Effects of Cobalt Chloride, a Hypoxia-Mimetic Agent, on Autophagy and Atrophy in Skeletal C2C12 Myotubes.

abstract：:Ischemia/reperfusion (I/R) injury remains a major complication of liver resection, transplantation, and hemorrhagic shock. Although the mechanisms that contribute to hepatic I/R are complex and diverse involving the interaction of cell injury in hepatocytes, immune cells, and endothelium, mitochondrial dysfunction is ...

journal_title：BioMed research international

authors： Go KL,Lee S,Zendejas I,Behrns KE,Kim JS

更新日期：2015-01-01 00:00:00

abstract：:It is well known that Down syndrome (DS) is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Intellectual disability is the foremost and most debilitating trait, which caused loss of cognitive abilities and the development of early onset Alzheimer's d...

journal_title：BioMed research international

authors： Yu B,Zhang B,Zhou WB,Wang QW,Yuan P,Yang YQ,Kong J

更新日期：2015-01-01 00:00:00

abstract：:Aspergillus species originating from Greece were examined by morphological and molecular criteria to explore the diversity of this genus. The phylogenetic relationships of these species were determined using sequences from the ITS and IGS region of the nuclear rRNA gene complex, two nuclear genes ( β -tubulin (benA) a...

journal_title：BioMed research international

authors： Krimitzas A,Pyrri I,Kouvelis VN,Kapsanaki-Gotsi E,Typas MA

更新日期：2013-01-01 00:00:00

abstract：:Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamella...

journal_title：BioMed research international

authors： Liu Y,Ji M,Wong MK,Joo KI,Wang P

更新日期：2013-01-01 00:00:00

abstract：Result:In the denture wearers, HHV8 DNA was detected in 11 cases. Two of the controls amplified HHV8 DNA. Fisher's exact test demonstrates a significant difference between virus infection and using removable dentures (p = 0.015). Conclusion:Our findings suggested that HHV8 detection could be associated with use of den...

journal_title：BioMed research international

authors： Derafshi R,Ghapanchi J,Rezazadeh F,Kalantari MH,Naeeni AM,Farzin M,Moattari A

更新日期：2020-04-15 00:00:00

abstract：:Gender affirmation surgery remains one of the greatest challenges in transgender medicine. In recent years, there have been continuous discussions on bioethical aspects in the treatment of persons with gender dysphoria. Gender reassignment is a difficult process, including not only hormonal treatment with possible sur...

journal_title：BioMed research international

authors： Bizic MR,Jeftovic M,Pusica S,Stojanovic B,Duisin D,Vujovic S,Rakic V,Djordjevic ML

更新日期：2018-06-13 00:00:00

abstract：:The aim of the study was to comparatively evaluate the fracture strength and mode of root canal treated teeth restored with resin composites with and without posts. The lingual cusps of root canal treated first upper premolars (n = 10/group) were removed down to cervical enamel and restored with the following: group A...

journal_title：BioMed research international

authors： Gaintantzopoulou MD,Farmakis ET,Eliades GC

更新日期：2018-08-14 00:00:00

abstract：Aims:To investigate demographics and socioeconomic status in patients with ulnar nerve compression and the influence of socioeconomic factors on patient-reported outcome measurements (PROM) as evaluated by QuickDASH (short version of Disabilities of Arm, Shoulder and Hand) after surgery for ulnar nerve compression at t...

journal_title：BioMed research international

authors： Zimmerman M,Nyman E,Steen Carlsson K,Dahlin LB

更新日期：2020-12-18 00:00:00

abstract：:Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...

journal_title：BioMed research international

authors： Fernandes-Lima F,Gregório BM,Nascimento FAM,Costa WS,Gallo CBM,Sampaio FJB

更新日期：2018-04-23 00:00:00

abstract：:Craniofacial reconstruction is to estimate a person's face model from the skull. It can be applied in many fields such as forensic medicine, archaeology, and face animation. Craniofacial reconstruction is based on the relationship between the skull and the face to reconstruct the facial appearance from the skull. Howe...

journal_title：BioMed research international

authors： Wen Y,Mingquan Z,Pengyue L,Guohua G,Xiaoning L,Kang L

更新日期：2020-12-04 00:00:00

abstract：:Ischemia-reperfusion injury (IRI) is a major contributor to acute kidney injury (AKI). At present, there are no effective therapies to prevent AKI. The aim of this study was to analyse whether valproic acid (VPA), a histone deacetylase inhibitor with anti-inflammatory properties, prevents renal IRI. Male Wistar rats w...

journal_title：BioMed research international

authors： Costalonga EC,Silva FM,Noronha IL

更新日期：2016-01-01 00:00:00

abstract：:Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand-operated nonautomatable phloroglucinol reaction. This work demonstrates t...

journal_title：BioMed research international

authors： Sánchez-Moreno I,Monsalve-Hernando C,Godino A,Illa L,Gaspar MJ,Muñoz GM,Díaz A,Martín JL,García-Junceda E,Fernández-Mayoralas A,Hermida C

更新日期：2017-01-01 00:00:00

abstract：:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...

journal_title：BioMed research international

authors： Wang P,Wang J,Ma J,Jin G,Guan X

更新日期：2017-01-01 00:00:00

abstract：:[This retracts the article DOI: 10.1155/2015/108458.]. ...

journal_title：BioMed research international

authors： International BR

更新日期：2017-01-01 00:00:00

abstract：:This study investigated how the posture of the thumb while performing common pinch movements and the levels of pinch force applied by the thumb affect the arthrokinematics of the trapeziometacarpal joint in vivo. Fifteen subjects performed the pinch tasks at the distal phalange (DP), proximal interphalangeal (PIP) joi...

journal_title：BioMed research international

authors： Kuo LC,Lin CJ,Chen GP,Jou IM,Wang CK,Goryacheva IG,Dosaev MZ,Su FC

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Radiopharmaceutical production process must adhere to current good manufacturing process (CGMP) compliance to ensure the quality of precursor, prodrug (active pharmaceutical ingredient, API), and the final drug product that meet acceptance criteria. We aimed to develop an automated system for production of CG...

journal_title：BioMed research international

authors： Chi YT,Chu PC,Chao HY,Shieh WC,Chen CC

更新日期：2014-01-01 00:00:00

abstract：:Regulation of hematopoietic stem cell release, migration, and homing from the bone marrow (BM) and of the mobilization pathway involves a complex interaction among adhesion molecules, cytokines, proteolytic enzymes, stromal cells, and hematopoietic cells. The identification of new mechanisms that regulate the traffick...

journal_title：BioMed research international

authors： Alvarez P,Carrillo E,Vélez C,Hita-Contreras F,Martínez-Amat A,Rodríguez-Serrano F,Boulaiz H,Ortiz R,Melguizo C,Prados J,Aránega A

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To compare the quantity, subtype, and progression of atherosclerosis by cardiac computed tomography (CT) and intravascular ultrasound (IVUS) in patients with stable (SAP) and unstable angina pectoris or non-ST-elevation myocardial infarction (UAP/n-STEMI). METHODS:Forty patients with SAP and 20 with UAP/n-ST...

journal_title：BioMed research international

authors： Dalager MG,Bøttcher M,Thygesen J,Andersen G,Bøtker HE

更新日期：2015-01-01 00:00:00

abstract：Background:This study investigated the potential therapeutic effects of acupoint catgut embedding (ACE) at ST36 and BL13 on lipopolysaccharide- (LPS-) induced acute respiratory distress syndrome (ARDS) in rats. Materials and Methods:Male Sprague-Dawley rats were randomized into the normal saline (NS group with a sham ...

journal_title：BioMed research international

authors： Li D,Sun T,Chi L,Zhao D,Li W

更新日期：2020-05-02 00:00:00

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：:Pterygium is a relatively common eye disease that can display an aggressive clinical behaviour. To evaluate the in vitro effects of Curcuma longa on human pterygium-derived keratinocytes, specimens of pterygium from 20 patients undergoing pterygium surgical excision were collected. Pterygium explants were put into cul...

journal_title：BioMed research international

authors： Sancilio S,Di Staso S,Sebastiani S,Centurione L,Di Girolamo N,Ciancaglini M,Di Pietro R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

journal_title：BioMed research international

authors： Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

更新日期：2016-01-01 00:00:00

abstract：Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

journal_title：BioMed research international

authors： Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

更新日期：2019-12-14 00:00:00

abstract：:Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

journal_title：BioMed research international

authors： Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

更新日期：2020-01-23 00:00:00

abstract：UNLABELLED:The safety and efficacy of endoscopic sphincterotomy with large balloon dilation (EPLBD) are unclear. This study compares the safety and efficacy between EPLBD and endoscopic sphincterotomy (EST). PATIENTS AND METHODS:Literatures were searched for randomized controlled trials in PUBMED, EMBASE, and Cochrane...

journal_title：BioMed research international

authors： Xu L,Kyaw MH,Tse YK,Lau JY

更新日期：2015-01-01 00:00:00

abstract：:Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...

journal_title：BioMed research international

authors： Matar KM

更新日期：2013-01-01 00:00:00

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：:Seed inoculation with bacterial consortium was found to increase legume yield, providing a higher growth than the standard nitrogen treatment methods. Alfalfa plants were inoculated by mono- and binary compositions of nitrogen-fixing microorganisms. Their physiological and biochemical properties were estimated. Inocul...

journal_title：BioMed research international

authors： Karaushu EV,Lazebnaya IV,Kravzova TR,Vorobey NA,Lazebny OE,Kiriziy DA,Olkhovich OP,Taran NY,Kots SY,Popova AA,Omarova E,Koksharova OA

更新日期：2015-01-01 00:00:00

abstract：Objective:The current study aimed to investigate the effects of body position on the level and severity of stuttering in young adults with developmental stuttering. Methods:A total of 24 subjects (male: 17; female: 7; mean age: 24.9 ± 6.2 years) with developmental stuttering participated. The participants were asked t...

journal_title：BioMed research international

authors： Almudhi A,Zafar H,Anwer S,Alghadir A

更新日期：2019-08-05 00:00:00

abstract：:The discovery of evolutionarily conserved Atg genes required for autophagy in yeast truly revolutionized this research field and made it possible to carry out functional studies on model organisms. Insects including Drosophila are classical and still popular models to study autophagy, starting from the 1960s. This rev...

journal_title：BioMed research international

authors： Mulakkal NC,Nagy P,Takats S,Tusco R,Juhász G,Nezis IP

更新日期：2014-01-01 00:00:00