Current opportunities and challenges of magnetic resonance spectroscopy, positron emission tomography, and mass spectrometry imaging for mapping cancer metabolism in vivo.

abstract：:This study described a TaqMan based real-time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = -3.249...

journal_title：BioMed research international

authors： Chen R,Chen Q,Wu X,Che Y,Wang C,Wang L,Yan S,Zhou L

更新日期：2020-01-10 00:00:00

abstract：:Engineering three-dimensional (3D) vascularized constructs remains a challenge due to the inability to form rich microvessel networks. In this study we engineered a prevascularized 3D cell sheet construct for tissue regeneration using human bone marrow-derived mesenchymal stem cells (hMSCs) and human umbilical vein en...

journal_title：BioMed research international

authors： Ren L,Ma D,Liu B,Li J,Chen J,Yang D,Gao P

更新日期：2014-01-01 00:00:00

abstract：Background:Shedding of the endothelial glycocalyx layer (EGL) is known to occur during major surgery, but its degradation associated with minimally invasive video-assisted thoracoscopy (VATS) remains unclear. We investigated if serum biomarkers of EGL disruption were elevated during VATS lobectomy, and whether the urin...

journal_title：BioMed research international

authors： Wang J,Wu A,Wu Y

更新日期：2017-01-01 00:00:00

abstract：:Autoimmunity remains a complex physiologic deviation, enabled and perpetuated by a variety of interplayers and pathways. Simplistic approaches, targeting either isolated end-effectors of more centrally placed interactors of these mechanisms, are continuously tried in an effort to comprehend and halt cascades with pote...

journal_title：BioMed research international

authors： Pateinakis P,Pyrpasopoulou A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:Trace elements and vitamins play a vital role in human body to perform its function properly. Thalassemic patients are at risk of micronutrient deficiency. This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elemen...

journal_title：BioMed research international

authors： Sherief LM,Abd El-Salam SM,Kamal NM,El Safy O,Almalky MA,Azab SF,Morsy HM,Gharieb AF

更新日期：2014-01-01 00:00:00

abstract：:Cardiotonic drugs mainly include digitalis, catecholamines, phosphodiesterase inhibitors, and calcium sensitizers, which have been successively discovered and applied in clinical practice. However, there are only a few new drugs available in this field, and the selection is very limited. Digitalis, catecholamines, and...

journal_title：BioMed research international

authors： Pan J,Yang YM,Zhu JY,Lu YQ

更新日期：2019-09-19 00:00:00

abstract：:This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...

journal_title：BioMed research international

authors： Moss J,Tew GA,Copeland RJ,Stout M,Billings CG,Saxton JM,Winter EM,Bianchi SM

更新日期：2014-01-01 00:00:00

abstract：:Coronary heart disease (CHD) has become one of the leading causes of death and functional impairment in the world. Hyperglycemia is associated with an increased risk of cardiovascular disease. It was speculated that miRNAs in peripheral blood were a primary parameter in discriminating CHD. The biological characteristi...

journal_title：BioMed research international

authors： Jiang Y,Liu N,Xue B,Hou J,Lin C,Ren J,Liu J

更新日期：2017-01-01 00:00:00

abstract：:The development of multitargeting drugs is an emerging trend in cancer research. To promote further development and clinical application of multitargeting drugs, this research was performed. MTT assay and flow cytometry of Annexin V/propidium iodide staining were used to confirm the proapoptotic efficacy of a novel co...

journal_title：BioMed research international

authors： Zheng H,Liang G,Chen Y,Lin S,Liu W,Fang Y

更新日期：2017-01-01 00:00:00

abstract：:Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved in the initiation ...

journal_title：BioMed research international

authors： Chen TH,Liu SW,Chen MR,Cho KH,Chen TY,Chu PH,Kao YY,Hsu CH,Lin KM

更新日期：2015-01-01 00:00:00

abstract：Introduction:Retinol Binding Protein 4 (RBP4) is mainly excreted by the kidney and plays a pivotal role in insulin resistance (IR). In our study, we evaluated the association between RBP4 and IR in hemodialysis subjects (HD). We also assessed how circulating RBP4 could be influenced by kidney transplant or different di...

journal_title：BioMed research international

authors： Grosjean F,Esposito P,Maccarrone R,Libetta C,Dal Canton A,Rampino T

更新日期：2017-01-01 00:00:00

abstract：:Giardia duodenalis is a small intestinal protozoan parasite of several terrestrial vertebrates. This work aims to assess the genotypic variability of Giardia duodenalis isolates from cattle, sheep and pigs in the Southeast of Brazil, by comparing the standard characterization between glutamate dehydrogenase (gdh) and ...

journal_title：BioMed research international

authors： Fava NM,Soares RM,Scalia LA,Kalapothakis E,Pena IF,Vieira CU,Faria ES,Cunha MJ,Couto TR,Cury MC

更新日期：2013-01-01 00:00:00

abstract：:Molecular epidemiology has revealed that Mycobacterium tuberculosis (Mtb), formerly regarded as highly conserved species, displays a considerable degree of genetic variability that can influence the outcome of the disease as well as the innate and adaptive immune response. Recent studies have demonstrated that Mtb fam...

journal_title：BioMed research international

authors： Schierloh P,Klepp L,Vazquez C,Rocha RV,Blanco FC,Balboa L,López B,Ritacco V,Bigi F,Sasiain Mdel C

更新日期：2014-01-01 00:00:00

abstract：Background:Anion gap (AG) has been proved to be associated with prognosis of many cardiovascular diseases. This study is aimed at exploring the association of AG with inhospital all-cause mortality and adverse clinical outcomes in coronary care unit (CCU) patients. Method:All data of this study was extracted from Medi...

journal_title：BioMed research international

authors： Sun T,Cai C,Shen H,Yang J,Guo Q,Zhang J,Zhang B,Ding Y,Zhou Y

更新日期：2020-08-27 00:00:00

abstract：:High-dose melphalan (200 mg/m(2)) as conditioning regimen followed by autologous stem cell transplantation (ASCT) rescue has been established as a standard treatment for patients with multiple myeloma (MM) younger than 65 years of age. However, the role of ASCT in elderly patients older than 65 years remains controver...

journal_title：BioMed research international

authors： Ozaki S,Shimizu K

更新日期：2014-01-01 00:00:00

abstract：Background and Aims:The value of hepatocyte regeneration in predicting the outcomes of hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) is not fully assessed. The present study was aimed at establishing a novel scoring system to predict patients' outcomes within 3 months by applying serological indicators ...

journal_title：BioMed research international

authors： Wang X,Sun M,Yang X,Gao L,Weng M,Yang D,Li H,Zhou X,Li J,Qin S,Zhou D,Wu X,Tang S,Zeng W

更新日期：2020-08-06 00:00:00

abstract：:This paper reports the results of an ethnobotanical survey on the use of medicinal plants by community healers "Hampiyachakkuna" in the San Lucas Parish, province of Loja, Ecuador. A particular ethnic group, the indigenous Saraguros, inhabits this region. This study reports 183 plant species used in 75 different curat...

journal_title：BioMed research international

authors： Andrade JM,Lucero Mosquera H,Armijos C

更新日期：2017-01-01 00:00:00

abstract：:Biolasol is a newly developed solution for storing the liver, pancreas, kidneys, and heart by simple hypothermia. It exhibits high efficacy in maintaining structural and functional integrity of the graft prior to its transplantation. The solution was modified by the addition of ascorbic acid (0.088g/l) and ascorbic ac...

journal_title：BioMed research international

authors： Ostróżka-Cieślik A,Dolińska B,Ryszka F

更新日期：2018-11-12 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...

journal_title：BioMed research international

authors： Zhang Y,Lin Y,Liu Q,Yuan X,Mao A,Liu Y,Li Q,Zheng J,Hu B,Yu F

更新日期：2018-01-16 00:00:00

abstract：:The aim of this study was to analyze periprocedural and mid-term effect of clopidogrel on platelet function using the VerifyNow P2Y12 point-of-care assay in patients undergoing TAVI. Platelet reactivity was measured at the beginning of the procedure after 300 mg clopidogrel bolus administration and during the follow-u...

journal_title：BioMed research international

authors： Tousek P,Kocka V,Sulzenko J,Bednar F,Linkova H,Widimsky P

更新日期：2013-01-01 00:00:00

abstract：Purpose:3D nonfluoroscopic mapping systems (NMSs) are generally used in the catheter ablation (CA) of complex ventricular and atrial arrhythmias. The aim of this study was to evaluate the efficacy, safety, and long-term effect of the extended, routine use of NMSs for CA. Methods:Our study involved 1028 patients who un...

journal_title：BioMed research international

authors： Marini M,Martin M,Ravanelli D,Del Greco M,Quintarelli S,Guarracini F,Coser A,Valentini A,Bonmassari R

更新日期：2019-03-10 00:00:00

abstract：Aims:We aimed to summarize available lines of evidence about intraoperative and postoperative donor outcomes following robotic-assisted laparoscopic donor nephrectomy (RALDN) as well as outcomes of graft and recipients. Methods:A systematic review of PubMed/Medline, ISI Web of Knowledge, and Scopus databases was perfo...

journal_title：BioMed research international

authors： Creta M,Calogero A,Sagnelli C,Peluso G,Incollingo P,Candida M,Minieri G,Longo N,Fusco F,Tammaro V,Dodaro CA,Mangiapia F,Carlomagno N

更新日期：2019-04-22 00:00:00

abstract：Methods:This prospective single-blinded clinical trial included 72 ASA I-II stage children aged 1-36 months with cCHD who were scheduled to undergo TTE under sedation. Children were assigned to group A (n = 37) with a previous history of cardiac surgery and group B (n = 35) with no history of cardiac surgery. Doses of ...

journal_title：BioMed research international

authors： Gu H,Song Y,Bai J

更新日期：2020-12-12 00:00:00

abstract：:Uraemia and long-term peritoneal dialysis (PD) can lead to fibrotic thickening of the peritoneal membrane, which may limit its dialytic function. Peritoneal fibrosis is associated with the appearance of myofibroblasts and expansion of extracellular matrix. The extent of contribution of resident peritoneal fibroblasts ...

journal_title：BioMed research international

authors： Witowski J,Kawka E,Rudolf A,Jörres A

更新日期：2015-01-01 00:00:00

abstract：:Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process. This process is under the control of local (e.g., growth factors ...

journal_title：BioMed research international

authors： Florencio-Silva R,Sasso GR,Sasso-Cerri E,Simões MJ,Cerri PS

更新日期：2015-01-01 00:00:00

abstract：:In renal cell carcinoma, chromophobe renal cell carcinoma (ChRCC) is a distinct subtype, whose clinical manifestations often lack specificity, and the molecular mechanisms of ChRCC tumorigenesis remain generally vague. The target of this study was to discover novel biomarkers involved in ChRCC by integrated bioinforma...

journal_title：BioMed research international

authors： Zhang W,Xu Y,Zhang J,Wu J

更新日期：2020-02-07 00:00:00

abstract：AIMS:Nausea and vomiting of pregnancy is the most common medical condition in pregnancy. There is an increasing trend to prescribe ondansetron although its safety for use in pregnancy has not been established. METHODS:Exposed pregnancies were all births in Western Australia, 2002-2005, where the mother was dispensed o...

journal_title：BioMed research international

authors： Colvin L,Gill AW,Slack-Smith L,Stanley FJ,Bower C

更新日期：2013-01-01 00:00:00

abstract：:Mental rotation task (MRT) incorporates elements of spatial abilities, important in many professions, with people of both genders involved. Importantly, these are the areas where spatial tasks might be performed for long time periods; thus adverse effects of mental fatigue are highly unwanted. Substantial variation of...

journal_title：BioMed research international

authors： Noreika D,Griškova-Bulanova I,Alaburda A,Baranauskas M,Grikšienė R

更新日期：2014-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：:Endometriosis is a chronic disease of women in the reproductive age, defined as endometrial cells growing outside of the uterine cavity and associated with relapses. Relapses are hypothesized to correlate with incomplete surgical excision or result from nonrandom implantation of new endometrial implants in adjacent pe...

journal_title：BioMed research international

authors： Renner SP,Strissel PL,Beckmann MW,Lermann J,Burghaus S,Hackl J,Fasching PA,Strick R

更新日期：2015-01-01 00:00:00