Analysis of Transcription Factor-Related Regulatory Networks Based on Bioinformatics Analysis and Validation in Hepatocellular Carcinoma.

abstract：:Despite the rapid progression of cancer pharmacotherapy, the high drug resistance of pancreatic ductal adenocarcinoma (PDA) makes it one of the most lethal malignancies. Therefore, there are high expectations associated with experimental therapies, such as electrochemotherapy (ECT). This technique involves the applica...

journal_title：BioMed research international

authors： Michel O,Kulbacka J,Saczko J,Mączyńska J,Błasiak P,Rossowska J,Rzechonek A

更新日期：2018-03-19 00:00:00

abstract：:Angiogenesis and lymphangiogenesis are important in the proliferation and survival of the malignant hematopoietic neoplasms, including non-Hodgkin's lymphomas (NHLs). Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) play an important role in the initiation of angiogenesis. Both VEGF ...

journal_title：BioMed research international

authors： Wróbel T,Mazur G,Dzietczenia J,Gębura K,Kuliczkowski K,Bogunia-Kubik K

更新日期：2013-01-01 00:00:00

abstract：:In the present study, we determined whether there is a delay in the eruption of permanent teeth (PT) among Filipino adolescents with stunting or thinness. Height, weight, and number of PT were recorded in 1554 Filipino 10- to 13-year-olds (711 boys; 843 girls). z-scores for height (HAZ) and body mass index (BMI) were ...

journal_title：BioMed research international

authors： Heinrich-Weltzien R,Zorn C,Monse B,Kromeyer-Hauschild K

更新日期：2013-01-01 00:00:00

abstract：:Introduction. The aim of this study was to examine the incidence and risk factors of catheterization-related CI in the contemporary era, using diffusion-weighted magnetic resonance imaging. Methods. We retrospectively analyzed consecutive 84 patients who underwent MRI (magnetic resonance imaging) after 2.81 ± 2.4 days...

journal_title：BioMed research international

authors： Morita Y,Kato T,Okano M,Suu K,Kimura M,Minamino-Muta E,Nakane E,Izumi T,Miyamoto S,Haruna T,Ueyama K,Inoko M

更新日期：2016-01-01 00:00:00

abstract：:Purpose. We aimed to study long-term outcome after pulmonary vein isolation (PVI) guided by remote magnetic navigation (RMN) and provided comparative data to outcome after manual navigation (MAN). Methods. Three hundred thirty-six patients with symptomatic paroxysmal AF underwent PVI by irrigated point-by-point radiof...

journal_title：BioMed research international

authors： Kataria V,Berte B,Vandekerckhove Y,Tavernier R,Duytschaever M

更新日期：2017-01-01 00:00:00

abstract：:Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel indicator for diagnosis of diabetic kidney disease (DKD). The aim of this study was to investigate the possibility of serum HE4 as a novel biomarker for DKD in patients...

journal_title：BioMed research international

authors： Zhang M,Zhao B,Xie J,Liang Y,Yang Z

更新日期：2019-11-11 00:00:00

abstract：:The complete chloroplast genome of J. flava, an endangered medicinal plant in Saudi Arabia, was sequenced and compared with cp genome of three Acanthaceae species to characterize the cp genome, identify SSRs, and also detect variation among the cp genomes of the sampled Acanthaceae. NOVOPlasty was used to assemble the...

journal_title：BioMed research international

authors： Yaradua SS,Alzahrani DA,Albokhary EJ,Abba A,Bello A

更新日期：2019-08-06 00:00:00

abstract：:Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...

journal_title：BioMed research international

authors： Chen X,Wang Y,Wang P,Lian B,Li C,Wang J,Li X,Jiang W

更新日期：2015-01-01 00:00:00

abstract：:Diabetes-triggered apoptosis of Schwann cells (SC) contributes to the degradation of diabetic peripheral neuropathy (DNP). In recent years, mesenchymal stem cells (MSC) were applied to DPN repair and it was demonstrated that paracrine secretion played a key role in neuroprotection exerted by MSC. Erythropoietin (EPO) ...

journal_title：BioMed research international

authors： Zhang S,Shi B

更新日期：2017-01-01 00:00:00

abstract：:The neonatal immune system is still immature, which makes it more susceptible to the infectious agents. Neonatal immune activation is associated with increased permeability of the blood-brain barrier, causing an inflammatory cascade in the CNS and altering behavioral and neurochemical parameters. One of the hypotheses...

journal_title：BioMed research international

authors： Dias P,Freiberger V,Ventura L,Bragagnolo D,Dutra ML,Horewicz VV,Comim CM

更新日期：2019-08-05 00:00:00

abstract：:Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamella...

journal_title：BioMed research international

authors： Liu Y,Ji M,Wong MK,Joo KI,Wang P

更新日期：2013-01-01 00:00:00

abstract：:Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness amon...

journal_title：BioMed research international

authors： El Ghoul B,Daaboul Y,Korjian S,El Alam A,Mansour A,Hariri E,Samad S,Salameh P,Dahdah G,Blacher J,Safar ME,Aoun Bahous S

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h...

journal_title：BioMed research international

authors： Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MR

更新日期：2014-01-01 00:00:00

abstract：:This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

journal_title：BioMed research international

authors： Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

更新日期：2015-01-01 00:00:00

abstract：:The laser speckle contrast imaging (LSCI) is proved to be a reliable tool in flap monitoring in general surgery; however, it has not been evaluated in oral surgery yet. We applied the LSCI to compare the effect of a xenogeneic collagen matrix (Geistlich Mucograft®) to connective tissue grafts (CTG) on the microcircula...

journal_title：BioMed research international

authors： Molnár E,Molnár B,Lohinai Z,Tóth Z,Benyó Z,Hricisák L,Windisch P,Vág J

更新日期：2017-01-01 00:00:00

abstract：:Lipases are water-soluble enzymes that act on insoluble substrates and catalyze the hydrolysis of long-chain triglycerides. Lipases play a vital role in the food, detergent, chemical, and pharmaceutical industries. In the past, fungal lipases gained significant attention in the industries due to their substrate specif...

journal_title：BioMed research international

authors： Gopinath SC,Anbu P,Lakshmipriya T,Hilda A

更新日期：2013-01-01 00:00:00

abstract：Background:Clinical trials based on FGFR mutation or amplification as a druggable target of FGFR inhibitors have produced disappointing clinical outcomes. Therefore, the identification of predictive biomarkers for FGFR-targeted agents has remained a crucial issue. Methods:Expression profiles of FGFs and FGFRs in 8,111...

journal_title：BioMed research international

authors： Li Y,Wu L,Tao W,Wu D,Ma F,Li N

更新日期：2020-06-03 00:00:00

abstract：:Mortierella sp. has been known to produce polyunsaturated fatty acids (PUFAs) such as GLA and AA under normal growth medium conditions. Similarly, under the stress condition, this fungus produces EPA and DHA in their mycelial biomass. Among the 67 soil samples screened from the Western Ghats of India, 11 Mortierella i...

journal_title：BioMed research international

authors： Vadivelan G,Venkateswaran G

更新日期：2014-01-01 00:00:00

abstract：:An excessive pulmonary inflammatory response could explain the poor prognosis of chronic obstructive pulmonary disease (COPD) patients submitted to invasive mechanical ventilation. The aim of this study was to evaluate the response to normal tidal volume mechanical ventilation in an elastase-induced murine model of pu...

journal_title：BioMed research international

authors： Rouze A,Voiriot G,Guivarch E,Roux F,Tran Van Nhieu J,Isabey D,Brochard L,Maitre B,Mekontso-Dessap A,Boczkowski J

更新日期：2018-12-19 00:00:00

abstract：Background:In peritoneal dialysis (PD) patients, whether angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) could protect residual renal function is still controversial. To assess the effects of ACEIs and ARBs on the residual renal function and cardiovascular (CV) events in perito...

journal_title：BioMed research international

authors： Ding L,Yang J,Li L,Yang Y

更新日期：2020-09-23 00:00:00

abstract：Purpose:We evaluated the efficacies of the adaptive steepest descent projection onto convex sets (ASD-POCS), simultaneous algebraic reconstruction technique (SART), filtered back projection (FBP), and maximum likelihood expectation maximization (MLEM) total variation minimization iterative algorithms for reducing expos...

journal_title：BioMed research international

authors： Gomi T,Koibuchi Y

更新日期：2018-06-19 00:00:00

abstract：Background:A multifactorial decision support system (mDSS) is a tool designed to improve the clinical decision-making process, while using clinical inputs for an individual patient to generate case-specific advice. The study provides an overview of the literature to analyze current available mDSS focused on prostate ca...

journal_title：BioMed research international

authors： van Wijk Y,Halilaj I,van Limbergen E,Walsh S,Lutgens L,Lambin P,Vanneste BGL

更新日期：2019-06-06 00:00:00

abstract：:[This retracts the article DOI: 10.1155/2014/479180.]. ...

journal_title：BioMed research international

authors： BioMed Research International

更新日期：2016-01-01 00:00:00

abstract：:Over the years, studies have demonstrated morphological changes in the brain of fibromyalgia (FMS). We aimed to conduct a coordinate-based meta-analytic research through systemic review on voxel-based morphometry (VBM) imaging results to identify consistent gray matter (GM) difference between FMS patients and healthy ...

journal_title：BioMed research international

authors： Lin C,Lee SH,Weng HH

更新日期：2016-01-01 00:00:00

abstract：:This study aimed to develop a new biodegradable stent for peripheral artery disease (PAD) that could provide sufficient radial force to maintain long-term patency and flexibility. All self-expandable hybrid biodegradable stents were designed by using a knitting structure composed of poly-L-lactic acid (PLLA) and nitin...

journal_title：BioMed research international

authors： Lee JH,Kim SJ,Park SI,Ko YG,Choi D,Hong MK,Jang Y

更新日期：2016-01-01 00:00:00

abstract：:The expression profile of long noncoding RNA (lncRNA) in human epicardial adipose tissue (EAT) has not been widely studied. In the present study, we performed RNA sequencing to analyze the expression profiles of lncRNA and mRNA in EAT in coronary artery disease (CAD) patients with and without heart failure (HF). Our r...

journal_title：BioMed research international

authors： Zheng M,Zhao L,Yang X

更新日期：2019-07-04 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：:This study is to investigate multiple chemotherapeutic agent- and radiation-related genetic biomarkers in locally advanced rectal cancer (LARC) patients following fluoropyrimidine-based concurrent chemoradiotherapy (CCRT) for response prediction. We initially selected 6 fluoropyrimidine metabolism-related genes (DPYD,...

journal_title：BioMed research international

authors： Huang MY,Wu CH,Huang CM,Chung FY,Huang CW,Tsai HL,Chen CF,Lin SR,Wang JY

更新日期：2013-01-01 00:00:00

abstract：:Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane h...

journal_title：BioMed research international

authors： Gabarre S,Herrera A,Mateo J,Ibarz E,Lobo-Escolar A,Gracia L

更新日期：2014-01-01 00:00:00

abstract：:Biliary atresia (BA) is an orphan medical condition of the newborn, resulting in end-stage liver cirrhosis due to obliterative cholangiopathy of the extrahepatic bile duct. Although Kasai's hepatoportoenterostomy (KPE) is the well-established first-line therapy, little is known about its surgical complications. 153 pa...

journal_title：BioMed research international

authors： Madadi-Sanjani O,Carl N,Longerich T,Petersen C,Andruszkow JH

更新日期：2015-01-01 00:00:00