Abstract:
UNLABELLED:The safety and efficacy of endoscopic sphincterotomy with large balloon dilation (EPLBD) are unclear. This study compares the safety and efficacy between EPLBD and endoscopic sphincterotomy (EST). PATIENTS AND METHODS:Literatures were searched for randomized controlled trials in PUBMED, EMBASE, and Cochrane Library. Outcome measurements included adverse events; stone removal rate; requirement of mechanical lithotripsy. RESULTS:Four RCTs with a total of 596 patients were included. Three RCTs compared EPLBD versus EST alone for stone removal; one RCT compared EPLBD versus EST plus mechanical lithotripsy for stone removal. Pooled data from three RCTs showed that there was no significant difference in the adverse event of ERCP. A significantly higher cholangitis rate was seen in patients who received EST plus mechanical lithotripsy, compared to those treated with EPLBD (13.3% versus 0.0, P = 0.026). No statistical difference was found between EPLBD and EST for stone removal rate. Significant differences in requirement of mechanical lithotripsy were seen with removal of large stones (>15 mm), with EPLBD reducing the use of mechanical lithotripsy (RR: 0.73; 95% CI: 0.54-0.99). CONCLUSIONS:EPLBD and EST have similar efficacy and safety for bile duct stones clearance. With larger stones, EPLBD can reduce requirement of mechanical lithotripsy.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Xu L,Kyaw MH,Tse YK,Lau JYdoi
10.1155/2015/673103subject
Has Abstractpub_date
2015-01-01 00:00:00pages
673103eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
杂志文章,meta分析,评审abstract::Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/9017902
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/519830
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
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doi:10.1155/2018/4934861
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/769867
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/342529
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/7463590
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/387673
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/6289380
更新日期:2019-05-29 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/636847
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1155/2014/842452
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2017/6925079
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2020-12-22 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/167196
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/919374
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2014/102164
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/2182735
更新日期:2020-10-28 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/102479
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2013/424280
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/108902
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/818656
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/481019
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abstract::In vitro research performed on eukaryotic or prokaryotic cell cultures usually represents the initial step for characterization of a novel photosensitizer (PS) intended for application in photodynamic therapy (PDT) of cancer or photodynamic inactivation (PDI) of microorganisms. Although many experimental steps of PS t...
journal_title:BioMed research international
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2719460
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/802945
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/4616417
更新日期:2019-08-25 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9240581
更新日期:2020-01-22 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/841615
更新日期:2014-01-01 00:00:00