Microscopic varicocelectomy significantly decreases the sperm DNA fragmentation index in patients with infertility.

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：:Protein phosphorylation is one of the most widespread regulatory mechanisms in eukaryotes. Over the past decade, phosphorylation site prediction has emerged as an important problem in the field of bioinformatics. Here, we report a new method, termed Random Forest-based Phosphosite predictor 2.0 (RF-Phos 2.0), to predi...

journal_title：BioMed research international

authors： Ismail HD,Jones A,Kim JH,Newman RH,Kc DB

更新日期：2016-01-01 00:00:00

abstract：:To investigate white matter (WM) abnormalities in neocortical epilepsy, we extract supratentorial WM parameters from raw tensor magnetic resonance images (MRI) with automated region-of-interest (ROI) registrations. Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched...

journal_title：BioMed research international

authors： Peng SJ,Harnod T,Tsai JZ,Huang CC,Ker MD,Chiou JC,Chiueh H,Wu CY,Hsin YL

更新日期：2014-01-01 00:00:00

abstract：Design:From July 2016 to June 2018, 36 women with symptomatic early pregnancy around 4-8 weeks of gestation were recruited into the study. Among them, there were 16 women with viable intrauterine pregnancy (VIP), 9 women with spontaneous abortion (SA), and 11 women of EP. Serum exosomal miRNAs were extracted and measur...

journal_title：BioMed research international

authors： Sun J,Deng G,Ruan X,Chen S,Liao H,Liu X,Li J,Zhao G,Gao J

更新日期：2020-06-11 00:00:00

abstract：:This study aimed to evaluate the genes that were expressed in the healing bones around SLA-treated titanium orthodontic mini-implants in a beagle at early (1-week) and late (4-week) stages with RNA-sequencing (RNA-Seq). Samples from sites of surgical defects were used as controls. Total RNA was extracted from the tiss...

journal_title：BioMed research international

authors： Nahm KY,Heo JS,Lee JH,Lee DY,Chung KR,Ahn HW,Kim SH

更新日期：2015-01-01 00:00:00

abstract：Objectives:(1) To determine whether manual (MTB), or electric, tooth brushing (ETB) modulates whole salivary flow rate in older adults who are free of systemic disease. (2) To determine the duration of the brushing-related modulation of salivary flow rate. (3) To compare salivary flow rate modulation associated with MT...

journal_title：BioMed research international

authors： Affoo RH,Trottier K,Garrick R,Mascarenhas T,Jang Y,Martin RE

更新日期：2018-02-26 00:00:00

abstract：BACKGROUND:Inflammation has a key role in migraine pathophysiology. Vitamin D is an effective anti-inflammatory agent. The aim of this study was to investigate the association between migraine and two vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and also the relationship between VDR polymorphisms and headache...

journal_title：BioMed research international

authors： Motaghi M,Haghjooy Javanmard S,Haghdoost F,Tajadini M,Saadatnia M,Rafiee L,Zandifar A

更新日期：2013-01-01 00:00:00

abstract：:The anaerobic batch test (45 days at 37°C) was performed to describe the effect of thermal pretreatment at moderate temperatures (60, 80, and 100°C) over durations of 10 and 20 minutes on the enhancement of biogas production using hotel food waste from city of Jaipur, India. The results showed that the total cumulativ...

journal_title：BioMed research international

authors： Gandhi P,Paritosh K,Pareek N,Mathur S,Lizasoain J,Gronauer A,Bauer A,Vivekanand V

更新日期：2018-09-16 00:00:00

abstract：OBJECT:The aim of this report was to explore the clinical presentation, radiological features, treatment methods, and outcome of micro-AVMs presenting with intracerebral hemorrhage. METHODS:The clinical data, radiological features, treatment, and follow-up results for a consecutive series of 13 cases with micro-AVMs w...

journal_title：BioMed research international

authors： Hong JF,Song YF,Liu HB,Liu Z,Wang SS

更新日期：2015-01-01 00:00:00

abstract：:The current developments of the new biological drugs targeting interleukin 5 (IL-5) and IL-5 receptor allowed to expand the treatment options for severe hypereosinophilic asthma. Clinicians will then be able to choose between antibodies targeting either circulating IL-5 or its receptor expressed on eosinophils and bas...

journal_title：BioMed research international

authors： Bagnasco D,Caminati M,Ferrando M,Aloè T,Testino E,Canonica GW,Passalacqua G

更新日期：2018-11-05 00:00:00

abstract：OBJECTIVE:Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditio...

journal_title：BioMed research international

authors： Jacobs JL,Marcus RL,Morrell G,LaStayo P

更新日期：2014-01-01 00:00:00

abstract：:Hydrogel injection has been recently proposed as a novel therapy for disc degenerative diseases, with the potential to restore the spine motion and the intervertebral disc height. However, it remains unknown whether the new technique could also maintain the shock absorbing property of the treated intervertebral disc. ...

journal_title：BioMed research international

authors： Zhou Z,Gao M,Wei F,Liang J,Deng W,Dai X,Zhou G,Zou X

更新日期：2014-01-01 00:00:00

abstract：:N6-methyladenosine (m6A) plays an important role in many cancers. However, few studies have examined the role of m6A in colorectal CRC. To examine the effect of m6A on CRC, we studied the genome of 591 CRC cases from The Cancer Genome Atlas (TCGA). The relationship between the messenger RNA (mRNA) expression, copy num...

journal_title：BioMed research international

authors： Zhang Q,Cai Y,Kurbatov V,Khan SA,Lu L,Zhang Y,Johnson CH

更新日期：2020-12-19 00:00:00

abstract：:We test the hypothesis that ultrasound-targeted microbubble destruction (UTMD) technique increases the renoprotective effect of kidney-targeted transplantation of bone-marrow-derived mesenchymal stem cells (BM-MSCs) in diabetic nephropathy (DN) rats. Diabetes was induced by streptozotocin injection (60 mg/Kg, intraper...

journal_title：BioMed research international

authors： Zhang Y,Ye C,Wang G,Gao Y,Tan K,Zhuo Z,Liu Z,Xia H,Yang D,Li P

更新日期：2013-01-01 00:00:00

abstract：:Energy dispersive X-ray spectroscopy microanalysis (EDX), scanning electron microscopy (SEM), and Archimedes' Principle were used to determine the characteristics of inorganic filler particles in five dental alginates, including Cavex ColorChange (C), Hydrogum 5 (H5), Hydrogum (H), Orthoprint (O), and Jeltrate Plus (J...

journal_title：BioMed research international

authors： Guiraldo RD,Berger SB,Consani RL,Consani S,de Carvalho RV,Lopes MB,Meneghel LL,da Silva FB,Sinhoreti MA

更新日期：2014-01-01 00:00:00

abstract：:With the development of molecular ecology, increasing low-abundance microbial populations were detected in oil reservoirs. However, our knowledge about the oil recovery potential of these populations is lacking. In this study, the oil recovery potential of low-abundance Dietzia that accounts for less than 0.5% in micr...

journal_title：BioMed research international

authors： Gao P,Wang H,Li G,Ma T

更新日期：2019-10-02 00:00:00

abstract：:Diabetes mellitus (DM) is one of the major metabolic disorders that is currently threatening the world. DM is seen associated with obesity and diabetic retinopathy (DR). In the present paper we tried to evaluate the relationship between the three aliments at the gene level and further performed the molecular docking t...

journal_title：BioMed research international

authors： Rampogu S,Rampogu Lemuel M

更新日期：2016-01-01 00:00:00

abstract：:Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...

journal_title：BioMed research international

authors： Wu J,Xia S,Kalionis B,Wan W,Sun T

更新日期：2014-01-01 00:00:00

abstract：Objectives:To evaluate the effects of pentobarbital dosages on lower urinary tract function and to define an appropriate dosage of sodium pentobarbital that would be suitable for urodynamic studies in which recovery from anesthesia and long term survive were needed for subsequent experiment. Methods:Twenty-four 8-week...

journal_title：BioMed research international

authors： Xu SF,Du GH,Abulikim K,Cao P,Tan HB

更新日期：2020-06-11 00:00:00

abstract：CONTEXT:IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. PATIENTS AND METHODS:We studied 64 ad...

journal_title：BioMed research international

authors： Ribeiro TC,Jorge AA,Almeida MQ,Mariani BM,Nishi MY,Mendonca BB,Fragoso MC,Latronico AC

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Previous studies have demonstrated the safety and efficacy of using Paricalcitol for the treatment of secondary hyperparathyroidism (SHPT) in patients on dialysis. The aim of the current meta-analysis was to assess the safety and efficacy of Paricalcitol for the management of SHPT in patients with chronic ...

journal_title：BioMed research international

authors： Han T,Rong G,Quan D,Shu Y,Liang Z,She N,Liu M,Yang B,Cheng G,Lv Y,Stern L

更新日期：2013-01-01 00:00:00

abstract：:A prospective nonrandomized controlled study was conducted to explore the association between ocular dominance and degree of myopia in patients with anisometropia and to investigate the character of visual evoked potential (VEP) in high anisometropias. 1771 young myopia cases including 790 anisometropias were recruite...

journal_title：BioMed research international

authors： Wang Q,Wu Y,Liu W,Gao L

更新日期：2016-01-01 00:00:00

abstract：:Although considerable progress has been made in the management of patients with invasive fungal infections, Candida bloodstream infections are still widespread in hospital settings. Incidence rates vary geographically, often because of different patient populations. The aim of the present study was to describe the epi...

journal_title：BioMed research international

authors： Caggiano G,Coretti C,Bartolomeo N,Lovero G,De Giglio O,Montagna MT

更新日期：2015-01-01 00:00:00

abstract：:Actin is one of the most highly conserved proteins and plays crucial roles in many vital cellular functions. In most eukaryotes, it is encoded by a multigene family. Although the actin gene family has been studied a lot, few investigators focus on the comparison of actin gene family in relative species. Here, the purp...

journal_title：BioMed research international

authors： Zhu L,Zhang Y,Hu Y,Wen T,Wang Q

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cost sharing between beneficiaries and government is critical to attain universal health coverage. The government of Ethiopia introduced social health insurance to improve access to quality health services. Hence, HCP are the ultimate frontline service provider; their WTP for health insurance could influence...

journal_title：BioMed research international

authors： Mekonne A,Seifu B,Hailu C,Atomsa A

更新日期：2020-04-14 00:00:00

abstract：:Glioma of infiltrative nature is challenging for surgeons to achieve tumor-specific and maximal resection. Raman spectroscopy provides structural information on the targeted materials as vibrational shifts. We utilized Raman spectroscopy to distinguish invasive tumors from normal tissues. Spectra obtained from replica...

journal_title：BioMed research international

authors： Tanahashi K,Natsume A,Ohka F,Momota H,Kato A,Motomura K,Watabe N,Muraishi S,Nakahara H,Saito Y,Takeuchi I,Wakabayashi T

更新日期：2014-01-01 00:00:00

abstract：:Presynaptic and postsynaptic neurotoxins are proteins which act at the presynaptic and postsynaptic membrane. Correctly predicting presynaptic and postsynaptic neurotoxins will provide important clues for drug-target discovery and drug design. In this study, we developed a theoretical method to discriminate presynapti...

journal_title：BioMed research international

authors： Tang H,Yang Y,Zhang C,Chen R,Huang P,Duan C,Zou P

更新日期：2017-01-01 00:00:00

abstract：:Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...

journal_title：BioMed research international

authors： Caimmi M,Guanziroli E,Malosio M,Pedrocchi N,Vicentini F,Molinari Tosatti L,Molteni F

更新日期：2015-01-01 00:00:00

abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

journal_title：BioMed research international

authors： Martínez MJ,Razuc M,Ponzoni I

更新日期：2019-02-17 00:00:00

abstract：:Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and a major cause of nonrelapse mortality after allo-HSCT. A conditioning regimen plays a pivotal role in the development of aGVHD. To provide a platform for studying aGVHD and evaluating t...

journal_title：BioMed research international

authors： He X,Ye Y,Xu X,Wang J,Huang Y,Weng G,Zhang M,Guo K

更新日期：2016-01-01 00:00:00