Prevalence and correlates of binge drinking among young adults using alcohol: a cross-sectional survey.

abstract：:Type 1 diabetes (T1D), a chronic autoimmune disease, is often preceded by a preclinical phase of islet autoimmunity (IA) where the insulin-producing beta cells of the pancreas are destroyed and circulating autoantibodies can be detected. The goal of this study was to demonstrate methods for identifying exposures that ...

journal_title：BioMed research international

authors： Frederiksen BN,Kroehl M,Barón A,Lamb MM,Crume TL,Sontag MK,Rewers M,Norris JM

更新日期：2015-01-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...

journal_title：BioMed research international

authors： Lee S,Kim Y,Kwon MS,Park T

更新日期：2015-01-01 00:00:00

abstract：:The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis. This study, aimed to investigate whether exosomes originated from bone marrow-derived MSCs (BMSCs) preconditioned by deferoxamine (DFO-Exos)...

journal_title：BioMed research international

authors： Ding J,Wang X,Chen B,Zhang J,Xu J

更新日期：2019-05-05 00:00:00

abstract：:The increased use of imaging modalities in the last years has led to a greater incidence in depicting abdominal incidental lesions. In particular, "incidentalomas" of the kidney are discovered in asymptomatic patients or patients who suffer from diseases not directly related to the kidneys. The aim of this paper is to...

journal_title：BioMed research international

authors： Mazziotti S,Cicero G,D'Angelo T,Marino MA,Visalli C,Salamone I,Ascenti G,Blandino A

更新日期：2017-01-01 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：:Psoriasis is one of the most prevalent immune mediated skin diseases worldwide. Despite the large prevalence in both men and women, the pathogenesis of this disease has not yet been fully clarified. Nowadays, it is believed that psoriasis is most likely a T helper Th1/Th17 induced inflammatory disease. Stressful life ...

journal_title：BioMed research international

authors： Ceovic R,Mance M,Bukvic Mokos Z,Svetec M,Kostovic K,Stulhofer Buzina D

更新日期：2013-01-01 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...

journal_title：BioMed research international

authors： Zhang Y,Lin Y,Liu Q,Yuan X,Mao A,Liu Y,Li Q,Zheng J,Hu B,Yu F

更新日期：2018-01-16 00:00:00

abstract：:The present study evaluated the anti-inflammatory and analgesic effects of the superoxide dismutase mimetic agent tempol in superoxide anion-induced pain and inflammation. Mice were treated intraperitoneally with tempol (10-100 mg/kg) 40 min before the intraplantar injection of a superoxide anion donor, potassium supe...

journal_title：BioMed research international

authors： Bernardy CCF,Zarpelon AC,Pinho-Ribeiro FA,Calixto-Campos C,Carvalho TT,Fattori V,Borghi SM,Casagrande R,Verri WA Jr

更新日期：2017-01-01 00:00:00

abstract：:With the recent advancement in the field of ocular therapy, drug delivery approaches have been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. However the major drawbacks of the conventional drug deliv...

journal_title：BioMed research international

authors： Sahoo RK,Biswas N,Guha A,Sahoo N,Kuotsu K

更新日期：2014-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a central nervous system (CNS) disease resulting from a targeted autoimmune-mediated attack on myelin proteins in the CNS. The release of Th1 inflammatory mediators in the CNS activates macrophages, antibodies, and microglia resulting in myelin damage and the induction of neuropathic pain (N...

journal_title：BioMed research international

authors： Zhu W,Acosta C,MacNeil B,Cortes C,Intrater H,Gong Y,Namaka M

更新日期：2013-01-01 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the dise...

journal_title：BioMed research international

authors： Choi J,Kook MS

更新日期：2015-01-01 00:00:00

abstract：:Body weight supported locomotor training uses neuroplasticity principles to improve recovery following a spinal cord injury (SCI). Steady state locomotion using the same body weight support (BWS) percent was compared in 7 males (42.6 ± 4.29 years) with incomplete SCI and matched (gender, age) noninjured controls (42.7...

journal_title：BioMed research international

authors： Fenuta AM,Hicks AL

更新日期：2014-01-01 00:00:00

abstract：Background:A deficiency in steroid 5α-reductase type 2 is an autosomal recessive disorder. Affected individuals manifested ambiguous genitalia, which is caused by decreased dihydrotestosterone (DHT) synthesis in the fetus. Methods:We analyzed 25 patients with 5α-reductase deficiency in China. Seventeen of the 25 patie...

journal_title：BioMed research international

authors： Han B,Cheng T,Zhu H,Yu J,Zhu WJ,Song HD,Yao H,Qiao J

更新日期：2020-06-09 00:00:00

abstract：:As emerging tick born rickettsial diseases caused by A. phagocytophilum and E. chaffeensis, anaplasmosis and ehrlichiosis have become a serious threat to human and animal health throughout the world. In particular, in China, an unusual transmission of nosocomial cases of human granulocytic anaplasmosis occurred in Anh...

journal_title：BioMed research international

authors： Zhang L,Liu H,Xu B,Zhang Z,Jin Y,Li W,Lu Q,Li L,Chang L,Zhang X,Fan D,Cao M,Bao M,Zhang Y,Guan Z,Cheng X,Tian L,Wang S,Yu H,Yu Q,Wang Y,Zhang Y,Tang X,Yin J,Lao S,Wu B,Li J,Li W,Xu Q,Shi Y,Huan

更新日期：2014-01-01 00:00:00

abstract：:28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...

journal_title：BioMed research international

authors： Johari SA,Mohtar M,Mohammad SA,Sahdan R,Shaameri Z,Hamzah AS,Mohammat MF

更新日期：2015-01-01 00:00:00

abstract：:Background. Atrial natriuretic peptide (ANP) considerably influences blood pressure regulation through water and sodium homoeostasis. Several of the studies have utilized anonymous genetic polymorphic markers and made inconsequent claims about the ANP relevant disorders. Thus, we screened Insertion/Deletion (ID) and G...

journal_title：BioMed research international

authors： Ghodsian N,Ismail P,Ahmadloo S,Eskandarian N,Etemad A

更新日期：2016-01-01 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：Objective:To retrospectively investigate computed tomographic (CT) quantitative analysis of ground-glass opacity (GGO) volume percentage and morphologic features of resected lung adenocarcinomas according to epidermal growth factor receptor (EGFR) mutation status and subtypes. Methods:Amplification refractory mutation...

journal_title：BioMed research international

authors： Wang H,Guo H,Wang Z,Shan B,Lin J

更新日期：2019-03-06 00:00:00

abstract：:Although the dynamic motions and peptidyl transferase activity seem to be embedded in the rRNAs, the ribosome contains more than 50 ribosomal proteins (r-proteins), whose functions remain largely elusive. Also, the precise forms of some of these r-proteins, as being part of the ribosome, are not structurally solved du...

journal_title：BioMed research international

authors： Chang KC,Wen JD,Yang LW

更新日期：2015-01-01 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：:Influenza vaccination for health care personnel (HCP) is recommended particularly because it indirectly protects patients from contracting the disease. Vaccinating can therefore be interpreted as a prosocial act. However, HCP vaccination rates are often far too low to prevent nosocomial infections. Effective intervent...

journal_title：BioMed research international

authors： Böhm R,Betsch C,Korn L,Holtmann C

更新日期：2016-01-01 00:00:00

abstract：:The efficiency of oat bran and barley bran in lowering the induced hyperlipidemia and hypercholesterolemia in blood of male Albino rats (Rattus rattus) was studied. Twenty rats were divided into four groups each consisted of five rats and fed the specified test diets for eight weeks. The first group (G1) is the negati...

journal_title：BioMed research international

authors： El Rabey HA,Al-Seeni MN,Amer HM

更新日期：2013-01-01 00:00:00

abstract：:Coronary heart disease (CHD) has become one of the leading causes of death and functional impairment in the world. Hyperglycemia is associated with an increased risk of cardiovascular disease. It was speculated that miRNAs in peripheral blood were a primary parameter in discriminating CHD. The biological characteristi...

journal_title：BioMed research international

authors： Jiang Y,Liu N,Xue B,Hou J,Lin C,Ren J,Liu J

更新日期：2017-01-01 00:00:00

abstract：:The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal information about the clinical course, etiology, and prognosis of this complex disease. The prevalence of metabolic comorbiditie...

journal_title：BioMed research international

authors： Li X,Gao P,Niu J

更新日期：2019-08-18 00:00:00

abstract：:Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO antibody (monoclonal 72D9)...

journal_title：BioMed research international

authors： Matsubara E,Takamura A,Okamoto Y,Oono H,Nakata T,Wakasaya Y,Kawarabayashi T,Shoji M

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The primary aim of this study was to explore if classification, whether using the BI-RADS categories based on CEUS or conventional ultrasound, was conducive to the identification of benign and malignant category 3 or 4 small breast lesions. MATERIAL AND METHODS:We evaluated 30 malignant and 77 benign small bre...

journal_title：BioMed research international

authors： Zhang JX,Cai LS,Chen L,Dai JL,Song GH

更新日期：2014-01-01 00:00:00

abstract：:Biliary atresia (BA) is an orphan medical condition of the newborn, resulting in end-stage liver cirrhosis due to obliterative cholangiopathy of the extrahepatic bile duct. Although Kasai's hepatoportoenterostomy (KPE) is the well-established first-line therapy, little is known about its surgical complications. 153 pa...

journal_title：BioMed research international

authors： Madadi-Sanjani O,Carl N,Longerich T,Petersen C,Andruszkow JH

更新日期：2015-01-01 00:00:00

abstract：:Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce. Consequently, in the current paper, we focused on the Quadrato motor training (QMT), a newly developed whole-body movement-based MBP, which has been...

journal_title：BioMed research international

authors： Venditti S,Verdone L,Pesce C,Tocci N,Caserta M,Ben-Soussan TD

更新日期：2015-01-01 00:00:00

abstract：:This study aims to evaluate whether diets containing mixture of formic and propionic acid alone or supplemented with either capric acid or Bacillus Licheniformis can alleviate immune inflammatory response of piglets challenged with enterotoxigenic Escherichia coli (ETEC). A total of 30 weaning pigs were assigned to 5 ...

journal_title：BioMed research international

authors： Ren C,Zhou Q,Guan W,Lin X,Wang Y,Song H,Zhang Y

更新日期：2019-03-25 00:00:00