Enhanced Production of Polymyxin E in Paenibacillus polymyxa by Replacement of Glucose by Starch.

abstract：:Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

journal_title：BioMed research international

authors： Xu C,Zhang H

更新日期：2015-01-01 00:00:00

abstract：Background:Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by sacroiliitis and spinal rigidity of the axial joints. The role of oxidative stress and increased proinflammatory cytokines is well documented in AS pathogenesis. Punicalagin (2,3-hexahydroxydiphenoyl-gallagyl-D-glucose), an ellagi...

journal_title：BioMed research international

authors： Feng X,Yang Q,Wang C,Tong W,Xu W

更新日期：2020-09-23 00:00:00

abstract：:Natural products are valuable sources for drug discovery because they have a wide variety of useful chemical components and biological properties. A quick reevaluation of the potential therapeutic properties of established natural products was made possible by the recent development of the methodology and improvement ...

journal_title：BioMed research international

authors： Jeon YJ,Shin JI,Lee S,Lee YG,Kim JB,Kwon HC,Kim SH,Kim I,Lee K,Han YS

更新日期：2018-08-01 00:00:00

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00

abstract：:Adiponectin (APN) is an adipokine secreted from adipose tissue and exhibits biological functions such as microcirculation-regulating, hearing-protective, and antiapoptotic. However, the effect of APN on the apoptosis of spiral arterial smooth muscle cells (SMCs) under hypoxic conditions in vitro is not clear. We used ...

journal_title：BioMed research international

authors： Xiao J,Zhang Y,Zhang W,Zhang L,Li L,Si J,Li X,Ma K

更新日期：2020-10-10 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：:A comparison of the superior and inferior rectus muscles was performed to determine whether they have similar structures and innervation attributable to their participation in the same type of, although antagonistic, eye movements. The study was conducted on 70 cadaveric hemiheads, and the anatomical variations in the...

journal_title：BioMed research international

authors： Haładaj R,Polguj M,Tubbs RS

更新日期：2020-04-30 00:00:00

abstract：:Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

journal_title：BioMed research international

authors： Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

更新日期：2020-01-23 00:00:00

abstract：PURPOSE:To investigate the correlation of outer retinal layers (ORL) thickness and visual acuity (VA) in patients with diabetic macular edema (DME). METHODS:Consecutive DME patients seen at the Retina Clinic of The University of Hong Kong were recruited for OCT assessment. The ORL thickness was defined as the distance...

journal_title：BioMed research international

authors： Wong RL,Lee JW,Yau GS,Wong IY

更新日期：2015-01-01 00:00:00

abstract：:Objectives. The aim of the study is to detect the prevalence and the characteristics of infraorbital canal and Haller's cells on panoramic radiography of edentulous patients. Methods. The study group comprised 291 panoramic radiographs of edentulous patients. Radiographs were interpreted for the visibility and charact...

journal_title：BioMed research international

authors： Yesilova E,Bayrakdar IS

更新日期：2018-07-08 00:00:00

abstract：:Due to alarming increase in population and rapid industrialization, drinking water quality is being deteriorated day by day in Pakistan. This review sums up the outcomes of various research studies conducted for drinking water quality status of different areas of Pakistan by taking into account the physicochemical pro...

journal_title：BioMed research international

authors： Daud MK,Nafees M,Ali S,Rizwan M,Bajwa RA,Shakoor MB,Arshad MU,Chatha SAS,Deeba F,Murad W,Malook I,Zhu SJ

更新日期：2017-01-01 00:00:00

abstract：:Bayesian analysis was used to estimate the pig's and herd's true prevalence of enteropathogenic Yersinia in serum samples collected from Finnish pig farms. The sensitivity and specificity of the diagnostic test were also estimated for the commercially available ELISA which is used for antibody detection against entero...

journal_title：BioMed research international

authors： Vilar MJ,Ranta J,Virtanen S,Korkeala H

更新日期：2015-01-01 00:00:00

abstract：:For more than 30 years, heart transplantation has been a successful therapy for patients with terminal heart failure. Mechanical circulatory support (MCS) was developed as a therapy for end-stage heart failure at a time when cardiac transplantation was not yet a useful treatment modality. With the more successful outc...

journal_title：BioMed research international

authors： Anand J,Singh SK,Antoun DG,Cohn WE,Frazier OH,Mallidi HR

更新日期：2015-01-01 00:00:00

abstract：Background:Open laminectomy has been regarded as the standard surgical procedure for lumbar lateral recess stenosis during the last decades. Although percutaneous endoscopic lumbar decompression has led to successful results comparable with open decompression, its application in LSS with is still challenging and techni...

journal_title：BioMed research international

authors： Tang S,Jin S,Liao X,Huang K,Luo J,Zhu T

更新日期：2018-11-26 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC) K88 is a zoonotic pathogen. Previous studies have shown that lactic acid bacteria (LAB) have great potential in promoting health and resisting pathogenic infections; however, relatively little research has been done on the Pediococcus genus of LAB. This study is aimed at explori...

journal_title：BioMed research international

authors： Tan K,Deng D,Ma X,Cui Y,Tian Z

更新日期：2020-03-30 00:00:00

abstract：:We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock ...

journal_title：BioMed research international

authors： Smith JH,Cui M,Zhang DY,Beals TP,Ye F

更新日期：2014-01-01 00:00:00

abstract：:Besides the pinpointing of individual disease-related genes, associating protein complexes to human inherited diseases is also of great importance, because a biological function usually arises from the cooperative behaviour of multiple proteins in a protein complex. Moreover, knowledge about disease-related protein co...

journal_title：BioMed research international

authors： Jacquemin T,Jiang R

更新日期：2013-01-01 00:00:00

abstract：:The endoscopic and histopathological findings detected in Sparus aurata experimentally infected with third-stage Anisakis larvae without intermediate host are evaluated and discussed. In six fish, live nematode larvae were introduced by gastroscopy into the stomach. The first observation by endoscope, 15 days after ch...

journal_title：BioMed research international

authors： Marino F,Lanteri G,Passantino A,De Stefano C,Costa A,Gaglio G,Macrì F

更新日期：2013-01-01 00:00:00

abstract：:This work evaluated the physicochemical properties and antioxidant activity of spray dried extracts (SDE) from Psidium guajava L. leaves. Different drying carriers, namely, maltodextrin, colloidal silicon dioxide, Arabic gum, and β -cyclodextrin at concentrations of 40 and 80% relative to solids content, were added to...

journal_title：BioMed research international

authors： Fernandes MR,Azzolini AE,Martinez ML,Souza CR,Lucisano-Valim YM,Oliveira WP

更新日期：2014-01-01 00:00:00

abstract：:Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...

journal_title：BioMed research international

authors： Caimmi M,Guanziroli E,Malosio M,Pedrocchi N,Vicentini F,Molinari Tosatti L,Molteni F

更新日期：2015-01-01 00:00:00

abstract：:Previous studies indicated that intracerebroventricular administration of nerve growth factor (NGF) leads to massive Schwann cell hyperplasia surrounding the medulla oblongata and spinal cord. This study was designed to characterize the proliferation of peripheral glial cells, that is, Schwann and satellite cells, in ...

journal_title：BioMed research international

authors： Schlachetzki JC,Pizzo DP,Morrissette DA,Winkler J

更新日期：2014-01-01 00:00:00

abstract：:Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...

journal_title：BioMed research international

authors： Tharmarajah L,Samarakoon SR,Ediriweera MK,Piyathilaka P,Tennekoon KH,Senathilake KS,Rajagopalan U,Galhena PB,Thabrew I

更新日期：2017-01-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer-related death worldwide, and the most common histologic subtype is lung adenocarcinoma (LUAD). Due to the significant mortality and morbidity rates among patients with LUAD, the identification of novel biomarkers to guide diagnosis, prognosis, and therapy is urgent. Guanosine...

journal_title：BioMed research international

authors： Zhang Z,Wang J,Mao J,Li F,Chen W,Wang W

更新日期：2020-10-19 00:00:00

abstract：PURPOSE:To investigate whether P. acnes could induce disc degeneration and Modic changes when inoculated into the discs of rabbits. METHOD:A wild-type strain of P. acnes isolated from a patient associated with Modic change and disc degeneration was inoculated into the intervertebral discs of rabbits. Meanwhile, S. aur...

journal_title：BioMed research international

authors： Chen Z,Zheng Y,Yuan Y,Jiao Y,Xiao J,Zhou Z,Cao P

更新日期：2016-01-01 00:00:00

abstract：:Dysfunctions of chaperone-mediated autophagy (CMA), the main catabolic pathway for alpha-synuclein, have been linked to the pathogenesis of Parkinson's disease (PD). Since till now there is limited information on how PD-related toxins may affect CMA, in this study we explored the effect of mitochondrial complex I inhi...

journal_title：BioMed research international

authors： Sala G,Arosio A,Stefanoni G,Melchionda L,Riva C,Marinig D,Brighina L,Ferrarese C

更新日期：2013-01-01 00:00:00

abstract：Background:In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. Methods and Results:This pilot study (n=48) compared plasma levels of corin, neprilysin, ...

journal_title：BioMed research international

authors： Zaidi SS,Ward RD,Ramanathan K,Yu X,Gladysheva IP,Reed GL

更新日期：2018-07-26 00:00:00

abstract：:Background. The chronic recommendation of pediatric drugs could exhibit erosive and cariogenic problems. Objective. To evaluate the effects of different pediatric drugs on the color stability of various restorative materials. Methods. Five specimens (1 mm × 3 mm) were prepared and immersed in ten different pediatric d...

journal_title：BioMed research international

authors： Tüzüner T,Turgut S,Baygin O,Yilmaz N,Tuna EB,Ozen B

更新日期：2017-01-01 00:00:00

abstract：:Red blood cell distribution width (RDW) is a parameter reported in complete blood cell count tests, and has been reported as an inflammatory biomarker. Multiple myeloma (MM) is known to be associated with inflammatory microenvironments. However, the importance of RDW has been seldom studied in MM. For this study, 146 ...

journal_title：BioMed research international

authors： Lee H,Kong SY,Sohn JY,Shim H,Youn HS,Lee S,Kim HJ,Eom HS

更新日期：2014-01-01 00:00:00

abstract：:Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the chaperone protein HS...

journal_title：BioMed research international

authors： Zhang Y,Fu Y,Zhang F,Liu J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS:Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneou...

journal_title：BioMed research international

authors： Akashi M,Hashikawa K,Wanifuchi S,Kusumoto J,Shigeoka M,Furudoi S,Terashi H,Komori T

更新日期：2017-01-01 00:00:00