Angelica gigas Nakai Has Synergetic Effects on Doxorubicin-Induced Apoptosis.

abstract：:This work aimed to explore the cardiovascular effects induced by freeze-dried juice from Syzygium jambolanum (Lam.) DC fruits (JSJ). JSJ presented high polyphenol content and steroids. HPLC analysis revealed that 2,5-dihydroxybenzoic and caffeic acid were present in higher amounts in the JSJ extract. In rat, JSJ induc...

journal_title：BioMed research international

authors： Assis KS,Araújo IGA,de Azevedo FLAA,Maciel PMP,Machado Calzerra NT,da Silva TAF,Assis VL,de Vasconcelos AP,Santos CAG,Meireles BRLA,Cordeiro AMTM,Araújo DAM,Ribeiro TP,Medeiros IA

更新日期：2018-10-08 00:00:00

abstract：OBJECTIVE:Lipoprotein-associated phospholipase A2 (Lp-PLA2), a marker of vascular inflammation, is associated with cardiovascular disease. This prospective study of an inception cohort aimed to investigate whether the level of Lp-PLA2 is associated with subclinical atherosclerosis in patients with rheumatoid arthritis ...

journal_title：BioMed research international

authors： Södergren A,Karp K,Bengtsson C,Möller B,Rantapää-Dahlqvist S,Wållberg-Jonsson S

更新日期：2015-01-01 00:00:00

abstract：:In patients with sepsis and septic shock, the hemodynamic management in both early and later phases of these "organ dysfunction syndromes" is a key therapeutic component. It needs, however, to be differentiated between "early goal-directed therapy" (EGDT) as proposed for the first 6 hours of emergency department treat...

journal_title：BioMed research international

authors： Saugel B,Huber W,Nierhaus A,Kluge S,Reuter DA,Wagner JY

更新日期：2016-01-01 00:00:00

abstract：:A set of optical models associated with blood cells are introduced in this paper. All of these models are made up of different parts possessing symmetries. The wrapped phase images as well as the unwrapped ones from two orthogonal directions related to some of these models are obtained by simulation technique. Because...

journal_title：BioMed research international

authors： Ji Y,Liang M,Hua T,Xu Y,Xin Z,Wang Y

更新日期：2015-01-01 00:00:00

abstract：Background:Thyroid cancer is the most common endocrine malignancy, with a recent global increase of 20% in age-related incidence. Ultrasonography and ultrasonography-guided fine-needle aspiration biopsy (FNAB) are the most widely used diagnostic tests for thyroid nodules; however, it is estimated that up to 25% of thyr...

journal_title：BioMed research international

authors： Nan BY,Xiong GF,Zhao ZR,Gu X,Huang XS

更新日期：2021-01-12 00:00:00

abstract：Materials and Methods:Various aqueous extracts were prepared from this plant and preadministered per os to albino mice 3 h before APAP administration, once daily for one week. Animals from the normal group were given only distilled water while those from negative control received only APAP 250 mg/kg. After treatment, m...

journal_title：BioMed research international

authors： Galani BRT,Owona BA,Chuisseu DPD,Machewere E,Ngantchouko CBN,Moundipa PF

更新日期：2020-08-31 00:00:00

abstract：:Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Here we show that, while HA evolution is much more complex than NA evolution, it still shows abrupt punctuation changes linked to punctuation changes of NA. HA exhibits proteinquakes, which resemble earthqua...

journal_title：BioMed research international

authors： Phillips JC

更新日期：2015-01-01 00:00:00

abstract：:Recent work in preservation of female fertility as well as new information on the nature of spermatogonial stem cells has prompted an investigation into the possibility of an effective clinical-grade procedure for the cryopreservation of testicular cells and/or tissue. Clinical-grade reagents, validated equipment, and...

journal_title：BioMed research international

authors： Pacchiarotti J,Ramos T,Howerton K,Greilach S,Zaragoza K,Olmstead M,Izadyar F

更新日期：2013-01-01 00:00:00

abstract：:The principle mechanism of protection of stem cells is through the expression of ATP-binding cassette (ABC) transporters. These transporters serve as the guardians of the stem cell population in the body. Unfortunately these very same ABC efflux pumps afford protection to cancer stem cells in tumors, shielding them fr...

journal_title：BioMed research international

authors： Moitra K

更新日期：2015-01-01 00:00:00

abstract：:Since 2001 the Istituto Superiore di Sanità established a quality assurance programme for molecular genetic testing that covers four pathologies: Cystic Fibrosis (CF), Beta Thalassemia (BT), Fragile X Syndrome (FX), and Familial Adenomatous Polyposis Coli (APC). Since 2009 this activity is an institutional activity an...

journal_title：BioMed research international

authors： Censi F,Tosto F,Floridia G,Marra M,Salvatore M,Baffico AM,Grasso M,Melis MA,Pelo E,Radice P,Ravani A,Rosatelli C,Resta N,Russo S,Seia M,Varesco L,Falbo V,Taruscio D

更新日期：2013-01-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) has a significant clinical relevance of being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available targeted agents. Increased aggressiveness of this tumor, as well as resistance to standard drug therapies, may be as...

journal_title：BioMed research international

authors： Collina F,Di Bonito M,Li Bergolis V,De Laurentiis M,Vitagliano C,Cerrone M,Nuzzo F,Cantile M,Botti G

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

journal_title：BioMed research international

authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

更新日期：2019-03-19 00:00:00

abstract：Background:Doublecortin-like kinase 1 (DCLK1) has been universally identified as a cancer stem cell (CSC) marker and is found to be overexpressed in many types of cancers including breast cancer. However, there is little data regarding the functional role of DCLK1 in breast cancer metastasis. In the present study, we s...

journal_title：BioMed research international

authors： Liu H,Wen T,Zhou Y,Fan X,Du T,Gao T,Li L,Liu J,Yang L,Yao J,Ge Y,An G

更新日期：2019-05-15 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：PURPOSE:To assess glutamine/glutamate (Glx) and lactate (Lac) metabolism using proton magnetic resonance spectroscopic imaging (1H-MRS) in order to differentiate between adrenal gland nodules and masses (adenomas, pheochromocytomas, carcinomas, and metastases). MATERIALS AND METHODS:Institutional review board approval...

journal_title：BioMed research international

authors： Goldman SM,Nunes TF,Melo HJ,Dalavia C,Szejnfeld D,Kater C,Andreoni C,Szejnfeld J,Ajzen SA

更新日期：2013-01-01 00:00:00

abstract：:Long-term chronic intermittent exposure to altitude hypoxia is a labor phenomenon requiring further research. Using a rat model, we examined whether this type of exposure differed from chronic exposure in terms of pulmonary artery remodeling and other features. Rats were subjected to chronic hypoxia (CH, n = 9) and lo...

journal_title：BioMed research international

authors： Brito J,Siques P,Arribas SM,López de Pablo AL,González MC,Naveas N,Arriaza K,Flores K,León-Velarde F,Pulido R,Ordenes S,López MR

更新日期：2015-01-01 00:00:00

abstract：:The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5'-hydroxy auraptene (5'-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stimulator for osteobla...

journal_title：BioMed research international

authors： Abdallah BM,Ali EM,Elsawy H,Badr GM,Abdel-Moneim AM,Alzahrani AM

更新日期：2019-12-28 00:00:00

abstract：:The characteristics of FDG uptake in the physiologic and malignant nasopharynx were investigated in the paper which was correlated with either pathologic findings or clinical follow-up. Three patients had pathologically established nasopharyngeal malignancy. In the 3 nasopharyngeal malignancies, 2 had diffusely and ex...

journal_title：BioMed research international

authors： Ma C,Zou R,Huo Y,Chen S,Wang S,Wu S,Ye Z,Wu Z,Fang F,Wang H

更新日期：2015-01-01 00:00:00

abstract：Objective:To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods:We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combin...

journal_title：BioMed research international

authors： Xu Z,Wu Z,Zhang J,Zhou R,Wu J,Yu B

更新日期：2020-08-12 00:00:00

abstract：:Small bowel obstructions (SBOs) caused by adhesions are a common, often life-threatening postsurgical complication with few treatment options available for patients. This study examines the efficacy of a manual physical therapy treatment regimen on the pain and quality of life of subjects with a history of bowel obstr...

journal_title：BioMed research international

authors： Rice AD,Patterson K,Reed ED,Wurn BF,Klingenberg B,King CR 3rd,Wurn LJ

更新日期：2016-01-01 00:00:00

abstract：:Increased sugar consumption, especially fructose, is strongly related to the development of type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long term effects of fructose supplementation on Wistar rats. Three-week-old male rats were randomly divided into 2 groups: control (C; n = 14)...

journal_title：BioMed research international

authors： Dupas J,Feray A,Goanvec C,Guernec A,Samson N,Bougaran P,Guerrero F,Mansourati J

更新日期：2017-01-01 00:00:00

abstract：:Nutrient overload leads to impaired muscle oxidative capacity and insulin sensitivity. However, comparative analyses of the effects of dietary manipulation on skeletal muscles with different fiber composition are lacking. This study aimed to investigate the selective adaptations in the soleus and tibialis anterior mus...

journal_title：BioMed research international

authors： Collino M,Mastrocola R,Nigro D,Chiazza F,Aragno M,D'Antona G,Minetto MA

更新日期：2014-01-01 00:00:00

abstract：:A dentin-cement-prosthesis complex restored with either all-porcelain, cured resin-composite, or cast base metal alloy and cemented with either of the different resin cements was trimmed into a mini-dumbbell shape for tensile testing. The fractured surfaces and characterization of the dentin-cement interface of bonded...

journal_title：BioMed research international

authors： Piemjai M,Nakabayashi N

更新日期：2015-01-01 00:00:00

abstract：:Impact of bone mesenchymal stem cell (BMSC) transfusion on chronic smoking-induced lung inflammation is poorly understood. In this study, a rat model of smoking-related lung injury was induced and the rats were treated with vehicle or BMSCs for two weeks. Different subsets of CD4+ T cells, cytokines, and anti-elastin ...

journal_title：BioMed research international

authors： Li X,Wang J,Cao J,Ma L,Xu J

更新日期：2015-01-01 00:00:00

abstract：:Acetabular fractures involving predominantly the anterior column associated with a disruption of the quadrilateral surface can be treated with instrumentation implementing the stabilization of the quadrilateral surface. The recently introduced suprapectineal quadrilateral buttress plate is specifically designed to pre...

journal_title：BioMed research international

authors： Egli RJ,Keel MJB,Cullmann JL,Bastian JD

更新日期：2017-01-01 00:00:00

abstract：:Peritoneal dialysis (PD) is associated with structural and functional alterations of the peritoneal membrane, consisting of fibrosis, angiogenesis, and loss of ultrafiltration capacity. Vitamin D receptor activation (VDRA) plays an important role in mineral metabolism and inflammation, but also antiangiogenic and anti...

journal_title：BioMed research international

authors： Stavenuiter AW,Farhat K,Vila Cuenca M,Schilte MN,Keuning ED,Paauw NJ,ter Wee PM,Beelen RH,Vervloet MG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Assessing the role of breast MRI compared to galactography in patients with unilateral bloody or serous-bloody nipple discharge. MATERIALS AND METHODS:Retrospective study including 53 unilateral discharge patients who performed galactography and MRI. We evaluated the capability of both techniques in identifyin...

journal_title：BioMed research international

authors： Manganaro L,D'Ambrosio I,Gigli S,Di Pastena F,Giraldi G,Tardioli S,Framarino M,Porfiri LM,Ballesio L

更新日期：2015-01-01 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：:Studies have found that biotin favors glucose and lipid metabolism, and medications containing biotin have been developed. Despite the use of biotin as a pharmacological agent, few studies have addressed toxicity aspects including the possible interaction with cytochrome P450 enzyme family. This study analyzed the eff...

journal_title：BioMed research international

authors： Ronquillo-Sánchez MD,Camacho-Carranza R,Fernandez-Mejia C,Hernández-Ojeda S,Elinos-Baez M,Espinosa-Aguirre JJ

更新日期：2013-01-01 00:00:00