Abstract:
Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults with degenerative meniscal tears without symptoms of locking were considered for inclusion. Two researchers independently performed the literature search, assessed the risk of bias, and selected eligible studies. The primary outcome was function at different follow-up time points and the secondary outcome was pain at different follow-up time points. Results:We included 6 randomized controlled trials, with a total of 1006 participants, among which 495 were in the APM group and 511 were in the PT group. We found a small benefit in functional outcomes in the APM group until the 12 months follow-up time point (SMD = 0.20; 95%CI = 0.0-0.33; p = 0.002; I2 = 34%), but no significant differences in function between groups at the 24-month follow-up time point (SMD = 0.12; 95%CI = -0.04 - 0.28; p = 0.002; I2 = 34%), but no significant differences in function between groups at the 24-month follow-up time point (SMD = 0.12; 95%CI = -0.04 - 0.28; p = 0.002; I2 = 34%), but no significant differences in function between groups at the 24-month follow-up time point (SMD = 0.12; 95%CI = -0.04 - 0.28; p = 0.002; I2 = 34%), but no significant differences in function between groups at the 24-month follow-up time point (SMD = 0.12; 95%CI = -0.04 - 0.28. Conclusion:In the treatment of degenerative meniscus tears, APM yielded better functional and pain outcomes compared with physical therapy in the short term until 12 months, but there were comparable results for pain and functional outcomes between the groups at the 24 months follow-up time point.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Li J,Zhu W,Gao X,Li Xdoi
10.1155/2020/1709415subject
Has Abstractpub_date
2020-03-03 00:00:00pages
1709415eissn
2314-6133issn
2314-6141journal_volume
2020pub_type
杂志文章,meta分析abstract:OBJECTIVE:Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/820654
更新日期:2015-01-01 00:00:00
abstract::Besides the pinpointing of individual disease-related genes, associating protein complexes to human inherited diseases is also of great importance, because a biological function usually arises from the cooperative behaviour of multiple proteins in a protein complex. Moreover, knowledge about disease-related protein co...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/732650
更新日期:2013-01-01 00:00:00
abstract::MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes. Their deregulation is thus often causative of human malignancies, including cancers. Numerous studies have implicated microRNAs in the different steps of tumorigenesis including initiation, progression, metastasis, and ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/642916
更新日期:2014-01-01 00:00:00
abstract::A number of statistical methods for detecting gene-gene interactions have been developed in genetic association studies with binary traits. However, many phenotype measures are intrinsically quantitative and categorizing continuous traits may not always be straightforward and meaningful. Association of gene-gene inter...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/523641
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Most developmental processes are under the control of small regulatory RNAs called microRNAs (miRNAs). We hypothesize that different fetal developmental processes might be reflected by extracellular miRNAs in maternal plasma and may be utilized as biomarkers for the noninvasive prenatal diagnosis of chromoso...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/402475
更新日期:2014-01-01 00:00:00
abstract::This study investigated the role of gender as a potential predictor of health behaviour and potential moderator of the relationship between emotional intelligence and health behaviour. This cross-sectional study included 1214 students (597 males and 617 females). Data were collected using the Schutte Self-Report Inven...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7058105
更新日期:2018-06-04 00:00:00
abstract::[This corrects the article DOI: 10.1155/2018/2109865.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2019/6212386
更新日期:2019-12-13 00:00:00
abstract::The knowledge on the genetic etiology of complex disorders largely results from the study of rare monogenic disorders. Often these common and rare diseases show phenotypic overlap, though monogenic diseases generally have a more extreme symptomatology. ABCC6, the gene responsible for pseudoxanthoma elasticum, an autos...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/648569
更新日期:2015-01-01 00:00:00
abstract::This study was designed to explore the effect of basic fibroblast growth factor (bFGF) on radiation-induced endothelial dysfunction and histological changes in the urinary bladder. bFGF was administrated to human umbilical vein cells (HUVEC) or urinary bladder immediately after radiation. Reduced expression of thrombo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/967680
更新日期:2015-01-01 00:00:00
abstract::Primary ciliary dyskinesia (PCD) is a clinical rare peculiar disorder, mainly featured by respiratory infection, tympanitis, nasosinusitis, and male infertility. Previous study demonstrated it is an autosomal recessive disease and by 2017 almost 40 pathologic genes have been identified. Among them are the leucine-rich...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1854269
更新日期:2018-01-08 00:00:00
abstract::This paper describes a pilot study using a prototype telerehabilitation system (Ghostman). Ghostman is a visual augmentation system designed to allow a physical therapist and patient to inhabit each other's viewpoint in an augmented real-world environment. This allows the therapist to deliver instruction remotely and ...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/646347
更新日期:2014-01-01 00:00:00
abstract::Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4350783
更新日期:2020-04-15 00:00:00
abstract::Human cytoplasmic alpha-fetoprotein (AFP) has been classified as a member of the albuminoid gene family. The protein sequence of AFP has significant homology to that of human serum albumin (HSA), but its biological characteristics are vastly different from HSA. The AFP functions as a regulator in the phosphatidylinosi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/256916
更新日期:2015-01-01 00:00:00
abstract::Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3296437
更新日期:2016-01-01 00:00:00
abstract::This study evaluated the efficacy and safety of pulmonary rehabilitation (PR) for pneumoconiosis. We systematically searched PubMed, Embase, The Cochrane Library, Web of Science, SinoMed, CNKI, VIP databases and Wanfang Data from their inception to June 1, 2019. A systematic review and meta-analysis of randomized cont...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/6174936
更新日期:2020-07-28 00:00:00
abstract::A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1286480
更新日期:2018-11-13 00:00:00
abstract::Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE-/-) AS mice, which were trained by WBV (15 Hz, 30 m...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4934861
更新日期:2018-03-07 00:00:00
abstract::Gravity is crucial for spatial perception, postural equilibrium, and movement generation. The vestibular apparatus is the main sensory system involved in monitoring gravity. Hair cells in the vestibular maculae respond to gravitoinertial forces, but they cannot distinguish between linear accelerations and changes of h...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/615854
更新日期:2014-01-01 00:00:00
abstract::Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, ge...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3071013
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship of delivery type, maternal anesthesia, feeding modalities, and first feeding and meconium passage times with early bilirubin levels of healthy infants. METHODS:Cord, 24 hours' and 48 hours' total bilirubin levels were measured in 388 study infants. RESULTS:Infants born with c...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/316430
更新日期:2013-01-01 00:00:00
abstract::We discuss some aspects of the fluid dynamics of vitreous substitutes in the vitreous chamber, focussing on the flow induced by rotations of the eye bulb. We use simple, yet not trivial, theoretical models to highlight mechanical concepts that are relevant to understand the dynamics of vitreous substitutes and also to...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/672926
更新日期:2014-01-01 00:00:00
abstract::Diosmin has been widely used to treat patients with vascular pain for its potent anti-inflammatory and analgesic effects. To evaluate the therapeutic effects of Diosmin in the treatment of radicular pain, we conducted an investigator-initiated, randomized, active-controlled noninferiority trial between January 1, 2009...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2017/6875968
更新日期:2017-01-01 00:00:00
abstract::Immunodeficiency is associated with higher cancer incidence. However, it is unknown whether there is a link between immunodeficiency and development of multiple primary malignancies. In the present study we analyse this link focusing on kidney-transplanted patients, as they are at higher risk of developing cancer due ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/183523
更新日期:2015-01-01 00:00:00
abstract::Long noncoding RNAs play an essential role in bladder cancer progression. The role of long noncoding RNA EGFR-AS1 in bladder cancer needs further study. We used clinical specimens to analyze the relationship between EGFR-AS1 and bladder cancer patients' characteristics. The functional experiments and mechanism studies...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6665974
更新日期:2020-12-22 00:00:00
abstract::Quantitative magnetic resonance imaging (qMRI) is a promising approach to detect early cartilage degeneration. However, there is no consensus on which cartilage component contributes to the tissue's qMRI signal properties. T1, T1ρ, and T2⁎ maps of cartilage samples (n = 8) were generated on a clinical 3.0-T MRI system...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9460456
更新日期:2018-05-15 00:00:00
abstract::Platelets are anuclear cells and are devoid of genomic DNA, but they are capable of de novo protein synthesis from mRNA derived from their progenitor cells, megakaryocytes. There is mounting evidence that microRNA (miRNA) plays an important role in regulating gene expression in platelets. miR-223 is the most abundant ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/981841
更新日期:2015-01-01 00:00:00
abstract::One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/319589
更新日期:2015-01-01 00:00:00
abstract::After pancreatoduodenectomy, complication rates are up to 40%. To predict the risk of developing postoperative pancreatic fistula or severe complications, various factors were evaluated. 110 consecutive patients undergoing pancreatoduodenectomy at our institute between January 2012 and September 2014 with complete CT ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/824525
更新日期:2015-01-01 00:00:00
abstract::T. reesei is an efficient cellulase producer and biomass degrader. To improve xylitol production in Trichoderma reesei strains by genetic engineering, two approaches were used in this study. First, the presumptive D-xylulokinase gene in T. reesei (xyiH), which has high homology to known fungi D-xylulokinase genes, was...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/169705
更新日期:2014-01-01 00:00:00
abstract::Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5497402
更新日期:2016-01-01 00:00:00