Effect of the Abnormal Expression of BMP-4 in the Blood of Diabetic Patients on the Osteogenic Differentiation Potential of Alveolar BMSCs and the Rescue Effect of Metformin: A Bioinformatics-Based Study.

abstract：OBJECTIVE:We examined the diagnostic value of subjective memory complaints (SMCs) assessed with a single item in a large cross-sectional cohort consisting of families with autosomal dominant Alzheimer's disease (ADAD) participating in the Dominantly Inherited Alzheimer Network (DIAN). METHODS:The baseline sample of 18...

journal_title：BioMed research international

authors： Laske C,Sohrabi HR,Jasielec MS,Müller S,Koehler NK,Gräber S,Förster S,Drzezga A,Mueller-Sarnowski F,Danek A,Jucker M,Bateman RJ,Buckles V,Saykin AJ,Martins RN,Morris JC,Dominantly Inherited Alzheimer Network Dian

更新日期：2015-01-01 00:00:00

abstract：:Diabetes has become the third most serious threat to human health, after cancer and cardiovascular disease. Notably, Lactobacillus brevis is the most common species of LAB that produces γ-aminobutyric acid (GABA). The aim of this study is to clarify the effect of time, strain types, antibiotic concentrations, differen...

journal_title：BioMed research international

authors： Abdelazez A,Abdelmotaal H,Evivie SE,Melak S,Jia FF,Khoso MH,Zhu ZT,Zhang LJ,Sami R,Meng XC

更新日期：2018-09-19 00:00:00

abstract：:Host jump can result in deadly pandemic events when avian influenza A viruses broaden their host specificity and become able to infect mammals, including humans. Haemagglutinin-the major capsid protein in influenza A viruses-is subjected to high rate mutations, of which several occur at its "head": the receptor-bindin...

journal_title：BioMed research international

authors： Righetto I,Filippini F

更新日期：2018-05-17 00:00:00

abstract：:Schistosomiasis, caused by infection with Schistosoma species, remains an important parasitic zoonosis. Thioredoxin glutathione reductase of Schistosoma japonicum (SjTGR) plays an important role in the development of the parasite and for its survival. Here we present a recombinant plasmid DNA vaccine, pVAX1/SjTGR, to ...

journal_title：BioMed research international

authors： Cao Y,Zhao B,Han Y,Zhang J,Li X,Qiu C,Wu X,Hong Y,Ai D,Lin J,Fu Z

更新日期：2013-01-01 00:00:00

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：:Quantitative magnetic resonance imaging (qMRI) is a promising approach to detect early cartilage degeneration. However, there is no consensus on which cartilage component contributes to the tissue's qMRI signal properties. T1, T1ρ, and T2⁎ maps of cartilage samples (n = 8) were generated on a clinical 3.0-T MRI system...

journal_title：BioMed research international

authors： Thüring J,Linka K,Itskov M,Knobe M,Hitpaß L,Kuhl C,Truhn D,Nebelung S

更新日期：2018-05-15 00:00:00

abstract：Background:Adenosine, derived from the degradation of ATP via ectonucleotidases CD39 and CD73, is a critical immunosuppressive metabolite in the hypoxic microenvironment of tumor tissue. Adenosine signaling via A2aR can inhibit the antitumor immune response of CD8+ T cells. CD39 and CD73 high-expressing Tregs play a cr...

journal_title：BioMed research international

authors： Shi L,Feng M,Du S,Wei X,Song H,Yixin X,Song J,Wenxian G

更新日期：2019-12-14 00:00:00

abstract：:Angiogenesis and lymphangiogenesis are important in the proliferation and survival of the malignant hematopoietic neoplasms, including non-Hodgkin's lymphomas (NHLs). Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) play an important role in the initiation of angiogenesis. Both VEGF ...

journal_title：BioMed research international

authors： Wróbel T,Mazur G,Dzietczenia J,Gębura K,Kuliczkowski K,Bogunia-Kubik K

更新日期：2013-01-01 00:00:00

abstract：:Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The more rationale approach to delay the progression of sarcopenia is based on the combination of proper nutrition, possibly associated with the use of dietary supplements and a regular exercise program. ...

journal_title：BioMed research international

authors： Rondanelli M,Faliva M,Monteferrario F,Peroni G,Repaci E,Allieri F,Perna S

更新日期：2015-01-01 00:00:00

abstract：:Tissue regeneration has become a promising treatment for craniomaxillofacial bone defects such as alveolar clefts. This study sought to assess the efficacy of lateral ramus cortical plate with buccal fat pad derived mesenchymal stem cells (BFSCs) in treatment of human alveolar cleft defects. Ten patients with unilater...

journal_title：BioMed research international

authors： Khojasteh A,Kheiri L,Behnia H,Tehranchi A,Nazeman P,Nadjmi N,Soleimani M

更新日期：2017-01-01 00:00:00

abstract：Background:Ischemic heart disease (IHD) is the major cause of death in patients with cardiovascular disease. Cardiac remodeling is a common pathological change following myocardial infarction (MI), and cardiomyocyte apoptosis plays a key role in this change. Transcription factor recombination signal-binding protein-J (...

journal_title：BioMed research international

authors： He Y,Pang S,Huang J,Zhu K,Tong J,Tang Y,Ma G,Chen L

更新日期：2018-07-03 00:00:00

abstract：Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...

journal_title：BioMed research international

authors： Nie H,Hu Y,Guo W,Wang W,Yang Q,Dong Q,Tang Y,Li Q,Tang Z

更新日期：2020-06-07 00:00:00

abstract：:We aim to investigate the effects of curcumin on preventing diabetes-induced vascular inflammation in association with its actions on Txnip, ICAM-1, and NOX2 enzyme expressions. Male Wistar rats were divided into four groups: control (CON), diabetic (DM; streptozotocin (STZ), i.v. 55 mg/kg BW), control-treated with cu...

journal_title：BioMed research international

authors： Wongeakin N,Bhattarakosol P,Patumraj S

更新日期：2014-01-01 00:00:00

abstract：:This study described a TaqMan based real-time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = -3.249...

journal_title：BioMed research international

authors： Chen R,Chen Q,Wu X,Che Y,Wang C,Wang L,Yan S,Zhou L

更新日期：2020-01-10 00:00:00

abstract：Introduction:In literature, it is well documented that migration is associated with adverse perinatal outcomes in many countries over the world. But in Turkey, health care providers and obstetricians had to face the effects of migration for the first time after civil war in Syria. Hence, this situation motivated us to ...

journal_title：BioMed research international

authors： Col Madendag I,Eraslan Sahin M,Madendag Y,Sahin E,Demir MB,Ozdemir F,Acmaz G,Muderris II

更新日期：2019-11-05 00:00:00

abstract：INTRODUCTION:Tuberculosis is still one of the most important health problems in developing countries and increasing drug resistance is the main concern for its treatment. This study was designed to characterize the drug resistant Mycobacterium tuberculosis isolated from patients suffering from pulmonary tuberculosis in...

journal_title：BioMed research international

authors： Tavanaee Sani A,Shakiba A,Salehi M,Bahrami Taghanaki HR,Ayati Fard SF,Ghazvini K

更新日期：2015-01-01 00:00:00

abstract：:Cellulase from Aspergillus niger was immobilized onto β-cyclodextrin-conjugated magnetic particles by silanization and reductive amidation. The immobilized cellulase gained supermagnetism due to the magnetic nanoparticles. Ninety percent of cellulase was immobilized, but the activity of immobilized cellulase decreased...

journal_title：BioMed research international

authors： Huang PJ,Chang KL,Hsieh JF,Chen ST

更新日期：2015-01-01 00:00:00

abstract：:Molecular imaging based personalized therapy has been a fascinating concept for individualized therapeutic strategy, which is able to attain the highest efficacy and reduce adverse effects in certain patients. Theranostics, which integrates diagnostic testing to detect molecular targets for particular therapeutic moda...

journal_title：BioMed research international

authors： Ahn BC

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...

journal_title：BioMed research international

authors： Deylam Salehi M,Ferdosi-Shahandashti E,Yahyapour Y,Khafri S,Pournajaf A,Rajabnia R

更新日期：2017-01-01 00:00:00

abstract：:Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediter...

journal_title：BioMed research international

authors： Karygianni L,Cecere M,Skaltsounis AL,Argyropoulou A,Hellwig E,Aligiannis N,Wittmer A,Al-Ahmad A

更新日期：2014-01-01 00:00:00

abstract：:A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...

journal_title：BioMed research international

authors： Luo D,Shan Z,Liu Q,Cai S,Li Q,Li X

更新日期：2020-11-17 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：:Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic g...

journal_title：BioMed research international

authors： Li T,Zhu J,Deng F,Wu W,Zheng Z,Lv C,Li Y,Xiang W,Lu X,Qin S

更新日期：2019-03-07 00:00:00

abstract：:Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal muco...

journal_title：BioMed research international

authors： Xiong S,Wang J,Zhu W,Yang K,Ding G,Li X,Eun DD

更新日期：2020-07-27 00:00:00

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00

abstract：:Neem (Azadirachta indica A. Juss) oil (NO) was assayed against forty-eight isolates of Escherichia coli by standardised disc diffusion test and microdilution test. By molecular biology characterization, fourteen isolates resulted in diarrheagenic E. coli with sixteen primer pairs that specifically amplify unique seque...

journal_title：BioMed research international

authors： Del Serrone P,Toniolo C,Nicoletti M

更新日期：2015-01-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterized by variable expressivity, age penetrance, and a high heterogeneity. The transcriptional profile (miRNAs, mRNAs), epigenetic modifications, and posttranslational modifications seem to be highly relevant for the onset of the disease. miRNAs...

journal_title：BioMed research international

authors： Roma-Rodrigues C,Raposo LR,Fernandes AR

更新日期：2015-01-01 00:00:00

abstract：:The study aimed to determine the suitability of testing the saliva of kickboxing athletes to show changes in biochemical parameters in dynamic of training. 8 elite male athletes (mean age 17.29± 0.31 years, body mass 66.82± 3.46kg, with 5.62±0.96 years of training experience) participated in the study. Indicators of l...

journal_title：BioMed research international

authors： Volodchenko OA,Podrigalo LV,Iermakov SS,Żychowska MT,Jagiełło W

更新日期：2019-01-10 00:00:00

abstract：:Enzymes play important roles in most of the biological processes. Although only a small fraction of residues are directly involved in catalytic reactions, these catalytic residues are the most crucial parts in enzymes. The study of the fundamental and unique features of catalytic residues benefits the understanding of...

journal_title：BioMed research international

authors： Chien YT,Huang SW

更新日期：2013-01-01 00:00:00

abstract：:Combination antiemetic regimens targeting multiple molecular pathways associated with emesis have become the standard of care for prevention of chemotherapy-induced nausea and vomiting (CINV) related to highly and moderately emetogenic chemotherapies. Antiemetic consensus guidelines from several professional societies...

journal_title：BioMed research international

authors： Hesketh PJ,Aapro M,Jordan K,Schwartzberg L,Bosnjak S,Rugo H

更新日期：2015-01-01 00:00:00