Central Systolic Hypertension in Patients with Well-Controlled Hypertension.

abstract：:The aim of this study is to investigate the stress distributions of different restoration options for class II mesio-occluso-distal (MOD) cavities. A class II MOD cavity with proximal box gingival floor 1 mm below cementoenamel junction was designed in a mandibular first molar tooth model. 3D finite-element analysis (...

journal_title：BioMed research international

authors： Alp Ş,Gulec Alagoz L,Ulusoy N

更新日期：2020-12-15 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：:Porcine circovirus virus type II (PCV2) is the etiology of postweaning multisystemic wasting syndrome (PMWS), porcine dermatitis, nephropathy syndrome (PDNS), and necrotizing pneumonia. Rapid diagnosis tool for detection of PCV2 plays an important role in the disease control and eradication program. Recombinase polyme...

journal_title：BioMed research international

authors： Yang Y,Qin X,Sun Y,Cong G,Li Y,Zhang Z

更新日期：2017-01-01 00:00:00

abstract：:Tissue regeneration has become a promising treatment for craniomaxillofacial bone defects such as alveolar clefts. This study sought to assess the efficacy of lateral ramus cortical plate with buccal fat pad derived mesenchymal stem cells (BFSCs) in treatment of human alveolar cleft defects. Ten patients with unilater...

journal_title：BioMed research international

authors： Khojasteh A,Kheiri L,Behnia H,Tehranchi A,Nazeman P,Nadjmi N,Soleimani M

更新日期：2017-01-01 00:00:00

abstract：:In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

journal_title：BioMed research international

authors： Muñoz C,San Francisco J,Gutiérrez B,González J

更新日期：2015-01-01 00:00:00

abstract：:The Janus Kinases (JAKs) are a family of intracellular tyrosine kinases that provide transmission signals from cytokine, interferons, and many hormones receptors to the nucleus resulting in synthesis of many biologically active compounds and changing cell metabolism and function. That was theoretical background to syn...

journal_title：BioMed research international

authors： Kotyla PJ

更新日期：2018-05-10 00:00:00

abstract：:New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full-fledged annotation systems are usually home-grown and customized to a particular geno...

journal_title：BioMed research international

authors： Alioto T,Picardi E,Guigó R,Pesole G

更新日期：2013-01-01 00:00:00

abstract：:Ultrasound tomography (UST) image segmentation is fundamental in breast density estimation, medicine response analysis, and anatomical change quantification. Existing methods are time consuming and require massive manual interaction. To address these issues, an automatic algorithm based on GrabCut (AUGC) is proposed i...

journal_title：BioMed research international

authors： Wu S,Yu S,Zhuang L,Wei X,Sak M,Duric N,Hu J,Xie Y

更新日期：2017-01-01 00:00:00

abstract：:We aim to investigate the effects of curcumin on preventing diabetes-induced vascular inflammation in association with its actions on Txnip, ICAM-1, and NOX2 enzyme expressions. Male Wistar rats were divided into four groups: control (CON), diabetic (DM; streptozotocin (STZ), i.v. 55 mg/kg BW), control-treated with cu...

journal_title：BioMed research international

authors： Wongeakin N,Bhattarakosol P,Patumraj S

更新日期：2014-01-01 00:00:00

abstract：:Mexico has one of the highest incidences of childhood leukemia worldwide and significantly higher mortality rates for this disease compared with other countries. One possible cause is the high prevalence of gene rearrangements associated with the etiology or with a poor prognosis of childhood acute lymphoblastic leuke...

journal_title：BioMed research international

authors： Bekker-Méndez VC,Miranda-Peralta E,Núñez-Enríquez JC,Olarte-Carrillo I,Guerra-Castillo FX,Pompa-Mera EN,Ocaña-Mondragón A,Rangel-López A,Bernáldez-Ríos R,Medina-Sanson A,Jiménez-Hernández E,Amador-Sánchez R,Peñaloza-González JG,

更新日期：2014-01-01 00:00:00

abstract：:Objective. To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 -...

journal_title：BioMed research international

authors： Ruiz-Padilla AJ,Gamez-Nava JI,Saldaña-Cruz AM,Murillo-Vazquez JD,Vazquez-Villegas ML,Zavaleta-Muñiz SA,Martín-Márquez BT,Ponce-Guarneros JM,Rodriguez Jimenez NA,Flores-Chavez A,Sandoval-Garcia F,Vasquez-Jimenez JC,Cardona-Muñoz E

更新日期：2016-01-01 00:00:00

abstract：:Probiotic Lactobacillus casei Shirota (LcS) is a potential decontaminating agent of aflatoxin B1 (AFB1). However, few studies have investigated the influence of diet, especially a high protein (HP) diet, on the binding of AFB1 by probiotics. This research was conducted to determine the effect of HP diet on the ability...

journal_title：BioMed research international

authors： Nurul Adilah Z,Liew WP,Mohd Redzwan S,Amin I

更新日期：2018-05-23 00:00:00

abstract：:As the fifth most common cancer in men and the eighth most common cancer in women, hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, with standard chemotherapy and radiation being minimally effective in prolonging survival. Virus hepatitis, particularly HBV and HCV infection is th...

journal_title：BioMed research international

authors： Wang Z,Jin W,Jin H,Wang X

更新日期：2014-01-01 00:00:00

abstract：:Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, including the precis...

journal_title：BioMed research international

authors： Čulen M,Tuszyński PK,Polak S,Jachowicz R,Mendyk A,Dohnal J

更新日期：2015-01-01 00:00:00

abstract：:In the last decade the number of wireless devices operating at the frequency band of 2.4 GHz has increased in several settings, such as healthcare, occupational, and household. In this work, the emissions from Wi-Fi transceivers applicable to context aware scenarios are analyzed in terms of potential interference and ...

journal_title：BioMed research international

authors： de Miguel-Bilbao S,Aguirre E,Lopez Iturri P,Azpilicueta L,Roldán J,Falcone F,Ramos V

更新日期：2015-01-01 00:00:00

abstract：:Asthma susceptibility genes are mapped to a region on human chromosome 5q31-q33, which contains a cluster of proinflammatory cytokine genes such as interleukin-13 (IL-13), which is associated with asthma. This study investigated the allele frequencies of two single nucleotide polymorphisms (SNPs) (-1111C>T and 4257C>A...

journal_title：BioMed research international

authors： Radhakrishnan AK,Raj VL,Tan LK,Liam CK

更新日期：2013-01-01 00:00:00

abstract：:Recent reports of retinal stem cells being present in several locations of the adult eye have sparked great hopes that they may be used to treat the millions of people worldwide who suffer from blindness as a result of retinal disease or injury. A population of proliferative cells derived from the ciliary body epithel...

journal_title：BioMed research international

authors： Frøen R,Johnsen EO,Nicolaissen B,Facskó A,Petrovski G,Moe MC

更新日期：2013-01-01 00:00:00

abstract：Background and Aims:The present study aimed to develop a simple and sensitive method for quantitative determination of monocrotaline (MCT) in mouse blood employing ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI/MS/MS) using rhynchophylline as an internal standard. Me...

journal_title：BioMed research international

authors： Chen L,Zhang B,Liu J,Fan Z,Weng Z,Geng P,Wang X,Lin G

更新日期：2018-08-13 00:00:00

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：:Exosomal miRNAs are currently being explored as a novel class of biomarkers in cardiovascular diseases. However, few reports have focused on the value of circulating exosomal miRNAs as biomarkers for stable coronary artery disease (SCAD). Here, we aimed to investigate whether miRNAs involved in cardiovascular diseases...

journal_title：BioMed research international

authors： Zhang P,Liang T,Chen Y,Wang X,Wu T,Xie Z,Luo J,Yu Y,Yu H

更新日期：2020-12-11 00:00:00

abstract：Objective:This study aims to (i) translate, culturally adapt, and preliminarily validate the arrhythmia-specific Umea22 (U22) questionnaire and (ii) assess the impact of radiofrequency (RF) ablation and medical treatment on the quality of life of patients with supraventricular tachycardias (SVTs). Methods:A total of 1...

journal_title：BioMed research international

authors： Domeyer PR,Giannakidou SC,Kyriakou P,Katsari V,Antoniadis AP,Lagos IK,Fragakis N,Varaklioti A,Vassilikos VP

更新日期：2018-10-09 00:00:00

abstract：:Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn disease (CD). Similar symptoms, but different treatment procedures for both diseases require precise diagnosis. MicroRNAs (miRNAs) are major posttranscriptional players that regulate the expression of genes during the inflammation and thus co...

journal_title：BioMed research international

authors： Guz M,Dworzański T,Jeleniewicz W,Cybulski M,Kozicka J,Stepulak A,Celiński K

更新日期：2020-07-22 00:00:00

abstract：Background:The present study aims to investigate the incidence and risk factors associated with postoperative delirium in patients undergoing spine surgery. Methods:PubMed, EMBASE, Cochrane Library, and Science Citation Index were searched up to August 2019 for studies examining postoperative delirium following spine ...

journal_title：BioMed research international

authors： Wu X,Sun W,Tan M

更新日期：2019-11-26 00:00:00

abstract：:The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or indirectly contribute to NAFLD, especially fatty acid accumulation, arachidonic acid metabolic disturbance, and ceramide overload. The effects o...

journal_title：BioMed research international

authors： Pei K,Gui T,Kan D,Feng H,Jin Y,Yang Y,Zhang Q,Du Z,Gai Z,Wu J,Li Y

更新日期：2020-07-18 00:00:00

abstract：Background:Musculoskeletal disorders (MSDs) are considered one of the most common health issues in working population and have a high social and economic impact. This study is aimed at determining the MSD patterns and associated risk factors among higher education academicians in Saudi Arabia. Methods:A cross-sectiona...

journal_title：BioMed research international

authors： Algarni FS,Kachanathu SJ,AlAbdulwahab SS

更新日期：2020-08-15 00:00:00

abstract：:No pharmacological treatment is currently available to protect brain from neuronal damage after ischemic stroke. Recent studies found that enkephalin may play an important role in neuron regeneration. We assembled a homogeneous size vesicle constituted by transferrin, exosomes, and enkephalin. Immunofluorescence assay...

journal_title：BioMed research international

authors： Liu Y,Fu N,Su J,Wang X,Li X

更新日期：2019-03-04 00:00:00

abstract：:Nitric oxide (NO) has a wide variety of physiological functions in the kidney. Besides the regulatory effects in intrarenal haemodynamics and glomerular microcirculation, in vivo studies reported the diuretic and natriuretic effects of NO. However, opposite results showing the stimulatory effect of NO on Na+ reabsorpt...

journal_title：BioMed research international

authors： Satoh N,Nakamura M,Suzuki A,Tsukada H,Horita S,Suzuki M,Moriya K,Seki G

更新日期：2017-01-01 00:00:00

abstract：:This study evaluated the potential relationship between exosomal miRNAs and clinical symptoms in patients with multiple myeloma (MM). Forty-eight newly diagnosed myeloma patients and sixteen normal donors were enrolled in the study. The results showed that the relative expression levels of let-7c-5p, let-7d-5p, miR-14...

journal_title：BioMed research international

authors： Zhang ZY,Li YC,Geng CY,Wang HJ,Chen WM

更新日期：2019-12-14 00:00:00

abstract：:Canine inflammatory mammary cancer (IMC) shares clinical and histopathological characteristics with human inflammatory breast cancer (IBC) and has been proposed as a good model for studying the human disease. The aim of this study was to evaluate the capacity of female and male mice to reproduce IMC and IBC tumors and...

journal_title：BioMed research international

authors： Caceres S,Peña L,Silvan G,Illera MJ,Woodward WA,Reuben JM,Illera JC

更新日期：2016-01-01 00:00:00

abstract：:Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM) characterized by clonal bone marrow plasma cells (BMPC) ≥ 10% and/or M protein level ≥ 30 g/L in the absence of end organ damage. It represents an intermediate stage between monoclonal gammopathy of undetermined significance ...

journal_title：BioMed research international

authors： Gao M,Yang G,Kong Y,Wu X,Shi J

更新日期：2015-01-01 00:00:00