Overexpression of D-xylose reductase (xyl1) gene and antisense inhibition of D-xylulokinase (xyiH) gene increase xylitol production in Trichoderma reesei.

abstract：:One of the biggest obstetric challenges is the diagnosis and management of a short cervix as cervical length has an inverse relationship with risk of preterm birth. A cervical cerclage is a surgical procedure to reduce the risk of preterm birth and can be placed in an elective or emergency setting. This is a retrospec...

journal_title：BioMed research international

authors： Vasudeva N,Reddington C,Bogdanska M,De Luca L

更新日期：2018-09-30 00:00:00

abstract：:Leishmaniasis is a complex of diseases caused by protozoa of the genus Leishmania and affects millions of people around the world. Several species of plants are used by traditional communities for the treatment of this disease, among which is Carapa guianensis Aubl. (Meliaceae), popularly known as andiroba. The object...

journal_title：BioMed research international

authors： Oliveira IDSDS,Moragas Tellis CJ,Chagas MDSDS,Behrens MD,Calabrese KDS,Abreu-Silva AL,Almeida-Souza F

更新日期：2018-09-06 00:00:00

abstract：:Several studies suggested that migraine attack onset shows a circadian variation; however, there has not been an overview and synthesis of these findings. A PubMed search with keywords "migraine" AND "circadian" resulted in ten studies directly investigating this topic. Results of these studies mostly show that migrai...

journal_title：BioMed research international

authors： Baksa D,Gecse K,Kumar S,Toth Z,Gal Z,Gonda X,Juhasz G

更新日期：2019-08-25 00:00:00

abstract：:One of the most common complications of diabetes mellitus is diabetic neuropathy. It may be provoked by metabolic and/or vascular factors, and depending on duration of disease, various layers of nerve may be affected. Our aim was to investigate influence of diabetes on the epineurial, perineurial, and endoneurial conn...

journal_title：BioMed research international

authors： Kundalić B,Ugrenović S,Jovanović I,Stefanović N,Petrović V,Kundalić J,Stojanović V,Živković V,Antić V

更新日期：2014-01-01 00:00:00

abstract：:Solid lipid nanoparticle is an efficient lipid based drug delivery system which can enhance the bioavailability of poorly water soluble drugs. Efavirenz is a highly lipophilic drug from nonnucleoside inhibitor category for treatment of HIV. Present work illustrates development of an SLN formulation for Efavirenz with ...

journal_title：BioMed research international

authors： Gaur PK,Mishra S,Bajpai M,Mishra A

更新日期：2014-01-01 00:00:00

abstract：:To evaluate the role of Cystatin C (Cys-C) in tumorigenesis and progression of prostate cancer (PCa), we retrospectively collected the clinical information from the records of 492 benign prostatic hyperplasia (BPH), 48 prostatic intraepithelial neoplasia (PIN), and 173 PCa patients, whose disease was newly diagnosed a...

journal_title：BioMed research international

authors： Yang F,Li D,Di Y,Zhang Y,Zang Y,Ren J,Yan L,Zhou Z,Liu H,Xu Z

更新日期：2017-01-01 00:00:00

abstract：:Microalgae are a promising source of omega-3. The purpose of this study was to extract lipid with a relatively high content of eicosapentaenoic acid (EPA) from Nannochloropsis gaditana using subcritical water extraction (SWE). The effects of different temperatures (156.1-273.9°C), extraction times (6.6-23.4 minutes), ...

journal_title：BioMed research international

authors： Ho BCH,Kamal SMM,Danquah MK,Harun R

更新日期：2018-12-27 00:00:00

abstract：:Vitamin D deficiency is associated with a number of human disorders, including cardiovascular disease, cancer, diabetes, frailty, and infections. Since an association between vitamin D and migraine has also been recently speculated, we performed an electronic search on Medline, Scopus, and Web of Science using the key...

journal_title：BioMed research international

authors： Lippi G,Cervellin G,Mattiuzzi C

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/8193821.]. ...

journal_title：BioMed research international

authors： Kawano S,Takaki A,Iwamuro M,Yasunaka T,Kono Y,Miura K,Inokuchi T,Kawahara Y,Umeda Y,Yagi T,Okada H

更新日期：2017-01-01 00:00:00

abstract：:The impact of a premature elevation of serum progesterone level, the day of hCG administration in patients under controlled ovarian stimulation during IVF procedure, on human endometrial receptivity is still debated. In the present study, we investigated the endometrial gene expression profile shifts during the prerec...

journal_title：BioMed research international

authors： Haouzi D,Bissonnette L,Gala A,Assou S,Entezami F,Perrochia H,Dechaud H,Hugues JN,Hamamah S

更新日期：2014-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts. In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial re...

journal_title：BioMed research international

authors： Pradenas GA,Díaz-Vásquez WA,Pérez-Donoso JM,Vásquez CC

更新日期：2013-01-01 00:00:00

abstract：:In the biomedical field, there is growing interest in using human stem cell-derived neurons as in vitro models for pharmacological and toxicological screening of bioactive compounds extracted from natural products. Lignosus rhinocerus (Tiger Milk Mushroom) is used by indigenous communities in Malaysia as a traditional...

journal_title：BioMed research international

authors： Yeo Y,Tan JBL,Lim LW,Tan KO,Heng BC,Lim WL

更新日期：2019-08-19 00:00:00

abstract：OBJECTIVE:There is a paucity of a biological large animal model of myocardial infarction (MI). We hypothesized that, using autologous-aggregated platelets, we could create an ovine model that was reproducible and more closely mimicked the pathophysiology of MI. METHODS:Mepacrine stained autologous platelets from male ...

journal_title：BioMed research international

authors： Spata T,Bobek D,Whitson BA,Parthasarathy S,Mohler PJ,Higgins RS,Kilic A

更新日期：2013-01-01 00:00:00

abstract：:The present study showed that oral mushroom beta-glucan treatment significantly increased IFN-γ mRNA expression but significantly reduced COX-2 mRNA expression within the lung. For LLC tumor model, oral Ganoderma lucidum or Antrodia camphorata polysaccharides treatments significantly reduced TGF-β production in serum....

journal_title：BioMed research international

authors： Wang WJ,Wu YS,Chen S,Liu CF,Chen SN

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of transcatheter arterial chemoembolization (TACE) using warmed and nonwarmed miriplatin for hepatocellular carcinoma. Eighty patients (117 nodules), treated between January 2010 and June 2013, were evaluated. Thirty-two and 85 nodules were treated with non...

journal_title：BioMed research international

authors： Yasui D,Murata S,Onozawa S,Mine T,Ueda T,Sugihara F,Kawamoto C,Uchida E,Kumita S

更新日期：2014-01-01 00:00:00

abstract：:Small intestinal bacterial overgrowth (SIBO) is associated with chronic gastrointestinal diseases and structural/functional abnormalities of the gastrointestinal tract. SIBO's association with clinical characteristics is unclear. This study investigates the association between clinical factors and SIBO according to la...

journal_title：BioMed research international

authors： Newberry C,Tierney A,Pickett-Blakely O

更新日期：2016-01-01 00:00:00

abstract：Background:Recurrent shoulder dislocations occur much more frequently in adolescents than in the older population but a clear explanation of this incidence does not exist. The aim of the present study was to define the age-related distribution of the elastic fibers (EFs) in the shoulder capsule's extracellular matrix a...

journal_title：BioMed research international

authors： Castagna A,Cesari E,Gigante A,Di Matteo B,Garofalo R,Porcellini G

更新日期：2018-07-18 00:00:00

abstract：:MicroRNAs (miRNAs) family, which is involved in cancer development, proliferation, apoptosis, and drug resistance, is a group of noncoding RNAs that modulate the expression of oncogenes and antioncogenes. Doxorubicin is an active cytotoxic agent for breast cancer treatment, but the acquisition of doxorubicin resistanc...

journal_title：BioMed research international

authors： Long J,Ji Z,Jiang K,Wang Z,Meng G

更新日期：2015-01-01 00:00:00

abstract：:Feed efficiency (FE) is an important trait affecting costs in swine industry. Investigation on FE-related genes in different tissues is valuable for molecular breeding. Hypothalamus is a convergent and integrated centre for multiple nutrient-related signals. The present study identified 363 differentially expressed (D...

journal_title：BioMed research international

authors： Hou Y,Hu M,Zhou H,Li C,Li X,Liu X,Zhao Y,Zhao S

更新日期：2018-12-26 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is one of the most common cancers in the world. Our aim is to identify prognostic biomarkers that contribute to the progression of early stage ccRCC and clarify the mechanism. Here, the mRNA microarray expression profile of ccRCC samples was obtained from Gene Expression Omnibus...

journal_title：BioMed research international

authors： Qiu X,Gu Y,Ni Y,Li Q

更新日期：2020-10-29 00:00:00

abstract：:Maintenance of proper oral hygiene by dental plaque elimination is one of the most important factors affecting the healing process in postoperative oral wounds. Propolis is a substance produced by bees. Ethanolic extract of propolis has bactericidal, fungicidal, anti-inflammatory, and antioxidative properties. Moreove...

journal_title：BioMed research international

authors： Niedzielska I,Puszczewicz Z,Mertas A,Niedzielski D,Różanowski B,Baron S,Konopka T,Machorowska-Pieniążek A,Skucha-Nowak M,Tanasiewicz M,Paluch J,Markowski J,Orzechowska-Wylęgała B,Król W,Morawiec T

更新日期：2016-01-01 00:00:00

abstract：:POZ/BTB domains are widespread modules detected in a variety of different biological contexts. Here, we report a biophysical characterization of the POZ/BTB of KCTD6, a protein that is involved in the turnover of the muscle small ankyrin-1 isoform 5 and, in combination with KCTD11, in the ubiquitination and degradatio...

journal_title：BioMed research international

authors： Pirone L,Esposito C,Correale S,Graziano G,Di Gaetano S,Vitagliano L,Pedone E

更新日期：2013-01-01 00:00:00

abstract：Background:Thyroid cancer is the most common endocrine malignancy, with a recent global increase of 20% in age-related incidence. Ultrasonography and ultrasonography-guided fine-needle aspiration biopsy (FNAB) are the most widely used diagnostic tests for thyroid nodules; however, it is estimated that up to 25% of thyr...

journal_title：BioMed research international

authors： Nan BY,Xiong GF,Zhao ZR,Gu X,Huang XS

更新日期：2021-01-12 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:As emerging tick born rickettsial diseases caused by A. phagocytophilum and E. chaffeensis, anaplasmosis and ehrlichiosis have become a serious threat to human and animal health throughout the world. In particular, in China, an unusual transmission of nosocomial cases of human granulocytic anaplasmosis occurred in Anh...

journal_title：BioMed research international

authors： Zhang L,Liu H,Xu B,Zhang Z,Jin Y,Li W,Lu Q,Li L,Chang L,Zhang X,Fan D,Cao M,Bao M,Zhang Y,Guan Z,Cheng X,Tian L,Wang S,Yu H,Yu Q,Wang Y,Zhang Y,Tang X,Yin J,Lao S,Wu B,Li J,Li W,Xu Q,Shi Y,Huan

更新日期：2014-01-01 00:00:00

abstract：:Beta-1,3-glucanosyltransferase (Gas1p) plays important roles in cell wall biosynthesis and morphogenesis and has been implicated in DNA damage responses and cell cycle regulation in fungi. Yeast Gas1p has also been reported to participate in endoplasmic reticulum (ER) stress responses. However, the precise roles and m...

journal_title：BioMed research international

authors： Cui HJ,Cui XG,Jing X,Yuan Y,Chen YQ,Sun YX,Zhao W,Liu XG

更新日期：2019-06-02 00:00:00

abstract：Purpose:To study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats. Methods:A high-fat diet (HF) was given to 28 rats and 28 ...

journal_title：BioMed research international

authors： Stygar D,Pigłowski W,Chełmecka E,Skrzep-Poloczek B,Sawczyn T,Garłowski W,Jochem J,Karcz KW

更新日期：2018-08-16 00:00:00

abstract：:Heart failure is a major and costly problem in public health, which, in certain cases, may lead to death. The failing heart undergo a series of electrical and structural changes that provide the underlying basis for disturbances like arrhythmias. Computer models of coupled electrical and mechanical activities of the h...

journal_title：BioMed research international

authors： Rocha BM,Toledo EM,Barra LP,dos Santos RW

更新日期：2015-01-01 00:00:00

abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

journal_title：BioMed research international

authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

更新日期：2014-01-01 00:00:00

abstract：:Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...

journal_title：BioMed research international

authors： Adamska E,Ostrowska L,Gościk J,Waszczeniuk M,Krętowski A,Górska M

更新日期：2015-01-01 00:00:00