Protein Function Prediction Using Deep Restricted Boltzmann Machines.

abstract：:We aimed to determine the effects of an 8 wk Hatha yoga training on blood glucose, insulin, lipid profiles, endothelial microparticles (EMPs), and inflammatory status in healthy, lean, and female Chinese subjects. A total of 30 healthy, female Chinese subjects were recruited and randomized into control or yoga practic...

journal_title：BioMed research international

authors： Chen N,Xia X,Qin L,Luo L,Han S,Wang G,Zhang R,Wan Z

更新日期：2016-01-01 00:00:00

abstract：:Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carrier (NLC) to produce...

journal_title：BioMed research international

authors： Foong JN,Selvarajah GT,Rasedee A,Rahman HS,How CW,Beh CY,Teo GY,Ku CL

更新日期：2018-10-15 00:00:00

abstract：Background:Pakistan is a country with one of the highest burden of tuberculosis (TB) in the world, and therefore, it is imperative to revisit the design of behaviour change interventions in the program. This study was designed to understand and assess the knowledge, awareness, perceptions, and health-seeking behaviour ...

journal_title：BioMed research international

authors： Khan A,Shaikh BT,Baig MA

更新日期：2020-04-21 00:00:00

abstract：:The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

journal_title：BioMed research international

authors： Guevara L,Antolinos V,Palop A,Periago PM

更新日期：2015-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：Background:Pyroptosis, a novel form of inflammatory programmed cell death, was recently found to be a cause of mucosal barrier defect. In our pervious study, CD147 expression was documented to increase in intestinal tissue of inflammatory bowel disease (IBD). Objective:The aim of this study was to determine the functi...

journal_title：BioMed research international

authors： Xu Z,Liu R,Huang L,Xu Y,Su M,Chen J,Geng L,Xu W,Gong S

更新日期：2020-06-30 00:00:00

abstract：:The purpose of this study is to evaluate the therapeutic effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) activated by curcumin (CUR) on PC12 cells induced by 1-methyl-4-phenylpyridinium ion (MPP+), a cell model of Parkinson's disease (PD). The supernatant of hUC-MSC and hUC-MSC activated by 5 ...

journal_title：BioMed research international

authors： Jinfeng L,Yunliang W,Xinshan L,Yutong W,Shanshan W,Peng X,Xiaopeng Y,Zhixiu X,Qingshan L,Honglei Y,Xia C,Hongwei W,Bingzhen C

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Thiopurine drugs are metabolized via S-methylation and catalyzed by thiopurine S-methyltransferase (TPMT). Patients with very low TPMT activity are at high risk of fatal bone marrow toxicity when standard doses of thiopurine drugs are administered. TPMT genotyping can predict TPMT activity and is not affec...

journal_title：BioMed research international

authors： Kim S,Lee HW,Lee W,Chun S,Min WK

更新日期：2013-01-01 00:00:00

abstract：Background:Health-related physical fitness is vital for children with intellectual and developmental disabilities (IDD) to gain healthier lives. The adapted rhythmic gymnastics (ARG) program was designed for children with IDD and is aimed at testing the effects of the exercise program on children's physical fitness. M...

journal_title：BioMed research international

authors： Xu C,Yao M,Kang M,Duan G

更新日期：2020-08-10 00:00:00

abstract：:Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous antagonist, has been im...

journal_title：BioMed research international

authors： He T,Zhao L,Zhang D,Zhang Q,Jia J,Hu J,Huang Y

更新日期：2015-01-01 00:00:00

abstract：Purpose:This study aims to compare the functional outcomes of nonunion humeral diaphyseal fractures following conservative treatment when managed surgically with either a plate or intramedullary (IM) nail fixation. Methods:This was a retrospective study of 56 patients with nonunion humeral fractures following conserva...

journal_title：BioMed research international

authors： Micic I,Kholinne E,Kwak JM,Sun Y,Nanda A,Kim H,Koh KH,Jeon IH

更新日期：2019-07-22 00:00:00

abstract：:The new chemokine Prokineticin 2 (PROK2) and its receptors (PKR1 and PKR2) have a role in inflammatory pain and immunomodulation. Here we identified PROK2 as a critical mediator of neuropathic pain in the chronic constriction injury (CCI) of the sciatic nerve in mice and demonstrated that blocking the prokineticin rec...

journal_title：BioMed research international

authors： Lattanzi R,Maftei D,Marconi V,Florenzano F,Franchi S,Borsani E,Rodella LF,Balboni G,Salvadori S,Sacerdote P,Negri L

更新日期：2015-01-01 00:00:00

abstract：Introduction:SATIS-Stroke was developed to measure satisfaction regarding activities and participation among stroke survivors based on the concepts contained in the International Classification of Functioning, Disability, and Health. However, this measure is only available in English and French. Objective:Perform the ...

journal_title：BioMed research international

authors： Pereira GS,Silva SM,Júlio CE,Thonnard JL,Bouffioulx E,Corrêa JCF,Corrêa FI

更新日期：2019-02-18 00:00:00

abstract：:28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...

journal_title：BioMed research international

authors： Johari SA,Mohtar M,Mohammad SA,Sahdan R,Shaameri Z,Hamzah AS,Mohammat MF

更新日期：2015-01-01 00:00:00

abstract：:This study was conducted to determine the effects of feeding oil palm frond silage based diets with added linseed oil (LO) containing high α -linolenic acid (C18:3n-3), namely, high LO (HLO), low LO (LLO), and without LO as the control group (CON) on the fatty acid (FA) composition of subcutaneous adipose tissue and t...

journal_title：BioMed research international

authors： Ebrahimi M,Rajion MA,Goh YM,Sazili AQ,Schonewille JT

更新日期：2013-01-01 00:00:00

abstract：:The valorization of Crocus sativus L. by-products has become important given its interesting content of bioactive molecules. In the present study, aqueous tepal extract (ATE) studied eggplant seedling's growth and physiology under a plastic tunnel. ATE was foliage sprayed 3 times every 15 days, with various concentrat...

journal_title：BioMed research international

authors： Khoulati A,Ouahhoud S,Mamri S,Meziane M,Choukri M,Asehraou A,Saalaoui E

更新日期：2020-11-05 00:00:00

abstract：OBJECTIVE:To explore the safety and efficacy of transpseudarthrosis osteotomy with interbody fusion in the treatment of Ankylosing Spondylitis (AS) patients with kyphotic spinal pseudarthrosis by a single posterior approach. METHODS:Twelve consecutive patients with spinal pseudarthrosis underwent transpseudarthrosis o...

journal_title：BioMed research international

authors： Yang E,Cao L,Zhang G,Lian X,Xu J

更新日期：2017-01-01 00:00:00

abstract：:The aim of the present paper was to review the most important mechanisms explaining the possible association of vitamin D deficiency and cardiovascular diseases, focusing on recent experimental and clinical data. Low vitamin D levels favor atherosclerosis enabling vascular inflammation, endothelial dysfunction, format...

journal_title：BioMed research international

authors： Mozos I,Marginean O

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2015/714230.]. ...

journal_title：BioMed research international

authors： Voss JO,Loebel C,Bara JJ,Fuessinger MA,Duttenhoefer F,Alini M,Stoddart MJ

更新日期：2016-01-01 00:00:00

abstract：:Hilar cholangiocarcinoma (HCC) remains one of the most difficult tumors to stage and treat. The aim of the study was to assess the diagnostic efficiency of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computer tomography (PET/CT) in evaluating the resectability of HCC. A...

journal_title：BioMed research international

authors： Zhang H,Zhu J,Ke F,Weng M,Wu X,Li M,Quan Z,Liu Y,Zhang Y,Gong W

更新日期：2015-01-01 00:00:00

abstract：:Acetabular fractures involving predominantly the anterior column associated with a disruption of the quadrilateral surface can be treated with instrumentation implementing the stabilization of the quadrilateral surface. The recently introduced suprapectineal quadrilateral buttress plate is specifically designed to pre...

journal_title：BioMed research international

authors： Egli RJ,Keel MJB,Cullmann JL,Bastian JD

更新日期：2017-01-01 00:00:00

abstract：:To identify novel susceptibility genes and gene sets for obesity, we conducted a genomewide expression association analysis of obesity via integrating genomewide association study (GWAS) and expression quantitative trait loci (eQTLs) data. GWAS summary data of body mass index (BMI) and waist-to-hip ratio (WHR) was dri...

journal_title：BioMed research international

authors： Liu L,Fan Q,Zhang F,Guo X,Liang X,Du Y,Li P,Wen Y,Hao J,Wang W,He A

更新日期：2018-05-08 00:00:00

abstract：:Tau tubulin kinase 2 (TTBK2) is a kinase known to phosphorylate tau and tubulin. It has recently drawn much attention due to its involvement in multiple important cellular processes. Here, we review the current understanding of TTBK2, including its sequence, structure, binding sites, phosphorylation substrates, and ce...

journal_title：BioMed research international

authors： Liao JC,Yang TT,Weng RR,Kuo CT,Chang CW

更新日期：2015-01-01 00:00:00

abstract：:Purpose. The aim of the present study was to elucidate the metabolic mechanisms associated with chronic fatigue syndrome (CFS) via an analysis of urine metabolites prior to and following exercise in a rat model. Methods. A rat model of CFS was established using restraint-stress, forced exercise, and crowded and noisy ...

journal_title：BioMed research international

authors： Shao C,Ren Y,Wang Z,Kang C,Jiang H,Chi A

更新日期：2017-01-01 00:00:00

abstract：:Breast cancer is the leading cause of death in women worldwide. The search for novel compounds with antitumor activity, with less adverse effects and higher efficacy, and the development of methods to evaluate their toxicity is an area of intense research. In this study we implemented the preparation and culture of br...

journal_title：BioMed research international

authors： Carranza-Torres IE,Guzmán-Delgado NE,Coronado-Martínez C,Bañuelos-García JI,Viveros-Valdez E,Morán-Martínez J,Carranza-Rosales P

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to compare within-subject blood pressure (BP) variabilities from different measurement techniques. Cuff pressures from three repeated BP measurements were obtained from 30 normotensive and 30 hypertensive subjects. Automatic BPs were determined from the pulses with normalised peak amplitude larger tha...

journal_title：BioMed research international

authors： Yang F,Chen F,Zhu M,Chen A,Zheng D

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The vasoconstrictor endothelin-1 (ET-1) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid hemorrhage (SAH). Previous results showed that CGS 26303, an endothelin converting enzyme (ECE) inhibitor, effectively prevented and reversed arterial narrowing in animal m...

journal_title：BioMed research international

authors： Wang CJ,Lee PY,Wu BN,Wu SC,Loh JK,Tsai HP,Chung CL,Kassell NF,Kwan AL

更新日期：2014-01-01 00:00:00

abstract：Objectives:Magnetic resonance imaging (MRI) and in particular diffusion-weighted imaging (DWI) have been broadly proven to be the reference imaging method to discriminate between cholesteatoma and noncholesteatomatous middle ear lesions, especially when high tissue specificity is required. The aim of this study is to d...

journal_title：BioMed research international

authors： Russo C,Elefante A,Di Lullo AM,Carotenuto B,D'Amico A,Cavaliere M,Iengo M,Brunetti A

更新日期：2018-04-24 00:00:00

abstract：:Medicinal plants have played an important role in the treatment of many diseases. Medicinal plants are believed to be well appropriate with the human body and to produce less side influences than the pharmaceuticals. Kingdom of Saudi Arabia has abundant and wide variety of medicinal plants whose therapeutic effects ha...

journal_title：BioMed research international

authors： Almalki DA,Alghamdi SA,Al-Attar AM

更新日期：2019-02-27 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00