Oxidative Stress Induced by Polymyxin E Is Involved in Rapid Killing of Paenibacillus polymyxa.

Abstract:

:Historically, the colistin has been thought to kill bacteria through membrane lysis. Here, we present an alternative mechanism that colistin induces rapid Paenibacillus polymyxa death through reactive oxygen species production. This significantly augments our understanding of the mechanism of colistin action, which is critical knowledge toward the yield development of colistin in the future.

journal_name

Biomed Res Int

authors

Yu Z,Zhu Y,Qin W,Yin J,Qiu J

doi

10.1155/2017/5437139

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

5437139

eissn

2314-6133

issn

2314-6141

journal_volume

2017

pub_type

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