Abstract:
Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the reconstruction of fingertips injuries. Methods:The cadaveric study involving 8 hands was conducted to illuminate the anatomy of the hypothenar region. We investigated the emerging point of perforators, diameter of the artery at the origin, and the length of the pedicle. Forty-four patients with fingertip injuries underwent fingertip reconstruction using PUAP free flaps. Data on the baseline patient demographics, hospital courses, and flap sizes were obtained retrospectively. The 6-month postoperative sensory capacity was determined using a 2-point discrimination test. Results:The cadaveric study found that the PUAP pedicles arose from the superficial palmar arch, the mean length of pedicles, and the diameter and location of perforators were also analyzed. The PUAP flap sizes varied from 2.0 × 2.3 cm to 2.5 × 3.5 cm, and the mean operative time was 124 min. In all cases, we performed neurorrhaphy for fingertip sensory restoration. All donor sites were closed primarily, and the 2-point discrimination test result was 5.7 ± 0.87 mm 6 months after surgery. Conclusions:We confirmed the anatomical consistency of the PUAP. Among the numerous reconstruction options available for fingertip injuries, the PUAP free flap is a useful fingertip reconstruction option.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Pak CS,Jeon JI,Myung Y,Lee YK,Kim BJ,Jeong JH,Kim BKdoi
10.1155/2018/2862879subject
Has Abstractpub_date
2018-05-09 00:00:00pages
2862879eissn
2314-6133issn
2314-6141journal_volume
2018pub_type
杂志文章abstract:Background:Recurrent shoulder dislocations occur much more frequently in adolescents than in the older population but a clear explanation of this incidence does not exist. The aim of the present study was to define the age-related distribution of the elastic fibers (EFs) in the shoulder capsule's extracellular matrix a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8961805
更新日期:2018-07-18 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/915172
更新日期:2014-01-01 00:00:00
abstract::Alzheimer's disease (AD) and multiple sclerosis are major neurodegenerative diseases, which are characterized by the accumulation of abnormal pathogenic proteins due to oxidative stress, mitochondrial dysfunction, impaired autophagy, and pathogens, leading to neurodegeneration and behavioral deficits. Herein, we revie...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/1483791
更新日期:2018-07-12 00:00:00
abstract::This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the fi...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2016/8357621
更新日期:2016-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2015/714230.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
doi:10.1155/2016/9325260
更新日期:2016-01-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths in Taiwan. CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis. We investigated the CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors related to H...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/231474
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). METHODS:Functional reannotation for the human lncRNA was carried out by ncFANs. Real-time quantitative PCR was used to v...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/405860
更新日期:2014-01-01 00:00:00
abstract::The zebrafish constitutes a powerful model organism with unique advantages for investigating the vertebrate circadian timing system and its regulation by light. In particular, the remarkably early and rapid development of the zebrafish circadian system has facilitated exploring the factors that control the onset of ci...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/235781
更新日期:2014-01-01 00:00:00
abstract::Bacterial quorum sensing (QS) is a cell-to-cell communication in which specific signals are activated to coordinate pathogenic behaviors and help bacteria acclimatize to the disadvantages. The QS signals in the bacteria mainly consist of acyl-homoserine lactone, autoinducing peptide, and autoinducer-2. QS signaling ac...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/2015978
更新日期:2019-04-04 00:00:00
abstract::Among the different signaling molecules released during reactive gliosis occurring in Alzheimer's disease (AD), the astrocyte-derived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease. The use of pharmacological tools targeting S100B may be crucial to embank its effects and some ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/508342
更新日期:2015-01-01 00:00:00
abstract::Ultrasonography has been widely employed to estimate the morphological changes of muscle during contraction. To further investigate the motion pattern of quadriceps during isometric knee extensions, we studied the relative motion pattern between femur and quadriceps under ultrasonography. An interesting observation is...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6385315
更新日期:2018-03-18 00:00:00
abstract::Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/435737
更新日期:2015-01-01 00:00:00
abstract:Objective:This study evaluated the bioactivity and physicochemical properties of three commercial calcium silicate-based endodontic materials (MTA, EndoSequence Root Repair Material putty, and Biodentine™). Material and Methods. Horizontal sections of 3 mm thickness from 18 root canals of human teeth were subjected to ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9576930
更新日期:2020-05-22 00:00:00
abstract::Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Here we show that, while HA evolution is much more complex than NA evolution, it still shows abrupt punctuation changes linked to punctuation changes of NA. HA exhibits proteinquakes, which resemble earthqua...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/243162
更新日期:2015-01-01 00:00:00
abstract::Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Emba...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2017/6274854
更新日期:2017-01-01 00:00:00
abstract::Sericin is a natural protein component of silks of silkworm and has potential utility in multiple areas such as pharmacological, cosmetics, and biotechnological industries. However, the understanding of its toxicological safety is still limited. This study evaluated the safety of water-extract sericin from silkworm (B...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9689386
更新日期:2020-11-05 00:00:00
abstract::Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/3489603
更新日期:2017-01-01 00:00:00
abstract::Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/147196
更新日期:2015-01-01 00:00:00
abstract::Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due to a reduced capacity to vasoconstrict the venous and arterial vessels below the level of the lesion. Exercise training was found to enhance circulating catecholamines and to improve cardiac preload and venous ton...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/893468
更新日期:2014-01-01 00:00:00
abstract::The objective of this study is to introduce a method using a percutaneous full-endoscopic interlaminar approach via a surrounding nerve root discectomy (SNRD) operative route that involves removing the protrusive disc via both the shoulder and the axilla of the corresponding nerve root for the treatment of ventral-typ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/9157089
更新日期:2018-02-12 00:00:00
abstract::Visual motor integration (VMI) is a vital ability in childhood development, which is associated with the performance of many functional skills. By using the Beery Developmental Test Package and Executive Function Tasks, the present study explored the VMI development and its factors (visual perception, motor coordinati...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/6264254
更新日期:2017-01-01 00:00:00
abstract::Post-Kala-Azar Dermal Leishmaniasis (PKDL) remains a major public health threat in Bangladesh. A cross-sectional study was carried out in Surya Kanta Kala azar Research Centre (SKKRC), Mymensingh, from January 2012 to July 2013 to evaluate the health seeking behaviour and the length of delay of PKDL management. The co...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/314543
更新日期:2015-01-01 00:00:00
abstract:Objective:This study aims to investigate the effect of systemically administrated zoledronate on bone-implant fixation in animal models. Methods:We searched MEDLINE, Embase, and EBSCO for studies that explore the role of systemic or local zoledronate delivery in implant osseointegration in animal models. The Review Ma...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2019/9541485
更新日期:2019-09-22 00:00:00
abstract::A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/179836
更新日期:2014-01-01 00:00:00
abstract:AIM:To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS:The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazoliu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/687826
更新日期:2014-01-01 00:00:00
abstract::Intervertebral disk disease (IVDD) is a major spine disorder in canines that causes neurological dysfunction, particularly in the thoracolumbar area. Analgesic and anti-inflammatory drugs are typically used to reduce nociceptive signals to decrease canine suffering. Bee venom (BV) has been reported to exert anti-infla...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2015/363801
更新日期:2015-01-01 00:00:00
abstract::Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediter...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/839019
更新日期:2014-01-01 00:00:00
abstract::A potent fibrinolytic enzyme-producing Bacillus cereus IND1 was isolated from the Indian food, rice. Solid-state fermentation was carried out using agroresidues for the production of fibrinolytic enzyme. Among the substrates, wheat bran supported more enzyme production and has been used for the optimized enzyme produc...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/725064
更新日期:2014-01-01 00:00:00
abstract::Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/140327
更新日期:2013-01-01 00:00:00
abstract::[This retracts the article DOI: 10.1155/2019/5879089.]. ...
journal_title:BioMed research international
pub_type: 撤回出版物
doi:10.1155/2020/5014928
更新日期:2020-08-26 00:00:00