Antiosteoclastic activity of milk thistle extract after ovariectomy to suppress estrogen deficiency-induced osteoporosis.

abstract：OBJECTIVE:To determine the histopathological differences after varicocele repair in testicular tissue in males with nonobstructive azoospermia. METHODS:Between 2009 and 2014, 45 men with complete azoospermia and palpable varicocele, presenting with primary infertility of at least 1 year, undergoing varicocele repair a...

journal_title：BioMed research international

authors： Ustuner M,Yilmaz H,Yavuz U,Ciftci S,Saribacak A,Aynur BS,Yasar H,Culha MM

更新日期：2015-01-01 00:00:00

abstract：:Presynaptic and postsynaptic neurotoxins are proteins which act at the presynaptic and postsynaptic membrane. Correctly predicting presynaptic and postsynaptic neurotoxins will provide important clues for drug-target discovery and drug design. In this study, we developed a theoretical method to discriminate presynapti...

journal_title：BioMed research international

authors： Tang H,Yang Y,Zhang C,Chen R,Huang P,Duan C,Zou P

更新日期：2017-01-01 00:00:00

abstract：:Lipids have been widely used as main constituents in various drug delivery systems, such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, and lipid-based lyotropic liquid crystals. Among them, lipid-based lyotropic liquid crystals have highly ordered, thermodynamically stable internal nanostruct...

journal_title：BioMed research international

authors： Chen Y,Ma P,Gui S

更新日期：2014-01-01 00:00:00

abstract：:Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

journal_title：BioMed research international

authors： Cui Y,Cai M,Stanley HE

更新日期：2017-01-01 00:00:00

abstract：:In vitro research performed on eukaryotic or prokaryotic cell cultures usually represents the initial step for characterization of a novel photosensitizer (PS) intended for application in photodynamic therapy (PDT) of cancer or photodynamic inactivation (PDI) of microorganisms. Although many experimental steps of PS t...

journal_title：BioMed research international

authors： Kiesslich T,Gollmer A,Maisch T,Berneburg M,Plaetzer K

更新日期：2013-01-01 00:00:00

abstract：:Autoimmunity remains a complex physiologic deviation, enabled and perpetuated by a variety of interplayers and pathways. Simplistic approaches, targeting either isolated end-effectors of more centrally placed interactors of these mechanisms, are continuously tried in an effort to comprehend and halt cascades with pote...

journal_title：BioMed research international

authors： Pateinakis P,Pyrpasopoulou A

更新日期：2014-01-01 00:00:00

abstract：:We aimed to assess the prevalence of hospitalization for endometriosis in the general population in France and in each French region and to describe temporal trends, rehospitalization rates, and prevalence of the different types of endometriosis. The analyses were carried out on French hospital discharge data and cove...

journal_title：BioMed research international

authors： von Theobald P,Cottenet J,Iacobelli S,Quantin C

更新日期：2016-01-01 00:00:00

abstract：:5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...

journal_title：BioMed research international

authors： Zhu Y,Xu L,Fan Y,Li C,Zhang Y,Zheng H,Hou K,Qu X,Liu Y

更新日期：2013-01-01 00:00:00

abstract：:Natural enzyme mimics have attracted considerable attention due to leakage of enzymes and their easy denaturation during their storage and immobilization procedure. Here in this study, for the first time, a new iron oxide hydroxide, ferrihydrite - Fe1.44O0.32 (OH) 3.68 magnetic nanoparticles were synthesized by bacter...

journal_title：BioMed research international

authors： Ahmed A,Abagana A,Cui D,Zhao M

更新日期：2019-03-28 00:00:00

abstract：:Objectives. Lung ultrasonography (LUS) is a useful examination to identify lung problems. Unfortunately, there are currently no LUS educational programs for medical students. We designed a brief LUS training course for medical students during the ED rotation. The purpose of training was improving cognitive and psychom...

journal_title：BioMed research international

authors： Lim JS,Lee S,Do HH,Oh KH

更新日期：2017-01-01 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：:The uncertain position of lung tumor during radiotherapy compromises the treatment effect. To effectively control respiratory motion during radiotherapy of lung cancer without any side effects, a novel control scheme, hypnosis, has been introduced in lung cancer treatment. In order to verify the suggested method, six ...

journal_title：BioMed research international

authors： Li R,Deng J,Xie Y

更新日期：2013-01-01 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：Objective:The aim of this study is to evaluate the efficacy and safety of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF). Methods. Embase, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature ...

journal_title：BioMed research international

authors： Yu X,Li X,Wang L,Liu R,Xie Y,Li S,Li J

更新日期：2019-03-21 00:00:00

abstract：:Probiotic Lactobacillus casei Shirota (LcS) is a potential decontaminating agent of aflatoxin B1 (AFB1). However, few studies have investigated the influence of diet, especially a high protein (HP) diet, on the binding of AFB1 by probiotics. This research was conducted to determine the effect of HP diet on the ability...

journal_title：BioMed research international

authors： Nurul Adilah Z,Liew WP,Mohd Redzwan S,Amin I

更新日期：2018-05-23 00:00:00

abstract：Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...

journal_title：BioMed research international

authors： Zhao Y,Song YQ,Gao J,Feng SY,Li Y

更新日期：2019-07-15 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：Objective:This study aimed to investigate the effects of Ang-1 on neovascularization of diabetic organs by subcutaneous Matrigel angiogenesis model, established in type 1 diabetic rats. Methods:Ang-1 adenoviral vector was constructed. The rat model was established by STZ and divided into four group. The Matrigel was i...

journal_title：BioMed research international

authors： Li S,Zou H,Gong M,Chen Y,Yan X,Yu L,Yang Y

更新日期：2019-01-09 00:00:00

abstract：Objectives:The study aimed to compare the accuracy of different methods of data acquisition and data reconstruction and to assess their usefulness for 3D printing of tooth replicas. Methods:3-dimensional models of molar and canine teeth obtain utilizing CBCT examination with different protocols, and optical scanning w...

journal_title：BioMed research international

authors： Kulczyk T,Rychlik M,Lorkiewicz-Muszyńska D,Abreu-Głowacka M,Czajka-Jakubowska A,Przystańska A

更新日期：2019-04-10 00:00:00

abstract：:Morphine is considered a highly potent analgesic agent used to relieve suffering of patients with cancer. Several in vitro and in vivo studies showed that morphine also modulates angiogenesis and regulates tumour cell growth. Unfortunately, the results obtained by these studies are still contradictory. In order to bet...

journal_title：BioMed research international

authors： Bimonte S,Barbieri A,Rea D,Palma G,Luciano A,Cuomo A,Arra C,Izzo F

更新日期：2015-01-01 00:00:00

abstract：:Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...

journal_title：BioMed research international

authors： Chen WP,Chang SH,Tang CY,Liou ML,Tsai SJ,Lin YL

更新日期：2018-11-15 00:00:00

abstract：:As emerging tick born rickettsial diseases caused by A. phagocytophilum and E. chaffeensis, anaplasmosis and ehrlichiosis have become a serious threat to human and animal health throughout the world. In particular, in China, an unusual transmission of nosocomial cases of human granulocytic anaplasmosis occurred in Anh...

journal_title：BioMed research international

authors： Zhang L,Liu H,Xu B,Zhang Z,Jin Y,Li W,Lu Q,Li L,Chang L,Zhang X,Fan D,Cao M,Bao M,Zhang Y,Guan Z,Cheng X,Tian L,Wang S,Yu H,Yu Q,Wang Y,Zhang Y,Tang X,Yin J,Lao S,Wu B,Li J,Li W,Xu Q,Shi Y,Huan

更新日期：2014-01-01 00:00:00

abstract：:Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

journal_title：BioMed research international

authors： Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

更新日期：2020-08-26 00:00:00

abstract：:Myocardial ischemia-reperfusion (I/R) injury is experienced by individuals suffering from cardiovascular diseases such as coronary heart diseases and subsequently undergoing reperfusion treatments in order to manage the conditions. The occlusion of blood flow to the tissue, termed ischemia, can be especially detriment...

journal_title：BioMed research international

authors： Zhou T,Chuang CC,Zuo L

更新日期：2015-01-01 00:00:00

abstract：Background:Salinity is one of the major abiotic constraints that hinder health and quality of crops. Conversely, halotolerant plant growth-promoting rhizospheric (PGPR) bacteria are considered biologically safe for alleviating salinity stress. Results:We isolated halotolerant PGPR strains from the rhizospheric soil of...

journal_title：BioMed research international

authors： Khan MA,Asaf S,Khan AL,Adhikari A,Jan R,Ali S,Imran M,Kim KM,Lee IJ

更新日期：2019-10-20 00:00:00

abstract：:Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO ofte...

journal_title：BioMed research international

authors： Kida T

更新日期：2017-01-01 00:00:00

abstract：Background:Acute myocardial infarction (AMI) is regarded as an urgent clinical entity, and identification of differentially expressed genes, lncRNAs, and altered pathways shall provide new insight into the molecular mechanisms behind AMI. Materials and Methods:Microarray data was collected to identify key genes and ln...

journal_title：BioMed research international

authors： Sheng X,Fan T,Jin X

更新日期：2020-10-06 00:00:00

abstract：:Metabolic bone disorder is usually caused by abnormalities of minerals and hormones metabolism. Recently, it has been proved by several studies that the renin-angiotensin system (RAS) in local bone tissue is directly involved in bone metabolism. Activation of skeletal RAS plays an important role in bone metabolic diso...

journal_title：BioMed research international

authors： Gebru Y,Diao TY,Pan H,Mukwaya E,Zhang Y

更新日期：2013-01-01 00:00:00

abstract：:The impact of a premature elevation of serum progesterone level, the day of hCG administration in patients under controlled ovarian stimulation during IVF procedure, on human endometrial receptivity is still debated. In the present study, we investigated the endometrial gene expression profile shifts during the prerec...

journal_title：BioMed research international

authors： Haouzi D,Bissonnette L,Gala A,Assou S,Entezami F,Perrochia H,Dechaud H,Hugues JN,Hamamah S

更新日期：2014-01-01 00:00:00

abstract：Background:Currently, effective genetic markers are limited to predict the clinical outcome of melanoma. High-throughput multiomics sequencing data have provided a valuable approach for the identification of genes associated with cancer prognosis. Method:The multidimensional data of melanoma patients, including clinic...

journal_title：BioMed research international

authors： Gao Y,Li Y,Niu X,Wu Y,Guan X,Hong Y,Chen H,Song B

更新日期：2020-05-08 00:00:00