Facial vibrotactile stimulation activates the parasympathetic nervous system: study of salivary secretion, heart rate, pupillary reflex, and functional near-infrared spectroscopy activity.

abstract：Purpose:To study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats. Methods:A high-fat diet (HF) was given to 28 rats and 28 ...

journal_title：BioMed research international

authors： Stygar D,Pigłowski W,Chełmecka E,Skrzep-Poloczek B,Sawczyn T,Garłowski W,Jochem J,Karcz KW

更新日期：2018-08-16 00:00:00

abstract：:This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages (pH 4.6, 150 mM lactic acid, aw = 0.92, temperature = 20 or 27°C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inacti...

journal_title：BioMed research international

authors： Lindqvist R,Barmark G

更新日期：2014-01-01 00:00:00

abstract：:Finding an optimal set of discriminative features is still a crucial but challenging task in biomedical science. The complexity of the task is intensified when any of the two scenarios arise: a highly dimensioned dataset and a small sample-sized dataset. The first scenario poses a big challenge to existing machine lea...

journal_title：BioMed research international

authors： Segera D,Mbuthia M,Nyete A

更新日期：2020-08-17 00:00:00

abstract：OBJECTIVE:There is an unmet need for a specific cardiovascular risk (CV) algorithm for rheumatoid arthritis (RA) patients. Lipoprotein data are often not available in RA cohorts but could be obtained from frozen blood samples. The objective of this study was to estimate the storage effect on lipoproteins in long-term (...

journal_title：BioMed research international

authors： Arts EE,Popa CD,Smith JP,Arntz OJ,van de Loo FA,Donders R,Semb AG,Kitas GD,van Riel PL,Fransen J

更新日期：2014-01-01 00:00:00

abstract：Background:Lung cancer is the leading cause of death worldwide. The treatment choice for advanced stage of lung cancer may depend on histotype, performance status (PS), age, and comorbidities. In the present study, we focused on the effect of metronomic vinorelbine treatment in elderly patients with advanced unresectab...

journal_title：BioMed research international

authors： D'Ascanio M,Pezzuto A,Fiorentino C,Sposato B,Bruno P,Grieco A,Mancini R,Ricci A

更新日期：2018-08-27 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:An elevated neutrophil-to-lymphocyte ratio (NLR) has been suggested to be associated with a poor prognosis in several cancers. We evaluated the utility of an elevated NLR as a biomarker to predict the prognosis of metastatic castration-resistant prostate cancer (mCRPC) patients treated with ...

journal_title：BioMed research international

authors： Uemura K,Kawahara T,Yamashita D,Jikuya R,Abe K,Tatenuma T,Yokomizo Y,Izumi K,Teranishi JI,Makiyama K,Yumura Y,Kishida T,Udagawa K,Kobayashi K,Miyoshi Y,Yao M,Uemura H

更新日期：2017-01-01 00:00:00

abstract：Objective:The aim of this study is to explore the potential pathogenesis of juvenile dermatomyositis by bioinformatics analysis of gene chips, which would screen the hub genes, identify potential biomarkers, and reveal the development mechanism of juvenile dermatomyositis. Material and Methods:We retrieved juvenile de...

journal_title：BioMed research international

authors： Qiu CC,Su QS,Zhu SY,Liu RC

更新日期：2019-12-07 00:00:00

abstract：Background:Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underlying biological mechan...

journal_title：BioMed research international

authors： Sekiguchi N,Nomoto J,Nagata A,Kiyota M,Fukuda I,Yamada K,Takezako N,Kobayashi Y

更新日期：2018-10-04 00:00:00

abstract：:After decades of intensive searching for antimicrobial compounds derived from actinobacteria, the frequency of isolation of new molecules has decreased. To cope with this concern, studies have focused on the exploitation of actinobacteria from unexplored environments and actinobacteria symbionts of plants and animals....

journal_title：BioMed research international

authors： Mendes TD,Borges WS,Rodrigues A,Solomon SE,Vieira PC,Duarte MC,Pagnocca FC

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To explore the safety and efficacy of transpseudarthrosis osteotomy with interbody fusion in the treatment of Ankylosing Spondylitis (AS) patients with kyphotic spinal pseudarthrosis by a single posterior approach. METHODS:Twelve consecutive patients with spinal pseudarthrosis underwent transpseudarthrosis o...

journal_title：BioMed research international

authors： Yang E,Cao L,Zhang G,Lian X,Xu J

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Foreign object ingestion and food bolus impaction are a common clinical problem. We report our clinical experiences in endoscopic management for adults, foreign body ingestion, and food bolus impaction. METHOD:A retrospective chart review study was conducted on adult patients with foreign body ingestion and...

journal_title：BioMed research international

authors： Yao CC,Wu IT,Lu LS,Lin SC,Liang CM,Kuo YH,Yang SC,Wu CK,Wang HM,Kuo CH,Chiou SS,Wu KL,Chiu YC,Chuah SK,Tai WC

更新日期：2015-01-01 00:00:00

abstract：:Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, researches on the deve...

journal_title：BioMed research international

authors： Ding X,Liu TD,Xie ZL,Zhao Q,Cao Y,Liu XD,Wang CH,Gamariel RR,Ming X,Li ZY,Kong Y

更新日期：2016-01-01 00:00:00

abstract：:Heart disease is the leading cause of death worldwide. Therefore, assessing the risk of its occurrence is a crucial step in predicting serious cardiac events. Identifying heart disease risk factors and tracking their progression is a preliminary step in heart disease risk assessment. A large number of studies have rep...

journal_title：BioMed research international

authors： Jonnagaddala J,Liaw ST,Ray P,Kumar M,Dai HJ,Hsu CY

更新日期：2015-01-01 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：:Gender affirmation surgery remains one of the greatest challenges in transgender medicine. In recent years, there have been continuous discussions on bioethical aspects in the treatment of persons with gender dysphoria. Gender reassignment is a difficult process, including not only hormonal treatment with possible sur...

journal_title：BioMed research international

authors： Bizic MR,Jeftovic M,Pusica S,Stojanovic B,Duisin D,Vujovic S,Rakic V,Djordjevic ML

更新日期：2018-06-13 00:00:00

abstract：:(124)Iodine ((124)I) with its 4.2 d half-life is particularly attractive for in vivo detection and quantification of longer-term biological and physiological processes; the long half-life of (124)I is especially suited for prolonged time in vivo studies of high molecular weight compounds uptake. Numerous small molecul...

journal_title：BioMed research international

authors： Cascini GL,Niccoli Asabella A,Notaristefano A,Restuccia A,Ferrari C,Rubini D,Altini C,Rubini G

更新日期：2014-01-01 00:00:00

abstract：:Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmis...

journal_title：BioMed research international

authors： Reis Machado J,da Silva MV,Cavellani CL,dos Reis MA,Monteiro ML,Teixeira Vde P,Miranda Corrêa RR

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the shear displacement between the body and backrest/seat, range of motion (ROM), and force acting on the lower limb joints during sit-stand-sit transitions by operating an electric-powered standing wheelchair. METHODS AND MATERIALS:The amounts of sliding along the backrest and ...

journal_title：BioMed research international

authors： Yang YS,Chen MD,Fang WC,Chang JJ,Kuo CC

更新日期：2014-01-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is a very aggressive malignant type of tumor that currently lacks effective targeted therapies. In hematological malignancies, chimeric antigen receptor T (CAR-T) cells have shown very significant antitumor ability; however, in solid tumors, the efficacy is poor. In order to apply ...

journal_title：BioMed research international

authors： Zhao Z,Li Y,Liu W,Li X

更新日期：2020-01-02 00:00:00

abstract：:We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

journal_title：BioMed research international

authors： Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

更新日期：2015-01-01 00:00:00

abstract：:Epidemiological studies have proven an association between consumption of polyphenols and prevention of Alzheimer's disease, the most common form of dementia characterized by extracellular deposition of amyloid beta plaques. The aim of this study is pharmacological screening of the aqueous alcohol extract of Markhamia...

journal_title：BioMed research international

authors： Hassaan Y,Handoussa H,El-Khatib AH,Linscheid MW,El Sayed N,Ayoub N

更新日期：2014-01-01 00:00:00

abstract：:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia f...

journal_title：BioMed research international

authors： Haufe T,Förch S,Müller P,Plath J,Mayr E

更新日期：2016-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00

abstract：PURPOSE:To determine interfractional changes of lung tumor centroid position and tumor regression during stereotactic body radiation therapy (SBRT). METHODS AND MATERIALS:34 patients were treated by SBRT in 4-5 fractions to a median dose of 50 Gy. The CT scans acquired for verification were registered with simulation ...

journal_title：BioMed research international

authors： Sun Y,Lu Y,Cheng S,Guo W,Ye K,Zhao H,Zheng X,Li D,Wang S,Yang C,Ge H

更新日期：2014-01-01 00:00:00

abstract：Background:We investigated the potential safety of remimazolam and propofol in malignant hyperthermia- (HM-) susceptible patients using ryanodine receptor 1- (RYR1-) expressing human embryonic kidney- (HEK-) 293 cells. Methods:We compared the enhanced responsiveness of HEK-293 cells expressing wild-type RYR1 with that...

journal_title：BioMed research international

authors： Watanabe T,Miyoshi H,Noda Y,Narasaki S,Morio A,Toyota Y,Kimura H,Mukaida K,Yasuda T,Tsutsumi YM

更新日期：2021-01-04 00:00:00

abstract：:New and innovative treatment strategies for cancer patients in the fields of immunotherapy and radiotherapy are rapidly developing in parallel. Among the most promising preclinical treatment approaches is combining immunotherapy with radiotherapy where early data suggest synergistic effects in several tumor model syst...

journal_title：BioMed research international

authors： Zeng J,Harris TJ,Lim M,Drake CG,Tran PT

更新日期：2013-01-01 00:00:00

abstract：:Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Emba...

journal_title：BioMed research international

authors： Song X,Qu H,Yang Z,Rong J,Cai W,Zhou H

更新日期：2017-01-01 00:00:00

abstract：Background and Aim:Lubiprostone is a novel laxative that sometimes causes nausea, but preventive strategies remain unconfirmed. Methods:We retrospectively chose 126 patients prescribed lubiprostone from 2013 to 2016. Medical records were reviewed to clarify whether nausea developed after administration of the drug. Ba...

journal_title：BioMed research international

authors： Yamamoto T,Osumi S,Yanagisawa D,Yamato H,Aoyagi H,Isono A,Abe K,Kita H

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditio...

journal_title：BioMed research international

authors： Jacobs JL,Marcus RL,Morrell G,LaStayo P

更新日期：2014-01-01 00:00:00

abstract：:In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...

journal_title：BioMed research international

authors： Rizzo L,Attanasio M,Pinzone MR,Berretta M,Malaguarnera M,Morra A,L'Abbate L,Balestreri L,Nunnari G,Cacopardo B

更新日期：2014-01-01 00:00:00