CD44 gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic features.

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：Purpose:To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods:A retrospective analysis was conducted in 34 eyes from 24 progressive...

journal_title：BioMed research international

authors： Wang J,Li Z,Zhang H,Gao N,Mu G

更新日期：2019-04-03 00:00:00

abstract：Background:The chromobox (CBX) proteins CBX2, CBX4, CBX6, CBX7, and CBX8, also known as Polycomb (Pc) proteins, are canonical components of the Polycomb repressive complex 1 (PRC1). Abundant evidence indicates that abnormal expression of Pc proteins is associated with a variety of tumors, but their role in the pathogen...

journal_title：BioMed research international

authors： Tan C,Bei C,Zhu X,Zhang Y,Qin L,Tan S

更新日期：2019-05-09 00:00:00

abstract：:Peroxisome proliferators-activated receptor (PPAR) gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63...

journal_title：BioMed research international

authors： Zhou T,Yan X,Wang G,Liu H,Gan X,Zhang T,Wang J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim of this study was to analyze the effect of sodium arsenite (NaAsO2) ...

journal_title：BioMed research international

authors： Gutiérrez-Torres DS,González-Horta C,Del Razo LM,Infante-Ramírez R,Ramos-Martínez E,Levario-Carrillo M,Sánchez-Ramírez B

更新日期：2015-01-01 00:00:00

abstract：:To protect against the environmental pollution, the present research was undertaken to enumerate the Bacterial Technologies (BTs) on the restoration of polluted urban rivers, that is, Fenghu-Song Yang River (FSR) and Xuxi River (XXR). Experimental research accounted for the physiochemical parameters (pH; temperature; ...

journal_title：BioMed research international

authors： Hashim S,Yuebo X,Ahmad F,Arslan C,Saifullah M

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study was to investigate whether the use of HLA as an aqueous binder of hydroxyapatite/beta-tricalcium phosphate (HA-βTCP) particles can reduce the amount of bone graft needed and increase ease of handling in clinical situations. In this study, HA/βTCP was loaded in commercially available crosslink...

journal_title：BioMed research international

authors： Chang YL,Lo YJ,Feng SW,Huang YC,Tsai HY,Lin CT,Fan KH,Huang HM

更新日期：2016-01-01 00:00:00

abstract：Purpose:To explore the effect of VEGF (vascular endothelial growth factor) on the vasculogenic mimicry (VM) formation of Choroidal Melanoma (CM) through PI3k signal pathway, to find novel targets for CM therapy. Methods:This research investigated the molecular mechanism of VEGF promoting VM formation of CM. First, we ...

journal_title：BioMed research international

authors： Xu X,Zong Y,Gao Y,Sun X,Zhao H,Luo W,Jia S

更新日期：2019-07-11 00:00:00

abstract：PURPOSE:This study was designed to evaluate the role of maintenance therapy with partially hydrolyzed guar gum (PHGG) after topical application of glyceryl trinitrate (GTN) in the conservative treatment of chronic anal fissure (CAF). METHODS:From all the patients with CAF observed during the study period, 165 subjects...

journal_title：BioMed research international

authors： Brillantino A,Iacobellis F,Izzo G,Di Martino N,Grassi R,Renzi A

更新日期：2014-01-01 00:00:00

abstract：:(i) Purpose. The fluid challenge (FC) is a well-established test of preload reserve. Only limited data exist in regard to the FC efficacy based on infusion time. Slow administration may be associated with lack of effect based on fluid redistribution and external conditions changes. On the contrary, fast administration...

journal_title：BioMed research international

authors： Pouska J,Tegl V,Astapenko D,Cerny V,Lehmann C,Benes J

更新日期：2018-11-01 00:00:00

abstract：:Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement....

journal_title：BioMed research international

authors： Nisticò S,Campolmi P,Moretti S,Del Duca E,Bruscino N,Conti R,Bassi A,Cannarozzo G

更新日期：2016-01-01 00:00:00

abstract：:The present study evaluated the anti-inflammatory and analgesic effects of the superoxide dismutase mimetic agent tempol in superoxide anion-induced pain and inflammation. Mice were treated intraperitoneally with tempol (10-100 mg/kg) 40 min before the intraplantar injection of a superoxide anion donor, potassium supe...

journal_title：BioMed research international

authors： Bernardy CCF,Zarpelon AC,Pinho-Ribeiro FA,Calixto-Campos C,Carvalho TT,Fattori V,Borghi SM,Casagrande R,Verri WA Jr

更新日期：2017-01-01 00:00:00

abstract：:Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and the constancy of the ionic product for water. These rules define the acid-base balance in the human body. According to the electroneutrality principle, plasma has to be electrically neutral and th...

journal_title：BioMed research international

authors： Adeva-Andany MM,Carneiro-Freire N,Donapetry-García C,Rañal-Muíño E,López-Pereiro Y

更新日期：2014-01-01 00:00:00

abstract：:Diosmin has been widely used to treat patients with vascular pain for its potent anti-inflammatory and analgesic effects. To evaluate the therapeutic effects of Diosmin in the treatment of radicular pain, we conducted an investigator-initiated, randomized, active-controlled noninferiority trial between January 1, 2009...

journal_title：BioMed research international

authors： Wang Y,Fang X,Ye L,Li Y,Shi H,Cao Y

更新日期：2017-01-01 00:00:00

abstract：:A standard protocol of dosimetric measurements is used by the organizations responsible for verifying that the doses delivered in radiation-therapy institutions are within authorized limits. This study evaluated a self-designed simple auditing phantom for use in verifying the dose of radiation therapy; the phantom des...

journal_title：BioMed research international

authors： Lee JH,Chang LT,Shiau AC,Chen CW,Liao YJ,Li WJ,Lee MS,Hsu SM

更新日期：2015-01-01 00:00:00

abstract：:Metabolomics is the sophisticated and high-throughput technology based on the entire set of metabolites which is known as the connector between genotypes and phenotypes. For any phenotypic changes, potential metabolite (biomarker) identification is very important because it provides diagnostic as well as prognostic ma...

journal_title：BioMed research international

authors： Kumar N,Hoque MA,Shahjaman M,Islam SM,Mollah MN

更新日期：2017-01-01 00:00:00

abstract：:It is well known that Down syndrome (DS) is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Intellectual disability is the foremost and most debilitating trait, which caused loss of cognitive abilities and the development of early onset Alzheimer's d...

journal_title：BioMed research international

authors： Yu B,Zhang B,Zhou WB,Wang QW,Yuan P,Yang YQ,Kong J

更新日期：2015-01-01 00:00:00

abstract：:The monoexponential model is widely used in quantitative biomedical imaging. Notable applications include apparent diffusion coefficient (ADC) imaging and pharmacokinetics. The application of ADC imaging to the detection of malignant tissue has in turn prompted several studies concerning optimal experiment design for ...

journal_title：BioMed research international

authors： Alipoor M,Maier SE,Gu IY,Mehnert A,Kahl F

更新日期：2015-01-01 00:00:00

abstract：:Mung bean is a hepatoprotective agent in dietary supplements. Fermentation and germination processes are well recognized to enhance the nutritional values especially the concentration of active compounds such as amino acids and GABA of various foods. In this study, antioxidant and hepatoprotective effects of freeze-dr...

journal_title：BioMed research international

authors： Mohd Ali N,Mohd Yusof H,Long K,Yeap SK,Ho WY,Beh BK,Koh SP,Abdullah MP,Alitheen NB

更新日期：2013-01-01 00:00:00

abstract：:Poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be successful agents in inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached clinical trial testing for treatment in different cancers, and, recently, Olaparib (AZD2281) has gained both United States Food and Drug Admini...

journal_title：BioMed research international

authors： Murata S,Zhang C,Finch N,Zhang K,Campo L,Breuer EK

更新日期：2016-01-01 00:00:00

abstract：:The effect of Cordyceps militaris (CM) grown on germinated soybeans (GSC) in the inflammatory bowel disease (IBD) model was studied. To demonstrate the preventive effect of GSC extract in a dextran-sodium-sulfate- (DSS-) induced acute colitis mouse model, GSC was administered 2 days before DSS coadministration. GSC si...

journal_title：BioMed research international

authors： Park DK,Park HJ

更新日期：2013-01-01 00:00:00

abstract：:Adult orthodontics may confront problems related to the bonding performance of orthodontic brackets to new generation restorative materials used for crown or laminate restorations. The aim of the present study was to investigate the shear bond strength of ceramic brackets to two new generation CAD/CAM interpenetrating...

journal_title：BioMed research international

authors： Özarslan MM,Üstün Ö,Buyukkaplan US,Barutcigil Ç,Türker N,Barutcigil K

更新日期：2018-05-30 00:00:00

abstract：:The plant cytoskeleton, including microtubules and microfilaments, is one of the important factors in determining the polarity of cell division and growth, as well as the interaction of plants with invading pathogens. In defense responses of wheat against the stripe rust (Puccinia striiformis f. sp. tritici) infection...

journal_title：BioMed research international

authors： Wang J,Wang Y,Liu X,Xu Y,Ma Q

更新日期：2016-01-01 00:00:00

abstract：:Sophora davidii (Franch.) Kom. ex Pavol is an important medicinal plant and a feeding scrub with ecological value. The effects of different gamma irradiation doses (20-140 Kr) on seed germination and seedling morphology were investigated in S. davidii, and intersimple sequence repeat (ISSR) markers were used to identi...

journal_title：BioMed research international

authors： Wang P,Zhang Y,Zhao L,Mo B,Luo T

更新日期：2017-01-01 00:00:00

abstract：:Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English...

journal_title：BioMed research international

authors： Abate M,Schiavone C,Salini V

更新日期：2014-01-01 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00

abstract：:The aging process causes a number of changes in the skin, including oxidative stress and dyschromia. The kojic acid (KA) is iron chelator employed in treatment of skin aging, and inhibits tyrosinase, promotes depigmentation. Nanotechnology-based drug delivery systems, such as liquid crystalline systems (LCSs), can mod...

journal_title：BioMed research international

authors： Gonçalez ML,Corrêa MA,Chorilli M

更新日期：2013-01-01 00:00:00

abstract：:Melanoma is a human skin malignant tumor with high invasion and poor prognosis. The limited understanding of genomic alterations in melanomas in China impedes the diagnosis and therapeutic strategy selection. We conducted comprehensive genomic profiling of melanomas from 39 primary and metastatic formalin-fixed paraff...

journal_title：BioMed research international

authors： Luo Y,Zhang Z,Liu J,Li L,Xu X,Yao X,Dai Z,Wang X,Yang S,Wu H,Bu J,Wu Y,Xiang T,Li X

更新日期：2020-01-30 00:00:00

abstract：Objective:This study aims to (i) translate, culturally adapt, and preliminarily validate the arrhythmia-specific Umea22 (U22) questionnaire and (ii) assess the impact of radiofrequency (RF) ablation and medical treatment on the quality of life of patients with supraventricular tachycardias (SVTs). Methods:A total of 1...

journal_title：BioMed research international

authors： Domeyer PR,Giannakidou SC,Kyriakou P,Katsari V,Antoniadis AP,Lagos IK,Fragakis N,Varaklioti A,Vassilikos VP

更新日期：2018-10-09 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a multisystemic granulomatous disorder characterized by multiple noncaseating granulomas involving intrathoracic lymph nodes and lung parenchyma. Recently, the use of anti-tumor necrosis factor alpha (anti-TNFα) agents has been introduced for therapy of chronic and refractory sarcoidosis wit...

journal_title：BioMed research international

authors： Galli F,Lanzolla T,Pietrangeli V,Malviya G,Ricci A,Bruno P,Ragni P,Scopinaro F,Mariotta S,Signore A

更新日期：2015-01-01 00:00:00