Screening Potential Probiotic Characteristics of Lactobacillus brevis Strains In Vitro and Intervention Effect on Type I Diabetes In Vivo.

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：:Uveitic glaucoma (UG) typically is associated with very high intraocular pressure (IOP) and more intense optic nerve damage than other glaucoma types. This secondary glaucoma requires an early diagnosis and adequate management of both uveitis and glaucoma. It is mandatory to identify the mechanisms of IOP elevation th...

journal_title：BioMed research international

authors： Muñoz-Negrete FJ,Moreno-Montañés J,Hernández-Martínez P,Rebolleda G

更新日期：2015-01-01 00:00:00

abstract：:To evaluate the role of Cystatin C (Cys-C) in tumorigenesis and progression of prostate cancer (PCa), we retrospectively collected the clinical information from the records of 492 benign prostatic hyperplasia (BPH), 48 prostatic intraepithelial neoplasia (PIN), and 173 PCa patients, whose disease was newly diagnosed a...

journal_title：BioMed research international

authors： Yang F,Li D,Di Y,Zhang Y,Zang Y,Ren J,Yan L,Zhou Z,Liu H,Xu Z

更新日期：2017-01-01 00:00:00

abstract：:Aim. To explore the effects of curcumin on phosphate carrier (PiC) and its role in protection against doxorubicin induced myocyte toxicity. Methods. Using H9c2 cell line, the cardiotoxic effect of doxorubicin and its mitigation by curcumin were studied. H9c2 cells were cultured with doxorubicin and/or curcumin at vari...

journal_title：BioMed research international

authors： Junkun L,Erfu C,Tony H,Xin L,Sudeep KC,Mingliang Z,Yanqin W,XiangQian Q

更新日期：2016-01-01 00:00:00

abstract：Objective:To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods:We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combin...

journal_title：BioMed research international

authors： Xu Z,Wu Z,Zhang J,Zhou R,Wu J,Yu B

更新日期：2020-08-12 00:00:00

abstract：:Because of their high incidence and mortality solid cancers are a major health problem worldwide. Although several new biomarkers and potential targets for therapy have been identified through biomolecular research in the last years, the effects on patients' outcome are still unsatisfactory. Increasing evidence indica...

journal_title：BioMed research international

authors： Lastraioli E,Lottini T,Bencini L,Bernini M,Arcangeli A

更新日期：2015-01-01 00:00:00

abstract：:We aimed to predict the ten-year cardiovascular disease (CVD) risk among low-income urban dwellers of metropolitan Malaysia. Participants were selected from a cross-sectional survey conducted in Kuala Lumpur. To assess the 10-year CVD risk, we employed the Framingham risk scoring (FRS) models. Significant determinants...

journal_title：BioMed research international

authors： Su TT,Amiri M,Mohd Hairi F,Thangiah N,Bulgiba A,Majid HA

更新日期：2015-01-01 00:00:00

abstract：:Methylmercury, organic form of mercury, can increase the number of abnormal sperm and decrease sperm concentration and testosterone levels possibly due to the damage caused by reactive species to germ and Leydig cells. Maná-cubiu (Solanum sessiliflorum Dunal) is a native fruit from Amazon rich in iron, zinc, niacin, p...

journal_title：BioMed research international

authors： Frenedoso da Silva R,Missassi G,dos Santos Borges C,Silva de Paula E,Hornos Carneiro MF,Grotto D,Barbosa Junior F,De Grava Kempinas W

更新日期：2014-01-01 00:00:00

abstract：:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...

journal_title：BioMed research international

authors： Wang P,Wang J,Ma J,Jin G,Guan X

更新日期：2017-01-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. AS patients also display a high prevalence of features clustered under the name of metabolic syndrome (MeS). Anti-TNF- α therapy was found to be effecti...

journal_title：BioMed research international

authors： Genre F,López-Mejías R,Miranda-Filloy JA,Ubilla B,Carnero-López B,Blanco R,Pina T,González-Juanatey C,Llorca J,González-Gay MA

更新日期：2014-01-01 00:00:00

abstract：:This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

journal_title：BioMed research international

authors： Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was to perform a structural characterization and evaluate the in vitro safety profile and in vitro antioxidant activity of liquid crystalline systems (LCS) with and without retinyl palmitate (RP). LCS containing polyether functional siloxane (PFS) as a surfactant, silicon glycol copolymer (...

journal_title：BioMed research international

authors： Oliveira MB,do Prado AH,Bernegossi J,Sato CS,Lourenço Brunetti I,Scarpa MV,Leonardi GR,Friberg SE,Chorilli M

更新日期：2014-01-01 00:00:00

abstract：:Aim. This study aimed to evaluate the reliability of 3D-TMT, previously used only for dynamic testing, in a static cephalometric evaluation. Material and Method. A group of 40 patients (20 males and 20 females; mean age 14.2 ± 1.2 years; 12-18 years old) was included in the study. The measurements obtained by the 3D-T...

journal_title：BioMed research international

authors： Mummolo S,Nota A,Marchetti E,Padricelli G,Marzo G

更新日期：2016-01-01 00:00:00

abstract：Background:Focal hyperhidrosis mostly affects the axillae, hands, feet, and face. For the management, several techniques are used. The aim of this study was to investigate the effects of direct current administration on the hyperhidrosis disease severity scale (HDSS) in patients with axillary hyperhidrosis that have va...

journal_title：BioMed research international

authors： Şener S,Karakoç Y

更新日期：2019-10-31 00:00:00

abstract：:The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals. Si...

journal_title：BioMed research international

authors： Doke M,Avecilla V,Felty Q

更新日期：2018-01-08 00:00:00

abstract：:Previous study showed that East Asian mtDNA haplogroups, especially those of Koreans, could be successfully assigned by the coupled use of analyses on coding region SNP markers and control region mutation motifs. In this study, we tried to see if the same triple multiplex analysis for coding regions SNPs could be also...

journal_title：BioMed research international

authors： Oh CS,Lee SD,Kim YS,Shin DH

更新日期：2015-01-01 00:00:00

abstract：:Autophagy is involved in the development of numerous illnesses, including ischemia/reperfusion (I/R). Endothelial nitric oxide synthase (eNOS) participates in the protective effects of ischemic postconditioning (IPostC). However, it remains unclear whether eNOS-mediated autophagy serves as a critical role in IPostC in...

journal_title：BioMed research international

authors： Shao J,Miao C,Geng Z,Gu M,Wu Y,Li Q

更新日期：2019-02-10 00:00:00

abstract：:Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The h...

journal_title：BioMed research international

authors： Lu J,Li Y,Hu D,Chen X,Liu Y,Wang L,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：:Ceramic materials show excellent esthetic behavior, along with an absence of hypersensitivity, making them a possible alternative implant material in dental surgery. However, their surface properties enable only limited osseointegration compared to titanium implants. Within this study, a novel surface coating techniqu...

journal_title：BioMed research international

authors： Markhoff J,Mick E,Mitrovic A,Pasold J,Wegner K,Bader R

更新日期：2014-01-01 00:00:00

abstract：:The study quantified the relative absolute PSCA level in relation to the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) level in the peripheral blood of 478 hormone-naive prostate cancer (PC) patients who underwent radical prostatectomy from 2005 to 2012 and evaluated its prognostic significance as a risk factor for...

journal_title：BioMed research international

authors： Kim SH,Park WS,Lee SJ,Choi MK,Yeon SM,Joo JN,Ko A,Lee ES,Joung JY,Seo HK,Chung J,Lee KH

更新日期：2015-01-01 00:00:00

abstract：:Diabetes-triggered apoptosis of Schwann cells (SC) contributes to the degradation of diabetic peripheral neuropathy (DNP). In recent years, mesenchymal stem cells (MSC) were applied to DPN repair and it was demonstrated that paracrine secretion played a key role in neuroprotection exerted by MSC. Erythropoietin (EPO) ...

journal_title：BioMed research international

authors： Zhang S,Shi B

更新日期：2017-01-01 00:00:00

abstract：:The relationship between oxidative stress and miRNA changes in placenta as a potential mechanism involved in preeclampsia (PE) is not fully elucidated. We investigated the impact of oxidative stress on miRNAs and mRNA expression profiles of genes associated with PE in villous 3A first trimester trophoblast cells expos...

journal_title：BioMed research international

authors： Cross CE,Tolba MF,Rondelli CM,Xu M,Abdel-Rahman SZ

更新日期：2015-01-01 00:00:00

abstract：:Periodontal remodeling and alveolar bone resorption and formation play essential roles during orthodontic tooth movement (OTM). In the process, human periodontal ligament cells (HPDLCs) sense and respond to orthodontic forces, contributing to the alveolar bone formation. However, the underlying mechanism in this proce...

journal_title：BioMed research international

authors： Yang Y,Wang BK,Chang ML,Wan ZQ,Han GL

更新日期：2018-11-05 00:00:00

abstract：Background:Though there are several prognostic models, there is no protein-related prognostic model. The aim of this study is to identify possible prognostic-related proteins in bladder urothelial carcinoma and to try to predict the prognosis of bladder urothelial carcinoma based on these proteins. Methods:Profile dat...

journal_title：BioMed research international

authors： Luo Q,Zhang X

更新日期：2020-07-31 00:00:00

abstract：Purpose:The aim of this study is to evaluate the effectiveness of laboratory serum tests in the diagnosis of infected nonunion. Methods:Forty-two patients suspected of having infected nonunion were investigated in the study. The serum levels of white blood-cell count (WBC), C-reactive protein (CRP), erythrocyte sedime...

journal_title：BioMed research international

authors： Wang S,Yin P,Quan C,Khan K,Wang G,Wang L,Cui L,Zhang L,Zhang L,Tang P

更新日期：2017-01-01 00:00:00

abstract：:Giardia duodenalis is a small intestinal protozoan parasite of several terrestrial vertebrates. This work aims to assess the genotypic variability of Giardia duodenalis isolates from cattle, sheep and pigs in the Southeast of Brazil, by comparing the standard characterization between glutamate dehydrogenase (gdh) and ...

journal_title：BioMed research international

authors： Fava NM,Soares RM,Scalia LA,Kalapothakis E,Pena IF,Vieira CU,Faria ES,Cunha MJ,Couto TR,Cury MC

更新日期：2013-01-01 00:00:00

abstract：Background:Uveitis is a known ophthalmologic manifestation of seronegative spondyloarthropathy, including psoriatic arthritis. However, the data is less clear among patients with psoriasis due to the limited number of published studies. Aims:To investigate whether the risk of incident and prevalent uveitis is elevated...

journal_title：BioMed research international

authors： Chaiyabutr C,Ungprasert P,Silpa-Archa N,Wongpraparut C,Chularojanamontri L

更新日期：2020-07-15 00:00:00

abstract：:Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route ...

journal_title：BioMed research international

authors： Kundu SK,Sharma AR,Lee SS,Sharma G,Doss CG,Yagihara S,Kim DY,Nam JS,Chakraborty C

更新日期：2014-01-01 00:00:00

abstract：:Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly(l-lactide-co-ε-caprolactone) (PLCL) scaffolds were printed by a 3D printing technology, low-temperature deposition manufacturing (LDM), and then PLCL scaffolds wer...

journal_title：BioMed research international

authors： He Y,Liu W,Guan L,Chen J,Duan L,Jia Z,Huang J,Li W,Liu J,Xiong J,Liu L,Wang D

更新日期：2018-02-28 00:00:00

abstract：:Glioma of infiltrative nature is challenging for surgeons to achieve tumor-specific and maximal resection. Raman spectroscopy provides structural information on the targeted materials as vibrational shifts. We utilized Raman spectroscopy to distinguish invasive tumors from normal tissues. Spectra obtained from replica...

journal_title：BioMed research international

authors： Tanahashi K,Natsume A,Ohka F,Momota H,Kato A,Motomura K,Watabe N,Muraishi S,Nakahara H,Saito Y,Takeuchi I,Wakabayashi T

更新日期：2014-01-01 00:00:00