Abstract:
:Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 and 36 weeks of gestation, with premature labor, who finally had preterm birth. Group B contained 66 women in labor between 37 and 41 weeks of gestation. Women in group A had lower SDF-1α and sRAGE levels than those in group B. Moreover, in group A, SDF-1α and sRAGE levels were correlated with the latency period from the occurrence of premature labor symptoms until delivery. Sensitivity and specificity of studied parameters for prediction of preterm birth were 95% and 40% for SDF-1α and 51.3% and 93.5% for sRAGE, respectively. The prognostic value of plasma SDF-1α and sRAGE levels was comparable with that of cervical length ultrasound measurement and serum C-reactive protein levels. We conclude that SDF-1α and sRAGE appear to play a major role in the diagnosis of preterm birth and its evaluation could be convenient and useful for predicting preterm birth.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé Adoi
10.1155/2016/2719460subject
Has Abstractpub_date
2016-01-01 00:00:00pages
2719460eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章abstract::[This corrects the article DOI: 10.1155/2015/587135.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
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