Electroencephalographic changes associated with antinociceptive actions of lidocaine, ketamine, meloxicam, and morphine administration in minimally anaesthetized dogs.

Abstract:

:Effects of ketamine and lidocaine on electroencephalographic (EEG) changes were evaluated in minimally anaesthetized dogs, subjected to electric stimulus. Six dogs were subjected to six treatments in a crossover design with a washout period of one week. Dogs were subjected to intravenous boluses of lidocaine 2 mg/kg, ketamine 3 mg/kg, meloxicam 0.2 mg/kg, morphine 0.2 mg/kg and loading doses of lidocaine 2 mg/kg followed by continuous rate infusion (CRI) of 50 and 100 mcg/kg/min, and ketamine 3 mg/kg followed by CRI of 10 and 50 mcg/kg/min. Electroencephalogram was recorded during electrical stimulation prior to any drug treatment (before treatment) and during electrical stimulation following treatment with the drugs (after treatment) under anaesthesia. Anaesthesia was induced with propofol and maintained with halothane at a stable concentration between 0.85 and 0.95%. Pretreatment median frequency was evidently increased (P < 0.05) for all treatment groups. Lidocaine, ketamine, and morphine depressed the median frequency resulting from the posttreatment stimulation. The depression of median frequency suggested evident antinociceptive effects of these treatments in dogs. It is therefore concluded that lidocaine and ketamine can be used in the analgesic protocol for the postoperative pain management in dogs.

journal_name

Biomed Res Int

authors

Kaka U,Hui Cheng C,Meng GY,Fakurazi S,Kaka A,Behan AA,Ebrahimi M

doi

10.1155/2015/305367

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

305367

eissn

2314-6133

issn

2314-6141

journal_volume

2015

pub_type

杂志文章
  • Meta-analysis of microarray data identifies GAS6 expression as an independent predictor of poor survival in ovarian cancer.

    abstract::Seeking new biomarkers for epithelial ovarian cancer, the fifth most common cause of death from all cancers in women and the leading cause of death from gynaecological malignancies, we performed a meta-analysis of three independent studies and compared the results in regard to clinicopathological parameters. This anal...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2013/238284

    authors: Buehler M,Tse B,Leboucq A,Jacob F,Caduff R,Fink D,Goldstein DR,Heinzelmann-Schwarz V

    更新日期:2013-01-01 00:00:00

  • Effect of Chronic Kidney Disease on Changes in Vasopressin System Expression in the Kidney Cortex in Rats with Nephrectomy.

    abstract::It is believed that the vasopressinergic system plays an important role in the pathogenesis of chronic kidney disease (CKD). The aim of this study was to evaluate the effect of CKD on changes in vasopressin system expression in the kidney cortex in rats with nephrectomy. The study was performed on 4 groups of Sprague ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/2607928

    authors: Czarzasta K,Cudnoch-Jedrzejewska A,Niemczyk L,Wrzesien R,Tkaczyk M,Puchalska L,Saracyn M,Zmudzki W,Niemczyk S

    更新日期:2018-06-14 00:00:00

  • Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression.

    abstract::Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved in the initiation ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/539805

    authors: Chen TH,Liu SW,Chen MR,Cho KH,Chen TY,Chu PH,Kao YY,Hsu CH,Lin KM

    更新日期:2015-01-01 00:00:00

  • Molecular mechanisms involved in the pathogenesis of alphavirus-induced arthritis.

    abstract::Arthritogenic alphaviruses, including Ross River virus (RRV), Chikungunya virus (CHIKV), Sindbis virus (SINV), Mayaro virus (MAYV), O'nyong-nyong virus (ONNV), and Barmah Forest virus (BFV), cause incapacitating and long lasting articular disease/myalgia. Outbreaks of viral arthritis and the global distribution of the...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/973516

    authors: Assunção-Miranda I,Cruz-Oliveira C,Da Poian AT

    更新日期:2013-01-01 00:00:00

  • Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.

    abstract::Tripartite Motif Containing 11 (TRIM11), an E3 ubiquitin ligase, is identified as a carcinogen causing certain human cancers. However, the specific role of TRIM11 is still uncovered in human osteosarcoma (OS) cells. To explore the role of TRIM11 in OS cells, TRIM11 was induced by silencing and overexpression in OS cel...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/9612125

    authors: Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

    更新日期:2019-12-25 00:00:00

  • Markers of Alzheimer's Disease in Primary Visual Cortex in Normal Aging in Mice.

    abstract::Aging is the principal risk factor for the development of Alzheimer's disease (AD). The hallmarks of AD are accumulation of the amyloid-β peptide 1-42 (Aβ42) and abnormal hyperphosphorylation of Tau (p-Tau) protein in different areas of the brain and, more recently reported, in the visual cortex. Recently, Aβ42 peptid...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/3706018

    authors: Hernández-Zimbrón LF,Perez-Hernández M,Torres-Romero A,Gorostieta-Salas E,Gonzalez-Salinas R,Gulias-Cañizo R,Quiroz-Mercado H,Zenteno E

    更新日期:2017-01-01 00:00:00

  • Enhancing Image Characteristics of Retinal Images of Aggressive Posterior Retinopathy of Prematurity Using a Novel Software, (RetiView).

    abstract::Purpose. To report pilot data from a novel image analysis software "RetiView," to highlight clinically relevant information in RetCam images of infants with aggressive posterior retinopathy of prematurity (APROP). Methods. Twenty-three imaging sessions of consecutive infants of Asian Indian origin with clinically diag...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/898197

    authors: Jayadev C,Vinekar A,Mohanachandra P,Desai S,Suveer A,Mangalesh S,Bauer N,Shetty B

    更新日期:2015-01-01 00:00:00

  • An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall.

    abstract::This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of bl...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8502873

    authors: Zhang Q,Zhang Y,Zhou Y,Zhang K,Zhang K,Gao L

    更新日期:2016-01-01 00:00:00

  • Composition Analysis and Feature Selection of the Oral Microbiota Associated with Periodontal Disease.

    abstract::Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/3130607

    authors: Chen WP,Chang SH,Tang CY,Liou ML,Tsai SJ,Lin YL

    更新日期:2018-11-15 00:00:00

  • Effects of Selenium on Differentiation and Antioxidant Activity of Sclerotium of Penicillium thomii Q1 Strain.

    abstract::Selenium is an essential trace element, which has certain antioxidant properties. Na2SeO3 is toxic, and its use is limited. SeMet, as an organic selenium, is less toxic than Na2SeO3. In this experiment, different concentrations of Na2SeO3 and SeMet were added to MEA and PDA media to observe the effect of selenium on t...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2368245

    authors: Zhao W,Zhai F,Han J

    更新日期:2020-04-26 00:00:00

  • OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.

    abstract::This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the angiogenesis of HUVECs through miR-210-3p expression and exploring the relationship among miR-210-3p, its target protein, and the possible mechanism of angiogenesis regulation. miR-210-3p expression was detected in OSCC tissues an...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2125656

    authors: Wang H,Wang L,Zhou X,Luo X,Liu K,Jiang E,Chen Y,Shao Z,Shang Z

    更新日期:2020-07-08 00:00:00

  • Inter- and Intraspecific Variations in the Pectoral Muscles of Common Chimpanzees (Pan troglodytes), Bonobos (Pan paniscus), and Humans (Homo sapiens).

    abstract::We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens). We have macroscopically dissected these muscles in six adult Pan troglodytes, ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9404508

    authors: Potau JM,Arias-Martorell J,Bello-Hellegouarch G,Casado A,Pastor JF,de Paz F,Diogo R

    更新日期:2018-01-21 00:00:00

  • Effects of Nitric Oxide on Renal Proximal Tubular Na+ Transport.

    abstract::Nitric oxide (NO) has a wide variety of physiological functions in the kidney. Besides the regulatory effects in intrarenal haemodynamics and glomerular microcirculation, in vivo studies reported the diuretic and natriuretic effects of NO. However, opposite results showing the stimulatory effect of NO on Na+ reabsorpt...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/6871081

    authors: Satoh N,Nakamura M,Suzuki A,Tsukada H,Horita S,Suzuki M,Moriya K,Seki G

    更新日期:2017-01-01 00:00:00

  • Antioxidant Enzyme Activities and Secondary Metabolite Profiling of Oil Palm Seedlings Treated with Combination of NPK Fertilizers Infected with Ganoderma boninense.

    abstract::Oil palm (Elaeis guineensis Jacq) is one of the major sources of edible oil. Reducing the effect of Ganoderma, main cause of basal stem rot (BSR) on oil palm, is the main propose of this study. Understanding the oil palm defense mechanism against Ganoderma infection through monitoring changes in the secondary metaboli...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/1494157

    authors: Sahebi M,Hanafi MM,Mohidin H,Rafii MY,Azizi P,Idris AS,Fariz A,Abiri R,Taheri S,Moradpoor M

    更新日期:2018-03-12 00:00:00

  • Influenza and other respiratory viruses involved in severe acute respiratory disease in northern Italy during the pandemic and postpandemic period (2009-2011).

    abstract::Since 2009 pandemic, international health authorities recommended monitoring severe and complicated cases of respiratory disease, that is, severe acute respiratory infection (SARI) and acute respiratory distress syndrome (ARDS). We evaluated the proportion of SARI/ARDS cases and deaths due to influenza A(H1N1)pdm09 in...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/241298

    authors: Pariani E,Martinelli M,Canuti M,Jazaeri Farsani SM,Oude Munnink BB,Deijs M,Tanzi E,Zanetti A,van der Hoek L,Amendola A

    更新日期:2014-01-01 00:00:00

  • Feasibility of Computational Fluid Dynamics for Evaluating the Intraventricular Hemodynamics in Single Right Ventricle Based on Echocardiographic Images.

    abstract::This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal su...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/1042038

    authors: Chen LJ,Tong ZR,Wang Q,Zhang YQ,Liu JL

    更新日期:2018-01-16 00:00:00

  • Exploring the Association of Surface Plasmon Resonance with Recombinant MHC:Ig Hybrid Protein as a Tool for Detecting T Lymphocytes in Mice Infected with Leishmania (Leishmania) amazonensis.

    abstract::A surface plasmon resonance- (SPR-) based recognition method applying H-2 Ld:Ig/peptides complexes for ex vivo monitoring cellular immune responses during murine infection with Leishmania (Leishmania) amazonensis is described. Lymphocytes from lesion-draining popliteal lymph nodes were captured on a carboxylated senso...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/9089748

    authors: da Silveira-Júnior LS,Souza-Silva F,Pereira BA,Cysne-Finkelstein L,Cavalcanti Júnior GB,Alves CR

    更新日期:2017-01-01 00:00:00

  • 18F-labeling using click cycloadditions.

    abstract::Due to expanding applications of positron emission tomography (PET) there is a demand for developing new techniques to introduce fluorine-18 (t 1/2 = 109.8 min). Considering that most novel PET tracers are sensitive biomolecules and that direct introduction of fluorine-18 often needs harsh conditions, the insertion of...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/361329

    authors: Kettenbach K,Schieferstein H,Ross TL

    更新日期:2014-01-01 00:00:00

  • Newborn first feed and prelacteal feeds in Mansoura, Egypt.

    abstract:BACKGROUND:Prelacteal feed (feeding any other substance before first breastfeeding) appears to be common despite its harmful effects. By definition a child provided with prelacteal feed (PLF) is not exclusively breastfed and PLF has many implications for the success and early initiation of breastfeeding. Objectives. To...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/258470

    authors: El-Gilany AH,Abdel-Hady DM

    更新日期:2014-01-01 00:00:00

  • Proteinquakes in the evolution of influenza virus hemagglutinin (A/H1N1) under opposing migration and vaccination pressures.

    abstract::Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Here we show that, while HA evolution is much more complex than NA evolution, it still shows abrupt punctuation changes linked to punctuation changes of NA. HA exhibits proteinquakes, which resemble earthqua...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/243162

    authors: Phillips JC

    更新日期:2015-01-01 00:00:00

  • Evaluation of the Combined Application of AFP, AFP-L3%, and DCP for Hepatocellular Carcinoma Diagnosis: A Meta-analysis.

    abstract::The role of α-fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular carcinoma (HCC) has been questioned in recent years due to its low sensitivity and specificity. In addition to AFP, several new serum biomarkers, such as lens culinaris agglutinin-reactive fraction of AFP (AFP-L3) and des-gamma-carboxy...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/5087643

    authors: Wang X,Zhang Y,Yang N,He H,Tao X,Kou C,Jiang J

    更新日期:2020-09-17 00:00:00

  • Chronic Unpredictable Mild Stress Causing Cardiac and Thoracic Spinal Cord Electrophysiological Abnormalities May Be Associated with Increased Cardiac Expression of Serotonin and Growth-Associated Protein-43 in Rats.

    abstract:Background:The aim of this study was to investigate the potential mechanisms by which chronic unpredictable mild stress (CMS) might induce cardiovascular disease. Methods:Twenty male Sprague-Dawley rats (weighing 180-250 g) were divided into the CMS group (CMS for 3 weeks) and control group (n = 10/group). Sucrose sol...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8697913

    authors: Liu Z,Liu H,Zeng ZH

    更新日期:2018-03-07 00:00:00

  • Role of the Ubiquitin-Proteasome Systems in the Biology and Virulence of Protozoan Parasites.

    abstract::In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/141526

    authors: Muñoz C,San Francisco J,Gutiérrez B,González J

    更新日期:2015-01-01 00:00:00

  • Schwannoma in the upper limbs.

    abstract::Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 patients was carried...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/167196

    authors: Tang CY,Fung B,Fok M,Zhu J

    更新日期:2013-01-01 00:00:00

  • Regulation of Matrix Metalloproteinase-2 Secretion from Scleral Fibroblasts and Retinal Pigment Epithelial Cells by miR-29a.

    abstract:PURPOSE:To identify an effective method to prevent myopia progression by characterizing the regulation of matrix metalloproteinase- (MMP-) 2 expression and its secretion from scleral fibroblasts and retinal pigment epithelium (RPE) cells by miR-29a. METHODS:The effects of miR-29a on the growth of scleral fibroblasts a...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2647879

    authors: Zhang Y,Hu DN,Zhu Y,Sun H,Gu P,Zhu D,Zhou J

    更新日期:2017-01-01 00:00:00

  • Parallel-SymD: A Parallel Approach to Detect Internal Symmetry in Protein Domains.

    abstract::Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/4628592

    authors: Jha A,Flurchick KM,Bikdash M,Kc DB

    更新日期:2016-01-01 00:00:00

  • Identification of the Sixth Complement Component as Potential Key Genes in Hepatocellular Carcinoma via Bioinformatics Analysis.

    abstract::The present study is designed to determine potential target genes involved in hepatocellular carcinoma (HCC) and provide possible underlying mechanisms of action. Several studies (GSE112790, GSE87630, and GSE56140) from the GEO database looking at molecular characteristics in HCC were screened and analyzed by GEO2R, w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/7042124

    authors: Mu D,Qin F,Li B,Zhou Q

    更新日期:2020-10-05 00:00:00

  • A Comparative Study on Multifactor Dimensionality Reduction Methods for Detecting Gene-Gene Interactions with the Survival Phenotype.

    abstract::Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/671859

    authors: Lee S,Kim Y,Kwon MS,Park T

    更新日期:2015-01-01 00:00:00

  • Microscopic varicocelectomy significantly decreases the sperm DNA fragmentation index in patients with infertility.

    abstract:BACKGROUND:Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/695713

    authors: Kadioglu TC,Aliyev E,Celtik M

    更新日期:2014-01-01 00:00:00

  • The usefulness of impedance cardiography for predicting beneficial effects of cardiac rehabilitation in patients with heart failure.

    abstract:AIM:Cardiac rehabilitation (CR) is an important part of heart failure (HF) treatment. The aim of this paper was to evaluate if thoracic fluid content (TFC) measured by impedance cardiography (ICG) is a useful parameter for predicting the outcome of CR. METHODS:Fifty HF patients underwent clinical and noninvasive haemo...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/595369

    authors: Gielerak G,Krzesiński P,Piotrowicz E,Piotrowicz R

    更新日期:2013-01-01 00:00:00