Imbalance of the nerve growth factor and its precursor as a potential biomarker for diabetic retinopathy.

abstract：:Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an i...

journal_title：BioMed research international

authors： Rahal A,Kumar A,Singh V,Yadav B,Tiwari R,Chakraborty S,Dhama K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：Background:Currently, effective genetic markers are limited to predict the clinical outcome of melanoma. High-throughput multiomics sequencing data have provided a valuable approach for the identification of genes associated with cancer prognosis. Method:The multidimensional data of melanoma patients, including clinic...

journal_title：BioMed research international

authors： Gao Y,Li Y,Niu X,Wu Y,Guan X,Hong Y,Chen H,Song B

更新日期：2020-05-08 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：:A reliable in vivo imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. Most stem cell transplantation studies have used immunohistological staining, which does not provide information about the migration of transplanted cells in vivo in the...

journal_title：BioMed research international

authors： Kim JH,Lee HJ,Song YS

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Hypertension and hypervolemia relationship was proven among renal disease, although it is not known in normal population. Present study determines the fluid distribution defects in relation to blood pressure. MATERIAL AND METHODS:In a population-based survey in Turkey demographics, height, weight, blood pre...

journal_title：BioMed research international

authors： Hür E,Özişik M,Ural C,Yildiz G,Mağden K,Köse SB,Köktürk F,Büyükuysal Ç,Yildirim I,Süleymanlar G,Ateş K,Duman S

更新日期：2014-01-01 00:00:00

abstract：AIM:To evaluate the impact of SPARC on female sexual function. METHODS:151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. A minim...

journal_title：BioMed research international

authors： Al-Ali BM,Shamloul R,Hutterer GC,Puchwein E,Pummer K,Avian A,Primus G

更新日期：2013-01-01 00:00:00

abstract：:Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...

journal_title：BioMed research international

authors： Caimmi M,Guanziroli E,Malosio M,Pedrocchi N,Vicentini F,Molinari Tosatti L,Molteni F

更新日期：2015-01-01 00:00:00

abstract：:Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentione...

journal_title：BioMed research international

authors： Tai CL,Lai PL,Lin WD,Tsai TT,Lee YC,Liu MY,Chen LH

更新日期：2016-01-01 00:00:00

abstract：:Progression of idiopathic dilated cardiomyopathy (IDCM) is marked with extensive left ventricular remodeling whose clinical manifestations and molecular basis are poorly understood. We aimed to evaluate the clinical potential of titin ligands in monitoring progression of cardiac remodeling associated with end-stage ID...

journal_title：BioMed research international

authors： Bogomolovas J,Brohm K,Čelutkienė J,Balčiūnaitė G,Bironaitė D,Bukelskienė V,Daunoravičus D,Witt CC,Fielitz J,Grabauskienė V,Labeit S

更新日期：2015-01-01 00:00:00

abstract：:Cardiovascular diseases (CVDs) are considered to be the predominant cause of death in the world. Chinese herb medicines (CHMs) have been widely used for the treatment of CVDs in Asian countries for thousands of years. One reason of high efficacy of CHMs in treating CVDs is attributed to their inhibition in atheroscler...

journal_title：BioMed research international

authors： Lu L,Sun X,Qin Y,Guo X

更新日期：2018-06-13 00:00:00

abstract：:Hilar cholangiocarcinoma (HCC) remains one of the most difficult tumors to stage and treat. The aim of the study was to assess the diagnostic efficiency of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computer tomography (PET/CT) in evaluating the resectability of HCC. A...

journal_title：BioMed research international

authors： Zhang H,Zhu J,Ke F,Weng M,Wu X,Li M,Quan Z,Liu Y,Zhang Y,Gong W

更新日期：2015-01-01 00:00:00

abstract：:CA-125 has been a valuable marker for the follow-up of ovarian cancer patients but it is not sensitive enough to be used as diagnostic marker. We had already used secretomic methods to identify proteins differentially secreted by serous ovarian cancer cells compared to healthy ovarian cells. Here, we evaluated the sec...

journal_title：BioMed research international

authors： Kramer M,Pierredon S,Ribaux P,Tille JC,Petignat P,Cohen M

更新日期：2015-01-01 00:00:00

abstract：:The aims of this study were to evaluate the contribution of chromosomal microarray analysis (CMA) in the prenatal diagnosis of fetuses with central nervous system (CNS) anomalies but normal chromosomal karyotype. A total of 46 fetuses with CNS anomalies with or without other ultrasound anomalies but normal karyotypes ...

journal_title：BioMed research international

authors： Sun L,Wu Q,Jiang SW,Yan Y,Wang X,Zhang J,Liu Y,Yao L,Ma Y,Wang L

更新日期：2015-01-01 00:00:00

abstract：:Cigarette smoke is highly toxic, and it can promote increased production of reactive species and inflammatory response and leads to liver diseases. Quercetin is a flavonoid that displays antioxidant and anti-inflammatory activities in liver diseases. This study aimed at evaluating the protective effects of quercetin o...

journal_title：BioMed research international

authors： Machado-Junior PA,Araújo NPS,Souza ABF,Castro TF,Oliveira M,Costa GP,Matos NA,Vieira PMA,Talvani A,Bezerra FS,Cangussú SD

更新日期：2020-11-15 00:00:00

abstract：:Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged o...

journal_title：BioMed research international

authors： Song Y,Zhao Y,Wang F,Tao L,Xiao J,Yang C

更新日期：2014-01-01 00:00:00

abstract：:Dysfunctions of chaperone-mediated autophagy (CMA), the main catabolic pathway for alpha-synuclein, have been linked to the pathogenesis of Parkinson's disease (PD). Since till now there is limited information on how PD-related toxins may affect CMA, in this study we explored the effect of mitochondrial complex I inhi...

journal_title：BioMed research international

authors： Sala G,Arosio A,Stefanoni G,Melchionda L,Riva C,Marinig D,Brighina L,Ferrarese C

更新日期：2013-01-01 00:00:00

abstract：:High-dose melphalan (200 mg/m(2)) as conditioning regimen followed by autologous stem cell transplantation (ASCT) rescue has been established as a standard treatment for patients with multiple myeloma (MM) younger than 65 years of age. However, the role of ASCT in elderly patients older than 65 years remains controver...

journal_title：BioMed research international

authors： Ozaki S,Shimizu K

更新日期：2014-01-01 00:00:00

abstract：:Alzheimer's disease (AD) and multiple sclerosis are major neurodegenerative diseases, which are characterized by the accumulation of abnormal pathogenic proteins due to oxidative stress, mitochondrial dysfunction, impaired autophagy, and pathogens, leading to neurodegeneration and behavioral deficits. Herein, we revie...

journal_title：BioMed research international

authors： Tandon A,Singh SJ,Chaturvedi RK

更新日期：2018-07-12 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Perimesencephalic nonaneurysmal subarachnoid hemorrhage (PM-NASAH) is characterized by a benign course compared with aneurysmal SAH. While vasospasm (VS) after aneurysmal SAH is considered responsible for serious complications, VS post-PM-NASAH is not well documented. Our purpose was to characterize the inci...

journal_title：BioMed research international

authors： Prat D,Goren O,Bruk B,Bakon M,Hadani M,Harnof S

更新日期：2013-01-01 00:00:00

abstract：:The regulation of transcriptome expression level is a complex process involving multiple-level interactions among molecules such as protein coding RNA (mRNA), long noncoding RNA (lncRNA), and microRNA (miRNA), which are essential for the transcriptome stability and maintenance and regulation of body homeostasis. The a...

journal_title：BioMed research international

authors： Liu C,Zhang YH,Deng Q,Li Y,Huang T,Zhou S,Cai YD

更新日期：2017-01-01 00:00:00

abstract：Introduction:SATIS-Stroke was developed to measure satisfaction regarding activities and participation among stroke survivors based on the concepts contained in the International Classification of Functioning, Disability, and Health. However, this measure is only available in English and French. Objective:Perform the ...

journal_title：BioMed research international

authors： Pereira GS,Silva SM,Júlio CE,Thonnard JL,Bouffioulx E,Corrêa JCF,Corrêa FI

更新日期：2019-02-18 00:00:00

abstract：:C-type lectins are multifunctional sugar-binding molecules expressed on dendritic cells (DCs) and macrophages that internalize antigens for processing and presentation. Macrophage galactose-type lectin 1 (MGL1) recognizes glycoconjugates expressing Lewis X structures which contain galactose residues, and it is selecti...

journal_title：BioMed research international

authors： Montero-Barrera D,Valderrama-Carvajal H,Terrazas CA,Rojas-Hernández S,Ledesma-Soto Y,Vera-Arias L,Carrasco-Yépez M,Gómez-García L,Martínez-Saucedo D,Becerra-Díaz M,Terrazas LI

更新日期：2015-01-01 00:00:00

abstract：:In clinical endodontics, preoperative estimation of root canal curvature is crucial regarding the prevention of iatrogenic errors. Reproduction of the two-dimensional radiographic images causes certain proximal view curvatures not seen. Therefore, the present study is aimed at investigating the degree of root canal cu...

journal_title：BioMed research international

authors： Faraj BM

更新日期：2021-01-13 00:00:00

abstract：:Background. High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjec...

journal_title：BioMed research international

authors： Rondanelli M,Giacosa A,Morazzoni P,Guido D,Grassi M,Morandi G,Bologna C,Riva A,Allegrini P,Perna S

更新日期：2016-01-01 00:00:00

abstract：:Epidemiological studies have proven an association between consumption of polyphenols and prevention of Alzheimer's disease, the most common form of dementia characterized by extracellular deposition of amyloid beta plaques. The aim of this study is pharmacological screening of the aqueous alcohol extract of Markhamia...

journal_title：BioMed research international

authors： Hassaan Y,Handoussa H,El-Khatib AH,Linscheid MW,El Sayed N,Ayoub N

更新日期：2014-01-01 00:00:00

abstract：:This investigation was aimed at assessing a possible interaction of a traditional Thai herbal recipe, "Ya-Sa-Marn-Phlae (YSMP)," used for wound treatments with topical antiseptics, povidone-iodine (PI) solution and hydrogen peroxide (H2O2), and effects of THR-SK010 alone and the combinations on Staphylococcus aureus. ...

journal_title：BioMed research international

authors： Chusri S,Tongrod S,Chokpaisarn J,Limsuwan S,Voravuthikunchai SP

更新日期：2014-01-01 00:00:00

abstract：:The p53-related p63 gene encodes multiple protein isoforms, which are involved in a variety of biological activities. p63 protein stability is mainly regulated by the ubiquitin-dependent proteasomal degradation pathway. Several ubiquitin E3 ligases have been identified and some protein kinases as well as other kinds o...

journal_title：BioMed research international

authors： Li C,Xiao ZX

更新日期：2014-01-01 00:00:00

abstract：:The aim of the present study is to analyse the secondary bacterial infections in a large group of patients with seasonal influenza A and influenza A(H1N1) pdm09. Patients diagnosed with seasonal influenza A and influenza A(H1N1) pdm09 between 2005 and 2009 were enrolled in the study. Data was retrieved from medical re...

journal_title：BioMed research international

authors： Liderot K,Ahl M,Ozenci V

更新日期：2013-01-01 00:00:00