Abstract:
:Background and Purposes. The 320-detector row CT scanner enables visualization of whole-brain hemodynamic information (dynamic CT angiography (CTA) derived from CT perfusion scans). However, arterial image quality in dynamic CTA (dCTA) is inferior to arterial image quality in standard CTA. This study evaluates whether the arterial image quality can be improved by using a total bolus extraction (ToBE) method. Materials and Methods. DCTAs of 15 patients, who presented with signs of acute cerebral ischemia, were derived from 320-slice CT perfusion scans using both the standard subtraction method and the proposed ToBE method. Two neurointerventionalists blinded to the scan type scored the arterial image quality on a 5-point scale in the 4D dCTAs in consensus. Arteries were divided into four categories: (I) large extradural, (II) intradural (large, medium, and small), (III) communicating arteries, and (IV) cerebellar and ophthalmic arteries. Results. Quality of extradural and intradural arteries was significantly higher in the ToBE dCTAs than in the standard dCTAs (extradural P = 0.001, large intradural P < 0.001, medium intradural P < 0.001, and small intradural P < 0.001). Conclusion. The 4D dCTAs derived with the total bolus extraction (ToBE) method provide hemodynamic information combined with improved arterial image quality as compared to standard 4D dCTAs.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Ghariq E,Mendrik AM,Willems PW,Joemai RM,Ghariq E,Vonken EJ,van Osch MJ,van Walderveen MAdoi
10.1155/2014/603173subject
Has Abstractpub_date
2014-01-01 00:00:00pages
603173eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
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