Conditioning with Fludarabine-Busulfan versus Busulfan-Cyclophosphamide Is Associated with Lower aGVHD and Higher Survival but More Extensive and Long Standing Bone Marrow Damage.

abstract：:Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...

journal_title：BioMed research international

authors： Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé A

更新日期：2016-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00

abstract：:Magnetic resonance imaging (MRI) based on the ferritin heavy chain 1 (FTH1) reporter gene has been used to trace stem cells. However, whether FTH1 expression is affected by stem cell differentiation or whether cell differentiation is affected by reporter gene expression remains unclear. Here, we explore the relationsh...

journal_title：BioMed research international

authors： Mu T,Qin Y,Liu B,He X,Liao Y,Sun J,Qiu J,Li X,Zhong Y,Cai J

更新日期：2018-06-26 00:00:00

abstract：Objective:We compared the prostate cancer (PCa) detection rates of targeted biopsy (TB) and saturation biopsy (SB) in patients with previous negative biopsy and the accuracy of TB and SB stratified by different serum prostate-specific antigen (PSA) levels. Materials and Methods:Overall 185 patients were enrolled. In t...

journal_title：BioMed research international

authors： Chang CH,Chiu HC,Lin WC,Ho TL,Chang H,Chang YH,Huang CP,Wu HC,Yang CR,Hsieh PF

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The presence of common risk factors suggests that there is a relationship between osteoporosis and cardiovascular disease, possibly via dyslipidemia and inflammation. We investigated the relationships among the lipid profile, the inflammation marker high-sensitivity C-reactive protein (hsCRP), bone turnover ...

journal_title：BioMed research international

authors： Jeong TD,Lee W,Choi SE,Kim JS,Kim HK,Bae SJ,Chun S,Min WK

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone destruction in RA. Ho...

journal_title：BioMed research international

authors： Song J,Liu H,Zhu Q,Miao Y,Wang F,Yang F,Cheng W,Xi Y,Niu X,He D,Chen G

更新日期：2018-02-19 00:00:00

abstract：:Tumors and wounds share many similarities including loss of tissue architecture, cell polarity and cell differentiation, aberrant extracellular matrix (ECM) remodeling (Ballard et al., 2006) increased inflammation, angiogenesis, and elevated cell migration and proliferation. Whereas these changes are transient in repa...

journal_title：BioMed research international

authors： Tolg C,McCarthy JB,Yazdani A,Turley EA

更新日期：2014-01-01 00:00:00

abstract：:This prospective randomized study is to evaluate the locoregional failure and its impact on survival by comparing involved field radiotherapy (IFRT) with elective nodal irradiation (ENI) in combination with concurrent chemotherapy for locally advanced non-small cell lung cancer. It appears that higher dose could be de...

journal_title：BioMed research international

authors： Chen M,Bao Y,Ma HL,Hu X,Wang J,Wang Y,Peng F,Zhou QC,Xie CH

更新日期：2013-01-01 00:00:00

abstract：:cir-ITCH, a well-known tumor-suppressive circular RNA, plays a critical role in different cancers. However, its expression and functional role in prostate cancer (PCa) are unclear. Herein, we explored the potential mechanism and tumor-inhibiting role of cir-ITCH in PCa. Using reverse transcriptase polymerase chain rea...

journal_title：BioMed research international

authors： Li S,Yu C,Zhang Y,Liu J,Jia Y,Sun F,Zhang P,Li J,Guo L,Xiao H,Gao F,Deng X,Cai Z,Cai J

更新日期：2020-08-20 00:00:00

abstract：:The increasing insect resistance against Bacillus thuringiensis delta-endotoxins is a serious problem which makes it urgent to look for new eco-friendly strategies. Combining these toxins with other biomolecules is one of the promising strategies against insect pests. In this work, we evaluated the bioinsecticidal pot...

journal_title：BioMed research international

authors： Mhalla D,Ben Farhat-Touzri D,Tounsi S,Trigui M

更新日期：2018-08-08 00:00:00

abstract：:Toxoplasma gondii with worldwide distribution has received substantial medical and scientific attentions as it causes serious clinical and veterinary problems especially for pregnant women and immunocompromised patients. Heat shock protein 40 (HSP40) plays a variety of essential roles in the pathogenesis of this proto...

journal_title：BioMed research international

authors： Li ZY,Lu J,Zhou DH,Chen J,Zhu XQ

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h...

journal_title：BioMed research international

authors： Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MR

更新日期：2014-01-01 00:00:00

abstract：:Tobacco smoking continues to be a leading cause of disease and mortality. Recent research has confirmed the important role of nicotinic acetylcholine receptor (nAChR) gene cluster on chromosome 15q 24-25 in nicotine dependence and smoking. In this study we tested the association of smoking initiation, age at onset of ...

journal_title：BioMed research international

authors： Buczkowski K,Sieminska A,Linkowska K,Czachowski S,Przybylski G,Jassem E,Grzybowski T

更新日期：2015-01-01 00:00:00

abstract：:Acute leukemias are the most frequent childhood malignancies worldwide and remain a leading cause of morbidity and mortality of relapsed patients. While remarkable progress has been made in characterizing genetic aberrations that may control these hematological disorders, it has also become clear that abnormalities in...

journal_title：BioMed research international

authors： Dorantes-Acosta E,Vadillo E,Contreras-Quiroz A,Balandrán JC,Arriaga-Pizano L,Purizaca J,Huerta-Yepez S,Jiménez E,Aguilera W,Medina-Sanson A,Mayani H,Pelayo R

更新日期：2013-01-01 00:00:00

abstract：:Alzheimer's disease affects millions of people worldwide and incidence is expected to rise as the population ages, but no effective therapies exist despite decades of research and more than 20 known disease markers. Research has shown that Alzheimer's disease's missing heritability remains extensive with an estimated ...

journal_title：BioMed research international

authors： Ebbert MT,Ridge PG,Kauwe JS

更新日期：2015-01-01 00:00:00

abstract：Introduction:We investigated the proportion of myeloid-derived suppressor cells (MDSCs) and their subsets in patients with rheumatic diseases and clarified the association between these cells and the patient clinical data. Methods:Patients with rheumatic diseases and healthy controls were recruited. The clinical chara...

journal_title：BioMed research international

authors： Zhu J,Chen S,Wu L,Wang R,Zheng S,Zhao D,Wang X,Li J

更新日期：2018-06-26 00:00:00

abstract：:Objective. This study aims to extract motor ingredients through data mining from wearable sensors in a virtual reality goal-directed shoulder rehabilitation (GDSR) system and to examine their effects toward clinical assessment. Design. A single-group before/after comparison. Setting. Outpatient research hospital. Subj...

journal_title：BioMed research international

authors： Lee SH,Yeh SC,Chan RC,Chen S,Yang G,Zheng LR

更新日期：2016-01-01 00:00:00

abstract：Background:Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ALCF) is a complicated syndrome with extremely high short-term mortality. The artificial liver support system (ALSS) may improve the liver function for patients with HBV-ACLF, but the data on its short-term outcomes are insufficient in China. ...

journal_title：BioMed research international

authors： Xiao LL,Xu XW,Huang KZ,Zhao YL,Zhang LJ,Li LJ

更新日期：2019-11-29 00:00:00

abstract：:Schistosomiasis, caused by infection with Schistosoma species, remains an important parasitic zoonosis. Thioredoxin glutathione reductase of Schistosoma japonicum (SjTGR) plays an important role in the development of the parasite and for its survival. Here we present a recombinant plasmid DNA vaccine, pVAX1/SjTGR, to ...

journal_title：BioMed research international

authors： Cao Y,Zhao B,Han Y,Zhang J,Li X,Qiu C,Wu X,Hong Y,Ai D,Lin J,Fu Z

更新日期：2013-01-01 00:00:00

abstract：:Background. Antitumor necrosis factor (anti-TNF) drugs have been applied for rheumatoid arthritis (RA) treatment; however, patients having anti-drug antibodies (ADAbs) do not benefit from these drugs. The meta-analysis aims to comprehensively assess the relationship between ADAb positive (ADAb+) and anti-TNF response ...

journal_title：BioMed research international

authors： Wu C,Wang S,Xian P,Yang L,Chen Y,Mo X

更新日期：2016-01-01 00:00:00

abstract：:Retinoblastoma protein (pRB) interacts with E2F and other protein factors to play a pivotal role in regulating the expression of target genes that induce cell cycle arrest, apoptosis, and differentiation. pRB controls the local promoter activity and has the ability to change the structure of nucleosomes and/or chromos...

journal_title：BioMed research international

authors： Uchida C

更新日期：2016-01-01 00:00:00

abstract：:Trichoderma spp. are important biocontrol filamentous fungi, which are widely used for their adaptability, broad antimicrobial spectrum, and various antagonistic mechanisms. In our previous studies, we cloned thga1 gene encoding GαI protein from Trichoderma harzianum Th-33. Its knockout mutant showed that the growth r...

journal_title：BioMed research international

authors： Sun Q,Jiang X,Pang L,Wang L,Li M

更新日期：2016-01-01 00:00:00

abstract：:Pathological studies have shown an association between psoriasis and renal injury (RI), but the mechanism between RI and psoriasis was still unclear. This paper was designed to investigate the relationship and mechanism between psoriasis-like inflammation and renal injury in BALB/C mice. Mice were topically smeared im...

journal_title：BioMed research international

authors： Ren F,Zhang M,Zhang C,Sang H

更新日期：2020-01-21 00:00:00

abstract：PURPOSE:Thermographic assessment of temperature distribution within the examined tissues allows a quick, noncontact, noninvasive measurement of their temperature. The aim of the study was to evaluate the usefulness of digital infrared imaging in monitoring experimental inflammation of pleura (PL), lower lip (LL), and l...

journal_title：BioMed research international

authors： Całkosiński I,Dobrzyński M,Rosińczuk J,Dudek K,Chrószcz A,Fita K,Dymarek R

更新日期：2015-01-01 00:00:00

abstract：:Different opinions exist on the relationship between the C-reactive protein-to-albumin ratio (CAR) and the prognosis of colon cancer. This study is aimed at evaluating the relationship between CAR and prognosis of stage II-III colon cancer and establishing a clinical prognosis model. Patients were randomised to a trai...

journal_title：BioMed research international

authors： Xu Y,Liang F,Chen Y,Wang Z,Zhong H,Tang W

更新日期：2020-11-22 00:00:00

abstract：:Human dental pulp stem cells (DPSCs) hold great promise in bone regeneration. However, the exact mechanism of osteogenic differentiation of DPSCs remains unknown, especially the role of exosomes played in. The DPSCs were cultured and received osteogenic induction; then, exosomes from osteogenic-induced DPSCs (OI-DPSC-...

journal_title：BioMed research international

authors： Xie L,Guan Z,Zhang M,Lyu S,Thuaksuban N,Kamolmattayakul S,Nuntanaranont T

更新日期：2020-09-28 00:00:00

abstract：Background and Aim:ROHHADNET (rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, neuroendocrine tumor) syndrome is a rare disease with grave outcome. Although early recognition is essential, prompt diagnosis may be challenging due to its extreme rarity. This study aimed to systematically r...

journal_title：BioMed research international

authors： Lee JM,Shin J,Kim S,Gee HY,Lee JS,Cha DH,Rim JH,Park SJ,Kim JH,Uçar A,Kronbichler A,Lee KH,Shin JI

更新日期：2018-11-21 00:00:00

abstract：Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

journal_title：BioMed research international

authors： Liu H,Zhang Y,Sun S,Wang S

更新日期：2019-07-17 00:00:00

abstract：Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

journal_title：BioMed research international

authors： Jin X,Niu Y,Gu W,Wang J

更新日期：2020-08-10 00:00:00

abstract：Objective:Delays in skeletal maturity are related to bone mass and fracture risk in children, but the factors that determine it are unknown. We aimed to identify the association between insulin-like growth factor-1 (IGF-1) and skeletal maturation before and after growth hormone (GH) treatment. Methods:In this retrospe...

journal_title：BioMed research international

authors： Zhao Q,Zhang M,Chu Y,Ji B,Pan H,Sun H,Ban B

更新日期：2020-08-13 00:00:00