Abstract:
:The incidence of acute kidney injury after cardiac surgery (CS-AKI) ranges from 33% to 94% and is associated with a high incidence of morbidity and mortality. The etiology is suggested to be multifactorial and related to almost all aspects of perioperative management. Numerous studies have reported the risk factors and risk scores and novel biomarkers of AKI have been investigated to facilitate the subclinical diagnosis of AKI. Based on the known independent risk factors, many preventive interventions to reduce the risk of CS-AKI have been tested. However, any single preventive intervention did not show a definite and persistent benefit to reduce the incidence of CS-AKI. Goal-directed therapy has been considered to be a preventive strategy with a substantial level of efficacy. Many pharmacologic agents were tested for any benefit to treat or prevent CS-AKI but the results were conflicting and evidences are still lacking. The present review will summarize the current updated evidences about the risk factors and preventive strategies for CS-AKI.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Shin SR,Kim WH,Kim DJ,Shin IW,Sohn JTdoi
10.1155/2016/2985148subject
Has Abstractpub_date
2016-01-01 00:00:00pages
2985148eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章,评审abstract::[This corrects the article DOI: 10.1155/2016/2643862.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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