Abstract:
Background:Influenza virus mainly causes acute respiratory infections in humans. However, the diagnosis of influenza is not accurate based on clinical evidence, as the symptoms of flu are similar to other respiratory virus. The lateral-flow assay is a rapid method to detect influenza virus. But the effectiveness of the technique in detecting flu viruses is unclear. Hence, a meta-analysis would be performed to evaluate the accuracy of LFA in detecting influenza virus. Methods:Relevant literature was searched out in PubMed, Embase, Web of Science, and Cochrane Library databases with the keywords "lateral flow assay" and "flu virus". By Meta-DiSc software, pooled sensitivity, pooled specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), summary receiver operating characteristic curve (SROC), and area under the curve (AUC) can be calculated. Results:This meta-analysis contains 13 studies and 24 data. The pooled sensitivity and specificity of the influenza virus detected by LFA were 0.84 (95% CI: 0.82-0.86) and 0.97 (95% CI: 0.97-0.98), respectively. The pooled values of PLR, NLR, DOR, and SROC were 32.68 (17.16-62.24), 0.17 (0.13-0.24), 334.07 (144.27-773.53), and 0.9877. No publication bias was found. Conclusions:LFA exhibited high sensitivity and specificity in diagnosing influenza virus. It is a valuable alternative method which can diagnose influenza virus quickly. However, more evidence is required to confirm whether LFA is comparable to traditional methods for detecting the virus.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Han MY,Xie TA,Li JX,Chen HJ,Yang XH,Guo XGdoi
10.1155/2020/3969868subject
Has Abstractpub_date
2020-09-08 00:00:00pages
3969868eissn
2314-6133issn
2314-6141journal_volume
2020pub_type
杂志文章abstract::The characteristics of FDG uptake in the physiologic and malignant nasopharynx were investigated in the paper which was correlated with either pathologic findings or clinical follow-up. Three patients had pathologically established nasopharyngeal malignancy. In the 3 nasopharyngeal malignancies, 2 had diffusely and ex...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/354970
更新日期:2015-01-01 00:00:00
abstract::Chromosome/DNA instability could be one of the primary causes of malignant cell transformation. The objective of the present study was to evaluate the spontaneous genetic damages in exfoliated cells of buccal mucosa of head and neck cancer (HNC) by counting micronucleus (MN) and binucleated (BN) cells frequencies. MN ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/905252
更新日期:2013-01-01 00:00:00
abstract:Aims:We aimed to summarize available lines of evidence about intraoperative and postoperative donor outcomes following robotic-assisted laparoscopic donor nephrectomy (RALDN) as well as outcomes of graft and recipients. Methods:A systematic review of PubMed/Medline, ISI Web of Knowledge, and Scopus databases was perfo...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2019/1729138
更新日期:2019-04-22 00:00:00
abstract::Until now, the chemical bonding between titanium and bone has been examined only through a few mechanical detachment tests. Therefore, in this study, a sandblasted and acid-etched titanium mini-implant was removed from a human patient after 2 months of placement in order to identify the chemical integration mechanism ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/960410
更新日期:2015-01-01 00:00:00
abstract:Background:Large scalp defects, especially those complicated by calvarial defects, titanium mesh exposure, or cerebrospinal fluid (CSF) leak, pose a challenge for the neurosurgeon and plastic surgeon. Here, we describe our experience of reconstructing the complex scalp defect with free flap transfer. Methods:From Octo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2748219
更新日期:2020-01-10 00:00:00
abstract::Cardiotonic drugs mainly include digitalis, catecholamines, phosphodiesterase inhibitors, and calcium sensitizers, which have been successively discovered and applied in clinical practice. However, there are only a few new drugs available in this field, and the selection is very limited. Digitalis, catecholamines, and...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/9731467
更新日期:2019-09-19 00:00:00
abstract:OBJECTIVE:To evaluate the microshear bond strength (μSBS) of self-adhesive resin (SA) cement on leucite-reinforced glass-ceramic using silane or universal adhesive. MATERIALS AND METHODS:Ceramic blocks were etched with 9.5% hydrofluoric acid and divided into three groups (n = 16): (1) negative control (NC) without tre...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/361893
更新日期:2015-01-01 00:00:00
abstract::This study was performed to assess the efficacy and safety of a topical diclofenac solution in patients with knee osteoarthritis (OA). PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched for randomized controlled trials until June 2020. The WOMAC pain, stiffness, physical function subs...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1758071
更新日期:2020-11-24 00:00:00
abstract::This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/129629
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To explore the safety and efficacy of transpseudarthrosis osteotomy with interbody fusion in the treatment of Ankylosing Spondylitis (AS) patients with kyphotic spinal pseudarthrosis by a single posterior approach. METHODS:Twelve consecutive patients with spinal pseudarthrosis underwent transpseudarthrosis o...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/4079849
更新日期:2017-01-01 00:00:00
abstract::Contrast-induced nephropathy (CIN) remains a leading cause of iatrogenic acute kidney injury, as the usage of contrast media for imaging and intravascular intervention keeps expanding. Diabetes is an important predisposing factor for CIN, particularly in patients with renal functional impairment. Renal hypoxia, combin...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/123589
更新日期:2013-01-01 00:00:00
abstract:Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1204605
更新日期:2020-05-23 00:00:00
abstract::Background. The aim of this study was to assess the effects of low concentrations of H2O2 on angiogenesis of human umbilical vein endothelial cells (HUVECs) in vitro and explore the underlying mechanisms. Methods. HUVECs were cultured and stimulated with different concentrations of H2O2. Flow cytometric analysis was u...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/6895730
更新日期:2017-01-01 00:00:00
abstract::Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an i...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/761264
更新日期:2014-01-01 00:00:00
abstract::In vivo confocal microscopy (IVCM) of the living human cornea offers the ability to perform repeated imaging without tissue damage. Studies using corneal IVCM have led to significant contributions to scientific and clinical knowledge of the living cornea in health and pathological states. Recently the application of c...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/951081
更新日期:2015-01-01 00:00:00
abstract::Cognitive decline impacts older adults, particularly their independence. The goal of this project was to increase understanding of how short-term, everyday lifestyle options, including physical activity, help an older adult sustain cognitive independence. Using a secondary analysis of lifestyle choices, we drew on a d...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究
doi:10.1155/2016/7405748
更新日期:2016-01-01 00:00:00
abstract:Background:Salinity is one of the major abiotic constraints that hinder health and quality of crops. Conversely, halotolerant plant growth-promoting rhizospheric (PGPR) bacteria are considered biologically safe for alleviating salinity stress. Results:We isolated halotolerant PGPR strains from the rhizospheric soil of...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9530963
更新日期:2019-10-20 00:00:00
abstract::Hydrocephalus is a common neurological condition that can have traumatic ramifications and can be lethal without treatment. Nowadays, during therapy radiologists have to spend a vast amount of time assessing the volume of cerebrospinal fluid (CSF) by manual segmentation on Computed Tomography (CT) images. Further, som...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3059170
更新日期:2019-07-07 00:00:00
abstract:Objective:To retrospectively investigate computed tomographic (CT) quantitative analysis of ground-glass opacity (GGO) volume percentage and morphologic features of resected lung adenocarcinomas according to epidermal growth factor receptor (EGFR) mutation status and subtypes. Methods:Amplification refractory mutation...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9643836
更新日期:2019-03-06 00:00:00
abstract:OBJECTIVE:To analyze the clinical relevance of the levels of TNFα blockers and anti-drug antibodies (anti-drug Ab) in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) treated with adalimumab (ADA), etanercept (ETA), or infliximab (INF) for a prolonged period of time. METHODS:Clinical characteristics...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/604872
更新日期:2015-01-01 00:00:00
abstract::The classic assay for a large population biomass is time-consuming, labor intensive, and chemically expensive. This paper would find out a rapid assay for predicting biomass digestibility from biomass structural features without hydrolysis. We examined the 62 representative corn stover accessions that displayed a dive...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9167508
更新日期:2018-08-12 00:00:00
abstract::Effective alteration of the recalcitrance properties like crystallization of cellulose, lignin shield, and interlinking of lignocellulosic biomass is an ideal way to utilize the full-scale potential for biofuel production. This study exhibited three different pretreatment effects to enhance the digestibility of corn s...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2786598
更新日期:2016-01-01 00:00:00
abstract::Adult orthodontics may confront problems related to the bonding performance of orthodontic brackets to new generation restorative materials used for crown or laminate restorations. The aim of the present study was to investigate the shear bond strength of ceramic brackets to two new generation CAD/CAM interpenetrating...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1871598
更新日期:2018-05-30 00:00:00
abstract:Background:In resource limited settings, HIV/AIDS patients lack access to sufficient nutritious foods, which poses challenges to the success of antiretroviral therapy. HIV/AIDS and malnutrition are still major public health problems in Ethiopia. Though measuring nutritional status is an essential part of ART program, l...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1913534
更新日期:2018-05-06 00:00:00
abstract::Obesity or maternal overnutrition during pregnancy and lactation might have long-term consequences in offspring health. Fetal programming is characterized by adaptive responses to specific environmental conditions during early life stages. Programming alters gene expression through epigenetic modifications leading to ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/8061389
更新日期:2018-06-20 00:00:00
abstract::The present study was conducted to evaluate the effect of a Bacillus megaterium-coated diet on growth performance, digestive enzymes, and intestinal microbial diversity in Songpu mirror carp (Cyprinus specularis Songpu). The fish were manually fed two diets (a control diet and a B. megaterium-coated diet) three times ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8863737
更新日期:2020-11-13 00:00:00
abstract::Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/680615
更新日期:2015-01-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a systemic multifactorial autoimmune disorder. The interactions between diverse environmental and genetic factors lead to the onset of this complex autoimmune disorder. Serum levels of vitamin D (VD) are involved in the regulation of various immune responses. Vitamin D is a key signaling m...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/3494937
更新日期:2019-05-07 00:00:00
abstract::The aims of this study were to investigate the reasons of transfers from long-term care hospitals (LTCHs) to emergency departments (EDs) of university hospitals in geriatric patients and to categorize the avoidable causes of these transfers. This retrospective multicenter study involved patients aged 65 years and olde...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究
doi:10.1155/2019/7041607
更新日期:2019-06-19 00:00:00
abstract::Body weight supported locomotor training uses neuroplasticity principles to improve recovery following a spinal cord injury (SCI). Steady state locomotion using the same body weight support (BWS) percent was compared in 7 males (42.6 ± 4.29 years) with incomplete SCI and matched (gender, age) noninjured controls (42.7...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/632765
更新日期:2014-01-01 00:00:00