Impact of Radiofrequency Ablation and Antiarrhythmic Medications on the Quality of Life of Patients with Supraventricular Tachycardias: Preliminary Validation of the Greek Version of the Umea22 (U22) Questionnaire.

Abstract:

Objective:This study aims to (i) translate, culturally adapt, and preliminarily validate the arrhythmia-specific Umea22 (U22) questionnaire and (ii) assess the impact of radiofrequency (RF) ablation and medical treatment on the quality of life of patients with supraventricular tachycardias (SVTs). Methods:A total of 140 patients with atrioventricular nodal re-entry tachycardia (AVNRT) and atrioventricular re-entry tachycardia (AVRT) were enrolled in the study. Of these, 100 patients underwent RF ablation (group A) and 40 patients were managed with antiarrhythmic medications (group B). Health-related quality of life (HRQoL) was assessed for both groups using the Short Form-36 Health Survey (SF-36) and the arrhythmia-specific Umea22 (U22) questionnaire at baseline and 3-month follow-up. Exploratory and confirmatory factor analyses were performed to assess the validity of the U22 questionnaire. Univariate comparisons of HRQoL scores between study timepoints and multivariate regression analyses adjusting for baseline confounders were conducted. Results:The factor analysis of the U22 questionnaire yielded a six-factor model ("burden of spells"; "heart contractility"; "character of spells"; "general/non-specific feeling"; "other specific somatic symptoms"; "fear") with acceptable fit results. Patients of group A showed significant improvement in all SF-36 and U22 scores at 3 months' follow-up compared to baseline (all p<0.05). Patients of group B presented deterioration of the total SF-36 score (p=0.001) and improvement of certain U22 measures, namely, well-being (p=0.004), heartbeat speed, and intensity during arrhythmia spells (p<0.0001 for both measures) at 3 months' follow-up, compared to baseline. Employment status, male sex, and urban residence emerged as important predictors. Conclusion:The Greek version of the U22 questionnaire is a valid tool to assess SVT-related symptoms. RF ablation appears to exert more pronounced beneficial outcomes on HRQoL of patients with SVTs compared to medical treatment. Prompt referral of patients with SVTs to specialist centers may favorably affect their quality of life and should be encouraged.

journal_name

Biomed Res Int

authors

Domeyer PR,Giannakidou SC,Kyriakou P,Katsari V,Antoniadis AP,Lagos IK,Fragakis N,Varaklioti A,Vassilikos VP

doi

10.1155/2018/3059478

subject

Has Abstract

pub_date

2018-10-09 00:00:00

pages

3059478

eissn

2314-6133

issn

2314-6141

journal_volume

2018

pub_type

杂志文章
  • Identification and Functional Mechanism of Novel Angiotensin I Converting Enzyme Inhibitory Dipeptides from Xerocomus badius Cultured in Shrimp Processing Waste Medium.

    abstract::ACE inhibitory dipeptides from Xerocomus badius fermented shrimp processing waste were isolated with ethanol, macroporous resin, chloroform, and Sephadex G-10 in sequence and identified by LC-MS/MS system coupled with electrospray ionization source. Molecular docking was performed for exploring the mechanism of their ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/5089270

    authors: Gao X,Li X,Yan P,Sun R,Kan G,Zhou Y

    更新日期:2018-05-08 00:00:00

  • Potential Relationship between Clinical Significance and Serum Exosomal miRNAs in Patients with Multiple Myeloma.

    abstract::This study evaluated the potential relationship between exosomal miRNAs and clinical symptoms in patients with multiple myeloma (MM). Forty-eight newly diagnosed myeloma patients and sixteen normal donors were enrolled in the study. The results showed that the relative expression levels of let-7c-5p, let-7d-5p, miR-14...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/1575468

    authors: Zhang ZY,Li YC,Geng CY,Wang HJ,Chen WM

    更新日期:2019-12-14 00:00:00

  • Intracerebroventricular administration of nerve growth factor induces gliogenesis in sensory ganglia, dorsal root, and within the dorsal root entry zone.

    abstract::Previous studies indicated that intracerebroventricular administration of nerve growth factor (NGF) leads to massive Schwann cell hyperplasia surrounding the medulla oblongata and spinal cord. This study was designed to characterize the proliferation of peripheral glial cells, that is, Schwann and satellite cells, in ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/704259

    authors: Schlachetzki JC,Pizzo DP,Morrissette DA,Winkler J

    更新日期:2014-01-01 00:00:00

  • Chronic traumatic encephalopathy and suicide: a systematic review.

    abstract::Traumatic brain injury (TBI) is a global health concern, and the recent literature reports that a single mild TBI can result in chronic traumatic encephalopathy (CTE). It has been suggested that CTE may lead to death by suicide, raising important prevention, treatment, and policy implications. Thus, we conducted a sys...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1155/2013/424280

    authors: Wortzel HS,Shura RD,Brenner LA

    更新日期:2013-01-01 00:00:00

  • Genome-Wide Identification of Putative MicroRNAs in Cassava (Manihot esculenta Crantz) and Their Functional Landscape in Cellular Regulation.

    abstract::MicroRNAs are small noncoding RNAs, involved in the regulation of many cellular processes in plants. Hundreds of miRNAs have been identified in cassava by various techniques, yet these identifications were constrained by a lack of miRNA templates and the narrow range of conditions in transcriptome study. In this resea...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/2019846

    authors: Yawichai A,Kalapanulak S,Thammarongtham C,Saithong T

    更新日期:2019-06-19 00:00:00

  • Computed Tomography versus Optical Scanning: A Comparison of Different Methods of 3D Data Acquisition for Tooth Replication.

    abstract:Objectives:The study aimed to compare the accuracy of different methods of data acquisition and data reconstruction and to assess their usefulness for 3D printing of tooth replicas. Methods:3-dimensional models of molar and canine teeth obtain utilizing CBCT examination with different protocols, and optical scanning w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4985121

    authors: Kulczyk T,Rychlik M,Lorkiewicz-Muszyńska D,Abreu-Głowacka M,Czajka-Jakubowska A,Przystańska A

    更新日期:2019-04-10 00:00:00

  • Constructing a Genome-Wide LD Map of Wild A. gambiae Using Next-Generation Sequencing.

    abstract::Anopheles gambiae is the major malaria vector in Africa. Examining the molecular basis of A. gambiae traits requires knowledge of both genetic variation and genome-wide linkage disequilibrium (LD) map of wild A. gambiae populations from malaria-endemic areas. We sequenced the genomes of nine wild A. gambiae mosquitoes...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/238139

    authors: Wang X,Afrane YA,Yan G,Li J

    更新日期:2015-01-01 00:00:00

  • Efficacy of Terpenoid in Attenuating Aortic Atherosclerosis in Apolipoprotein-E Deficient Mice: A Meta-Analysis of Animal Studies.

    abstract:Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1155/2019/2931831

    authors: Liu H,Zhang Y,Sun S,Wang S

    更新日期:2019-07-17 00:00:00

  • Reduction in Endometrioma Size with Three Months of Aromatase Inhibition and Progestin Add-Back.

    abstract::The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2015/878517

    authors: Agarwal SK,Foster WG

    更新日期:2015-01-01 00:00:00

  • OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.

    abstract::This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the angiogenesis of HUVECs through miR-210-3p expression and exploring the relationship among miR-210-3p, its target protein, and the possible mechanism of angiogenesis regulation. miR-210-3p expression was detected in OSCC tissues an...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2125656

    authors: Wang H,Wang L,Zhou X,Luo X,Liu K,Jiang E,Chen Y,Shao Z,Shang Z

    更新日期:2020-07-08 00:00:00

  • Contribution of psychological factors in dropping out from chronic obstructive pulmonary disease rehabilitation programs.

    abstract::Significant positive effects, particularly on psychological state in patients who completed the follow-up pulmonary rehabilitation programs, are indicated by a large number of studies. Yet, a remarkable proportion of selected patients drop out from these programs. In this study, we investigated existing differences on...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/401326

    authors: Tselebis A,Kosmas E,Bratis D,Pachi A,Ilias I,Harikiopoulou M,Theodorakopoulou E,Velentzas K,Dumitru S,Moussas G,Siafakas N,Tzanakis N

    更新日期:2014-01-01 00:00:00

  • A Meta-Analysis of Different Types of Cardiac Adipose Tissue in HIV Patients.

    abstract:Background:Antiretroviral therapy transformed HIV infection into a chronic disease but accelerated cardiovascular disease (CVD). Both of epicardial adipose tissue (EAT) and pericardial fat (PCF) have close relationships with CVD. The associations between these two cardiac adipose tissue and HIV are unclear. Methods:El...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/8234618

    authors: Song G,Qiao W,Sun L,Yu X

    更新日期:2020-12-09 00:00:00

  • Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer.

    abstract::The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confi...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/569130

    authors: Prasad VG,Kawade S,Jayashree BS,Reddy ND,Francis A,Nayak PG,Kishore A,Nandakumar K,Rao CM,Shenoy RR

    更新日期:2014-01-01 00:00:00

  • Molecular Modelling and Dynamics Study of nsSNP in STXBP1 Gene in Early Infantile Epileptic Encephalopathy Disease.

    abstract::Early Infantile Epileptic Encephalopathy (known as Ohtahara Syndrome) is one of the most severe and earliest forms of epilepsy, characterized by early seizures onset. It affects newborns and children between two and six years old. Among the genes that have been associated with early infantile epileptic encephalopathy,...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4872101

    authors: Al Mehdi K,Fouad B,Zouhair E,Boutaina B,Yassine N,Chaimaa AEC,Najat S,Hassan R,Rachida R,Abdelhamid B,Halima N

    更新日期:2019-12-17 00:00:00

  • Characterization of a Thioredoxin-1 Gene from Taenia solium and Its Encoding Product.

    abstract::Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/453469

    authors: Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

    更新日期:2015-01-01 00:00:00

  • Impact of MRSA Transmission and Infection in a Neonatal Intensive Care Unit in China: A Bundle Intervention Study during 2014-2017.

    abstract::Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5490413

    authors: Huang H,Ran J,Yang J,Li P,Zhuang G

    更新日期:2019-07-10 00:00:00

  • Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer.

    abstract::Colorectal cancer (CRC) is a common malignancy with high morbidity and mortality worldwide. To date, chemotherapy plays an important role in the treatment of CRC patients. Multidrug resistance (MDR) is one of the major hurdles in chemotherapy for CRC, and the underlying mechanisms need to be explored. Studies have dem...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/9390878

    authors: Yuan S,Tao F,Zhang X,Zhang Y,Sun X,Wu D

    更新日期:2020-03-18 00:00:00

  • Optimized periocular template selection for human recognition.

    abstract::A novel approach for selecting a rectangular template around periocular region optimally potential for human recognition is proposed. A comparatively larger template of periocular image than the optimal one can be slightly more potent for recognition, but the larger template heavily slows down the biometric system by ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/481431

    authors: Bakshi S,Sa PK,Majhi B

    更新日期:2013-01-01 00:00:00

  • Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression.

    abstract::Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved in the initiation ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/539805

    authors: Chen TH,Liu SW,Chen MR,Cho KH,Chen TY,Chu PH,Kao YY,Hsu CH,Lin KM

    更新日期:2015-01-01 00:00:00

  • Misaponin B Induces G2/M Arrest, Cytokinesis Failure and Impairs Autophagy.

    abstract::Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/5925094

    authors: Won G,Jung JH,Sohn EJ,Park JE,Kim H,Lee HJ,Shim BS,Kim SH

    更新日期:2020-02-07 00:00:00

  • Emergency versus Elective Cervical Cerclage: An Audit of Our First Two Years of Service.

    abstract::One of the biggest obstetric challenges is the diagnosis and management of a short cervix as cervical length has an inverse relationship with risk of preterm birth. A cervical cerclage is a surgical procedure to reduce the risk of preterm birth and can be placed in an elective or emergency setting. This is a retrospec...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1155/2018/2065232

    authors: Vasudeva N,Reddington C,Bogdanska M,De Luca L

    更新日期:2018-09-30 00:00:00

  • Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.

    abstract::Cancer cells acquire unique secretome compositions that contribute to tumor development and metastasis. The aim of our study was to elucidate the biological processes involved in cervical cancer, by performing a proteomic analysis of the secretome from the following informative cervical cell lines: SiHa (HPV16+), HeLa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/4180703

    authors: Kontostathi G,Zoidakis J,Makridakis M,Lygirou V,Mermelekas G,Papadopoulos T,Vougas K,Vlamis-Gardikas A,Drakakis P,Loutradis D,Vlahou A,Anagnou NP,Pappa KI

    更新日期:2017-01-01 00:00:00

  • Dynamic Alu methylation during normal development, aging, and tumorigenesis.

    abstract::DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu elements is an impor...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/784706

    authors: Luo Y,Lu X,Xie H

    更新日期:2014-01-01 00:00:00

  • Attitude of Jordanian Physicians toward Biochemistry and Genetics.

    abstract:Background:Several studies found that physicians develop a negative attitude toward biochemistry and genetics disciplines. Many medical schools adopt an integrated system-based curriculum supplemented with clinical correlations. Medical schools in Jordan switched to the integrated curriculum; however, studies that eval...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3176951

    authors: Alfaqih MA,Khader YS,Bashir N,Nusair Z,Nuseir Q,Nusier M

    更新日期:2019-11-13 00:00:00

  • Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound.

    abstract::Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been prop...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/640397

    authors: Eisenbrey JR,Sridharan A,Liu JB,Forsberg F

    更新日期:2015-01-01 00:00:00

  • Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.

    abstract::Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim of this study was to analyze the effect of sodium arsenite (NaAsO2) ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/175025

    authors: Gutiérrez-Torres DS,González-Horta C,Del Razo LM,Infante-Ramírez R,Ramos-Martínez E,Levario-Carrillo M,Sánchez-Ramírez B

    更新日期:2015-01-01 00:00:00

  • Hypertrophic Pachymeningitis in Chinese Patients: Presentation, Radiological Findings, and Clinical Course.

    abstract:Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2926419

    authors: Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

    更新日期:2020-08-14 00:00:00

  • Occupational allergic diseases in kitchen and health care workers: an underestimated health issue.

    abstract:OBJECTIVE:This study evaluated the frequencies of allergic symptoms and rate of upper respiratory infections during the past year in the general population, kitchen workers (KW) and health care workers (HCW). METHODS:The European Community Respiratory Health Survey (ECRHS) was used to inquire retrospectively about ast...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/285420

    authors: Bilge U,Unluoglu I,Son N,Keskin A,Korkut Y,Unalacak M

    更新日期:2013-01-01 00:00:00

  • Factors Affecting the Foveal Avascular Zone Area in Healthy Eyes among Young Chinese Adults.

    abstract:Purpose:To evaluate the influence of systemic and ocular factors on the foveal avascular zone (FAZ) area in young Chinese subjects' healthy eyes. Methods:The current observational, cross-sectional study included 344 eyes from 172 healthy individuals (103 women, 69 men). Optical coherence tomography angiography realize...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/7361492

    authors: Zhou Y,Zhou M,Gao M,Liu H,Sun X

    更新日期:2020-03-24 00:00:00

  • Odontogenic Abscess-Related Emergency Hospital Admissions: A Retrospective Data Analysis of 120 Children and Young People Requiring Surgical Drainage.

    abstract:Introduction:Even today, despite medical progress and intensive health education, odontogenic infections leading to surgical intervention and hospitalization are common in children and young people. The aim of this study was to give a detailed overview of clinical and economic data on children and young people treated ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/3504727

    authors: Doll C,Carl F,Neumann K,Voss JO,Hartwig S,Waluga R,Heiland M,Raguse JD

    更新日期:2018-08-26 00:00:00