A comprehensive tutorial on in vitro characterization of new photosensitizers for photodynamic antitumor therapy and photodynamic inactivation of microorganisms.

abstract：:The aging process causes a number of changes in the skin, including oxidative stress and dyschromia. The kojic acid (KA) is iron chelator employed in treatment of skin aging, and inhibits tyrosinase, promotes depigmentation. Nanotechnology-based drug delivery systems, such as liquid crystalline systems (LCSs), can mod...

journal_title：BioMed research international

authors： Gonçalez ML,Corrêa MA,Chorilli M

更新日期：2013-01-01 00:00:00

abstract：:Neem (Azadirachta indica A. Juss) oil (NO) was assayed against forty-eight isolates of Escherichia coli by standardised disc diffusion test and microdilution test. By molecular biology characterization, fourteen isolates resulted in diarrheagenic E. coli with sixteen primer pairs that specifically amplify unique seque...

journal_title：BioMed research international

authors： Del Serrone P,Toniolo C,Nicoletti M

更新日期：2015-01-01 00:00:00

abstract：:It is well known that D-glucosamine hydrochloride (DGL) has a variety of biological activities and is regarded as a nutritional supplement effective in improving various disorders, including osteoarthritis and atherosclerosis. Although it has been reported that DGL has a significant pain relief effect in treating oste...

journal_title：BioMed research international

authors： Kaida K,Yamashita H,Toda K,Hayashi Y

更新日期：2014-01-01 00:00:00

abstract：:Accumulating evidence reveals that the sirtuin family is involved in the pathology of Parkinson's disease (PD). However, the association between the polymorphisms of the sirtuin gene and the risk of PD remains elusive. Here, we investigated the possible association of nine SIRT1 and SIRT2 SNPs with the risk of PD thro...

journal_title：BioMed research international

authors： Chen X,Mai H,Chen X,Cai Y,Cheng Q,Chen X,Li X,Fan W,Tang P,Ou M,Yang J,Chen Y,Cui L

更新日期：2019-05-12 00:00:00

abstract：:A large number of occupational exposure limit values (OELs) are based on avoiding of sensory irritation of the eyes and the upper respiratory tract. In order to investigate the chemosensory effect range of a chemical, odor and sensory irritation thresholds (lateralization thresholds, LTs) can be assessed. Humidity aff...

journal_title：BioMed research international

authors： Monsé C,Sucker K,Hoffmeyer F,Jettkant B,Berresheim H,Bünger J,Brüning T

更新日期：2016-01-01 00:00:00

abstract：:A new fungus Cladosporium oxysporum GQ-3 producing extracellular xylanase was isolated from decaying agricultural waste and identified based on the morphology and comparison of internal transcribed spacer (ITS) rDNA gene sequence. C. oxysporum produced maximum xylanase activity of 55.92 U/mL with wheat bran as a subst...

journal_title：BioMed research international

authors： Guan GQ,Zhao PX,Zhao J,Wang MJ,Huo SH,Cui FJ,Jiang JX

更新日期：2016-01-01 00:00:00

abstract：:Background. It has been suggested that, during pregnancy, endometriosis can cause a variety of disease-related complications. Objectives. The purpose of the study was to find out if women with histologically confirmed endometriosis do have a higher risk of adverse pregnancy outcome and if they suffer from a higher rat...

journal_title：BioMed research international

authors： Allerstorfer C,Oppelt P,Enzelsberger SH,Shamiyeh A,Schimetta W,Shebl OJ,Mayer RB

更新日期：2016-01-01 00:00:00

abstract：:This study was performed to assess the efficacy and safety of a topical diclofenac solution in patients with knee osteoarthritis (OA). PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched for randomized controlled trials until June 2020. The WOMAC pain, stiffness, physical function subs...

journal_title：BioMed research international

authors： Ling T,Li JJ,Xu RJ,Wang B,Ge WH

更新日期：2020-11-24 00:00:00

abstract：:Cabbages (Brassica oleracea L.) are an important vegetable crop around world, and cold temperature is among the most significant abiotic stresses causing agricultural losses, especially in cabbage crops. Plant bZIP transcription factors play diverse roles in biotic/abiotic stress responses. In this study, 119 putative...

journal_title：BioMed research international

authors： Hwang I,Manoharan RK,Kang JG,Chung MY,Kim YW,Nou IS

更新日期：2016-01-01 00:00:00

abstract：:We recruited a group of 6713 consecutive Chinese patients with T2D but normal renal and liver function who were admitted to one of 81 top tertiary care hospitals in China. Mild hypoglycaemia was defined as having symptomatic hypoglycaemia in one month before hospitalization. Severe hypoglycaemia was defined as having ...

journal_title：BioMed research international

authors： Li Y,Mu Y,Ji Q,Huang Q,Kuang H,Ji L,Yang X

更新日期：2015-01-01 00:00:00

abstract：:N6-methyladenosine (m6A) plays an important role in many cancers. However, few studies have examined the role of m6A in colorectal CRC. To examine the effect of m6A on CRC, we studied the genome of 591 CRC cases from The Cancer Genome Atlas (TCGA). The relationship between the messenger RNA (mRNA) expression, copy num...

journal_title：BioMed research international

authors： Zhang Q,Cai Y,Kurbatov V,Khan SA,Lu L,Zhang Y,Johnson CH

更新日期：2020-12-19 00:00:00

abstract：:Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE-/-) AS mice, which were trained by WBV (15 Hz, 30 m...

journal_title：BioMed research international

authors： Wu H,Zhang Y,Yang X,Li X,Shao Z,Zhou Z,Li Y,Pan S,Liu C

更新日期：2018-03-07 00:00:00

abstract：:Although the dynamic motions and peptidyl transferase activity seem to be embedded in the rRNAs, the ribosome contains more than 50 ribosomal proteins (r-proteins), whose functions remain largely elusive. Also, the precise forms of some of these r-proteins, as being part of the ribosome, are not structurally solved du...

journal_title：BioMed research international

authors： Chang KC,Wen JD,Yang LW

更新日期：2015-01-01 00:00:00

abstract：:Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-...

journal_title：BioMed research international

authors： Xu L,Sun Z,Fan Z

更新日期：2015-01-01 00:00:00

abstract：:Tumourigenesis is a mutation accumulation process, which is likely to start with a mutated founder cell. The evolutionary nature of tumor development makes phylogenetic models suitable for inferring tumor evolution through genetic variation data. Copy number variation (CNV) is the major genetic marker of the genome wi...

journal_title：BioMed research international

authors： Liang Y,Liao B,Zhu W

更新日期：2017-01-01 00:00:00

abstract：:In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...

journal_title：BioMed research international

authors： Rizzo L,Attanasio M,Pinzone MR,Berretta M,Malaguarnera M,Morra A,L'Abbate L,Balestreri L,Nunnari G,Cacopardo B

更新日期：2014-01-01 00:00:00

abstract：:For more than 30 years, heart transplantation has been a successful therapy for patients with terminal heart failure. Mechanical circulatory support (MCS) was developed as a therapy for end-stage heart failure at a time when cardiac transplantation was not yet a useful treatment modality. With the more successful outc...

journal_title：BioMed research international

authors： Anand J,Singh SK,Antoun DG,Cohn WE,Frazier OH,Mallidi HR

更新日期：2015-01-01 00:00:00

abstract：:Stimuli responsive pH- and temperature-sensitive hydrogel drug delivery systems, as those based on N-isopropylacrylamide (NiPAAm) and itaconic acid (IA), have been attracting much of the attention of the scientific community nowadays, especially in the field of drug release. By adjusting comonomer composition, the mat...

journal_title：BioMed research international

authors： Milašinović N,Knežević-Jugović Z,Milosavljević N,Lučić Škorić M,Filipović J,Kalagasidis Krušić M

更新日期：2014-01-01 00:00:00

abstract：:Vascular aging, a specific type of organic aging, is related to age-dependent changes in the vasculature, including atherosclerotic plaques, arterial stiffness, fibrosis, and increased intimal thickening. Vascular aging could influence the threshold, process, and severity of various cardiovascular diseases, thus makin...

journal_title：BioMed research international

authors： Lin X,Zhan JK,Wang YJ,Tan P,Chen YY,Deng HQ,Liu YS

更新日期：2016-01-01 00:00:00

abstract：Objectives:The study aimed to compare the accuracy of different methods of data acquisition and data reconstruction and to assess their usefulness for 3D printing of tooth replicas. Methods:3-dimensional models of molar and canine teeth obtain utilizing CBCT examination with different protocols, and optical scanning w...

journal_title：BioMed research international

authors： Kulczyk T,Rychlik M,Lorkiewicz-Muszyńska D,Abreu-Głowacka M,Czajka-Jakubowska A,Przystańska A

更新日期：2019-04-10 00:00:00

abstract：:Myocardial ischemia-reperfusion (I/R) injury is experienced by individuals suffering from cardiovascular diseases such as coronary heart diseases and subsequently undergoing reperfusion treatments in order to manage the conditions. The occlusion of blood flow to the tissue, termed ischemia, can be especially detriment...

journal_title：BioMed research international

authors： Zhou T,Chuang CC,Zuo L

更新日期：2015-01-01 00:00:00

abstract：:Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP...

journal_title：BioMed research international

authors： Luo G,Lu F,Qiao L,Chen X,Li G,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...

journal_title：BioMed research international

authors： Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A

更新日期：2015-01-01 00:00:00

abstract：:Protein structure prediction (PSP) is computationally a very challenging problem. The challenge largely comes from the fact that the energy function that needs to be minimised in order to obtain the native structure of a given protein is not clearly known. A high resolution 20 × 20 energy model could better capture th...

journal_title：BioMed research international

authors： Rashid MA,Newton MA,Hoque MT,Sattar A

更新日期：2013-01-01 00:00:00

abstract：:To investigate white matter (WM) abnormalities in neocortical epilepsy, we extract supratentorial WM parameters from raw tensor magnetic resonance images (MRI) with automated region-of-interest (ROI) registrations. Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched...

journal_title：BioMed research international

authors： Peng SJ,Harnod T,Tsai JZ,Huang CC,Ker MD,Chiou JC,Chiueh H,Wu CY,Hsin YL

更新日期：2014-01-01 00:00:00

abstract：:Increasing consumption of tobacco and alcohol has led to a steady increase in the incidence of head and neck cancers in Asia. The drawbacks associated with the existing chemotherapeutic and surgical interventions have necessitated the development of a safer alternative for therapy of head and neck cancers. In this stu...

journal_title：BioMed research international

authors： Mohan A,Narayanan S,Sethuraman S,Krishnan UM

更新日期：2014-01-01 00:00:00

abstract：:Background and Objective. Although minimally invasive surgical treatment of acute epidural hematoma attracts increasing attention, no generalized indications for the surgery have been adopted. This study aimed to evaluate the effects of minimally invasive surgery in acute epidural hematoma with various hematoma volume...

journal_title：BioMed research international

authors： Wang W

更新日期：2016-01-01 00:00:00

abstract：Objective:This study evaluated the bioactivity and physicochemical properties of three commercial calcium silicate-based endodontic materials (MTA, EndoSequence Root Repair Material putty, and Biodentine™). Material and Methods. Horizontal sections of 3 mm thickness from 18 root canals of human teeth were subjected to ...

journal_title：BioMed research international

authors： Talabani RM,Garib BT,Masaeli R

更新日期：2020-05-22 00:00:00

abstract：:The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis. This study, aimed to investigate whether exosomes originated from bone marrow-derived MSCs (BMSCs) preconditioned by deferoxamine (DFO-Exos)...

journal_title：BioMed research international

authors： Ding J,Wang X,Chen B,Zhang J,Xu J

更新日期：2019-05-05 00:00:00

abstract：:Growing evidence suggests that increased arginase activity affects vital bioprocesses in various systems and universally mediates the pathogenesis of numerous metabolic diseases. The adverse effects of arginase are associated with a severe decline in L-arginine bioavailability, which leads to nitric oxide synthase sub...

journal_title：BioMed research international

authors： Gilinsky MA,Polityko YK,Markel AL,Latysheva TV,Samson AO,Polis B,Naumenko SE

更新日期：2020-02-12 00:00:00