Abstract:
:Effects of ketamine and lidocaine on electroencephalographic (EEG) changes were evaluated in minimally anaesthetized dogs, subjected to electric stimulus. Six dogs were subjected to six treatments in a crossover design with a washout period of one week. Dogs were subjected to intravenous boluses of lidocaine 2 mg/kg, ketamine 3 mg/kg, meloxicam 0.2 mg/kg, morphine 0.2 mg/kg and loading doses of lidocaine 2 mg/kg followed by continuous rate infusion (CRI) of 50 and 100 mcg/kg/min, and ketamine 3 mg/kg followed by CRI of 10 and 50 mcg/kg/min. Electroencephalogram was recorded during electrical stimulation prior to any drug treatment (before treatment) and during electrical stimulation following treatment with the drugs (after treatment) under anaesthesia. Anaesthesia was induced with propofol and maintained with halothane at a stable concentration between 0.85 and 0.95%. Pretreatment median frequency was evidently increased (P < 0.05) for all treatment groups. Lidocaine, ketamine, and morphine depressed the median frequency resulting from the posttreatment stimulation. The depression of median frequency suggested evident antinociceptive effects of these treatments in dogs. It is therefore concluded that lidocaine and ketamine can be used in the analgesic protocol for the postoperative pain management in dogs.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Kaka U,Hui Cheng C,Meng GY,Fakurazi S,Kaka A,Behan AA,Ebrahimi Mdoi
10.1155/2015/305367subject
Has Abstractpub_date
2015-01-01 00:00:00pages
305367eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
杂志文章abstract::Seeking new biomarkers for epithelial ovarian cancer, the fifth most common cause of death from all cancers in women and the leading cause of death from gynaecological malignancies, we performed a meta-analysis of three independent studies and compared the results in regard to clinicopathological parameters. This anal...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2013/238284
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journal_title:BioMed research international
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journal_title:BioMed research international
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pub_type: 杂志文章,评审
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journal_title:BioMed research international
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/8502873
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journal_title:BioMed research international
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2125656
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9404508
更新日期:2018-01-21 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/6871081
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1494157
更新日期:2018-03-12 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/241298
更新日期:2014-01-01 00:00:00
abstract::This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal su...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1042038
更新日期:2018-01-16 00:00:00
abstract::A surface plasmon resonance- (SPR-) based recognition method applying H-2 Ld:Ig/peptides complexes for ex vivo monitoring cellular immune responses during murine infection with Leishmania (Leishmania) amazonensis is described. Lymphocytes from lesion-draining popliteal lymph nodes were captured on a carboxylated senso...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9089748
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/361329
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/258470
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/243162
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5087643
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8697913
更新日期:2018-03-07 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/141526
更新日期:2015-01-01 00:00:00
abstract::Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 patients was carried...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/167196
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To identify an effective method to prevent myopia progression by characterizing the regulation of matrix metalloproteinase- (MMP-) 2 expression and its secretion from scleral fibroblasts and retinal pigment epithelium (RPE) cells by miR-29a. METHODS:The effects of miR-29a on the growth of scleral fibroblasts a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2647879
更新日期:2017-01-01 00:00:00
abstract::Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/4628592
更新日期:2016-01-01 00:00:00
abstract::The present study is designed to determine potential target genes involved in hepatocellular carcinoma (HCC) and provide possible underlying mechanisms of action. Several studies (GSE112790, GSE87630, and GSE56140) from the GEO database looking at molecular characteristics in HCC were screened and analyzed by GEO2R, w...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7042124
更新日期:2020-10-05 00:00:00
abstract::Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/671859
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/695713
更新日期:2014-01-01 00:00:00
abstract:AIM:Cardiac rehabilitation (CR) is an important part of heart failure (HF) treatment. The aim of this paper was to evaluate if thoracic fluid content (TFC) measured by impedance cardiography (ICG) is a useful parameter for predicting the outcome of CR. METHODS:Fifty HF patients underwent clinical and noninvasive haemo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/595369
更新日期:2013-01-01 00:00:00