A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease.

abstract：:This work aimed to explore the cardiovascular effects induced by freeze-dried juice from Syzygium jambolanum (Lam.) DC fruits (JSJ). JSJ presented high polyphenol content and steroids. HPLC analysis revealed that 2,5-dihydroxybenzoic and caffeic acid were present in higher amounts in the JSJ extract. In rat, JSJ induc...

journal_title：BioMed research international

authors： Assis KS,Araújo IGA,de Azevedo FLAA,Maciel PMP,Machado Calzerra NT,da Silva TAF,Assis VL,de Vasconcelos AP,Santos CAG,Meireles BRLA,Cordeiro AMTM,Araújo DAM,Ribeiro TP,Medeiros IA

更新日期：2018-10-08 00:00:00

abstract：:Recently, cardiovascular disease, also known as loop circulatory system diseases or disorders, is one of the serious diseases including heart disease, stroke, atherosclerosis, myocardial infarction, hypertension, hypotension, and thrombosis. Human pregnane X receptor, PXR, plays a crucial role in exogenous and endobio...

journal_title：BioMed research international

authors： Chen KB,Chen HY,Chen KC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]IPQA derivative as ...

journal_title：BioMed research international

authors： Yeh SH,Lin CF,Kong FL,Wang HE,Hsieh YJ,Gelovani JG,Liu RS

更新日期：2013-01-01 00:00:00

abstract：Background:Existing literature suggests that an association exists between coronary artery disease (CAD) and carpal tunnel syndrome (CTS), but few researchers have explored whether CTS is a risk for CAD. Materials and Methods:This large case-control study explored the association between CTS and CAD, using health insu...

journal_title：BioMed research international

authors： Chang YC,Chiang JH,Lay IS,Lee YC

更新日期：2019-03-03 00:00:00

abstract：:Few studies assess agreement among Schistosoma haematobium eggs, measured hematuria, and self-reported metrics. We assessed agreement among four metrics at a single time point and analyzed the stability of infection across two time points with a single metric. We used data from the Eastern Region of Ghana and construc...

journal_title：BioMed research international

authors： Kosinski KC,Kulinkina AV,Tybor D,Osabutey D,Bosompem KM,Naumova EN

更新日期：2016-01-01 00:00:00

abstract：:Stem cell-based therapy has been considered as a promising option in the treatment of ischemic heart disease. Although stem cell administration resulted in the temporary improvement of myocardial contractility in the majority of studies, the formation of new cardiomyocytes within the injured myocardium has not been co...

journal_title：BioMed research international

authors： Belostotskaya G,Hendrikx M,Galagudza M,Suchkov S

更新日期：2020-03-03 00:00:00

abstract：:Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane h...

journal_title：BioMed research international

authors： Gabarre S,Herrera A,Mateo J,Ibarz E,Lobo-Escolar A,Gracia L

更新日期：2014-01-01 00:00:00

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：:Patients with left ventricle (LV) volume overload (VO) remain in a compensated state for many years although severe dilation is present. The myocardial capacity to fulfill its energetic demand may delay decompensation. We performed a gene expression profile, a model of chronic VO in rat LV with severe aortic valve reg...

journal_title：BioMed research international

authors： Roussel E,Drolet MC,Walsh-Wilkinson E,Dhahri W,Lachance D,Gascon S,Sarrhini O,Rousseau JA,Lecomte R,Couet J,Arsenault M

更新日期：2015-01-01 00:00:00

abstract：:Polyetheretherketone (PEEK), which has biomechanical performance similar to that of human cancellous bone, is used widely as a spinal implant material. However, its bioinertness and hydrophobic surface properties result in poor osseointegration. This study applies a novel modification method, arc ion plating (AIP), th...

journal_title：BioMed research international

authors： Tsou HK,Chi MH,Hung YW,Chung CJ,He JL

更新日期：2015-01-01 00:00:00

abstract：Background and Aim:Lubiprostone is a novel laxative that sometimes causes nausea, but preventive strategies remain unconfirmed. Methods:We retrospectively chose 126 patients prescribed lubiprostone from 2013 to 2016. Medical records were reviewed to clarify whether nausea developed after administration of the drug. Ba...

journal_title：BioMed research international

authors： Yamamoto T,Osumi S,Yanagisawa D,Yamato H,Aoyagi H,Isono A,Abe K,Kita H

更新日期：2017-01-01 00:00:00

abstract：Objective:Epidemiological studies have shown a correlation between periodontal disease (PD) and age-related macular degeneration (AMD). However, the results have been inconsistent, and no relevant meta-analysis has been performed on this topic. Hence, we performed a meta-analysis to evaluate whether the two diseases ar...

journal_title：BioMed research international

authors： Lv X,Li W,Fang Z,Xue X,Pan C

更新日期：2020-09-28 00:00:00

abstract：:WHO reported that adherence among patients with chronic diseases averages only 50% in developed countries. This is recognized as a significant public health issue, since medication nonadherence leads to poor health outcomes and increased healthcare costs. Improving medication adherence is, therefore, crucial and revea...

journal_title：BioMed research international

authors： Lam WY,Fresco P

更新日期：2015-01-01 00:00:00

abstract：:The expression profile of long noncoding RNA (lncRNA) in human epicardial adipose tissue (EAT) has not been widely studied. In the present study, we performed RNA sequencing to analyze the expression profiles of lncRNA and mRNA in EAT in coronary artery disease (CAD) patients with and without heart failure (HF). Our r...

journal_title：BioMed research international

authors： Zheng M,Zhao L,Yang X

更新日期：2019-07-04 00:00:00

abstract：:A dentin-cement-prosthesis complex restored with either all-porcelain, cured resin-composite, or cast base metal alloy and cemented with either of the different resin cements was trimmed into a mini-dumbbell shape for tensile testing. The fractured surfaces and characterization of the dentin-cement interface of bonded...

journal_title：BioMed research international

authors： Piemjai M,Nakabayashi N

更新日期：2015-01-01 00:00:00

abstract：:Black stain is characterized as a dark line or an incomplete coalescence of dark dots localized on the cervical third of the tooth. Over the last century, the etiology of black stain has been the subject of much debate. Most of the studies concerning this issue were conducted in pediatric population. According to the ...

journal_title：BioMed research international

authors： Żyła T,Kawala B,Antoszewska-Smith J,Kawala M

更新日期：2015-01-01 00:00:00

abstract：Background:Cardiogenic shock is associated with high mortality, despite new strategies for reperfusion therapy. Short-term circulatory support devices may provide adequate support for appropriate myocardial and organ perfusion. Objectives:This review is aimed at evaluating the impact on survival when using venoarteria...

journal_title：BioMed research international

authors： Zavalichi MA,Nistor I,Nedelcu AE,Zavalichi SD,Georgescu CMA,Stătescu C,Covic A

更新日期：2020-04-19 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:Diabetes mellitus is a disease which has affected 415 million patients in 2015. In an effort to replace the significant demands on transplantation and morbidity associated with transplantation, the production of β-like cells differentiated from induced pluripotent stem cells (iPSCs) was evaluated. This approach is ass...

journal_title：BioMed research international

authors： Wan J,Huang Y,Zhou P,Guo Y,Wu C,Zhu S,Wang Y,Wang L,Lu Y,Wang Z

更新日期：2017-01-01 00:00:00

abstract：:Blood pressure is the most important, modifiable risk factor for cardiovascular diseases. Lifestyle factors and also workload are the main, potential risk factors for the development of hypertension. This study focused on the early detection of unknown hypertension by screening employees in the hotel and restaurant in...

journal_title：BioMed research international

authors： Seibt R,Hunger B,Stieler L,Stoll R,Kreuzfeld S

更新日期：2018-04-08 00:00:00

abstract：Objectives:This study aims to determine the changing in hip anatomy parameters with age and reveals the reason for the extorsion of lower extremity in the aged. Design:Retrospective study. Participants:One hundred and forty patients who had received imaging check of the femur and acetabulum between October 2013 and O...

journal_title：BioMed research international

authors： Yin Y,Zhang R,Jin L,Li S,Hou Z,Zhang Y

更新日期：2018-09-27 00:00:00

abstract：:A cross-sectional study was carried out to determine the arsenic (As) and cadmium (Cd) concentrations in blood, urine, and drinking water as well as the health implications on 100 residents in an urban and a rural community. Results showed the blood As, urinary Cd, DNA damage, and water As and Cs were significantly (P...

journal_title：BioMed research international

authors： Zailina H,Najibah H,Aiezzati AN,Praveena SM,Patimah I

更新日期：2014-01-01 00:00:00

abstract：:The application of chemotherapeutic drug adriamycin (ADR) in cancer therapy is limited by its side effects like high toxicity and insolubility. Nanomedicine offers new hope for overcoming the shortcomings. But how to increase in vivo stability and to control intracellular drug release is a key issue for nano-based for...

journal_title：BioMed research international

authors： Chen L,Chen F,Zhao M,Zhu X,Ke C,Yu J,Yan Z,Zhang F,Sun Y,Chen D,Jiang C,Zhao X,Gao Y,Guo S,Li W

更新日期：2015-01-01 00:00:00

abstract：:We aimed to predict the ten-year cardiovascular disease (CVD) risk among low-income urban dwellers of metropolitan Malaysia. Participants were selected from a cross-sectional survey conducted in Kuala Lumpur. To assess the 10-year CVD risk, we employed the Framingham risk scoring (FRS) models. Significant determinants...

journal_title：BioMed research international

authors： Su TT,Amiri M,Mohd Hairi F,Thangiah N,Bulgiba A,Majid HA

更新日期：2015-01-01 00:00:00

abstract：:Ultrasonography has been widely employed to estimate the morphological changes of muscle during contraction. To further investigate the motion pattern of quadriceps during isometric knee extensions, we studied the relative motion pattern between femur and quadriceps under ultrasonography. An interesting observation is...

journal_title：BioMed research international

authors： Zhang S,Huang W,Zeng Y,Shi W,Diao X,Wei X,Ling S

更新日期：2018-03-18 00:00:00

abstract：:Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamella...

journal_title：BioMed research international

authors： Liu Y,Ji M,Wong MK,Joo KI,Wang P

更新日期：2013-01-01 00:00:00

abstract：:Contrast enhanced magnetic resonance imaging (CE-MRI) has acquired a central role in the field of diagnosis and evaluation of breast cancer due to its high sensitivity; on the other hand, MRI has shown a variable specificity because of the wide overlap between the imaging features of benign and malignant lesions. Ther...

journal_title：BioMed research international

authors： Mazzei MA,Di Giacomo L,Fausto A,Gentili F,Mazzei FG,Volterrani L

更新日期：2018-10-21 00:00:00

abstract：:The acute toxicity, the antioxidant activity, and the pharmacological activity on the gastrointestinal tract of rodents of the ethanolic extract (TFEE) from the bark of Terminalia fagifolia Mart. & Zucc. (Combretaceae) and of its aqueous (TFAqF), hydroalcoholic (TFHAF), and hexanic (TFHEXF) partition fractions have be...

journal_title：BioMed research international

authors： Nunes PH,Martins Mdo C,Oliveira Rde C,Chaves MH,Sousa EA,Leite JR,Véras LM,Almeida FR

更新日期：2014-01-01 00:00:00

abstract：Introduction:The purpose of this study was to investigate the difference in surgical outcomes between symptomatic and asymptomatic patients with primary hyperparathyroidism (PHPT) and between patients with high serum calcium and those with normal blood calcium, as well as to explore the epidemiological trend of PHPT in...

journal_title：BioMed research international

authors： Yu Q,Liu K,Ma D,Xie C,Wu Y,Dai W,Jiang H

更新日期：2019-07-01 00:00:00

abstract：:Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs are bound to conforma...

journal_title：BioMed research international

authors： Hu WG,Yin J,Chau D,Hu CC,Lillico D,Yu J,Negrych LM,Cherwonogrodzky JW

更新日期：2013-01-01 00:00:00