Abstract:
:Previous study showed that East Asian mtDNA haplogroups, especially those of Koreans, could be successfully assigned by the coupled use of analyses on coding region SNP markers and control region mutation motifs. In this study, we tried to see if the same triple multiplex analysis for coding regions SNPs could be also applicable to ancient samples from East Asia as the complementation for sequence analysis of mtDNA control region. By the study on Joseon skeleton samples, we know that mtDNA haplogroup determined by coding region SNP markers successfully falls within the same haplogroup that sequence analysis on control region can assign. Considering that ancient samples in previous studies make no small number of errors in control region mtDNA sequencing, coding region SNP analysis can be used as good complimentary to the conventional haplogroup determination, especially of archaeological human bone samples buried underground over long periods.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Oh CS,Lee SD,Kim YS,Shin DHdoi
10.1155/2015/850648subject
Has Abstractpub_date
2015-01-01 00:00:00pages
850648eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
历史文章,杂志文章abstract:PURPOSE:To identify an effective method to prevent myopia progression by characterizing the regulation of matrix metalloproteinase- (MMP-) 2 expression and its secretion from scleral fibroblasts and retinal pigment epithelium (RPE) cells by miR-29a. METHODS:The effects of miR-29a on the growth of scleral fibroblasts a...
journal_title:BioMed research international
pub_type: 杂志文章
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abstract::The repair of bone defects is a big challenge in reconstructive surgery. Periosteal distraction osteogenesis (PDO), as a promising technique used for bone regeneration, forms a space between the periosteum and bone cortex to regenerate the new bone merely by distracting the periosteum. In order to investigate the infl...
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doi:10.1155/2018/7021826
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pub_type: 杂志文章
doi:10.1155/2017/2168767
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3296437
更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1155/2019/3951574
更新日期:2019-01-23 00:00:00
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pub_type: 杂志文章
doi:10.1155/2017/8017541
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3264194
更新日期:2017-01-01 00:00:00
abstract:Purpose:Technetium-99m diethylene triamine pentaacetic acid (Tc-99m DTPA) renal dynamic scintigraphy is a widely used imaging technique that evaluates renal function of patients with extrarenal abnormalities, but its clinical value in potentially offering us information on proliferation of liposarcoma has not yet been ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9765162
更新日期:2020-02-22 00:00:00
abstract::Natural medical plant is considered as a good source of tyrosinase inhibitors. Red vine leaf extract (RVLE) can be applied to a wide variety of medical disciplines, such as treatments for chronic venous insufficiency over many decades. This study investigated the tyrosinase inhibitory activity of RVLE containing galli...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/5232680
更新日期:2017-01-01 00:00:00
abstract::MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes. Their deregulation is thus often causative of human malignancies, including cancers. Numerous studies have implicated microRNAs in the different steps of tumorigenesis including initiation, progression, metastasis, and ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/642916
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/859328
更新日期:2014-01-01 00:00:00
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doi:10.1155/2015/241769
更新日期:2015-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2016-01-01 00:00:00
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doi:10.1155/2015/746093
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/256549
更新日期:2013-01-01 00:00:00
abstract::Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conduction inhibitions by l...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/540238
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7196981
更新日期:2020-06-10 00:00:00
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journal_title:BioMed research international
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doi:10.1155/2018/1909410
更新日期:2018-06-28 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4935386
更新日期:2020-02-12 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7856517
更新日期:2018-12-09 00:00:00