Spider silk as guiding biomaterial for human model neurons.

abstract：Objective:The aim of this study was to investigate the association between adiponectin gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 and environmental risk factors of type 2 diabetes mellitus (T2DM) in Hohhot. The study explored different models of gene-environment interactions, aimed at p...

journal_title：BioMed research international

authors： Cui M,Gao Y,Zhao Y,Pang H,Chen L,Wang Z,Zhao L,Li M

更新日期：2020-06-21 00:00:00

abstract：:Removal of MTA from dentin by applying 37% hydrochloric acid (HCl) to reduce microhardness and push-out bond strength. Forty dentin slices were filled with WMTA and divided into two groups (n = 20). Ten slices remained untreated while others were exposed to either HCl or phosphate buffer saline (PBS) and all samples w...

journal_title：BioMed research international

authors： Saghiri MA,Garcia-Godoy F,Gutmann JL,Sheibani N,Asatourian A,Lotfi M,Elyasi M

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/4671349.]. ...

journal_title：BioMed research international

authors： Dhahri H,Rahmany I,Mahmood A,Al Maghayreh E,Elkilani W

更新日期：2020-06-30 00:00:00

abstract：:RRM2B gene encodes ribonucleoside-diphosphate reductase subunit M2 B, the p53-inducible small subunit (p53R2) of ribonucleotide reductase (RNR), an enzyme catalyzing dNTP synthesis for mitochondrial DNA. Defects in this gene may cause severe mitochondrial disease affecting mainly the nervous system. This study is aime...

journal_title：BioMed research international

authors： Ait El Cadi C,Krami AM,Charoute H,Elkarhat Z,Sifeddine N,Lakhiari H,Rouba H,Barakat A,Nahili H

更新日期：2020-07-25 00:00:00

abstract：:The influence of biomimetic calcium phosphate coating on osteoblasts behavior in vitro is not well established yet. In this study, we investigated the behavior of osteoblastic rat osteosarcoma 17/2.8 cells (ROS17/2.8) on two groups of biomaterial surfaces: alkaline-treated titanium surface (ATT) and biomimetic calcium...

journal_title：BioMed research international

authors： Yu X,Wei M

更新日期：2013-01-01 00:00:00

abstract：:Porcine circovirus virus type II (PCV2) is the etiology of postweaning multisystemic wasting syndrome (PMWS), porcine dermatitis, nephropathy syndrome (PDNS), and necrotizing pneumonia. Rapid diagnosis tool for detection of PCV2 plays an important role in the disease control and eradication program. Recombinase polyme...

journal_title：BioMed research international

authors： Yang Y,Qin X,Sun Y,Cong G,Li Y,Zhang Z

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To evaluate tumor structure in children with diffuse intrinsic pontine glioma (DIPG) using histogram analyses of mean diffusivity (MD), determine potential treatment and corticosteroid-related effects on MD, and monitor changes in MD distributions over time. MATERIALS AND METHODS:DTI was performed on a 1.5T GE...

journal_title：BioMed research international

authors： Steffen-Smith EA,Sarlls JE,Pierpaoli C,Shih JH,Bent RS,Walker L,Warren KE

更新日期：2014-01-01 00:00:00

abstract：Background:Inconsistent data have been reported for the effectiveness of intramuscular botulinum toxin type A (BTXA) in patients with limb spasticity after stroke. This meta-analysis of available randomized controlled trials (RCTs) aimed to determine the efficacy and safety of BTXA in adult patients with upper and lowe...

journal_title：BioMed research international

authors： Sun LC,Chen R,Fu C,Chen Y,Wu Q,Chen R,Lin X,Luo S

更新日期：2019-04-07 00:00:00

abstract：:DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu elements is an impor...

journal_title：BioMed research international

authors： Luo Y,Lu X,Xie H

更新日期：2014-01-01 00:00:00

abstract：:The pathogenesis of intractable epilepsy is not fully clear. In recent years, both animal and clinical trials have shown that the expression of ATP-binding cassette (ABC) transporters is increased in patients with intractable epilepsy; additionally, epileptic seizures can lead to an increase in the number of sites tha...

journal_title：BioMed research international

authors： Xiong J,Mao DA,Liu LQ

更新日期：2015-01-01 00:00:00

abstract：:Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...

journal_title：BioMed research international

authors： Tuttle R,Nurkin SJ,Hochwald SN

更新日期：2014-01-01 00:00:00

abstract：:A role of pro- and antioxidants for reducing rectal cancer (RC) incidence in operative, preoperative, and postoperative treatments is still disputable and controversial. The redox state of venous blood and tissues of blood vessels of 60 patients with RC (T2-4N0-2M0G2) and 20 donors is studied by means of the conventio...

journal_title：BioMed research international

authors： Burlaka AP,Vovk AV,Burlaka AA,Gafurov MR,Iskhakova KB,Lukin SN

更新日期：2018-08-13 00:00:00

abstract：:This study described a TaqMan based real-time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = -3.249...

journal_title：BioMed research international

authors： Chen R,Chen Q,Wu X,Che Y,Wang C,Wang L,Yan S,Zhou L

更新日期：2020-01-10 00:00:00

abstract：Objective:The objective was to study the risk and protective factors involved in retinal vascular development of preterm infants with retinopathy of prematurity. Methods:Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of prematurity. Risk factors associated with speed of retina...

journal_title：BioMed research international

authors： Solans Pérez de Larraya AM,Ortega Molina JM,Uberos Fernández J,González Ramírez AR,García Serrano JL

更新日期：2019-04-24 00:00:00

abstract：:Alzheimer's disease (AD) and multiple sclerosis are major neurodegenerative diseases, which are characterized by the accumulation of abnormal pathogenic proteins due to oxidative stress, mitochondrial dysfunction, impaired autophagy, and pathogens, leading to neurodegeneration and behavioral deficits. Herein, we revie...

journal_title：BioMed research international

authors： Tandon A,Singh SJ,Chaturvedi RK

更新日期：2018-07-12 00:00:00

abstract：:Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the lev...

journal_title：BioMed research international

authors： Zanzani SA,Gazzonis AL,Scarpa P,Berrilli F,Manfredi MT

更新日期：2014-01-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Inducible nitric oxide synthase (iNOS) and p53 are associated with a variety of human cancers, but their expression and interaction in OSCC have not been fully explored. In this study, we investigated the expression of iNOS and p53 in OSCC ...

journal_title：BioMed research international

authors： Yang L,Wang Y,Guo L,Wang L,Chen W,Shi B

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To assess whether high-molecular-weight proteins excretion predicts outcome and therapy-responsiveness in patients with FSGS and nephrotic syndrome. RESEARCH DESIGN AND METHODS:Thirty-eight patients measured at biopsy fractional excretion of IgG (FEIgG) and urinary α2-macroglobulin/creatinine ratio ( α m/C)....

journal_title：BioMed research international

authors： Bazzi C,Rizza V,Casellato D,Stivali G,Rachele G,Napodano P,Gallieni M,D'Amico G

更新日期：2013-01-01 00:00:00

abstract：:We study the interaction of 3T3 Swiss albino mouse fibroblasts with polymeric nanoparticles (NPs) and investigate cellular behaviour in terms of viability/cytotoxicity, cell cycle, NPs uptake, MAP kinase (ERK1/2), and focal adhesion kinase (FAK) activation. After incubation of NPs with cell culture media, western blot...

journal_title：BioMed research international

authors： Rosso F,Marino G,Grimaldi A,Cafiero G,Chiellini E,Chiellini F,Barbarisi M,Barbarisi A

更新日期：2013-01-01 00:00:00

abstract：:Peroxisome proliferators-activated receptor (PPAR) gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63...

journal_title：BioMed research international

authors： Zhou T,Yan X,Wang G,Liu H,Gan X,Zhang T,Wang J,Li L

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate whether blood transfusions affect overall survival (OS) and progression-free survival (PFS) in newly diagnosed multiple myeloma (MM) patients without hematopoietic stem cell transplantation. A total of 181 patients were enrolled and divided into two groups: 68 patients in the tran...

journal_title：BioMed research international

authors： Fan L,Fu D,Zhang J,Huang H,Wang Q,Ye Y,Xie Q

更新日期：2017-01-01 00:00:00

abstract：Objective:This paper included a retrospective review of the effect of tranexamic acid (TXA) combined with pressure bandaging on hemostasis of patients who received a unilateral total knee arthroplasty (TKA) from 2017 to 2019. Methods:A total of 197 patients undergoing TKA were chosen to be classified into 2 groups, th...

journal_title：BioMed research international

authors： Li GH,Ding LM,Sun L,Wang F

更新日期：2020-11-02 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：:Natural products are valuable sources for drug discovery because they have a wide variety of useful chemical components and biological properties. A quick reevaluation of the potential therapeutic properties of established natural products was made possible by the recent development of the methodology and improvement ...

journal_title：BioMed research international

authors： Jeon YJ,Shin JI,Lee S,Lee YG,Kim JB,Kwon HC,Kim SH,Kim I,Lee K,Han YS

更新日期：2018-08-01 00:00:00

abstract：:Lipases are water-soluble enzymes that act on insoluble substrates and catalyze the hydrolysis of long-chain triglycerides. Lipases play a vital role in the food, detergent, chemical, and pharmaceutical industries. In the past, fungal lipases gained significant attention in the industries due to their substrate specif...

journal_title：BioMed research international

authors： Gopinath SC,Anbu P,Lakshmipriya T,Hilda A

更新日期：2013-01-01 00:00:00

abstract：:Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English...

journal_title：BioMed research international

authors： Abate M,Schiavone C,Salini V

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study is to investigate the stress distributions of different restoration options for class II mesio-occluso-distal (MOD) cavities. A class II MOD cavity with proximal box gingival floor 1 mm below cementoenamel junction was designed in a mandibular first molar tooth model. 3D finite-element analysis (...

journal_title：BioMed research international

authors： Alp Ş,Gulec Alagoz L,Ulusoy N

更新日期：2020-12-15 00:00:00

abstract：:In previous studies, we have demonstrated the function of uc.167 in the heart development. DNA methylation plays a crucial role in regulating the expression of developmental genes during embryonic development. In this study, the methylomic landscape was investigated in order to identify the DNA methylation alterations...

journal_title：BioMed research international

authors： Yin A,Feng M,Cheng Z,Zhang Q,Li H,Xu J,Zhang H,Li Y,Qian L

更新日期：2018-05-30 00:00:00

abstract：:There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma sam...

journal_title：BioMed research international

authors： Zhou W,Zhang S,Li HB,Cai Z,Tang S,Chen LX,Lang JY,Chen Z,Chen XL

更新日期：2020-09-02 00:00:00

abstract：:We applied a metabolomic approach to monitor the modifications occurring in goat vitreous humor (VH) metabolite composition at different times (0, 6, 12, 18, and 24 hours) after death. The (1)H-NMR analysis of the VH samples was performed for the simultaneous determination of several metabolites (i.e., the metabolite ...

journal_title：BioMed research international

authors： Rosa MF,Scano P,Noto A,Nioi M,Sanna R,Paribello F,De-Giorgio F,Locci E,d'Aloja E

更新日期：2015-01-01 00:00:00