Abstract:
:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h of incubation. aEPEC strains representing each HEp-2 cell type of adherence were analyzed after 24 h and 6, 12, and 18 days of incubation at 37°C on abiotic and cell surfaces by CFU/cm(2) counting and confocal laser scanning microscopy (CLSM). Biofilm formation on abiotic surfaces occurred in 55 (60.4%) of the aEPEC strains. There was no significant difference in biofilm biomass formation on an abiotic versus prefixed cell surface. The biofilms could be visualized by CLSM at various developmental stages. aEPEC strains are able to form biofilm on an abiotic surface with no association with their adherence pattern on HEp-2 cells with the exception of the strains expressing UND (undetermined adherence). This study revealed the capacity of adhesion and biofilm formation by aEPEC strains on abiotic and biotic surfaces, possibly playing a role in pathogenesis, mainly in cases of persistent diarrhea.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MRdoi
10.1155/2014/845147subject
Has Abstractpub_date
2014-01-01 00:00:00pages
845147eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
杂志文章abstract::More than one-third of the world's population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease. The severity of the disease is strongly...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/913696
更新日期:2014-01-01 00:00:00
abstract::Parkinson's disease (PD) is a major neurodegenerative disorder for which the etiology and pathogenesis remain as elusive as for Alzheimer's disease. PD appears to be caused by genetic and environmental factors, and pedigree and cohort studies have identified numerous susceptibility genes and loci related to PD. Autoso...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/371256
更新日期:2014-01-01 00:00:00
abstract::Hematopoietic stem cells (HSCs) are unique in their capacity to give rise to all mature cells of the immune system. For years, HSC transplantation has been used for treatment of genetic and neoplastic diseases of the hematopoietic and immune systems. The sourcing of HSCs from human umbilical cord blood has salient adv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/740892
更新日期:2013-01-01 00:00:00
abstract::We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent storage stability an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/471468
更新日期:2015-01-01 00:00:00
abstract:Background:The well-known rubber hand paradigm induces an illusion by having participants feel the touch applied to a fake hand. In parallel, the kinesthetic mirror illusion elicits illusions of movement by moving the reflection of a participant's arm. Experimental manipulation of sensory inputs leads to emergence of t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/6937328
更新日期:2017-01-01 00:00:00
abstract::Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/365050
更新日期:2015-01-01 00:00:00
abstract:Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/6360459
更新日期:2019-07-15 00:00:00
abstract::We test the hypothesis that ultrasound-targeted microbubble destruction (UTMD) technique increases the renoprotective effect of kidney-targeted transplantation of bone-marrow-derived mesenchymal stem cells (BM-MSCs) in diabetic nephropathy (DN) rats. Diabetes was induced by streptozotocin injection (60 mg/Kg, intraper...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/526367
更新日期:2013-01-01 00:00:00
abstract::Accurately annotating biological functions of proteins is one of the key tasks in the postgenome era. Many machine learning based methods have been applied to predict functional annotations of proteins, but this task is rarely solved by deep learning techniques. Deep learning techniques recently have been successfully...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/1729301
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Although binge drinking prevalence and correlates among young people have been extensively studied in the USA and Northern Europe, less is known for Southern Europe countries with relatively healthier drinking cultures. OBJECTIVE:We aimed at analyzing prevalence and correlates of binge drinking in a represe...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/930795
更新日期:2014-01-01 00:00:00
abstract::Ischemia/reperfusion (I/R) injury remains a major complication of liver resection, transplantation, and hemorrhagic shock. Although the mechanisms that contribute to hepatic I/R are complex and diverse involving the interaction of cell injury in hepatocytes, immune cells, and endothelium, mitochondrial dysfunction is ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/183469
更新日期:2015-01-01 00:00:00
abstract::Otitis media (OM) is a common inflammatory disease of the middle ear cavity and mainly occurs in children. As a critical regulator of inflammation response, the nuclear factor kappa B (NF-κB) pathway has been found to play an essential role in the pathogenesis of various human diseases. The aim of this study was to ex...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2021/8844119
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Parents' birth weight acts as a predictor for the descendant birth weight, with the correlation more strongly transmitted through maternal line. The present research aims to study the correlation between the child's low or increased birth weight, the mother's birth weight, and maternal conditi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/615034
更新日期:2015-01-01 00:00:00
abstract::Although multimodal therapies including surgery, chemotherapy, and radiotherapy have improved clinical outcomes of patients with bone and soft tissue sarcomas, the prognosis of patients has plateaued over these 20 years. Immunotherapies have shown the effectiveness for several types of advanced tumors. Immunotherapies...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/820813
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. AIMS:To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW) in male Wistar rats. METHODS:Eighteen male Wistar rats were fed with FDW 20%...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/263897
更新日期:2014-01-01 00:00:00
abstract::Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediter...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/839019
更新日期:2014-01-01 00:00:00
abstract::The purpose of the present study was to examine the convergent and divergent validity of the Biber Cognitive Estimation Test (BCET) in individuals with ABI undergoing postacute rehabilitation and to assess the measure's ability to account for unique variance in community integration following rehabilitation. Participa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2874819
更新日期:2017-01-01 00:00:00
abstract::One of the biggest obstetric challenges is the diagnosis and management of a short cervix as cervical length has an inverse relationship with risk of preterm birth. A cervical cerclage is a surgical procedure to reduce the risk of preterm birth and can be placed in an elective or emergency setting. This is a retrospec...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1155/2018/2065232
更新日期:2018-09-30 00:00:00
abstract::The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 20...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/8718053
更新日期:2018-01-09 00:00:00
abstract::Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness amon...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2543262
更新日期:2017-01-01 00:00:00
abstract::In the present study, we determined whether there is a delay in the eruption of permanent teeth (PT) among Filipino adolescents with stunting or thinness. Height, weight, and number of PT were recorded in 1554 Filipino 10- to 13-year-olds (711 boys; 843 girls). z-scores for height (HAZ) and body mass index (BMI) were ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/205950
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To analyze the clinical relevance of the levels of TNFα blockers and anti-drug antibodies (anti-drug Ab) in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) treated with adalimumab (ADA), etanercept (ETA), or infliximab (INF) for a prolonged period of time. METHODS:Clinical characteristics...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/604872
更新日期:2015-01-01 00:00:00
abstract::Bovine pericardium is used for heart valve leaflet replacement where the strength and thinness are critical properties. Pericardium from neonatal animals (4-7 days old) is advantageously thinner and is considered as an alternative to that from adult animals. Here, the structures of adult and neonatal bovine pericardiu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/189197
更新日期:2014-01-01 00:00:00
abstract::Vocal tract morphology is an important factor in voice production. Its analysis has potential implications for educational matters as well as medical issues like voice therapy. The knowledge of the complex adjustments in the spatial geometry of the vocal tract during phonation is still limited. For a major part, this ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/906356
更新日期:2015-01-01 00:00:00
abstract::Because of their high incidence and mortality solid cancers are a major health problem worldwide. Although several new biomarkers and potential targets for therapy have been identified through biomolecular research in the last years, the effects on patients' outcome are still unsatisfactory. Increasing evidence indica...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/896432
更新日期:2015-01-01 00:00:00
abstract::The aim of the study was to find out whether peripheral blood leukocyte adiponectin receptors 1 and 2 (AdipoR1, AdipoR2) protein expression patterns (flow cytometry) differ between the primary hypertension children (n = 57) and healthy controls (n = 19) and if their expression levels are related to selected clinical p...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/742646
更新日期:2015-01-01 00:00:00
abstract::The main objective was to quantify the effects of five different slopes on trunk and shoulder kinematics as well as shoulder kinetic and muscular demands during manual wheelchair (MWC) propulsion on a motorized treadmill. Eighteen participants with spinal cord injury propelled their MWC at a self-selected constant spe...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/636319
更新日期:2015-01-01 00:00:00
abstract::Objective. To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 -...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/4193538
更新日期:2016-01-01 00:00:00
abstract::We measured 28 parameters of 202 femurs from Koreans by an automated geometric computation program using 3D models generated from computed tomography images. The measurement parameters were selected with reference to physical and forensic anthropology studies as well as orthopedic implant design studies. All measureme...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/730538
更新日期:2015-01-01 00:00:00
abstract:Objective:This study aims to (i) translate, culturally adapt, and preliminarily validate the arrhythmia-specific Umea22 (U22) questionnaire and (ii) assess the impact of radiofrequency (RF) ablation and medical treatment on the quality of life of patients with supraventricular tachycardias (SVTs). Methods:A total of 1...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3059478
更新日期:2018-10-09 00:00:00