Radiopharmaceutical stem cell tracking for neurological diseases.

abstract：Background:Preeclampsia (PE) is a pregnancy-specific hypertension syndrome and is one of the leading causes of maternal and perinatal morbidity and mortality. Long noncoding RNAs (lncRNAs) have been reported to be abnormally expressed in many diseases, including preeclampsia. The present study is aimed at identifying t...

journal_title：BioMed research international

authors： Zhang Z,Wang P,Zhang L,Huang C,Gao J,Li Y,Yang B

更新日期：2020-06-05 00:00:00

abstract：:Polyetheretherketone (PEEK), which has biomechanical performance similar to that of human cancellous bone, is used widely as a spinal implant material. However, its bioinertness and hydrophobic surface properties result in poor osseointegration. This study applies a novel modification method, arc ion plating (AIP), th...

journal_title：BioMed research international

authors： Tsou HK,Chi MH,Hung YW,Chung CJ,He JL

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Most developmental processes are under the control of small regulatory RNAs called microRNAs (miRNAs). We hypothesize that different fetal developmental processes might be reflected by extracellular miRNAs in maternal plasma and may be utilized as biomarkers for the noninvasive prenatal diagnosis of chromoso...

journal_title：BioMed research international

authors： Kamhieh-Milz J,Moftah RF,Bal G,Futschik M,Sterzer V,Khorramshahi O,Burow M,Thiel G,Stuke-Sontheimer A,Chaoui R,Kamhieh-Milz S,Salama A

更新日期：2014-01-01 00:00:00

abstract：:Angiogenesis and lymphangiogenesis are important in the proliferation and survival of the malignant hematopoietic neoplasms, including non-Hodgkin's lymphomas (NHLs). Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) play an important role in the initiation of angiogenesis. Both VEGF ...

journal_title：BioMed research international

authors： Wróbel T,Mazur G,Dzietczenia J,Gębura K,Kuliczkowski K,Bogunia-Kubik K

更新日期：2013-01-01 00:00:00

abstract：:Light traps represent the most used attractive system to collect and monitor phlebotomine sand flies. Recent studies have suggested that light traps can be easily upgraded by the use of light-emitting diode (LED) with positive effects on trap design, weight, and battery life. However, scant data on the effect of diffe...

journal_title：BioMed research international

authors： Gaglio G,Napoli E,Arfuso F,Abbate JM,Giannetto S,Brianti E

更新日期：2018-06-27 00:00:00

abstract：:Aim. To refine the decellularization protocol of whole porcine liver, which holds great promise for liver tissue engineering. Methods. Three decellularization methods for porcine livers (1% sodium dodecyl sulfate (SDS), 1% Triton X-100 + 1% sodium dodecyl sulfate, and 1% sodium deoxycholate + 1% sodium dodecyl sulfate...

journal_title：BioMed research international

authors： Wu Q,Bao J,Zhou YJ,Wang YJ,Du ZG,Shi YJ,Li L,Bu H

更新日期：2015-01-01 00:00:00

abstract：:New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full-fledged annotation systems are usually home-grown and customized to a particular geno...

journal_title：BioMed research international

authors： Alioto T,Picardi E,Guigó R,Pesole G

更新日期：2013-01-01 00:00:00

abstract：:Individuals with X-HIGM syndrome fail to express functional CD40 ligand; consequently they cannot mount effective protective antibody responses against pathogenic bacteria. We evaluated, compared, and characterized the humoral immune response of wild type (WT) and C57-CD40L deficient (C57-CD40L(-/-)) mice infected wit...

journal_title：BioMed research international

authors： Lopez-Saucedo C,Bernal-Reynaga R,Zayas-Jahuey J,Galindo-Gomez S,Shibayama M,Garcia-Galvez C,Estrada-Parra S,Estrada-Garcia T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl2 on autophagy and muscle atrophy are still unclear. METHODS:C2C12 myotubes were exposed to increasing concentrat...

journal_title：BioMed research international

authors： Chen R,Jiang T,She Y,Xu J,Li C,Zhou S,Shen H,Shi H,Liu S

更新日期：2017-01-01 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：PURPOSE OF THE REPORT:There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role of (99m)Tc-ECD SPECT in a large number of subjects with craniosynostosis. MATERIALS AND METHODS:We prospectively analyzed a coh...

journal_title：BioMed research international

authors： Barik M,Bajpai M,Das RR,Malhotra A,Panda SS,Sahoo MK,Dwivedi S

更新日期：2014-01-01 00:00:00

abstract：:One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...

journal_title：BioMed research international

authors： Holczer M,Márton M,Kurucz A,Bánhegyi G,Kapuy O

更新日期：2015-01-01 00:00:00

abstract：:Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...

journal_title：BioMed research international

authors： Veryser L,Bracke N,Wynendaele E,Joshi T,Tatke P,Taevernier L,De Spiegeleer B

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Chemokine/receptor axis is a predominant actor of clinical disorders. They are key factors of pathogenesis of almost all clinical situations including asthma. Correspondingly, CXCL12 is involved in the immune responses. Therefore, this study was designed to explore the association between gene polymo...

journal_title：BioMed research international

authors： Rafatpanah H,Amin M,Ghasemshirazi M,Kazemiarababadi M,Khorramdelazad H,Abousaidi H,Shabani Z,Sayadi A,Hassanshahi G,Samadi J

更新日期：2013-01-01 00:00:00

abstract：Purpose:To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods:A retrospective analysis was conducted in 34 eyes from 24 progressive...

journal_title：BioMed research international

authors： Wang J,Li Z,Zhang H,Gao N,Mu G

更新日期：2019-04-03 00:00:00

abstract：OBJECTIVE:Radiopharmaceutical production process must adhere to current good manufacturing process (CGMP) compliance to ensure the quality of precursor, prodrug (active pharmaceutical ingredient, API), and the final drug product that meet acceptance criteria. We aimed to develop an automated system for production of CG...

journal_title：BioMed research international

authors： Chi YT,Chu PC,Chao HY,Shieh WC,Chen CC

更新日期：2014-01-01 00:00:00

abstract：:Cardiotonic drugs mainly include digitalis, catecholamines, phosphodiesterase inhibitors, and calcium sensitizers, which have been successively discovered and applied in clinical practice. However, there are only a few new drugs available in this field, and the selection is very limited. Digitalis, catecholamines, and...

journal_title：BioMed research international

authors： Pan J,Yang YM,Zhu JY,Lu YQ

更新日期：2019-09-19 00:00:00

abstract：:The aim was to evaluate three different biodegradable polylactic acid- (PLA-) based osteosynthesis materials (OM). These OM (BioSorb, LactoSorb, and Delta) were used in 64 patients of whom 55 (85.9%) had fractures of the zygoma, five (7.8%) in the LeFort II level, two of the frontal bone (3.1%), and two of the maxilla...

journal_title：BioMed research international

authors： Kolk A,Köhnke R,Saely CH,Ploder O

更新日期：2015-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are composed of a group of endogenous and noncoding small RNAs which control expression of complementary target mRNAs. The extended functions of miRNAs enhance the complexity of gene-regulatory processes in cardiovascular and cerebrovascular diseases. Indeed, recent studies have shown that miRNAs ar...

journal_title：BioMed research international

authors： Li M,Zhang J

更新日期：2015-01-01 00:00:00

abstract：:Models using large animals that are suitable for studying artificial liver support system (ALSS) are urgently needed. Presently available acute liver failure (ALF) models mainly involve pigs or dogs. Establishment of current surgical ALF models (hepatectomy/devascularization) requires either very good surgical skills ...

journal_title：BioMed research international

authors： Cai L,Weng J,Feng L,He G,Qin J,Zhang Z,Li Y,Peng Q,Jiang Z,Pan M,Gao Y

更新日期：2016-01-01 00:00:00

abstract：:ELABELA (ELA) is considered to be implicated in the pathophysiology of preeclampsia (PE), since ELA-deficient mice exhibited PE-like symptoms and infusion of exogenous ELA normalized the gestational hypertension (GH) and proteinuria. However, no evidence show that circulating ELA is deficient in early placental develo...

journal_title：BioMed research international

authors： Ma S,Guo C,Zhang J,Long S,Tan H,You Y

更新日期：2020-09-28 00:00:00

abstract：:Healthcare professionals undergo high levels of occupational stress as a result of their working conditions. Thus, the aim of this study is to develop a model that focuses on healthcare professionals so as to analyze the influence that job demands, control, social support, and recognition have on the likelihood that a...

journal_title：BioMed research international

authors： García-Herrero S,Lopez-Garcia JR,Herrera S,Fontaneda I,Báscones SM,Mariscal MA

更新日期：2017-01-01 00:00:00

abstract：:We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

journal_title：BioMed research international

authors： Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate, at a laboratory scale, the ability of this microorganism to grow in seawater and bioaccumulate in mussels (Mytilus galloprovincialis) maintained in constantly aerated tanks, containing twenty litres of artificial seawater. Three concentrations of A. butzleri LMG 10828(T) were tes...

journal_title：BioMed research international

authors： Ottaviani D,Chierichetti S,Rocchegiani E,Bartolini C,Masini L,Santarelli S,Leoni F

更新日期：2013-01-01 00:00:00

abstract：:Objectives. To investigate the potential association of a set of serum cytokines with the severity of coronary artery disease (CAD). Methods. A total of 201 patients who underwent coronary angiography for chest discomfort were enrolled. The concentrations of serum IFN-γ, TNF-α, IL-2, IL-4, IL-6, IL-10, IL-9, and IL-17...

journal_title：BioMed research international

authors： Min X,Lu M,Tu S,Wang X,Zhou C,Wang S,Pang S,Qian J,Ge Y,Guo Y,Xu D,Cao K

更新日期：2017-01-01 00:00:00

abstract：:Previous study showed that East Asian mtDNA haplogroups, especially those of Koreans, could be successfully assigned by the coupled use of analyses on coding region SNP markers and control region mutation motifs. In this study, we tried to see if the same triple multiplex analysis for coding regions SNPs could be also...

journal_title：BioMed research international

authors： Oh CS,Lee SD,Kim YS,Shin DH

更新日期：2015-01-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial ...

journal_title：BioMed research international

authors： Osayi SN,Bloomston M,Schmidt CM,Ellison EC,Muscarella P

更新日期：2014-01-01 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：:Objectives. This study aimed to determine the feasibility of cochlear implantation for sensorineural hearing loss in patients with Waardenburg syndrome. Method. A retrospective chart review was performed on patients who underwent cochlear implantation at the University of Tokyo Hospital. Clinical classification, genet...

journal_title：BioMed research international

authors： Koyama H,Kashio A,Sakata A,Tsutsumiuchi K,Matsumoto Y,Karino S,Kakigi A,Iwasaki S,Yamasoba T

更新日期：2016-01-01 00:00:00

abstract：:The regiospecific characteristics of n-3 polyunsaturated fatty acids (PUFAs) in triacylglycerol (TAG) significantly affect the physicochemical and physiological properties of marine fish oils. In this study, the TAG molecular species composition and positional distributions of fatty acids were investigated in three ma...

journal_title：BioMed research international

authors： Zhang H,Zhao H,Zhang Y,Shen Y,Su H,Jin J,Jin Q,Wang X

更新日期：2018-07-10 00:00:00