Cholesteryl Pullulan Encapsulated TNF-α Nanoparticles Are an Effective Mucosal Vaccine Adjuvant against Influenza Virus.

abstract：Background:BMPER has been reported to be associated with the biological behavior of a few malignant tumors, but the mechanism is still unclear. We aimed to detect BMPER expression in ovarian epithelial tumor tissues and its effects on their biological behaviors, as well as to elucidate the possible mechanism. Methods:...

journal_title：BioMed research international

authors： Xi Y,Nie X,Wang J,Gao L,Lin B

更新日期：2020-03-24 00:00:00

abstract：Objectives:Percutaneous coronary intervention (PCI) is the mainstay treatment for coronary artery disease but complications such as in-stent restenosis and thrombosis remain problematic. Radiofrequency balloon angioplasty (RBA) can improve lumen dimension, fusing intimal tears, and artery dissection but is associated w...

journal_title：BioMed research international

authors： Chen Q,Wang M,Shao S,Liu H,Xia X,Tse G,Yuan M,Zhang Y,Liang X,Liu T,Li G

更新日期：2018-12-23 00:00:00

abstract：:High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...

journal_title：BioMed research international

authors： Mardente S,Mari E,Massimi I,Fico F,Faggioni A,Pulcinelli F,Antonaci A,Zicari A

更新日期：2015-01-01 00:00:00

abstract：:Vitamin D is important for normal development and maintenance of the skeleton. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity, matrix ossification, bone remodeling and bone density. It is well known that Vit. D deficiency in the developing skeleton is related to rickets, while in adults ...

journal_title：BioMed research international

authors： Christodoulou S,Goula T,Ververidis A,Drosos G

更新日期：2013-01-01 00:00:00

abstract：:A Chinese medicinal fern Blechnum orientale (Linn) was separately collected from polluted and unpolluted sites to determine whether it could accumulate hazardous pollutants or not. Metal concentrations (Cu, Zn, Mn, Pb, Cd, Cr, As, and Hg) both in the fronds and roots and polycyclic aromatic hydrocarbons (PAHs) in the ...

journal_title：BioMed research international

authors： Zhu XM,Kuang YW,Xi D,Li J,Wang FG

更新日期：2013-01-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring significant high mortality and morbidity. The use of saliva, as a noninvasive tool for the diagnosis of cancer, has recently increased. Salivary mic...

journal_title：BioMed research international

authors： Salazar-Ruales C,Arguello JV,López-Cortés A,Cabrera-Andrade A,García-Cárdenas JM,Guevara-Ramírez P,Peralta P,Leone PE,Paz-Y-Miño C

更新日期：2018-11-21 00:00:00

abstract：:Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...

journal_title：BioMed research international

authors： Won G,Jung JH,Sohn EJ,Park JE,Kim H,Lee HJ,Shim BS,Kim SH

更新日期：2020-02-07 00:00:00

abstract：:Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...

journal_title：BioMed research international

authors： Caimmi M,Guanziroli E,Malosio M,Pedrocchi N,Vicentini F,Molinari Tosatti L,Molteni F

更新日期：2015-01-01 00:00:00

abstract：:Family planning coverage has improved in Ethiopia in the last decade, though fertility is still about 5.8 in the rural setup. In this paper, the major structural determinants of family planning service were analyzed using a multilevel model from 8906 individual women observation in the 2011 EDHS data. The results show...

journal_title：BioMed research international

authors： Gizachew Balew J,Cho Y,Tammy Kim C,Ko W

更新日期：2015-01-01 00:00:00

abstract：:Tuberculosis (TB) is a dangerous infectious disease characterized by a tight interplay between mycobacteria and host cells in granulomatous lesions (granulomas) during the latent, asymptomatic stage of infection. Mycobacterium-host cell relationships were analyzed in granulomas obtained from various organs of BALB/c m...

journal_title：BioMed research international

authors： Ufimtseva E

更新日期：2015-01-01 00:00:00

abstract：:MicroRNAs are small noncoding RNAs, involved in the regulation of many cellular processes in plants. Hundreds of miRNAs have been identified in cassava by various techniques, yet these identifications were constrained by a lack of miRNA templates and the narrow range of conditions in transcriptome study. In this resea...

journal_title：BioMed research international

authors： Yawichai A,Kalapanulak S,Thammarongtham C,Saithong T

更新日期：2019-06-19 00:00:00

abstract：Objective:To compare the expression of G-protein-coupled estrogen receptor (GPER) in the junctional zone and outer myometrium of the proliferative and secretory phases of women with and without adenomyosis. Methods:A total of 76 women were included in this study, 42 with adenomyosis (proliferative phase, n = 23; secre...

journal_title：BioMed research international

authors： Li JJ,Duan H,Wang S,Sun FQ,Gan L,Tang YQ,Xu Q,Li TC

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to ...

journal_title：BioMed research international

authors： Kadioglu TC,Aliyev E,Celtik M

更新日期：2014-01-01 00:00:00

abstract：:Otitis media (OM) is a common inflammatory disease of the middle ear cavity and mainly occurs in children. As a critical regulator of inflammation response, the nuclear factor kappa B (NF-κB) pathway has been found to play an essential role in the pathogenesis of various human diseases. The aim of this study was to ex...

journal_title：BioMed research international

authors： Yang X,Zhang Q,Lu H,Wang C,Xia L

更新日期：2021-01-06 00:00:00

abstract：:Purslane, a fleshy herbaceous plant, plays a pivotal role in various preventive and therapeutic purposes. To date, no report has documented the consequence of salt stress on metabolite accumulation in purslane. Herein, we proposed an insight into the metabolic and physiological traits of purslane under saline stress e...

journal_title：BioMed research international

authors： Zaman S,Bilal M,Du H,Che S

更新日期：2020-06-17 00:00:00

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00

abstract：:Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, researches on the deve...

journal_title：BioMed research international

authors： Ding X,Liu TD,Xie ZL,Zhao Q,Cao Y,Liu XD,Wang CH,Gamariel RR,Ming X,Li ZY,Kong Y

更新日期：2016-01-01 00:00:00

abstract：Background:Inconsistent data have been reported for the effectiveness of intramuscular botulinum toxin type A (BTXA) in patients with limb spasticity after stroke. This meta-analysis of available randomized controlled trials (RCTs) aimed to determine the efficacy and safety of BTXA in adult patients with upper and lowe...

journal_title：BioMed research international

authors： Sun LC,Chen R,Fu C,Chen Y,Wu Q,Chen R,Lin X,Luo S

更新日期：2019-04-07 00:00:00

abstract：:Schistosomiasis is the most prevalent tropical disease in the world after malaria. According to the World Health Organization, the disease afflicts more than 240 million people in about 80 countries. Recently, an epidemiological surveillance study performed between 1997 and 2010 by the European Network for Tropical Me...

journal_title：BioMed research international

authors： Brindicci G,Santoro CR,De Laurentiis V,Capolongo C,Solarino ME,Papagni R,Ciracì E,Gatti P,Loconsole D,Monno R,Monno L,Miragliotta G,Angarano G

更新日期：2017-01-01 00:00:00

abstract：:Background. The chronic recommendation of pediatric drugs could exhibit erosive and cariogenic problems. Objective. To evaluate the effects of different pediatric drugs on the color stability of various restorative materials. Methods. Five specimens (1 mm × 3 mm) were prepared and immersed in ten different pediatric d...

journal_title：BioMed research international

authors： Tüzüner T,Turgut S,Baygin O,Yilmaz N,Tuna EB,Ozen B

更新日期：2017-01-01 00:00:00

abstract：:Angiogenesis and lymphangiogenesis are important in the proliferation and survival of the malignant hematopoietic neoplasms, including non-Hodgkin's lymphomas (NHLs). Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) play an important role in the initiation of angiogenesis. Both VEGF ...

journal_title：BioMed research international

authors： Wróbel T,Mazur G,Dzietczenia J,Gębura K,Kuliczkowski K,Bogunia-Kubik K

更新日期：2013-01-01 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:Little is known about how prenatal maternal stress (PNMS) influences risks of asthma in humans. In this small study, we sought to determine whether disaster-related PNMS would predict asthma risk in children. In June 1998, we assessed severity of objective hardship and subjective distress in women pregnant during the ...

journal_title：BioMed research international

authors： Turcotte-Tremblay AM,Lim R,Laplante DP,Kobzik L,Brunet A,King S

更新日期：2014-01-01 00:00:00

abstract：:Data on genotypic diversity of Mycobacterium tuberculosis complex (MTBC) is important to understand its epidemiology, human adaptation, clinical phenotypes, and drug resistance. This study aimed to characterize MTBC clinical isolates circulating in a predominantly pastoralist area in Ethiopia, a country where tubercul...

journal_title：BioMed research international

authors： Belay M,Ameni G,Bjune G,Couvin D,Rastogi N,Abebe F

更新日期：2014-01-01 00:00:00

abstract：Background:Methadone Maintenance Treatment (MMT) program's success depends on the likelihood of reducing drop-out rate and keeping patients remaining in the program. There have been neither comprehensive studies about variation among patients who have been experiencing MMT for long period nor prediction of MMT period i...

journal_title：BioMed research international

authors： Dao ATM,Nguyen HTT,Nguyen LH

更新日期：2018-08-07 00:00:00

abstract：:Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...

journal_title：BioMed research international

authors： Adamska E,Ostrowska L,Gościk J,Waszczeniuk M,Krętowski A,Górska M

更新日期：2015-01-01 00:00:00

abstract：:Enzymes play important roles in most of the biological processes. Although only a small fraction of residues are directly involved in catalytic reactions, these catalytic residues are the most crucial parts in enzymes. The study of the fundamental and unique features of catalytic residues benefits the understanding of...

journal_title：BioMed research international

authors： Chien YT,Huang SW

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To assess whether high-molecular-weight proteins excretion predicts outcome and therapy-responsiveness in patients with FSGS and nephrotic syndrome. RESEARCH DESIGN AND METHODS:Thirty-eight patients measured at biopsy fractional excretion of IgG (FEIgG) and urinary α2-macroglobulin/creatinine ratio ( α m/C)....

journal_title：BioMed research international

authors： Bazzi C,Rizza V,Casellato D,Stivali G,Rachele G,Napodano P,Gallieni M,D'Amico G

更新日期：2013-01-01 00:00:00

abstract：:L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is primarily due to enzymatic activity, but other mechanisms have been proposed recently which require further investigation. L-amino acid oxidases ex...

journal_title：BioMed research international

authors： Izidoro LF,Sobrinho JC,Mendes MM,Costa TR,Grabner AN,Rodrigues VM,da Silva SL,Zanchi FB,Zuliani JP,Fernandes CF,Calderon LA,Stábeli RG,Soares AM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Obesity has become a global epidemic due to an increase in the number of obese individuals worldwide. There is little research in the field of obesity genetics in Pakistan. The aim of the current study was to analyze the association of common variants in Fat Mass and Obesity associated (FTO) gene w...

journal_title：BioMed research international

authors： Shabana,Hasnain S

更新日期：2015-01-01 00:00:00