title：BioMed research international

authors： Gililland JM,Anderson LA,Erickson J,Pelt CE,Peters CL

更新日期：2013-01-01 00:00:00

abstract：:Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred mo...

journal_title：BioMed research international

authors： Shahidi M,Phillips RA,Chik CL

更新日期：2019-03-13 00:00:00

abstract：:Chronic obesity is a known risk factor for metabolic syndrome. However, little is known about pathological changes in the small intestine associated with chronic obesity. This study investigated cellular and subcellular level changes in the small intestine of obese mice. In this study, a mouse model of obesity was est...

journal_title：BioMed research international

authors： Nakadate K,Motojima K,Hirakawa T,Tanaka-Nakadate S

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine interfractional changes of lung tumor centroid position and tumor regression during stereotactic body radiation therapy (SBRT). METHODS AND MATERIALS:34 patients were treated by SBRT in 4-5 fractions to a median dose of 50 Gy. The CT scans acquired for verification were registered with simulation ...

journal_title：BioMed research international

authors： Sun Y,Lu Y,Cheng S,Guo W,Ye K,Zhao H,Zheng X,Li D,Wang S,Yang C,Ge H

更新日期：2014-01-01 00:00:00

abstract：Objective:To explore the ability of asiatic acid to interfere with the invasion and proliferation of breast cancer cells by inhibiting WAVE3 expression and activation through the PI3K/AKT signaling pathway. Methods:The MDA-MB-231 cells with strong invasiveness were screened by transwell assay, and plasmids with high e...

journal_title：BioMed research international

authors： Gou XJ,Bai HH,Liu LW,Chen HY,Shi Q,Chang LS,Ding MM,Shi Q,Zhou MX,Chen WL,Zhang LM

更新日期：2020-02-10 00:00:00

abstract：:The aim of this study was to assess the diagnostic accuracy of subjective ultrasound evaluation of myometrial invasion of endometrial cancer and to compare its accuracy to objective methods. All consecutive patients with histologically proven endometrial cancer, who underwent ultrasound evaluation followed by surgical...

journal_title：BioMed research international

authors： Frühauf F,Zikan M,Semeradova I,Dundr P,Nemejcova K,Dusek L,Cibula D,Fischerova D

更新日期：2017-01-01 00:00:00