Potential Relationship between Clinical Significance and Serum Exosomal miRNAs in Patients with Multiple Myeloma.

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00

abstract：:Myosin VI (MVI) is a unique motor protein moving towards the minus end of actin filaments unlike other known myosins. Its important role has recently been postulated for striated muscle and myogenic cells. Since MVI functions through interactions of C-terminal globular tail (GT) domain with tissue specific partners, w...

journal_title：BioMed research international

authors： Karolczak J,Sobczak M,Skowronek K,Rędowicz MJ

更新日期：2015-01-01 00:00:00

abstract：AIM:To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS:The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazoliu...

journal_title：BioMed research international

authors： Sun G,Shi L,Yan S,Wan Z,Jiang N,Fu L,Li M,Guo J

更新日期：2014-01-01 00:00:00

abstract：:Cabbages (Brassica oleracea L.) are an important vegetable crop around world, and cold temperature is among the most significant abiotic stresses causing agricultural losses, especially in cabbage crops. Plant bZIP transcription factors play diverse roles in biotic/abiotic stress responses. In this study, 119 putative...

journal_title：BioMed research international

authors： Hwang I,Manoharan RK,Kang JG,Chung MY,Kim YW,Nou IS

更新日期：2016-01-01 00:00:00

abstract：:Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly(l-lactide-co-ε-caprolactone) (PLCL) scaffolds were printed by a 3D printing technology, low-temperature deposition manufacturing (LDM), and then PLCL scaffolds wer...

journal_title：BioMed research international

authors： He Y,Liu W,Guan L,Chen J,Duan L,Jia Z,Huang J,Li W,Liu J,Xiong J,Liu L,Wang D

更新日期：2018-02-28 00:00:00

abstract：:Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness amon...

journal_title：BioMed research international

authors： El Ghoul B,Daaboul Y,Korjian S,El Alam A,Mansour A,Hariri E,Samad S,Salameh P,Dahdah G,Blacher J,Safar ME,Aoun Bahous S

更新日期：2017-01-01 00:00:00

abstract：:Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in which synchronized hepatocyte proliferation is induced after massive liver mass loss. Hepatocyte proliferation could be regulated by multiple signals, such as miRNAs and autophagy, but underlying mechanism remains unclear....

journal_title：BioMed research international

authors： Lu T,Hao J,Shen C,Gu G,Zhang J,Xu N

更新日期：2018-07-31 00:00:00

abstract：:The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no suppleme...

journal_title：BioMed research international

authors： Siriussawakul A,Triyasunant N,Nimmannit A,Ngerncham S,Hirunkanokpan P,Luang-Aram S,Pechpaisit N,Wangdee A,Ruangvutilert P

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of applied suction during microkeratome-assisted laser in situ keratomileusis (LASIK) procedure on peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell-inner plexiform layer (GC-IPL) thickness. METHODS:89 patients (124 eyes) with established myopia ra...

journal_title：BioMed research international

authors： Zivkovic M,Jaksic V,Giarmoukakis A,Grentzelos M,Zlatanovic M,Zlatanovic G,Miljkovic A,Jovanovic S,Stamenkovic M,Kymionis G

更新日期：2017-01-01 00:00:00

abstract：:Moringa grows in the tropical and subtropical regions of the world. The genus Moringa belongs to family Moringaceae. It is found to possess various medicinal uses including hypoglycemic, analgesic, anti-inflammatory, hypolipidemic, and antioxidant activities. In this study, we investigated the antimicrobial and the an...

journal_title：BioMed research international

authors： Mansour M,Mohamed MF,Elhalwagi A,El-Itriby HA,Shawki HH,Abdelhamid IA

更新日期：2019-01-01 00:00:00

abstract：:Enteric fever caused by Salmonella enterica is a life-threatening systemic illness of gastrointestinal tract especially in tropical countries. Antimicrobial therapy is generally indicated but resistance towards commonly used antibiotics has limited their therapeutic usefulness. Therefore, we aimed to determine the ant...

journal_title：BioMed research international

authors： Khanal PR,Satyal D,Bhetwal A,Maharjan A,Shakya S,Tandukar S,Parajuli NP

更新日期：2017-01-01 00:00:00

abstract：:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...

journal_title：BioMed research international

authors： Deev RV,Drobyshev AY,Bozo IY,Isaev AA

更新日期：2015-01-01 00:00:00

abstract：:Recently published evidence has raised concerns about worse late mortality and increasing need for reintervention after off-pump coronary artery bypass grafting. We undertook this study to assess the impact of off-pump coronary artery bypass grafting on survival and freedom from reintervention at 10 years. From Januar...

journal_title：BioMed research international

authors： Raja SG,Husain M,Popescu FL,Chudasama D,Daley S,Amrani M

更新日期：2013-01-01 00:00:00

abstract：:Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been prop...

journal_title：BioMed research international

authors： Eisenbrey JR,Sridharan A,Liu JB,Forsberg F

更新日期：2015-01-01 00:00:00

abstract：:Gastric cancer is one of the most common cancers and the efficient therapeutic methods are limited. Further study of the exact molecular mechanism of gastric cancer to develop novel targeted therapies is necessary and urgent. We herein systematically examined that miR-204 suppressed both proliferation and metastasis o...

journal_title：BioMed research international

authors： Yuan X,Wang S,Liu M,Lu Z,Zhan Y,Wang W,Xu AM

更新日期：2017-01-01 00:00:00

abstract：:Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarra...

journal_title：BioMed research international

authors： Zhou Y,Zhao Y,Du H,Suo Y,Chen H,Li H,Liang X,Li Q,Huang X

更新日期：2020-01-02 00:00:00

abstract：:Selenium is an essential trace element, which has certain antioxidant properties. Na2SeO3 is toxic, and its use is limited. SeMet, as an organic selenium, is less toxic than Na2SeO3. In this experiment, different concentrations of Na2SeO3 and SeMet were added to MEA and PDA media to observe the effect of selenium on t...

journal_title：BioMed research international

authors： Zhao W,Zhai F,Han J

更新日期：2020-04-26 00:00:00

abstract：:The aim of our study was to monitor serum levels of two miRNAs (miR-21 and miR-141) and three KLKs (hK3/PSA, hK11, and hK13) before and 1, 5, and 30 days after radical prostatectomy, in order to characterize their fluctuations after surgery. 38 patients with prostate cancer were included. miR-21 and miR-141 were quant...

journal_title：BioMed research international

authors： Egidi MG,Cochetti G,Serva MR,Guelfi G,Zampini D,Mechelli L,Mearini E

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate the joint effects of the single nucleotide polymorphisms (SNPs) of genes in the folic acid pathway on homocysteine (Hcy) metabolism. METHODS:Four hundred women with normal pregnancies were enrolled in this study. SNPs were identified by MassARRAY. Serum folic acid and Hcy concentration were me...

journal_title：BioMed research international

authors： Liang S,Zhou Y,Wang H,Qian Y,Ma D,Tian W,Persaud-Sharma V,Yu C,Ren Y,Zhou S,Li X

更新日期：2014-01-01 00:00:00

abstract：:Objectives. To investigate the potential association of a set of serum cytokines with the severity of coronary artery disease (CAD). Methods. A total of 201 patients who underwent coronary angiography for chest discomfort were enrolled. The concentrations of serum IFN-γ, TNF-α, IL-2, IL-4, IL-6, IL-10, IL-9, and IL-17...

journal_title：BioMed research international

authors： Min X,Lu M,Tu S,Wang X,Zhou C,Wang S,Pang S,Qian J,Ge Y,Guo Y,Xu D,Cao K

更新日期：2017-01-01 00:00:00

abstract：:Little is known about how small variations in ionic currents and Ca²⁺ and Na⁺ diffusion coefficients impact action potential and Ca²⁺ dynamics in rabbit ventricular myocytes. We applied sensitivity analysis to quantify the sensitivity of Shannon et al. model (Biophys. J., 2004) to 5%-10% changes in currents conductanc...

journal_title：BioMed research international

authors： Lo YH,Peachey T,Abramson D,McCulloch A,Michailova A

更新日期：2013-01-01 00:00:00

abstract：:Heart disease is the leading cause of death worldwide. Therefore, assessing the risk of its occurrence is a crucial step in predicting serious cardiac events. Identifying heart disease risk factors and tracking their progression is a preliminary step in heart disease risk assessment. A large number of studies have rep...

journal_title：BioMed research international

authors： Jonnagaddala J,Liaw ST,Ray P,Kumar M,Dai HJ,Hsu CY

更新日期：2015-01-01 00:00:00

abstract：Introduction:Rapid eye movement sleep behavior disorder (RBD) is characterized by dream-enacting behavior (shouting, punching, and falling out of bed) related to unpleasant dreams and loss of normal rapid eye movement (REM) sleep muscle atonia. Rapid eye movement sleep enhances learning and memory by regulating neurona...

journal_title：BioMed research international

authors： Dagnew B,Dagne H,Andualem Z

更新日期：2020-05-15 00:00:00

abstract：Background:A deficiency in steroid 5α-reductase type 2 is an autosomal recessive disorder. Affected individuals manifested ambiguous genitalia, which is caused by decreased dihydrotestosterone (DHT) synthesis in the fetus. Methods:We analyzed 25 patients with 5α-reductase deficiency in China. Seventeen of the 25 patie...

journal_title：BioMed research international

authors： Han B,Cheng T,Zhu H,Yu J,Zhu WJ,Song HD,Yao H,Qiao J

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS:Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneou...

journal_title：BioMed research international

authors： Akashi M,Hashikawa K,Wanifuchi S,Kusumoto J,Shigeoka M,Furudoi S,Terashi H,Komori T

更新日期：2017-01-01 00:00:00

abstract：:Background. It has been suggested that, during pregnancy, endometriosis can cause a variety of disease-related complications. Objectives. The purpose of the study was to find out if women with histologically confirmed endometriosis do have a higher risk of adverse pregnancy outcome and if they suffer from a higher rat...

journal_title：BioMed research international

authors： Allerstorfer C,Oppelt P,Enzelsberger SH,Shamiyeh A,Schimetta W,Shebl OJ,Mayer RB

更新日期：2016-01-01 00:00:00

abstract：:Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-...

journal_title：BioMed research international

authors： Xu L,Sun Z,Fan Z

更新日期：2015-01-01 00:00:00

abstract：:Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

journal_title：BioMed research international

authors： He P,Hagiwara K,Chong H,Yu HH,Ito Y

更新日期：2015-01-01 00:00:00

abstract：:Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. The enhanced nitrative stress plays an important role in homocysteine-induced endothelial dysfunction. Previous studies have showed that phytoestrogen α -zearalanol alleviated endothelial injury in ovariectomized hyperhomocysteinemic rats;...

journal_title：BioMed research international

authors： Liu T,Hou DD,Zhao Q,Liu W,Zhen PP,Xu JP,Wang K,Huang HX,Li X,Zhang H,Xu HB,Wang W

更新日期：2013-01-01 00:00:00

abstract：Objective:To determine if increasing variability of blood pressure influences determination of cerebral autoregulation. Methods:A prospective observational study was performed at the ICU of a university hospital in the Netherlands. 13 comatose patients after cardiac arrest underwent baseline and intervention (tilting ...

journal_title：BioMed research international

authors： van den Brule JMD,van Kaam CR,van der Hoeven JG,Claassen JAHR,Hoedemaekers CWE

更新日期：2018-06-06 00:00:00