Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Cardiovascular and Cerebrovascular Diseases.

abstract：Background and Aim:The incidence of nonalcoholic fatty liver disease (NAFLD) as a metabolic disease is increasing annually. In the present study, we aimed to explore the influence of NAFLD on the severity of acute pancreatitis (AP). Methods:The severity of AP was diagnosed and analyzed according to the 2012 revised At...

journal_title：BioMed research international

authors： Wu D,Zhang M,Xu S,Wu K,Wang N,Wang Y,Wu J,Lu G,Gong W,Ding Y,Xiao W

更新日期：2019-01-22 00:00:00

abstract：:Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The more rationale approach to delay the progression of sarcopenia is based on the combination of proper nutrition, possibly associated with the use of dietary supplements and a regular exercise program. ...

journal_title：BioMed research international

authors： Rondanelli M,Faliva M,Monteferrario F,Peroni G,Repaci E,Allieri F,Perna S

更新日期：2015-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：:Background. High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjec...

journal_title：BioMed research international

authors： Rondanelli M,Giacosa A,Morazzoni P,Guido D,Grassi M,Morandi G,Bologna C,Riva A,Allegrini P,Perna S

更新日期：2016-01-01 00:00:00

abstract：:Diabetic foot ulcers (DFUs) are characterized by an unsatisfactory inflammatory and migratory response. Skin inflammation involves the participation of many cells and particularly macrophages. Macrophage function can be modulated by neuropeptides; however, little is known regarding the role of neurotensin (NT) as a mo...

journal_title：BioMed research international

authors： Moura LI,Silva L,Leal EC,Tellechea A,Cruz MT,Carvalho E

更新日期：2013-01-01 00:00:00

abstract：:Transient receptor potential polycystic 2 (TRPP2) exerts vital roles in various types of cancer; however, its underlying mechanisms remain largely unknown. This study is aimed at investigating whether knockdown of TRPP2 affected the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) signaling pathway and...

journal_title：BioMed research international

authors： Li K,Chen L,Lin Z,Zhu J,Fang Y,Du J,Shen B,Wu K,Liu Y

更新日期：2020-11-14 00:00:00

abstract：Objective:Study the effect of quality control circle (QCC) in promoting the usage of rubber dams (RD) in root canal treatment of chronic pulpitis in primary teeth. Methods:Set up a quality control group to increase the amount of rubber dams used in the treatment of chronic pulpitis in primary teeth. Monthly monitoring...

journal_title：BioMed research international

authors： Jingxian F,Yang L,Qiong L,Hong Q,Hedi L,Jinglan Z,Fang L,Jing Y,Xiaoming W,Yingying S

更新日期：2020-02-24 00:00:00

abstract：BACKGROUND AND PURPOSE:Primary malignant spine/spinal tumors (PMSTs) are rare and life-threatening diseases. In this study, we demonstrated the advantage of volume-based 18F-FDG PET/CT metabolic parameter, metabolic tumor volume (MTV), for assessing the aggressiveness of PMSTs. MATERIALS AND METHODS:We retrospectively...

journal_title：BioMed research international

authors： Matsumoto Y,Baba S,Endo M,Setsu N,Iida K,Fukushi JI,Kawaguchi K,Okada S,Bekki H,Isoda T,Kitamura Y,Honda H,Nakashima Y

更新日期：2017-01-01 00:00:00

abstract：Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...

journal_title：BioMed research international

authors： Satomi S,Kakuta N,Murakami C,Sakai Y,Tanaka K,Tsutsumi YM

更新日期：2018-05-15 00:00:00

abstract：:Aerobic granulation of activated sludge was successfully achieved in a full-scale sequencing batch reactor (SBR) with 50,000 m(3) d(-1) for treating a town's wastewater. After operation for 337 days, in this full-scale SBR, aerobic granules with an average SVI30 of 47.1 mL g(-1), diameter of 0.5 mm, and settling veloc...

journal_title：BioMed research international

authors： Li J,Ding LB,Cai A,Huang GX,Horn H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Osteopontin (OPN), a multifunctional glycoprotein secreted from a wide variety of cells after inflammatory stimulation, is well accepted to contribute to the development of allergic diseases. However, the influence of histamine H1 receptor antagonists (antihistamines) on OPN functions is not well understood....

journal_title：BioMed research international

authors： Komatsuzaki T,Suzaki I,Hirano K,Kanai K,Asano K,Suzaki H

更新日期：2013-01-01 00:00:00

abstract：:Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on IL-6-induced STAT3 e...

journal_title：BioMed research international

authors： Jang HJ,Lee SJ,Lim HJ,Jung K,Lee S,Park CS,Lee SW,Rho MC

更新日期：2018-06-10 00:00:00

abstract：:Correlation of parametrized image texture features (ITF) analyses conducted in different regions of interest (ROIs) overcomes limitations and reliably reflects image quality. The aim of this study is to propose a nonparametrical method and classify the quality of a magnetic resonance (MR) image that has undergone cont...

journal_title：BioMed research international

authors： Obuchowicz R,Piórkowski A,Urbanik A,Strzelecki M

更新日期：2019-11-20 00:00:00

abstract：:Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...

journal_title：BioMed research international

authors： Matar KM

更新日期：2013-01-01 00:00:00

abstract：:Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...

journal_title：BioMed research international

authors： Gou H,Ye J,Wang Y,Xu X,Shen Q,Xue J,Zhao J,Lu X

更新日期：2017-01-01 00:00:00

abstract：:This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...

journal_title：BioMed research international

authors： Abdel Aziz MT,Khaled HM,El Hindawi A,Roshdy NK,Rashed LA,Sabry D,Hassouna AA,Taha F,Ali WI

更新日期：2013-01-01 00:00:00

abstract：:No pharmacological treatment is currently available to protect brain from neuronal damage after ischemic stroke. Recent studies found that enkephalin may play an important role in neuron regeneration. We assembled a homogeneous size vesicle constituted by transferrin, exosomes, and enkephalin. Immunofluorescence assay...

journal_title：BioMed research international

authors： Liu Y,Fu N,Su J,Wang X,Li X

更新日期：2019-03-04 00:00:00

abstract：:The most expedient unit of the human body is its cell. Encapsulated within the cell are many infinitesimal entities and molecules which are protected by a cell membrane. The proteins that are associated with this lipid based bilayer cell membrane are known as membrane proteins and are considered to play a significant ...

journal_title：BioMed research international

authors： Butt AH,Khan SA,Jamil H,Rasool N,Khan YD

更新日期：2016-01-01 00:00:00

abstract：Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

journal_title：BioMed research international

authors： Jin X,Niu Y,Gu W,Wang J

更新日期：2020-08-10 00:00:00

abstract：:Macleaya cordata extract is of great scientific and practical interest to researchers, due to its antimicrobial and anti-inflammatory responses within experimental animals. This study was designed to determine the diarrhea score and innate immunity of growing piglets after they had received Macleaya cordata extract su...

journal_title：BioMed research international

authors： Liu G,Guan G,Fang J,Martínez Y,Chen S,Bin P,Duraipandiyan V,Gong T,Tossou MC,Al-Dhabi NA,Yin Y

更新日期：2016-01-01 00:00:00

abstract：:Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and the constancy of the ionic product for water. These rules define the acid-base balance in the human body. According to the electroneutrality principle, plasma has to be electrically neutral and th...

journal_title：BioMed research international

authors： Adeva-Andany MM,Carneiro-Freire N,Donapetry-García C,Rañal-Muíño E,López-Pereiro Y

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the relation between the sensory and anthropometric variables in the quiet standing. METHODS:One hundred individuals (50 men, 50 women; 20-40 years old) participated in this study. For all participants, the body composition (fat tissue, lean mass, bone mineral content, ...

journal_title：BioMed research international

authors： Alonso AC,Mochizuki L,Silva Luna NM,Ayama S,Canonica AC,Greve JM

更新日期：2015-01-01 00:00:00

abstract：:This study aimed at clarifying the mechanism and role of survivin in hypoxia-induced multidrug resistance (MDR) of laryngeal carcinoma cells. Human laryngeal cancer cells were incubated under hypoxia or normoxia. The expression of survivin was silenced by performing RNA interference. Additionally, by Western blot and ...

journal_title：BioMed research international

authors： Xu D,Li DW,Xie J,Chen XW

更新日期：2019-04-24 00:00:00

abstract：:Although cases of Mediterranean spotted fever (MSF) have been reported for decades in southeastern Romania, there are few published data. We retrospectively studied 339 patients, diagnosed with MSF at the National Institute of Infectious Diseases "Prof. Dr. Matei Bals" between 2000 and 2011, in order to raise awarenes...

journal_title：BioMed research international

authors： Pitigoi D,Olaru ID,Badescu D,Rafila A,Arama V,Hristea A

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To identify an effective method to prevent myopia progression by characterizing the regulation of matrix metalloproteinase- (MMP-) 2 expression and its secretion from scleral fibroblasts and retinal pigment epithelium (RPE) cells by miR-29a. METHODS:The effects of miR-29a on the growth of scleral fibroblasts a...

journal_title：BioMed research international

authors： Zhang Y,Hu DN,Zhu Y,Sun H,Gu P,Zhu D,Zhou J

更新日期：2017-01-01 00:00:00

abstract：:Objectives. To investigate the protective effects of tropisetron on acetaminophen- (APAP-) induced liver injury in a mice model. Methods. C57BL/6 male mice were given tropisetron (0.3 to 10 mg/kg) 30 minutes before a hepatotoxic dose of acetaminophen (300 mg/kg) intraperitoneally. Twenty hours after APAP intoxication,...

journal_title：BioMed research international

authors： Liu FC,Lee HC,Liao CC,Li AH,Yu HP

更新日期：2016-01-01 00:00:00

abstract：:During vertebrate development, the lung inaugurates as an endodermal bud from the primitive foregut. Dichotomous subdivision of the bud results in arborizing airways that form the prospective gas exchanging chambers, where a thin blood-gas barrier (BGB) is established. In the mammalian lung, this proceeds through conv...

journal_title：BioMed research international

authors： Makanya A,Anagnostopoulou A,Djonov V

更新日期：2013-01-01 00:00:00

abstract：:Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carrier (NLC) to produce...

journal_title：BioMed research international

authors： Foong JN,Selvarajah GT,Rasedee A,Rahman HS,How CW,Beh CY,Teo GY,Ku CL

更新日期：2018-10-15 00:00:00

abstract：:Immunomodulatory agents have been proposed as therapeutic candidates to improve outcomes in sepsis. Transferon™, a dialyzable leukocyte extract (DLE), has been supported in Mexico as an immunomodulatory adjuvant in anti-infectious therapy. Here we present a retrospective study describing the experience of a referral p...

journal_title：BioMed research international

authors： Castrejón Vázquez MI,Reséndiz-Albor AA,Ynga-Durand MA,Arciniega Martínez IM,Orellana-Villazon VI,García López CA,Laue Noguera ML,Vargas Camaño ME

更新日期：2019-06-23 00:00:00

abstract：:Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...

journal_title：BioMed research international

authors： de Frias UA,Pereira GKB,Guazzaroni ME,Silva-Rocha R

更新日期：2018-07-09 00:00:00