Engineered IL-7 Receptor Enhances the Therapeutic Effect of AXL-CAR-T Cells on Triple-Negative Breast Cancer.

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：:Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evi...

journal_title：BioMed research international

authors： Vlahos NF,Theodoridis TD,Partsinevelos GA

更新日期：2017-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (AI) and increased cardiovascular risk (CVR). Patients with AI receive glucocorticoid (GC) replacement therapy which can lead to varying levels of blood cortisol. It was s...

journal_title：BioMed research international

authors： Rahvar AH,Haas CS,Danneberg S,Harbeck B

更新日期：2017-01-01 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Parents' birth weight acts as a predictor for the descendant birth weight, with the correlation more strongly transmitted through maternal line. The present research aims to study the correlation between the child's low or increased birth weight, the mother's birth weight, and maternal conditi...

journal_title：BioMed research international

authors： Costa e Silva LI,Gomes FM,Valente MH,Escobar AM,Brentani AV,Grisi SJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:We performed a retrospective study to assess whether the initial molecular characteristics of glioblastomas (GBMs) were associated with the response to the bevacizumab/irinotecan chemotherapy regimen given at recurrence. RESULTS:Comparison of the genomic and gene expression profiles of the responders (n = 1...

journal_title：BioMed research international

authors： Laffaire J,Di Stefano AL,Chinot O,Idbaih A,Gallego Perez-Larraya J,Marie Y,Vintonenko N,Boisselier B,Farina P,Delattre JY,Figarella-Branger D,Honnorat J,Sanson M,Ducray F

更新日期：2014-01-01 00:00:00

abstract：Introduction:To investigate the clinical results of arthroscopic management for the unstable inferior leaf of the lateral meniscus anterior horn and associated cysts through an inframeniscal portal. Methods:From March 2005 to October 2014, 64 patients with an unstable inferior leaf of the lateral meniscus anterior hor...

journal_title：BioMed research international

authors： Chen D,Li Q,Sun Y,Qin J,Yao Y,Jiang Q

更新日期：2017-01-01 00:00:00

abstract：:Bovine pericardium is used for heart valve leaflet replacement where the strength and thinness are critical properties. Pericardium from neonatal animals (4-7 days old) is advantageously thinner and is considered as an alternative to that from adult animals. Here, the structures of adult and neonatal bovine pericardiu...

journal_title：BioMed research international

authors： Sizeland KH,Wells HC,Higgins J,Cunanan CM,Kirby N,Hawley A,Mudie ST,Haverkamp RG

更新日期：2014-01-01 00:00:00

abstract：Introduction:An increased number of survivors have emerged from the 2014 West African Ebola Virus Disease (EVD) epidemic. Post-Ebola Syndrome (PES) is a group of physical and psychological symptoms affecting EVD survivors. This study aimed to estimate the prevalence of PES among EVD survivors in Montserrado County, Lib...

journal_title：BioMed research international

authors： Wilson HW,Amo-Addae M,Kenu E,Ilesanmi OS,Ameme DK,Sackey SO

更新日期：2018-06-28 00:00:00

abstract：Background:In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. Methods and Results:This pilot study (n=48) compared plasma levels of corin, neprilysin, ...

journal_title：BioMed research international

authors： Zaidi SS,Ward RD,Ramanathan K,Yu X,Gladysheva IP,Reed GL

更新日期：2018-07-26 00:00:00

abstract：:Metabolic syndrome (MetS) is a steering force for the cardiovascular diseases epidemic in Asia. This study aimed to compare the prevalence of MetS in Malaysian adults using NCEP-ATP III, IDF, and JIS definitions, identify the demographic factors associated with MetS, and determine the level of agreement between these ...

journal_title：BioMed research international

authors： Ramli AS,Daher AM,Nor-Ashikin MN,Mat-Nasir N,Ng KK,Miskan M,Ambigga KS,Ariffin F,Mazapuspavina MY,Abdul-Razak S,Abdul-Hamid H,Abd-Majid F,Abu-Bakar N,Nawawi H,Yusoff K

更新日期：2013-01-01 00:00:00

abstract：:Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, c...

journal_title：BioMed research international

authors： Fanos V,Atzori L,Makarenko K,Melis GB,Ferrazzi E

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study is to investigate the changes in QT, QTc, and Tp-e intervals and Tp-e/QT ratio on surface electrocardiogram (ECG) signals during anaesthesia induction using propofol or sevoflurane after preoperative cefuroxime infusion. Some 120 cases of gynaecological patients are randomly divided into propofol...

journal_title：BioMed research international

authors： Liu Y,Gao H,Wang G,An L,Yi J,Fu X,Wen C,Wang Z

更新日期：2019-01-02 00:00:00

abstract：Background:Overuse of antibiotics is a major driver for rapid spread of antimicrobial resistance worldwide, particularly common in China. The close linkage between hospital revenue and sales of drugs has become the key incentive for overprescription of antibiotics. Since 2009, the Chinese government implemented a serie...

journal_title：BioMed research international

authors： Wang Y,Zhu Y,Liu X,Xu X,Fang W,Li X

更新日期：2020-10-22 00:00:00

abstract：:Persistent catecholamine-resistant shock in children causes severe morbidity and mortality. We aimed to analyze the association between hemodynamics and serum lactate at different time points and 28-day mortality in children with persistent catecholamine-resistant shock. Methods. Twenty-six children with persistent ca...

journal_title：BioMed research international

authors： Lee EP,Chu SC,Hsia SH,Chen KF,Chan OW,Lin CY,Su YT,Lin JJ,Wu HP

更新日期：2020-06-19 00:00:00

abstract：:The present study was designed to evaluate the cardioprotective effect of sesamol against doxorubicin-induced cardiomyopathy in rats. In this study, the cardioprotective effect of sesamol against doxorubicin induced cardiomyopathy in experimental rats was evaluated at the dosage of 50 mg/kg bw. Doxorubicin was adminis...

journal_title：BioMed research international

authors： Chennuru A,Saleem MT

更新日期：2013-01-01 00:00:00

abstract：:Interest is rising for animal modeling of pathological gambling. Using the operant probabilistic-delivery task (PDT), gambling proneness can be evaluated in laboratory animals. Drawing a comparison with rats, this study evaluated the common marmoset (Callithrix jacchus) using a PDT. By nose- or hand-poking, subjects l...

journal_title：BioMed research international

authors： Zoratto F,Sinclair E,Manciocco A,Vitale A,Laviola G,Adriani W

更新日期：2014-01-01 00:00:00

abstract：:Diarrhea is a major clinical problem affecting foals up to 3 months of age. The aim of this study was to identify enteric microorganisms involved in monoinfections and coinfections and the associated virulence factors in healthy and diarrheic foals. Diarrheic (D) (n = 56) and nondiarrheic (ND) foals (n = 60) up to thr...

journal_title：BioMed research international

authors： Olivo G,Lucas TM,Borges AS,Silva RO,Lobato FC,Siqueira AK,da Silva Leite D,Brandão PE,Gregori F,de Oliveira-Filho JP,Takai S,Ribeiro MG

更新日期：2016-01-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) has a significant clinical relevance of being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available targeted agents. Increased aggressiveness of this tumor, as well as resistance to standard drug therapies, may be as...

journal_title：BioMed research international

authors： Collina F,Di Bonito M,Li Bergolis V,De Laurentiis M,Vitagliano C,Cerrone M,Nuzzo F,Cantile M,Botti G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Can polymer-based immunohistochemical staining of p57(kip2) replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? METHODS AND MATERIALS:Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and exami...

journal_title：BioMed research international

authors： Sasaki S,Sasaki Y,Kunimura T,Sekizawa A,Kojima Y,Iino K

更新日期：2015-01-01 00:00:00

abstract：:Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...

journal_title：BioMed research international

authors： Bit A,Ghagare D,Rizvanov AA,Chattopadhyay H

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Inflammation in dental pulp cells (DPCs) initiated by Lipopolysaccharide (LPS) results in dental pulp necrosis. So far, whether there is a common system regulating inflammation response and tissue regeneration remains unknown. miR-146a is closely related to inflammation. Basic fibroblast growth factor (bFG...

journal_title：BioMed research international

authors： Liu L,Shu S,Cheung GS,Wei X

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:There is a paucity of a biological large animal model of myocardial infarction (MI). We hypothesized that, using autologous-aggregated platelets, we could create an ovine model that was reproducible and more closely mimicked the pathophysiology of MI. METHODS:Mepacrine stained autologous platelets from male ...

journal_title：BioMed research international

authors： Spata T,Bobek D,Whitson BA,Parthasarathy S,Mohler PJ,Higgins RS,Kilic A

更新日期：2013-01-01 00:00:00

abstract：:Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 (EZR-AS1) is associated with the progression of coronary heart disease (CHD) remains unclear. Accordingly, the aim of th...

journal_title：BioMed research international

authors： You G,Long X,Song F,Huang J,Tian M,Xiao Y,Deng S,Wu Q

更新日期：2020-05-22 00:00:00

abstract：:Graphene is the first 2-dimensional material and possesses a plethora of original properties. Graphene and its derivatives have exhibited a great potential in a number of fields, both medical and nonmedical. The aim of this review is to set the theoretical basis for further research in developing graphene-based endova...

journal_title：BioMed research international

authors： Patelis N,Moris D,Matheiken S,Klonaris C

更新日期：2016-01-01 00:00:00

abstract：:In vitro research performed on eukaryotic or prokaryotic cell cultures usually represents the initial step for characterization of a novel photosensitizer (PS) intended for application in photodynamic therapy (PDT) of cancer or photodynamic inactivation (PDI) of microorganisms. Although many experimental steps of PS t...

journal_title：BioMed research international

authors： Kiesslich T,Gollmer A,Maisch T,Berneburg M,Plaetzer K

更新日期：2013-01-01 00:00:00

abstract：:Postoperative surgical site infections (SSIs) are more common complications after spinal surgery. SSIs often require extended hospitalisation and may worsen overall clinical outcomes. A retrospective database review of consecutive patients with traditional open lumbar spinal surgery was performed. SSIs patients were i...

journal_title：BioMed research international

authors： Liu JT,Liao WJ,Chang CS,Chen YH

更新日期：2015-01-01 00:00:00

abstract：:Asthma susceptibility genes are mapped to a region on human chromosome 5q31-q33, which contains a cluster of proinflammatory cytokine genes such as interleukin-13 (IL-13), which is associated with asthma. This study investigated the allele frequencies of two single nucleotide polymorphisms (SNPs) (-1111C>T and 4257C>A...

journal_title：BioMed research international

authors： Radhakrishnan AK,Raj VL,Tan LK,Liam CK

更新日期：2013-01-01 00:00:00

abstract：Background:The aim of this study was to assess changes in skin microbiota of wrestlers during training sessions and to determine the sensitivity of hemolytic bacterial isolates to antiseptics. Methods:The main skin bacterial isolates obtained from the skin of 15 wrestlers were identified by cultivation method, with th...

journal_title：BioMed research international

authors： Martykanova DS,Davletova NC,Zemlenuhin IA,Volchkova VI,Mugallimov SM,Ahatov AM,Laikov AV,Markelova MI,Boulygina EA,Lopukhov LV,Grigoryeva TV

更新日期：2019-01-10 00:00:00

abstract：AIM:To create a predictive score for the discrimination between benign and malignant parotid tumors using elastographic parameters and to compare its sensitivity and specificity with standard ultrasound. METHODS:A total of 124 patients with parotid gland lesions for whom surgery was planned were examined using convent...

journal_title：BioMed research international

authors： Heřman J,Sedláčková Z,Vachutka J,Fürst T,Salzman R,Vomáčka J,Heřman M

更新日期：2017-01-01 00:00:00