Antioxidants as Renoprotective Agents for Ischemia during Partial Nephrectomy.

Abstract:

:Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal artery and veins is often required, which results in transitory ischemia. The renal ischemia-reperfusion injury is associated with increased reactive oxygen species production leading to renal tissue damage. Thus, the use of antioxidants has been advocated in the partial nephrectomy perioperative period. Several antioxidants were investigated in regard to renal ischemia-reperfusion injury. The present manuscript aims to present the literature on the most commonly studied antioxidants used during partial nephrectomy. The results of experimental and clinical studies using antioxidants during partial nephrectomy are reported. Further, alimentary sources of some antioxidants are presented, stimulating future studies focusing on perioperative antioxidant-rich diets.

journal_name

Biomed Res Int

authors

Buys-Gonçalves GF,Abreu LAS,Gregorio BM,Sampaio FJB,Pereira-Sampaio MA,de Souza DB

doi

10.1155/2019/8575398

subject

Has Abstract

pub_date

2019-02-07 00:00:00

pages

8575398

eissn

2314-6133

issn

2314-6141

journal_volume

2019

pub_type

杂志文章,评审
  • Multiple biomarker panels for early detection of breast cancer in peripheral blood.

    abstract::Detecting breast cancer at early stages can be challenging. Traditional mammography and tissue microarray that have been studied for early breast cancer detection and prediction have many drawbacks. Therefore, there is a need for more reliable diagnostic tools for early detection of breast cancer due to a number of fa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/781618

    authors: Zhang F,Deng Y,Drabier R

    更新日期:2013-01-01 00:00:00

  • Extracorporeal Membrane Oxygenation in Cardiogenic Shock due to Acute Myocardial Infarction: A Systematic Review.

    abstract:Background:Cardiogenic shock is associated with high mortality, despite new strategies for reperfusion therapy. Short-term circulatory support devices may provide adequate support for appropriate myocardial and organ perfusion. Objectives:This review is aimed at evaluating the impact on survival when using venoarteria...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/6126534

    authors: Zavalichi MA,Nistor I,Nedelcu AE,Zavalichi SD,Georgescu CMA,Stătescu C,Covic A

    更新日期:2020-04-19 00:00:00

  • Protective Effects of Adiponectin against Cobalt Chloride-Induced Apoptosis of Smooth Muscle Cells via cAMP/PKA Pathway.

    abstract::Adiponectin (APN) is an adipokine secreted from adipose tissue and exhibits biological functions such as microcirculation-regulating, hearing-protective, and antiapoptotic. However, the effect of APN on the apoptosis of spiral arterial smooth muscle cells (SMCs) under hypoxic conditions in vitro is not clear. We used ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/7169348

    authors: Xiao J,Zhang Y,Zhang W,Zhang L,Li L,Si J,Li X,Ma K

    更新日期:2020-10-10 00:00:00

  • Advanced Hemodynamic Management in Patients with Septic Shock.

    abstract::In patients with sepsis and septic shock, the hemodynamic management in both early and later phases of these "organ dysfunction syndromes" is a key therapeutic component. It needs, however, to be differentiated between "early goal-directed therapy" (EGDT) as proposed for the first 6 hours of emergency department treat...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2016/8268569

    authors: Saugel B,Huber W,Nierhaus A,Kluge S,Reuter DA,Wagner JY

    更新日期:2016-01-01 00:00:00

  • Analyzing Active Constituents and Optimal Steaming Conditions Related to the Hematopoietic Effect of Steamed Panax notoginseng by Network Pharmacology Coupled with Response Surface Methodology.

    abstract::During hundreds of years of medication, it is believed that the steamed Panax notoginseng (SPN) can enrich and regulate the blood, replenish the body, and improve the health. The aim of this study was to optimize the steaming conditions of SPN which are related to the hematopoietic effect. In the study, network pharma...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9371426

    authors: Zhou S,Jiang N,Zhang M,Xiao X,Liu Z,Xu X,Gao Q,Lv W

    更新日期:2020-07-26 00:00:00

  • A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease.

    abstract::Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF). Hitherto, the development of consistent, stable, and reproducible models of closed-chest MI in large animals, ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/410631

    authors: Biondi-Zoccai G,De Falco E,Peruzzi M,Cavarretta E,Mancone M,Leoni O,Caristo ME,Lotrionte M,Marullo AG,Amodeo A,Pacini L,Calogero A,Petrozza V,Chimenti I,D'Ascenzo F,Frati G

    更新日期:2013-01-01 00:00:00

  • Diffusion tensor histogram analysis of pediatric diffuse intrinsic pontine glioma.

    abstract:PURPOSE:To evaluate tumor structure in children with diffuse intrinsic pontine glioma (DIPG) using histogram analyses of mean diffusivity (MD), determine potential treatment and corticosteroid-related effects on MD, and monitor changes in MD distributions over time. MATERIALS AND METHODS:DTI was performed on a 1.5T GE...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/647356

    authors: Steffen-Smith EA,Sarlls JE,Pierpaoli C,Shih JH,Bent RS,Walker L,Warren KE

    更新日期:2014-01-01 00:00:00

  • Validation of Reference Genes for Gene Expression Normalization in RAW264.7 Cells under Different Conditions.

    abstract::RAW264.7 is a macrophage strain derived from mice tumour and shows a significant ability in antigen uptake. Real-time quantitative PCR (RT-qPCR) is one of the most commonly used methods in gene studies and requires suitable reference genes to normalize and quantitate the expression of gene of interest with sensitivity...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/6131879

    authors: Bao Z,Huang Y,Chen J,Wang Z,Qian J,Xu J,Zhao Y

    更新日期:2019-05-16 00:00:00

  • Anti-IL-5 and IL-5Ra: Efficacy and Safety of New Therapeutic Strategies in Severe Uncontrolled Asthma.

    abstract::The current developments of the new biological drugs targeting interleukin 5 (IL-5) and IL-5 receptor allowed to expand the treatment options for severe hypereosinophilic asthma. Clinicians will then be able to choose between antibodies targeting either circulating IL-5 or its receptor expressed on eosinophils and bas...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/5698212

    authors: Bagnasco D,Caminati M,Ferrando M,Aloè T,Testino E,Canonica GW,Passalacqua G

    更新日期:2018-11-05 00:00:00

  • Dissociation of Calcium Transients and Force Development following a Change in Stimulation Frequency in Isolated Rabbit Myocardium.

    abstract::As the heart transitions from one exercise intensity to another, changes in cardiac output occur, which are modulated by alterations in force development and calcium handling. Although the steady-state force-calcium relationship at various heart rates is well investigated, regulation of these processes during transiti...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/468548

    authors: Haizlip KM,Milani-Nejad N,Brunello L,Varian KD,Slabaugh JL,Walton SD,Gyorke S,Davis JP,Biesiadecki BJ,Janssen PM

    更新日期:2015-01-01 00:00:00

  • Immunomodulation by Zearalenone in Carp (Cyprinus carpio L.).

    abstract::The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feeds, but its effects on fish have not yet been investigated extensively. In order to fill this gap a feeding trial with juvenile carp was conducted. Three groups of fish were fed feeds contaminated with ZEN at three concentrations (low: 332 μg kg(-1...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/420702

    authors: Pietsch C,Junge R,Burkhardt-Holm P

    更新日期:2015-01-01 00:00:00

  • Call to Action for Nurses/Nursing.

    abstract::The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2016/3127543

    authors: Premji SS,Hatfield J

    更新日期:2016-01-01 00:00:00

  • Links between Vitamin D Deficiency and Cardiovascular Diseases.

    abstract::The aim of the present paper was to review the most important mechanisms explaining the possible association of vitamin D deficiency and cardiovascular diseases, focusing on recent experimental and clinical data. Low vitamin D levels favor atherosclerosis enabling vascular inflammation, endothelial dysfunction, format...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/109275

    authors: Mozos I,Marginean O

    更新日期:2015-01-01 00:00:00

  • Sulfonamide-Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics.

    abstract::A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N2H4 to get aromatic sulfonyl hydrazides 2(a-d). The intermediate hydrazides 2(a-d) were treated with substituted aldehyd...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8104107

    authors: Abas M,Rafique H,Shamas S,Roshan S,Ashraf Z,Iqbal Z,Raza H,Hassan M,Afzal K,Rizvanov AA,Asad MHHB

    更新日期:2020-02-20 00:00:00

  • Yes-Associated Protein 1 as a Novel Prognostic Biomarker for Gastrointestinal Cancer: A Meta-Analysis.

    abstract:Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2018/4039173

    authors: Zhang L,Song X,Li X,Wu C,Jiang J

    更新日期:2018-11-14 00:00:00

  • Adventitial alterations are the main features in pulmonary artery remodeling due to long-term chronic intermittent hypobaric hypoxia in rats.

    abstract::Long-term chronic intermittent exposure to altitude hypoxia is a labor phenomenon requiring further research. Using a rat model, we examined whether this type of exposure differed from chronic exposure in terms of pulmonary artery remodeling and other features. Rats were subjected to chronic hypoxia (CH, n = 9) and lo...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/169841

    authors: Brito J,Siques P,Arribas SM,López de Pablo AL,González MC,Naveas N,Arriaza K,Flores K,León-Velarde F,Pulido R,Ordenes S,López MR

    更新日期:2015-01-01 00:00:00

  • Kidney-targeted transplantation of mesenchymal stem cells by ultrasound-targeted microbubble destruction promotes kidney repair in diabetic nephropathy rats.

    abstract::We test the hypothesis that ultrasound-targeted microbubble destruction (UTMD) technique increases the renoprotective effect of kidney-targeted transplantation of bone-marrow-derived mesenchymal stem cells (BM-MSCs) in diabetic nephropathy (DN) rats. Diabetes was induced by streptozotocin injection (60 mg/Kg, intraper...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/526367

    authors: Zhang Y,Ye C,Wang G,Gao Y,Tan K,Zhuo Z,Liu Z,Xia H,Yang D,Li P

    更新日期:2013-01-01 00:00:00

  • Induction of apoptotic effects of antiproliferative protein from the seeds of Borreria hispida on lung cancer (A549) and cervical cancer (HeLa) cell lines.

    abstract::A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/179836

    authors: Rupachandra S,Sarada DV

    更新日期:2014-01-01 00:00:00

  • Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment.

    abstract::Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/867140

    authors: Jiang C,Shao Q,Jin B,Gong R,Zhang M,Xu B

    更新日期:2015-01-01 00:00:00

  • Seasonal Variation in Essential Oils Composition and the Biological and Pharmaceutical Protective Effects of Mentha longifolia Leaves Grown in Tunisia.

    abstract::This research assessed the seasonal variation of the chemical composition and antibacterial and anticholinesterase activities of essential oils extracted from M. longifolia leaves. The leaves organic fractions were also investigated for their biological activities and pharmacological functions. The essential oil highe...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/7856517

    authors: Zouari-Bouassida K,Trigui M,Makni S,Jlaiel L,Tounsi S

    更新日期:2018-12-09 00:00:00

  • Clinical Usefulness of Immunohistochemical Staining of p57 kip2 for the Differential Diagnosis of Complete Mole.

    abstract:OBJECTIVE:Can polymer-based immunohistochemical staining of p57(kip2) replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? METHODS AND MATERIALS:Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and exami...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/905648

    authors: Sasaki S,Sasaki Y,Kunimura T,Sekizawa A,Kojima Y,Iino K

    更新日期:2015-01-01 00:00:00

  • Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

    abstract::Background and Aims. CIN is a major and serious complication following PCI in patients with ACS. It is unclear whether a higher serum ferritin level is associated with an increased risk of CIN in high-risk patients. Thus, we conducted this study to assess the predictive value of SF for the risk of CIN after PCI. Metho...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/5420345

    authors: Zhu B,Hou J,Gong Y,Yan G,Wang Q,Wang D,Qiao Y,Chen Y,Tang C

    更新日期:2016-01-01 00:00:00

  • Diagnosis and Treatment of Human Salmonellosis in Addis Ababa City, Ethiopia.

    abstract:Background:Diagnosis using reliable tools and treatment following in vitro antimicrobial susceptibility tests are critical to proper addressing of antibiotic-resistant Salmonella infection. Methodology:A cross-sectional study was conducted to assess the practice of diagnosis and treatment of salmonellosis in Addis Aba...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/6406405

    authors: Garedew L,Solomon S,Worku Y,Worku H,Gemeda D,Lelissa G,Mamuye Y,Abubeker R,Mihret A,Fentaw S,Worku A,Bahiru M,Erenso G

    更新日期:2018-05-23 00:00:00

  • The Bewildering Effect of AMPK Activators in Alzheimer's Disease: Review of the Current Evidence.

    abstract::Alzheimer's disease is a multifactorial neurodegenerative disease characterized by progressive cognitive dysfunction. It is the most common form of dementia. The pathologic hallmarks of the disease include extracellular amyloid plaque, intracellular neurofibrillary tangles, and oxidative stress, to mention some of the...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/9895121

    authors: Assefa BT,Tafere GG,Wondafrash DZ,Gidey MT

    更新日期:2020-02-18 00:00:00

  • Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2 Diabetes.

    abstract::We recruited a group of 6713 consecutive Chinese patients with T2D but normal renal and liver function who were admitted to one of 81 top tertiary care hospitals in China. Mild hypoglycaemia was defined as having symptomatic hypoglycaemia in one month before hospitalization. Severe hypoglycaemia was defined as having ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/862896

    authors: Li Y,Mu Y,Ji Q,Huang Q,Kuang H,Ji L,Yang X

    更新日期:2015-01-01 00:00:00

  • The Effects of County Public Hospital Reform on the Consumption and Costs of Antibiotics: Evidence from a Quasinatural Experiment in Jiangsu, China.

    abstract:Background:Overuse of antibiotics is a major driver for rapid spread of antimicrobial resistance worldwide, particularly common in China. The close linkage between hospital revenue and sales of drugs has become the key incentive for overprescription of antibiotics. Since 2009, the Chinese government implemented a serie...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9262170

    authors: Wang Y,Zhu Y,Liu X,Xu X,Fang W,Li X

    更新日期:2020-10-22 00:00:00

  • Validation of an Endoscopic Fibre-Optic Pressure Sensor for Noninvasive Measurement of Variceal Pressure.

    abstract::In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of in vivo and in vitro studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/1893474

    authors: Sun B,Kong DR,Li SW,Yu DF,Wang GJ,Yu FF,Wu Q,Xu JM

    更新日期:2016-01-01 00:00:00

  • MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39.

    abstract::Emerging evidence shows that microRNAs (miRNAs) play important roles in the regulation of various biological and pathologic processes in human cancers and the aberrant expression of miRNAs contributes to the tumor development. In this study, our findings indicate that miR-451 is significantly overexpressed in pancreat...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2381482

    authors: Guo R,Gu J,Zhang Z,Wang Y,Gu C

    更新日期:2017-01-01 00:00:00

  • Predictive contribution of neutrophil/lymphocyte ratio in diagnosis of brucellosis.

    abstract::Here we wanted to investigate predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in the diagnosis of brucellosis. Thirty-two brucellosis patients diagnosed with positive serum agglutination test and thirty-two randomized healthy subjects were enrolled in this study retrospectivel...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/210502

    authors: Olt S,Ergenç H,Açıkgöz SB

    更新日期:2015-01-01 00:00:00

  • A Comparison of Surgical Invasions for Spinal Nerve Ligation with or without Paraspinal Muscle Removal in a Rat Neuropathic Pain Model.

    abstract::L5 spinal nerve ligation (SNL) in rats is one of the most popular models for studying neuropathic pain because of its high reproducibility. During the surgery, a part of the L5 paraspinal muscle is usually removed, which produces extra trauma and may potentially affect the physiological processes involved in neuropath...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/6741295

    authors: Huang YG,Zhang Q,Wu H,Zhang CQ

    更新日期:2016-01-01 00:00:00