Abstract:
:Patients aged from 40 to 60 with displaced fractures of the femoral neck (Garden III or IV) who received fixation with three cannulated screws from January 2005 to December 2012 were evaluated retrospectively for the development of nonunion. Plasma HbA1C, a marker for long-term plasma glucose level, anti-T2DM medication, and other potential risk factors were recorded for the purpose of this study. There were no differences between the union and nonunion groups with respect to age, gender, Garden classification, Pauwel's angle, reduction quality, and T2DM presence. There were significant differences in reduction quality and preoperative plasma HbA1C level between patients with and those without union. The odds ratio (OR) for fracture nonunion was 2.659 (95% confidence interval [CI], 1.530-4.620) in subjects with anatomical reduction compared with those without anatomical reduction, 4.797 (95% CI, 1.371-16.778), in subjects with poor blood glucose control (HbA1C > 10%). The metformin usage showed a preventive effect on nonunion development (OR: 0.193 and CI: 0.060-0.616). The nonunion rate of metformin group (6.7%, 6/89) was even much lower than that of patients without T2DM (17.4%, 80/460).
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Zhu XZ,Zheng XYdoi
10.1155/2016/5682541subject
Has Abstractpub_date
2016-01-01 00:00:00pages
5682541eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章abstract:INTRODUCTION:Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported in SAH, their origin remains unclear. The aim of this study was to report the detection of ES during routine TCD monitoring in patients with aneurysmal SAH. METHODS:...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/153714
更新日期:2015-01-01 00:00:00
abstract:Purpose:To explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Methods:12 female freshmen with depression were filtered by the Beck Depression I...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5246350
更新日期:2020-02-27 00:00:00
abstract::SARS-CoV-2 pandemic and COVID-19 diffusion have recently become an international public health emergency. Cancer patients, as a frail population, are particularly exposed to the risk related to infections. The clinical decision-making process and the organizational workflow of radiotherapy department should be revised...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/4892382
更新日期:2020-05-26 00:00:00
abstract::Endothelial-to-mesenchymal transition (EndMT) emerges as an important source of fibroblasts. MicroRNA let-7 exhibits anti-EndMT effects and fibroblast growth factor (FGF) receptor has been shown to be an important in microRNA let-7 expression. The endogenous antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline (...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/696475
更新日期:2014-01-01 00:00:00
abstract::Adipose-derived stem cells (ADSCs) are an abundant cell source and provide an easy way to harvest mesenchymal stem cells, which are the focus of considerable attention in regenerative medicine. Electric fields (EF) play roles in many biological events and have been reported to promote cell proliferation, migration, an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7134719
更新日期:2020-11-06 00:00:00
abstract::The achievement of successful biostimulation of active microbiomes for the cleanup of a polluted site is strictly dependent on the knowledge of the key microorganisms equipped with the relevant catabolic genes responsible for the degradation process. In this work, we present the characterization of the bacterial commu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/242856
更新日期:2015-01-01 00:00:00
abstract:Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8398156
更新日期:2018-02-14 00:00:00
abstract::Ultrasonography has been widely employed to estimate the morphological changes of muscle during contraction. To further investigate the motion pattern of quadriceps during isometric knee extensions, we studied the relative motion pattern between femur and quadriceps under ultrasonography. An interesting observation is...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6385315
更新日期:2018-03-18 00:00:00
abstract::Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9436280
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Aortic diameters, aortic distensibility, microalbuminuria, coronary artery disease which are all together related to vascular aging are investigated in this paper. METHODS:Eighty consecutive nondiabetic patients undergoing elective coronary angiography were enrolled into the study. Systolic and diastolic ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/857628
更新日期:2015-01-01 00:00:00
abstract::Preeclampsia (PE) is a unique complication of pregnancy, the pathogenesis of which has been generally accepted to be associated with the dysfunctions of extravillous trophoblast (EVT) including proliferation, apoptosis, and migration and invasion. Decorin (DCN) has been proved to be a decidua-derived TGF-binding prote...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/201629
更新日期:2015-01-01 00:00:00
abstract::Perinatal infections have a negative impact on brain development. However, the underlying mechanisms leading to neurological impairment are not completely understood and reliable models of inflammation are urgently needed. Using phorbol-myristate-acetate as an activator of inflammation, we investigated the effect on t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/318306
更新日期:2015-01-01 00:00:00
abstract::The aim of the present study was to extract and characterize bioactive components from separate body organs of Holothuria leucospilota. Preliminary qualitative assessment of the crude extracts was positive for phenols, terpenoids, carbohydrates, flavonoids, saponins, glycosides, cardiac glycosides, steroids, phlobatan...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2640684
更新日期:2019-04-15 00:00:00
abstract::Myocardial ischemia-reperfusion (I/R) injury is experienced by individuals suffering from cardiovascular diseases such as coronary heart diseases and subsequently undergoing reperfusion treatments in order to manage the conditions. The occlusion of blood flow to the tissue, termed ischemia, can be especially detriment...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/864946
更新日期:2015-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2020/4671349.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2020/7638969
更新日期:2020-06-30 00:00:00
abstract::Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the lev...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/696508
更新日期:2014-01-01 00:00:00
abstract::Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 (EZR-AS1) is associated with the progression of coronary heart disease (CHD) remains unclear. Accordingly, the aim of th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6840234
更新日期:2020-05-22 00:00:00
abstract::Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due to a reduced capacity to vasoconstrict the venous and arterial vessels below the level of the lesion. Exercise training was found to enhance circulating catecholamines and to improve cardiac preload and venous ton...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/893468
更新日期:2014-01-01 00:00:00
abstract::The influence of biomimetic calcium phosphate coating on osteoblasts behavior in vitro is not well established yet. In this study, we investigated the behavior of osteoblastic rat osteosarcoma 17/2.8 cells (ROS17/2.8) on two groups of biomaterial surfaces: alkaline-treated titanium surface (ATT) and biomimetic calcium...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/832790
更新日期:2013-01-01 00:00:00
abstract::The release of ATP from the urothelium in response to stretch during filling demonstrates the importance of the purinergic system for the physiological functioning of the bladder. This study examined the effect of P2 receptor agonists on ATP release from two urothelial cell lines (RT4 and UROtsa cells). Hypotonic Kreb...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/830374
更新日期:2014-01-01 00:00:00
abstract:Purpose:Coconut water has long been touted for its medicinal qualities including natural hydration. We sought to determine whether its consumption would induce changes to urinary lithogenic factors beyond changes in urine volume. Materials and Methods:After Institutional Review Board approval, volunteers with no prior...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3061742
更新日期:2018-11-01 00:00:00
abstract:Background:The Oxford Happiness Inventory (OHI) is a self-report tool to measure happiness. A brief review of previous studies on OHI showed the lack of evaluation of OHI fairness/equivalence in measuring happiness among identified groups. Methods:To examine the psychometric properties and measurement invariance of th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8906209
更新日期:2020-06-21 00:00:00
abstract::Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/635732
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/459203
更新日期:2014-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2018/2109865.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2019/6212386
更新日期:2019-12-13 00:00:00
abstract::Three novel low molecular weight polysaccharides (RLP-1a, RLP-2a, and RLP-3a) with 9004, 8761, and 7571 Da were first obtained by purifying the crude polysaccharides from the fruits of a traditional Chinese medicinal herb Rosae Laevigatae. The conditions for polysaccharides from the R. Laevigatae fruit (RLP) extractio...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2043785
更新日期:2020-10-22 00:00:00
abstract::Chronic Obstructive Pulmonary Disease (COPD) is defined as a disease characterized by persistent, progressive airflow limitation. Recent studies have underlined that COPD is correlated to many systemic manifestations, probably due to an underlying pattern of systemic inflammation. In COPD fractional exhaled Nitric Oxi...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/271918
更新日期:2014-01-01 00:00:00
abstract::Despite remarkable therapeutic advances have been made in the last few decades, non-small cell lung cancer (NSCLC) is still one of the leading causes of death worldwide. Brain metastases are a common complication of a wide range of human malignancies and in particular NSCLC. Brain-derived neurotrophic factor (BDNF), b...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4193541
更新日期:2020-11-17 00:00:00
abstract::Myofascial pain syndrome is characterized by pain and a limited range of joint motion caused by muscle contracture related to motor-end-plate dysfunction and the presence of myofascial trigger points (MTrPs). It is the most frequent cause of musculoskeletal pain, with a worldwide prevalence varying between 13.7% and 4...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9240581
更新日期:2020-01-22 00:00:00
abstract::This study was designed to explore the effect of basic fibroblast growth factor (bFGF) on radiation-induced endothelial dysfunction and histological changes in the urinary bladder. bFGF was administrated to human umbilical vein cells (HUVEC) or urinary bladder immediately after radiation. Reduced expression of thrombo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/967680
更新日期:2015-01-01 00:00:00